{"id":"https://openalex.org/W2974497600","doi":"https://doi.org/10.1109/coase.2019.8843147","title":"Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines","display_name":"Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines","publication_year":2019,"publication_date":"2019-08-01","ids":{"openalex":"https://openalex.org/W2974497600","doi":"https://doi.org/10.1109/coase.2019.8843147","mag":"2974497600"},"language":"en","primary_location":{"id":"doi:10.1109/coase.2019.8843147","is_oa":false,"landing_page_url":"https://doi.org/10.1109/coase.2019.8843147","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 15th International Conference on Automation Science and Engineering (CASE)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102020639","display_name":"Mengdi Xu","orcid":"https://orcid.org/0000-0001-6087-7558"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mengdi Xu","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004170925","display_name":"Russell H. Taylor","orcid":"https://orcid.org/0000-0001-6272-1100"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell H. Taylor","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012775344","display_name":"Gregory S. Chirikjian","orcid":"https://orcid.org/0000-0003-0542-9028"},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Gregory S. Chirikjian","raw_affiliation_strings":["Dept. of Mechanical Engineering, National University of Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Mechanical Engineering, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009231552","display_name":"Shengnan Lyu","orcid":"https://orcid.org/0000-0002-5990-6144"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shengnan Lyu","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083176966","display_name":"XU Ying-tian","orcid":null},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yingtian Xu","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010006862","display_name":"Can Kocabalkanli","orcid":null},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Can Kocabalkanli","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098648555","display_name":"Brian K. Chirikjian","orcid":null},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian K. Chirikjian","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000964497","display_name":"John S. Chirikjian","orcid":null},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John S. Chirikjian","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069339454","display_name":"Joshua D. Davis","orcid":"https://orcid.org/0000-0001-6276-3976"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Davis","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015341073","display_name":"Jin Seob Kim","orcid":"https://orcid.org/0000-0001-5091-2014"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jin Seob Kim","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063913520","display_name":"Iulian Iordachita","orcid":"https://orcid.org/0000-0002-2510-9008"},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iulian Iordachita","raw_affiliation_strings":["The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Laboratory for Computational Sensing and Robotics (LCSR), Johns Hopkins University, 3400 N Charles St. Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1262,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.80174394,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"2 1","issue":null,"first_page":"443","last_page":"449"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11663","display_name":"Viral Infectious Diseases and Gene Expression in Insects","score":0.9901000261306763,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.9836000204086304,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malaria-vaccine","display_name":"Malaria vaccine","score":0.6384344696998596},{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.6091604828834534},{"id":"https://openalex.org/keywords/anopheles-stephensi","display_name":"Anopheles stephensi","score":0.5297979712486267},{"id":"https://openalex.org/keywords/automation","display_name":"Automation","score":0.4979703426361084},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.418582946062088},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4163845479488373},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.3982626795768738},{"id":"https://openalex.org/keywords/aedes-aegypti","display_name":"Aedes aegypti","score":0.2357177734375},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2210548222064972},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.16488197445869446},{"id":"https://openalex.org/keywords/mechanical-engineering","display_name":"Mechanical engineering","score":0.1438511610031128},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.1399150788784027},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.10219842195510864}],"concepts":[{"id":"https://openalex.org/C2781034427","wikidata":"https://www.wikidata.org/wiki/Q6741353","display_name":"Malaria vaccine","level":4,"score":0.6384344696998596},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.6091604828834534},{"id":"https://openalex.org/C2780478335","wikidata":"https://www.wikidata.org/wiki/Q4115863","display_name":"Anopheles stephensi","level":4,"score":0.5297979712486267},{"id":"https://openalex.org/C115901376","wikidata":"https://www.wikidata.org/wiki/Q184199","display_name":"Automation","level":2,"score":0.4979703426361084},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.418582946062088},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4163845479488373},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3982626795768738},{"id":"https://openalex.org/C2777775583","wikidata":"https://www.wikidata.org/wiki/Q1148004","display_name":"Aedes aegypti","level":3,"score":0.2357177734375},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2210548222064972},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.16488197445869446},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.1438511610031128},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.1399150788784027},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.10219842195510864},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/coase.2019.8843147","is_oa":false,"landing_page_url":"https://doi.org/10.1109/coase.2019.8843147","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 15th International Conference on Automation Science and Engineering (CASE)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7900000214576721}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1870963173","https://openalex.org/W1902761939","https://openalex.org/W1979427692","https://openalex.org/W2119855808","https://openalex.org/W2346928357","https://openalex.org/W2571810950","https://openalex.org/W2588256621","https://openalex.org/W2922763470","https://openalex.org/W2973839948","https://openalex.org/W2974096238","https://openalex.org/W6731820500","https://openalex.org/W6760888924"],"related_works":["https://openalex.org/W2131277865","https://openalex.org/W2088582527","https://openalex.org/W4401623603","https://openalex.org/W2954706416","https://openalex.org/W2405847924","https://openalex.org/W2942187201","https://openalex.org/W2178803407","https://openalex.org/W3217358840","https://openalex.org/W4400408704","https://openalex.org/W4319459473"],"abstract_inverted_index":{"This":[0,16,82],"paper":[1],"describes":[2],"the":[3,27,37,40,64,72,76,87,100,104,121,132],"design":[4],"of":[5,20,75,124,134],"a":[6,31,44],"fully":[7],"automated":[8],"apparatus":[9],"to":[10,34,39,50,53,107,130],"dispense":[11],"mosquitoes":[12,38,52],"into":[13],"isolate":[14],"units.":[15],"automation":[17,83],"system":[18,84],"consists":[19],"several":[21],"process":[22],"units":[23],"including":[24],"(1)":[25],"facilitating":[26],"water":[28],"vortex":[29],"with":[30,43],"fan-shape":[32],"rotor":[33],"gently":[35],"transport":[36],"sorting":[41],"slides":[42,49],"conical":[45],"geometry,":[46],"(2)":[47],"exploiting":[48],"guide":[51],"turntables":[54],"driven":[55],"by":[56,59,79],"gears":[57],"one":[58],"one,":[60],"and":[61],"(3)":[62],"reorienting":[63],"mosquito":[65,93,101],"until":[66],"its":[67],"proboscis":[68],"points":[69],"outward":[70],"along":[71],"radial":[73],"direction":[74],"cone,":[77],"aided":[78],"computer":[80],"vision.":[81],"serves":[85],"as":[86],"first":[88,110],"processing":[89],"stage":[90],"for":[91],"collecting":[92],"salivary":[94],"glands.":[95],"The":[96,114],"sporozoites":[97],"contained":[98],"in":[99],"glands":[102],"are":[103],"source":[105],"material":[106],"produce":[108],"Sanaria's":[109],"generation":[111],"PfSPZ":[112],"vaccines.":[113],"Mosquito":[115],"Staging":[116],"System":[117],"can":[118],"dramatically":[119],"enhance":[120],"mass":[122],"production":[123],"Malaria":[125],"Vaccine":[126],"which":[127],"is":[128],"essential":[129],"prevent":[131],"propagation":[133],"Malaria.":[135]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}