{"id":"https://openalex.org/W4410492982","doi":"https://doi.org/10.1109/cicc63670.2025.10983564","title":"A Fully-Integrated Wireless Ingestible Drug Delivery Chip with Electrochemical Energy Harvesting and pH-Based MPPT","display_name":"A Fully-Integrated Wireless Ingestible Drug Delivery Chip with Electrochemical Energy Harvesting and pH-Based MPPT","publication_year":2025,"publication_date":"2025-04-13","ids":{"openalex":"https://openalex.org/W4410492982","doi":"https://doi.org/10.1109/cicc63670.2025.10983564"},"language":"en","primary_location":{"id":"doi:10.1109/cicc63670.2025.10983564","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cicc63670.2025.10983564","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE Custom Integrated Circuits Conference (CICC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010371644","display_name":"So\u2010Yoon Yang","orcid":"https://orcid.org/0000-0001-9185-3014"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"So-Yoon Yang","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077262787","display_name":"Deniz Umut Y\u0131ld\u0131r\u0131m","orcid":"https://orcid.org/0000-0002-2160-1142"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deniz Umut Yildirim","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081684813","display_name":"Saransh Sharma","orcid":"https://orcid.org/0000-0002-5052-4932"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saransh Sharma","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039062148","display_name":"Donghyeon Han","orcid":"https://orcid.org/0000-0002-5212-2072"},"institutions":[{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Donghyeon Han","raw_affiliation_strings":["Chung-ang University,Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Chung-ang University,Republic of Korea","institution_ids":["https://openalex.org/I67900169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031891091","display_name":"Rishabh Mittal","orcid":"https://orcid.org/0009-0001-6815-9128"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rishabh Mittal","raw_affiliation_strings":["MediaTek,USA"],"affiliations":[{"raw_affiliation_string":"MediaTek,USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114187943","display_name":"Husna Ellis","orcid":null},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Husna Ellis","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059645690","display_name":"Jaehong Jung","orcid":"https://orcid.org/0000-0003-3690-4901"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaehong Jung","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015550942","display_name":"Eunseok Lee","orcid":"https://orcid.org/0000-0002-6557-8087"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eunseok Lee","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102361437","display_name":"Yubin Cai","orcid":null},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yubin Cai","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028026814","display_name":"Giovanni Traverso","orcid":"https://orcid.org/0000-0001-7851-4077"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giovanni Traverso","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5097749541","display_name":"Anantha P. Chandrakasan","orcid":null},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anantha P. Chandrakasan","raw_affiliation_strings":["Massachusetts Institute of Technology,USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts Institute of Technology,USA","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5010371644"],"corresponding_institution_ids":["https://openalex.org/I63966007"],"apc_list":null,"apc_paid":null,"fwci":1.4772,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.82732856,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11392","display_name":"Energy Harvesting in Wireless Networks","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11392","display_name":"Energy Harvesting in Wireless Networks","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10338","display_name":"Advanced Sensor and Energy Harvesting Materials","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wireless","display_name":"Wireless","score":0.6156864762306213},{"id":"https://openalex.org/keywords/chip","display_name":"Chip","score":0.593347430229187},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5364686846733093},{"id":"https://openalex.org/keywords/energy-harvesting","display_name":"Energy harvesting","score":0.52369225025177},{"id":"https://openalex.org/keywords/system-on-a-chip","display_name":"System on a chip","score":0.4820328950881958},{"id":"https://openalex.org/keywords/maximum-power-point-tracking","display_name":"Maximum power point tracking","score":0.4359831213951111},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.35923221707344055},{"id":"https://openalex.org/keywords/energy","display_name":"Energy (signal processing)","score":0.30833524465560913},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.2495083212852478},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2083226442337036},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.18592709302902222},{"id":"https://openalex.org/keywords/voltage","display_name":"Voltage","score":0.11474016308784485},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.1078401505947113}],"concepts":[{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.6156864762306213},{"id":"https://openalex.org/C165005293","wikidata":"https://www.wikidata.org/wiki/Q1074500","display_name":"Chip","level":2,"score":0.593347430229187},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5364686846733093},{"id":"https://openalex.org/C101518730","wikidata":"https://www.wikidata.org/wiki/Q930236","display_name":"Energy harvesting","level":3,"score":0.52369225025177},{"id":"https://openalex.org/C118021083","wikidata":"https://www.wikidata.org/wiki/Q610398","display_name":"System on a chip","level":2,"score":0.4820328950881958},{"id":"https://openalex.org/C36139824","wikidata":"https://www.wikidata.org/wiki/Q1052007","display_name":"Maximum power point tracking","level":4,"score":0.4359831213951111},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.35923221707344055},{"id":"https://openalex.org/C186370098","wikidata":"https://www.wikidata.org/wiki/Q442787","display_name":"Energy (signal processing)","level":2,"score":0.30833524465560913},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.2495083212852478},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2083226442337036},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.18592709302902222},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.11474016308784485},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1078401505947113},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C11190779","wikidata":"https://www.wikidata.org/wiki/Q664575","display_name":"Inverter","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cicc63670.2025.10983564","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cicc63670.2025.10983564","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE Custom Integrated Circuits Conference (CICC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7","score":0.6299999952316284}],"awards":[{"id":"https://openalex.org/G1562519603","display_name":null,"funder_award_id":"FA8650-21-2-7120","funder_id":"https://openalex.org/F4320332815","funder_display_name":"Advanced Research Projects Agency"}],"funders":[{"id":"https://openalex.org/F4320332815","display_name":"Advanced Research Projects Agency","ror":"https://ror.org/02caytj08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W2079510199","https://openalex.org/W2129638745","https://openalex.org/W2295251306","https://openalex.org/W2587707451","https://openalex.org/W2898326745","https://openalex.org/W2904227508","https://openalex.org/W3126551253","https://openalex.org/W4388342031","https://openalex.org/W4389542822"],"related_works":["https://openalex.org/W2206043812","https://openalex.org/W2805575148","https://openalex.org/W2145087841","https://openalex.org/W4296710271","https://openalex.org/W3154871000","https://openalex.org/W3018308121","https://openalex.org/W2065289416","https://openalex.org/W2017236304","https://openalex.org/W2115579119","https://openalex.org/W2136854845"],"abstract_inverted_index":{"Advances":[0],"in":[1,16,101,239],"personalized":[2],"medicine":[3],"are":[4,97],"spurring":[5],"the":[6,17,138,156,163,204,208,214,219,223,232,236],"development":[7],"of":[8,143,149,158,162,196,207,222],"ingestible":[9,65],"electronics":[10],"for":[11,46,99,130,173,217],"controlled,":[12],"on-demand":[13],"drug":[14,35,93,134,178],"delivery":[15,94,135],"gastrointestinal":[18],"(GI)":[19],"tract,":[20],"enhancing":[21],"therapeutic":[22],"efficacy":[23],"further":[24,230],"beyond":[25],"traditional":[26],"oral":[27],"pills.":[28],"These":[29],"systems":[30,225],"rely":[31],"on":[32],"electronically":[33],"controlled":[34],"release":[36],"actuation":[37,95],"mechanisms,":[38],"like":[39,133],"micropumps":[40],"[1]":[41],"and":[42,57,77,91,151,194],"reservoir-based":[43,181],"designs":[44],"[2],":[45,154,211],"precision":[47],"dosing":[48],"[3],":[49],"[4].":[50],"However,":[51,137,213],"they":[52,67],"often":[53],"require":[54],"substantial":[55],"energy":[56,75,88,113,122,175],"space":[58],"[5].":[59],"While":[60],"conventional":[61],"batteries":[62],"have":[63],"powered":[64],"electronics,":[66],"pose":[68],"challenges":[69],"due":[70],"to":[71,166,234],"their":[72],"bulkiness,":[73],"limited":[74],"density,":[76],"safety":[78],"risks":[79],"associated":[80],"with":[81,184,228],"toxic":[82],"materials":[83],"[6],":[84],"[7].":[85],"Consequently,":[86],"battery-free":[87],"harvesting":[89],"solutions":[90],"energy-efficient":[92],"mechanisms":[96],"crucial":[98],"progress":[100],"this":[102],"field.":[103],"Among":[104],"other":[105],"energy-harvesting":[106],"methods,":[107],"such":[108,199],"as":[109,200],"thermal":[110],"or":[111],"vibrational":[112],"harvesters,":[114],"a":[115,146,180,191],"galvanic":[116],"cell":[117],"(GC),":[118],"which":[119],"converts":[120],"chemical":[121],"from":[123,203],"acidic":[124],"GI":[125,164,209,237],"fluid,":[126],"is":[127,145],"particularly":[128],"well-suited":[129],"high-power":[131],"applications":[132],"[6].":[136],"maximum":[139,168],"power":[140,169],"point":[141,170],"(MPP)":[142],"GC":[144],"nonlinear":[147],"function":[148],"pH":[150,160,238],"opencircuit":[152],"voltage":[153,216],"necessitating":[155],"sampling":[157],"real-time":[159,240],"data":[161],"fluid":[165],"perform":[167],"tracking":[171],"(MPPT)":[172],"efficient":[174],"harvesting.":[176],"For":[177],"delivery,":[179],"system":[182],"sealed":[183],"an":[185],"electrochemically":[186],"dissolvable":[187],"metal":[188,220],"membrane":[189,221],"offers":[190],"compact":[192],"design":[193],"protection":[195],"sensitive":[197],"payloads":[198],"unstable":[201],"drugs":[202],"harsh":[205],"environment":[206],"tract":[210],"[8].":[212],"activation":[215],"dissolving":[218],"reservoirbased":[224],"also":[226],"varies":[227],"pH,":[229],"highlighting":[231],"need":[233],"sample":[235],"[9].":[241]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-03-27T14:29:43.386196","created_date":"2025-10-10T00:00:00"}