{"id":"https://openalex.org/W2967085371","doi":"https://doi.org/10.1109/cibcb.2019.8791492","title":"Genetic Algorithm for Optimizing Global Alignment of Protein-Protein Interaction Network","display_name":"Genetic Algorithm for Optimizing Global Alignment of Protein-Protein Interaction Network","publication_year":2019,"publication_date":"2019-07-01","ids":{"openalex":"https://openalex.org/W2967085371","doi":"https://doi.org/10.1109/cibcb.2019.8791492","mag":"2967085371"},"language":"en","primary_location":{"id":"doi:10.1109/cibcb.2019.8791492","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2019.8791492","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056019959","display_name":"Qanita Bani Baker","orcid":"https://orcid.org/0000-0003-4722-6632"},"institutions":[{"id":"https://openalex.org/I156983542","display_name":"Jordan University of Science and Technology","ror":"https://ror.org/03y8mtb59","country_code":"JO","type":"education","lineage":["https://openalex.org/I156983542"]}],"countries":["JO"],"is_corresponding":true,"raw_author_name":"Qanita Bani Baker","raw_affiliation_strings":["Department of Computer Science, Jordan University of Science and Technology, Irbid, Jordan"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Jordan University of Science and Technology, Irbid, Jordan","institution_ids":["https://openalex.org/I156983542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077835497","display_name":"Manar K Al-Bataineh","orcid":null},"institutions":[{"id":"https://openalex.org/I156983542","display_name":"Jordan University of Science and Technology","ror":"https://ror.org/03y8mtb59","country_code":"JO","type":"education","lineage":["https://openalex.org/I156983542"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Manar K Al-Bataineh","raw_affiliation_strings":["Department of Computer Science, Jordan University of Science and Technology, Irbid, Jordan"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Jordan University of Science and Technology, Irbid, Jordan","institution_ids":["https://openalex.org/I156983542"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5056019959"],"corresponding_institution_ids":["https://openalex.org/I156983542"],"apc_list":null,"apc_paid":null,"fwci":0.0852,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.46718737,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"30","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/correctness","display_name":"Correctness","score":0.8164136409759521},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7444844245910645},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.5754510164260864},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.5750157237052917},{"id":"https://openalex.org/keywords/greedy-algorithm","display_name":"Greedy algorithm","score":0.5559216737747192},{"id":"https://openalex.org/keywords/genetic-algorithm","display_name":"Genetic algorithm","score":0.5325065851211548},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.45822298526763916},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4003481864929199},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3808104395866394},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3419470191001892}],"concepts":[{"id":"https://openalex.org/C55439883","wikidata":"https://www.wikidata.org/wiki/Q360812","display_name":"Correctness","level":2,"score":0.8164136409759521},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7444844245910645},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.5754510164260864},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5750157237052917},{"id":"https://openalex.org/C51823790","wikidata":"https://www.wikidata.org/wiki/Q504353","display_name":"Greedy algorithm","level":2,"score":0.5559216737747192},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.5325065851211548},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.45822298526763916},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4003481864929199},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3808104395866394},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3419470191001892},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cibcb.2019.8791492","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2019.8791492","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.44999998807907104,"display_name":"Responsible consumption and production","id":"https://metadata.un.org/sdg/12"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1686696692","https://openalex.org/W1971937094","https://openalex.org/W1984249061","https://openalex.org/W2014374374","https://openalex.org/W2014553879","https://openalex.org/W2024060531","https://openalex.org/W2039616005","https://openalex.org/W2039872058","https://openalex.org/W2041020482","https://openalex.org/W2043795984","https://openalex.org/W2055043387","https://openalex.org/W2056124433","https://openalex.org/W2092986233","https://openalex.org/W2119151462","https://openalex.org/W2128408632","https://openalex.org/W2130237248","https://openalex.org/W2137648512","https://openalex.org/W2139361324","https://openalex.org/W2141185847","https://openalex.org/W2144362290","https://openalex.org/W2153929049","https://openalex.org/W2158714788","https://openalex.org/W2165253681","https://openalex.org/W2171255489","https://openalex.org/W2254156100","https://openalex.org/W2566782168","https://openalex.org/W2583540866"],"related_works":["https://openalex.org/W4387497383","https://openalex.org/W3183948672","https://openalex.org/W3173606202","https://openalex.org/W3110381201","https://openalex.org/W2948807893","https://openalex.org/W2935909890","https://openalex.org/W2778153218","https://openalex.org/W2758277628","https://openalex.org/W1531601525","https://openalex.org/W2114062695"],"abstract_inverted_index":{"Protein-protein":[0],"interactions":[1],"can":[2],"be":[3],"modeled":[4],"as":[5,47],"networks.":[6,137],"The":[7,63,108,138],"huge":[8],"amount":[9],"of":[10,33,66,86,99,110,131,134],"produced":[11],"Protein-Protein":[12],"Interaction":[13],"(PPI)data":[14],"has":[15],"many":[16],"applications":[17],"in":[18,26,105],"biological":[19,49],"studies.":[20],"These":[21],"studies":[22,35],"improved":[23,92],"human":[24],"knowledge":[25],"the":[27,42,82,95,100,111,120,125,129,132,135,142,151],"life":[28],"process":[29,127],"and":[30,77,84,103,128,145],"diseases.":[31],"One":[32],"these":[34,52],"is":[36,54,72,114],"PPI":[37,45,69,88],"network":[38,70,89],"alignment,":[39],"which":[40],"finds":[41],"similarity":[43],"between":[44],"networks":[46,53],"a":[48],"similarity.":[50],"Aligning":[51],"important":[55],"to":[56,73,150],"investigate":[57],"evolutionary":[58],"pathways":[59],"or":[60],"protein":[61],"complexes.":[62],"main":[64],"challenge":[65],"all":[67],"global":[68,87],"alignment":[71,90,126],"improve":[74],"both":[75],"accuracy":[76,83,144],"efficiency.":[78],"In":[79],"this":[80],"research,":[81],"efficiency":[85],"are":[91],"by":[93],"using":[94],"genetic":[96],"algorithm":[97,102],"instead":[98],"greedy":[101],"applied":[104],"HubAlign":[106,117,152],"framework.":[107],"performance":[109],"proposed":[112],"method":[113],"compared":[115,149],"with":[116],"based":[118],"on":[119],"total":[121],"execution":[122,147],"time":[123,148],"for":[124],"correctness":[130],"results":[133],"aligned":[136],"new":[139],"approach":[140],"enhanced":[141],"overall":[143],"reduce":[146],"approach.":[153]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}