{"id":"https://openalex.org/W1965027570","doi":"https://doi.org/10.1109/coase.2012.6386455","title":"A vacuum-pumped microfluidic device for automated in-line mixing and focusing processes","display_name":"A vacuum-pumped microfluidic device for automated in-line mixing and focusing processes","publication_year":2012,"publication_date":"2012-08-01","ids":{"openalex":"https://openalex.org/W1965027570","doi":"https://doi.org/10.1109/coase.2012.6386455","mag":"1965027570"},"language":"en","primary_location":{"id":"doi:10.1109/coase.2012.6386455","is_oa":false,"landing_page_url":"https://doi.org/10.1109/coase.2012.6386455","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Automation Science and Engineering (CASE)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113633565","display_name":"An\u2010Shik Yang","orcid":null},"institutions":[{"id":"https://openalex.org/I118292597","display_name":"National Taipei University of Technology","ror":"https://ror.org/00cn92c09","country_code":"TW","type":"education","lineage":["https://openalex.org/I118292597"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"An-Shik Yang","raw_affiliation_strings":["Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","institution_ids":["https://openalex.org/I118292597"]},{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C","institution_ids":["https://openalex.org/I118292597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029768799","display_name":"Hao-Hung Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I118292597","display_name":"National Taipei University of Technology","ror":"https://ror.org/00cn92c09","country_code":"TW","type":"education","lineage":["https://openalex.org/I118292597"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hao-Hung Huang","raw_affiliation_strings":["Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","institution_ids":["https://openalex.org/I118292597"]},{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C","institution_ids":["https://openalex.org/I118292597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110128013","display_name":"Li-Yu Tseng","orcid":null},"institutions":[{"id":"https://openalex.org/I118292597","display_name":"National Taipei University of Technology","ror":"https://ror.org/00cn92c09","country_code":"TW","type":"education","lineage":["https://openalex.org/I118292597"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Li-Yu Tseng","raw_affiliation_strings":["Institute of Mechatronic Engineering, National Taipei University of Technology, Taipei, Taiwan","Institute of Mechatronic Engineering, National Taipei University of Technology, National Taipei University of Technology, 106, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Mechatronic Engineering, National Taipei University of Technology, Taipei, Taiwan","institution_ids":["https://openalex.org/I118292597"]},{"raw_affiliation_string":"Institute of Mechatronic Engineering, National Taipei University of Technology, National Taipei University of Technology, 106, Taiwan, R.O.C","institution_ids":["https://openalex.org/I118292597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059971981","display_name":"Po-Hung Liu","orcid":"https://orcid.org/0000-0003-3531-4686"},"institutions":[{"id":"https://openalex.org/I118292597","display_name":"National Taipei University of Technology","ror":"https://ror.org/00cn92c09","country_code":"TW","type":"education","lineage":["https://openalex.org/I118292597"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Po-Hung Liu","raw_affiliation_strings":["Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","institution_ids":["https://openalex.org/I118292597"]},{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C","institution_ids":["https://openalex.org/I118292597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055986785","display_name":"Tsai-Lung Su","orcid":null},"institutions":[{"id":"https://openalex.org/I118292597","display_name":"National Taipei University of Technology","ror":"https://ror.org/00cn92c09","country_code":"TW","type":"education","lineage":["https://openalex.org/I118292597"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Tsai-Lung Su","raw_affiliation_strings":["Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","institution_ids":["https://openalex.org/I118292597"]},{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C","institution_ids":["https://openalex.org/I118292597"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035931882","display_name":"Chun-Lung Li","orcid":null},"institutions":[{"id":"https://openalex.org/I118292597","display_name":"National Taipei University of Technology","ror":"https://ror.org/00cn92c09","country_code":"TW","type":"education","lineage":["https://openalex.org/I118292597"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chun-Lung Li","raw_affiliation_strings":["Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, Taipei, Taiwan","institution_ids":["https://openalex.org/I118292597"]},{"raw_affiliation_string":"Department of Energy and Refrigerating Air-Conditioning Engineering, National Taipei University of Technology, 106, Taiwan, R.O.C","institution_ids":["https://openalex.org/I118292597"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I118292597"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05341727,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"136","issue":null,"first_page":"109","last_page":"114"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12452","display_name":"Electrowetting and Microfluidic Technologies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/micromixer","display_name":"Micromixer","score":0.9443007707595825},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.9080896377563477},{"id":"https://openalex.org/keywords/microchannel","display_name":"Microchannel","score":0.8092618584632874},{"id":"https://openalex.org/keywords/mixing","display_name":"Mixing (physics)","score":0.7613863945007324},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6042593717575073},{"id":"https://openalex.org/keywords/lab-on-a-chip","display_name":"Lab-on-a-chip","score":0.5487533211708069},{"id":"https://openalex.org/keywords/lithography","display_name":"Lithography","score":0.46079474687576294},{"id":"https://openalex.org/keywords/planar","display_name":"Planar","score":0.43287068605422974},{"id":"https://openalex.org/keywords/optoelectronics","display_name":"Optoelectronics","score":0.391859233379364},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.362702876329422},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3217431902885437},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09794217348098755}],"concepts":[{"id":"https://openalex.org/C2780982322","wikidata":"https://www.wikidata.org/wiki/Q3312230","display_name":"Micromixer","level":3,"score":0.9443007707595825},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.9080896377563477},{"id":"https://openalex.org/C63662833","wikidata":"https://www.wikidata.org/wiki/Q6839341","display_name":"Microchannel","level":2,"score":0.8092618584632874},{"id":"https://openalex.org/C138777275","wikidata":"https://www.wikidata.org/wiki/Q6884054","display_name":"Mixing (physics)","level":2,"score":0.7613863945007324},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6042593717575073},{"id":"https://openalex.org/C138942068","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Lab-on-a-chip","level":3,"score":0.5487533211708069},{"id":"https://openalex.org/C204223013","wikidata":"https://www.wikidata.org/wiki/Q133036","display_name":"Lithography","level":2,"score":0.46079474687576294},{"id":"https://openalex.org/C134786449","wikidata":"https://www.wikidata.org/wiki/Q3391255","display_name":"Planar","level":2,"score":0.43287068605422974},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.391859233379364},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.362702876329422},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3217431902885437},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09794217348098755},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/coase.2012.6386455","is_oa":false,"landing_page_url":"https://doi.org/10.1109/coase.2012.6386455","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Automation Science and Engineering (CASE)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","display_name":"Affordable and clean energy","score":0.4000000059604645}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321040","display_name":"National Science Council","ror":"https://ror.org/02kv4zf79"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1973956312","https://openalex.org/W1986412261","https://openalex.org/W1995137593","https://openalex.org/W2012452399","https://openalex.org/W2012646266","https://openalex.org/W2026087730","https://openalex.org/W2035022333","https://openalex.org/W2043844615","https://openalex.org/W2060147473","https://openalex.org/W2060673671","https://openalex.org/W2062392012","https://openalex.org/W2086162031","https://openalex.org/W2086896805","https://openalex.org/W2098990516","https://openalex.org/W2113214121","https://openalex.org/W2115307447","https://openalex.org/W2125049832","https://openalex.org/W2141063938","https://openalex.org/W2540977196","https://openalex.org/W4240011078"],"related_works":["https://openalex.org/W4293217337","https://openalex.org/W2800789064","https://openalex.org/W2082428072","https://openalex.org/W3210806854","https://openalex.org/W3201583168","https://openalex.org/W2998011576","https://openalex.org/W2059212966","https://openalex.org/W3198451916","https://openalex.org/W3085731770","https://openalex.org/W2038796934"],"abstract_inverted_index":{"Microfluidic":[0],"devices":[1],"with":[2,80],"multi-functional":[3],"features":[4],"have":[5,158],"been":[6],"a":[7,22,37,44,48,94,136,151,169,180],"highly":[8],"promising":[9],"tool":[10],"to":[11,52,86,100,116,141,167,174],"implement":[12],"mixing,":[13],"reaction,":[14],"transport,":[15],"separation,":[16],"and":[17,31,47,60,112,135,155,173],"detection":[18],"of":[19,43,58,67,162,182],"bio-samples":[20],"on":[21,150],"solitary":[23],"microchip":[24],"for":[25,63,122],"applications":[26],"in":[27,106,185],"the":[28,68,73,97,109,118,124,127,146,160,163,176],"biochemistry,":[29],"biophysics":[30],"medical":[32],"fields.":[33],"This":[34],"work":[35],"presents":[36],"unified":[38],"vacuum-pumped":[39],"microfluidic":[40,128,165],"device":[41,129,166],"consisting":[42],"micromixer":[45,79],"module":[46,51,99],"microflow":[49],"cytometer":[50],"complete":[53],"an":[54,76],"automated":[55],"in-line":[56],"sequence":[57],"mixing":[59,89,111,171],"focusing":[61,105,114],"procedures":[62],"possible":[64],"rapid":[65],"screening":[66],"marker":[69],"cell":[70],"detection.":[71],"For":[72],"former":[74],"module,":[75],"in-plane":[77],"passive":[78],"optimum":[81],"Tesla":[82],"structures":[83,144],"was":[84,130],"adopted":[85],"achieve":[87],"good":[88],"performance.":[90],"We":[91],"also":[92],"devised":[93],"microcytometer":[95],"as":[96],"latter":[98],"attain":[101],"planar":[102],"symmetric":[103],"hydrodynamic":[104,113],"microchannels.":[107],"Using":[108],"coupled":[110],"analysis":[115],"predict":[117],"suction-driven":[119],"flow":[120],"behavior":[121],"guiding":[123],"chip":[125],"design,":[126],"fabricated":[131],"through":[132],"SU-8":[133,148],"lithography":[134],"PDMS":[137],"replica":[138],"molding":[139],"technique":[140],"construct":[142],"reverse":[143],"from":[145],"patterned":[147],"molds":[149],"silicon":[152],"substrate.":[153],"Numerical":[154],"experimental":[156],"results":[157],"demonstrated":[159],"capability":[161],"developed":[164],"realize":[168],"93%":[170],"index":[172],"control":[175],"focused":[177],"stream":[178],"within":[179],"width":[181],"20":[183],"\u03bcm":[184],"tests.":[186]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}