{"id":"https://openalex.org/W1515524351","doi":"https://doi.org/10.1109/csb.2003.1227333","title":"Anticlustal: multiple sequence alignment by antipole clustering and linear approximate 1-median computation","display_name":"Anticlustal: multiple sequence alignment by antipole clustering and linear approximate 1-median computation","publication_year":2004,"publication_date":"2004-03-30","ids":{"openalex":"https://openalex.org/W1515524351","doi":"https://doi.org/10.1109/csb.2003.1227333","mag":"1515524351","pmid":"https://pubmed.ncbi.nlm.nih.gov/16452808"},"language":"en","primary_location":{"id":"doi:10.1109/csb.2003.1227333","is_oa":false,"landing_page_url":"https://doi.org/10.1109/csb.2003.1227333","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050770412","display_name":"Cinzia Di Pietro","orcid":"https://orcid.org/0000-0002-6036-4469"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"C. Di Pietro","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007788517","display_name":"Valentina Di Pietro","orcid":"https://orcid.org/0000-0001-9430-4723"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V. Di Pietro","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038874834","display_name":"Giovanni Emmanuele","orcid":"https://orcid.org/0000-0002-4090-9230"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Emmanuele","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000272110","display_name":"Alfredo Ferro","orcid":"https://orcid.org/0000-0002-9431-5788"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Ferro","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036101333","display_name":"Teresa L. Maugeri","orcid":null},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"T. Maugeri","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080200189","display_name":"E. Modica","orcid":null},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E. Modica","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023231783","display_name":"Giuseppe Pigola","orcid":null},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G. Pigola","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057481978","display_name":"Alfredo Pulvirenti","orcid":"https://orcid.org/0000-0002-9764-0295"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. Pulvirenti","raw_affiliation_strings":["Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento di Matematica e Informatica, Universit\u00e0 di, Catania","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"Dipartimento di Matematica e, Informatica Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040548022","display_name":"Michele Purrello","orcid":"https://orcid.org/0000-0001-8873-3660"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Purrello","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060302514","display_name":"Maria Alessandra Ragusa","orcid":"https://orcid.org/0000-0001-6611-6370"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Ragusa","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014385269","display_name":"Marina Scalia","orcid":"https://orcid.org/0000-0003-1742-1373"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Scalia","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055576104","display_name":"Dennis Shasha","orcid":"https://orcid.org/0000-0002-7036-3312"},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]},{"id":"https://openalex.org/I36672615","display_name":"Courant Institute of Mathematical Sciences","ror":"https://ror.org/037tm7f56","country_code":"US","type":"education","lineage":["https://openalex.org/I36672615","https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Shasha","raw_affiliation_strings":["Courant Institute of Mathematical Science, New York University, USA"],"affiliations":[{"raw_affiliation_string":"Courant Institute of Mathematical Science, New York University, USA","institution_ids":["https://openalex.org/I36672615","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111737531","display_name":"S. Travali","orcid":null},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Travali","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032793436","display_name":"Vincenzo Zimmitti","orcid":null},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V. Zimmitti","raw_affiliation_strings":["Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Dipartimento, di Scienze Biomediche, Universit\u00e0 di Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5050770412"],"corresponding_institution_ids":["https://openalex.org/I39063666"],"apc_list":null,"apc_paid":null,"fwci":0.7235,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.66520338,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"22","issue":null,"first_page":"326","last_page":"336"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.726657509803772},{"id":"https://openalex.org/keywords/multiple-sequence-alignment","display_name":"Multiple sequence alignment","score":0.6392822265625},{"id":"https://openalex.org/keywords/computation","display_name":"Computation","score":0.5984517335891724},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5578055381774902},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.5367468595504761},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.5216549038887024},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.4934619963169098},{"id":"https://openalex.org/keywords/metric","display_name":"Metric (unit)","score":0.4470781087875366},{"id":"https://openalex.org/keywords/time-complexity","display_name":"Time complexity","score":0.4304288327693939},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.41791510581970215},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.36175355315208435},{"id":"https://openalex.org/keywords/sequence-alignment","display_name":"Sequence alignment","score":0.3509284257888794},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.19789248704910278},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.15921908617019653}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.726657509803772},{"id":"https://openalex.org/C88031987","wikidata":"https://www.wikidata.org/wiki/Q1377767","display_name":"Multiple sequence alignment","level":5,"score":0.6392822265625},{"id":"https://openalex.org/C45374587","wikidata":"https://www.wikidata.org/wiki/Q12525525","display_name":"Computation","level":2,"score":0.5984517335891724},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5578055381774902},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5367468595504761},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.5216549038887024},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4934619963169098},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.4470781087875366},{"id":"https://openalex.org/C311688","wikidata":"https://www.wikidata.org/wiki/Q2393193","display_name":"Time complexity","level":2,"score":0.4304288327693939},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.41791510581970215},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.36175355315208435},{"id":"https://openalex.org/C45484198","wikidata":"https://www.wikidata.org/wiki/Q827246","display_name":"Sequence alignment","level":4,"score":0.3509284257888794},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.19789248704910278},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.15921908617019653},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017421","descriptor_name":"Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017421","descriptor_name":"Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017421","descriptor_name":"Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1109/csb.2003.1227333","is_oa":false,"landing_page_url":"https://doi.org/10.1109/csb.2003.1227333","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003","raw_type":"proceedings-article"},{"id":"pmid:16452808","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16452808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. IEEE Computer Society Bioinformatics Conference","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land","score":0.6899999976158142}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W938539187","https://openalex.org/W1422803820","https://openalex.org/W1525759724","https://openalex.org/W1969153299","https://openalex.org/W1974326986","https://openalex.org/W1990061958","https://openalex.org/W2008803097","https://openalex.org/W2036295979","https://openalex.org/W2038044292","https://openalex.org/W2041076979","https://openalex.org/W2062202510","https://openalex.org/W2097706568","https://openalex.org/W2106882534","https://openalex.org/W2108215151","https://openalex.org/W2127070656","https://openalex.org/W2155237411","https://openalex.org/W6628537349","https://openalex.org/W6652511434","https://openalex.org/W6674647444"],"related_works":["https://openalex.org/W2051969447","https://openalex.org/W2111937814","https://openalex.org/W2162923930","https://openalex.org/W1482324242","https://openalex.org/W2133116680","https://openalex.org/W2091678889","https://openalex.org/W2029514038","https://openalex.org/W2149492307","https://openalex.org/W1985408726","https://openalex.org/W2141411672"],"abstract_inverted_index":{"In":[0,145],"this":[1],"paper":[2],"we":[3],"present":[4],"a":[5,45,121,147,167,174],"new":[6],"Multiple":[7,61],"Sequence":[8],"Alignment":[9],"(MSA)":[10],"algorithm":[11,115,149,162],"called":[12,150],"AntiClusAl.":[13],"The":[14,49,80,109],"method":[15],"makes":[16,67],"use":[17,21,68,119],"of":[18,23,58,69,77,82,85,90,112,120,194],"the":[19,38,56,59,70,74,78,88,94],"commonly":[20],"idea":[22,111],"aligning":[24],"homologous":[25],"sequences":[26,86],"belonging":[27],"to":[28,117,136,171],"classes":[29],"generated":[30],"by":[31],"some":[32],"clustering":[33,148],"algorithm,":[34],"and":[35,123,153],"then":[36,53],"continue":[37],"alignment":[39,63,72,182],"process":[40],"ina":[41],"bottom-up":[42],"way":[43],"along":[44],"suitable":[46],"tree":[47,152],"structure.":[48],"final":[50],"result":[51],"is":[52,87,116,198],"read":[54],"at":[55],"root":[57],"tree.":[60],"sequence":[62,100],"in":[64,101,141],"each":[65],"cluster":[66],"progressive":[71],"with":[73,164,179],"1-median":[75,81,157],"(center)":[76],"cluster.":[79],"set":[83],"S":[84,91],"element":[89],"which":[92,131],"minimizes":[93],"average":[95],"distance":[96],"from":[97],"any":[98],"other":[99],"S.":[102],"Its":[103],"exact":[104],"computation":[105,158],"requires":[106],"quadratic":[107],"time.":[108],"basic":[110],"our":[113],"proposed":[114],"make":[118],"simple":[122],"natural":[124],"algorithmic":[125],"technique":[126],"based":[127],"on":[128],"randomized":[129],"tournaments":[130],"has":[132],"been":[133],"successfully":[134],"applied":[135],"large":[137],"size":[138],"search":[139],"problems":[140],"general":[142],"metric":[143],"spaces.":[144],"particular":[146],"Antipole":[151],"an":[154],"approximate":[155],"linear":[156],"are":[159],"used.":[160],"Our":[161],"compared":[163],"Clustal":[165],"W,":[166],"widely":[168],"used":[169],"tool":[170],"MSA,":[172],"shows":[173],"better":[175],"running":[176],"time":[177],"results":[178],"fully":[180],"comparable":[181],"quality.":[183],"A":[184],"successful":[185],"biological":[186],"application":[187],"showing":[188],"high":[189],"aminoacid":[190],"conservation":[191],"during":[192],"evolution":[193],"Xenopus":[195],"laevis":[196],"SOD2":[197],"also":[199],"cited.":[200]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}