{"id":"https://openalex.org/W2935126842","doi":"https://doi.org/10.1109/conielecomp.2019.8673128","title":"Optical methods and image processing as a quantitative tool in photodynamic therapy: a proof of concept","display_name":"Optical methods and image processing as a quantitative tool in photodynamic therapy: a proof of concept","publication_year":2019,"publication_date":"2019-02-01","ids":{"openalex":"https://openalex.org/W2935126842","doi":"https://doi.org/10.1109/conielecomp.2019.8673128","mag":"2935126842"},"language":"en","primary_location":{"id":"doi:10.1109/conielecomp.2019.8673128","is_oa":false,"landing_page_url":"https://doi.org/10.1109/conielecomp.2019.8673128","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 International Conference on Electronics, Communications and Computers (CONIELECOMP)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076368412","display_name":"Josu\u00e9 D. Rivera-Fern\u00e1ndez","orcid":"https://orcid.org/0000-0003-2967-6736"},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Josue D. Rivera-Fernandez","raw_affiliation_strings":["Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064417959","display_name":"Karen Roa-Tort","orcid":"https://orcid.org/0000-0002-6780-6370"},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Karen Roa-Tort","raw_affiliation_strings":["Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033577236","display_name":"J. de la Rosa","orcid":"https://orcid.org/0000-0002-7781-8906"},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Jose M. de la Rosa-Vazquez","raw_affiliation_strings":["Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031444134","display_name":"A. Valor","orcid":"https://orcid.org/0000-0001-6648-7905"},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Alma Valor-Reed","raw_affiliation_strings":["Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028393975","display_name":"S. Stolik","orcid":"https://orcid.org/0000-0003-3353-6015"},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Suren Stolik-Isakina","raw_affiliation_strings":["Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Laboratorio de Biofot\u00f3nica, Instituto Polit\u00e9cnico Nacional ESIME Zacatenco Ciudad de M\u00e9xico, M\u00e9xico","institution_ids":["https://openalex.org/I59361560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066111533","display_name":"Diego A. Fabila-Bustos","orcid":"https://orcid.org/0000-0002-6383-1675"},"institutions":[{"id":"https://openalex.org/I59361560","display_name":"Instituto Polit\u00e9cnico Nacional","ror":"https://ror.org/059sp8j34","country_code":"MX","type":"education","lineage":["https://openalex.org/I59361560"]},{"id":"https://openalex.org/I4210104059","display_name":"Cultura","ror":"https://ror.org/01gjnzx46","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210104059"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Diego A. Fabila-Bustos","raw_affiliation_strings":["Laboratorio de Espectroscop\u00eda, UPIIH, Instituto Polit\u00e9cnico Nacional, Ciudad del Conocimiento y la Cultura, San Agustin Tlaxiaca, Hidalgo, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Laboratorio de Espectroscop\u00eda, UPIIH, Instituto Polit\u00e9cnico Nacional, Ciudad del Conocimiento y la Cultura, San Agustin Tlaxiaca, Hidalgo, M\u00e9xico","institution_ids":["https://openalex.org/I59361560","https://openalex.org/I4210104059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077985235","display_name":"Carolina Guzm\u00e1n","orcid":"https://orcid.org/0000-0001-7658-045X"},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]},{"id":"https://openalex.org/I2802421035","display_name":"Hospital General de M\u00e9xico","ror":"https://ror.org/01php1d31","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I2802421035","https://openalex.org/I4210095685"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Carolina Guzman-Arriaga","raw_affiliation_strings":["Unidad de Medicina Experimental, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Hospital General de M\u00e9xico \"Dr. Eduardo Liceaga\", Ciudad de M\u00e9xico, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Unidad de Medicina Experimental, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Hospital General de M\u00e9xico \"Dr. Eduardo Liceaga\", Ciudad de M\u00e9xico, M\u00e9xico","institution_ids":["https://openalex.org/I2802421035","https://openalex.org/I8961855"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081106690","display_name":"Galileo Escobedo","orcid":"https://orcid.org/0000-0002-9224-7400"},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Galileo Escobedo","raw_affiliation_strings":["Departamento de Inmunolog\u00eda, Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad Universitaria, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Departamento de Inmunolog\u00eda, Instituto de Investigaciones Biom\u00e9dicas, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Ciudad Universitaria, M\u00e9xico","institution_ids":["https://openalex.org/I8961855"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5076368412"],"corresponding_institution_ids":["https://openalex.org/I59361560"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.04675981,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"4","issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9943000078201294,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.9919999837875366,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"Photodynamic therapy","score":0.8556758165359497},{"id":"https://openalex.org/keywords/rgb-color-model","display_name":"RGB color model","score":0.5972952842712402},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5822644233703613},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5214540362358093},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5156906843185425},{"id":"https://openalex.org/keywords/white-light","display_name":"White light","score":0.4975133240222931},{"id":"https://openalex.org/keywords/image-processing","display_name":"Image processing","score":0.46812477707862854},{"id":"https://openalex.org/keywords/fluorescence","display_name":"Fluorescence","score":0.46363016963005066},{"id":"https://openalex.org/keywords/reflectivity","display_name":"Reflectivity","score":0.45219549536705017},{"id":"https://openalex.org/keywords/protoporphyrin-ix","display_name":"Protoporphyrin IX","score":0.41037964820861816},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.3409678339958191},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3306083679199219},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.24662050604820251},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.19025284051895142},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1471278965473175},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.13829585909843445}],"concepts":[{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.8556758165359497},{"id":"https://openalex.org/C82990744","wikidata":"https://www.wikidata.org/wiki/Q166194","display_name":"RGB color model","level":2,"score":0.5972952842712402},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5822644233703613},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5214540362358093},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5156906843185425},{"id":"https://openalex.org/C2984065012","wikidata":"https://www.wikidata.org/wiki/Q23444","display_name":"White light","level":2,"score":0.4975133240222931},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.46812477707862854},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.46363016963005066},{"id":"https://openalex.org/C108597893","wikidata":"https://www.wikidata.org/wiki/Q663650","display_name":"Reflectivity","level":2,"score":0.45219549536705017},{"id":"https://openalex.org/C2779671804","wikidata":"https://www.wikidata.org/wiki/Q619815","display_name":"Protoporphyrin IX","level":3,"score":0.41037964820861816},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3409678339958191},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3306083679199219},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.24662050604820251},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.19025284051895142},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1471278965473175},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.13829585909843445},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/conielecomp.2019.8673128","is_oa":false,"landing_page_url":"https://doi.org/10.1109/conielecomp.2019.8673128","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 International Conference on Electronics, Communications and Computers (CONIELECOMP)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.44999998807907104,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1951796581","https://openalex.org/W1963510680","https://openalex.org/W1976436613","https://openalex.org/W1991767819","https://openalex.org/W2081839214","https://openalex.org/W2095940876","https://openalex.org/W2110005706","https://openalex.org/W2133665775","https://openalex.org/W2151734986","https://openalex.org/W2219513084","https://openalex.org/W2406205248","https://openalex.org/W2522183825","https://openalex.org/W2605568460","https://openalex.org/W2743707604","https://openalex.org/W2795156864","https://openalex.org/W2795202369","https://openalex.org/W2891312470","https://openalex.org/W2917837889","https://openalex.org/W3133924569","https://openalex.org/W6640987521"],"related_works":["https://openalex.org/W3111424859","https://openalex.org/W2110332934","https://openalex.org/W4238855851","https://openalex.org/W4242341064","https://openalex.org/W2130914421","https://openalex.org/W2586129518","https://openalex.org/W3127979394","https://openalex.org/W3148592355","https://openalex.org/W1992141538","https://openalex.org/W1974652418"],"abstract_inverted_index":{"This":[0],"paper":[1],"presents":[2],"the":[3,7,64,79,88,91,96,102,108],"first":[4],"results":[5],"of":[6,9,66,75,81,90,95],"combination":[8],"optical":[10],"techniques,":[11,18],"through":[12],"fluorescence":[13,82],"images":[14],"captured":[15],"by":[16],"endoscopic":[17,85],"and":[19,36,73,107],"imaging":[20],"processing":[21],"methods":[22],"to":[23,32,34,49],"give":[24],"a":[25,58],"quantitative":[26],"result":[27],"that":[28],"will":[29],"be":[30],"useful":[31],"physicians":[33],"observing":[35],"following":[37],"up":[38],"Photodynamic":[39],"Therapy":[40],"(PDT)":[41],"for":[42,63,70,78],"liver":[43],"cancer.":[44],"The":[45],"experiment":[46],"was":[47],"applied":[48],"an":[50],"animal":[51],"model":[52],"using":[53],"\u03b4-aminolevulinic":[54],"acid":[55],"(ALA)":[56],"as":[57,101],"photosensitizing":[59],"agent,":[60],"red":[61],"light":[62,69,74],"application":[65],"PDT,":[67],"white":[68],"diffuse":[71],"reflectance":[72],"405":[76],"nm":[77],"capture":[80],"photographs":[83],"with":[84],"procedures":[86],"on":[87],"surface":[89],"liver.":[92],"As":[93],"part":[94],"image":[97],"processing,":[98],"metrics":[99],"such":[100],"Euclidean":[103],"distance":[104],"were":[105],"used":[106],"RGB":[109],"color":[110],"composition":[111],"components.":[112]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}