{"id":"https://openalex.org/W1907763804","doi":"https://doi.org/10.1109/cibcb.2015.7300271","title":"Detecting protein complexes using gene expression biclusters","display_name":"Detecting protein complexes using gene expression biclusters","publication_year":2015,"publication_date":"2015-08-01","ids":{"openalex":"https://openalex.org/W1907763804","doi":"https://doi.org/10.1109/cibcb.2015.7300271","mag":"1907763804"},"language":"en","primary_location":{"id":"doi:10.1109/cibcb.2015.7300271","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2015.7300271","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056412439","display_name":"Eileen Marie Hanna","orcid":"https://orcid.org/0000-0002-2093-4586"},"institutions":[{"id":"https://openalex.org/I201726411","display_name":"United Arab Emirates University","ror":"https://ror.org/01km6p862","country_code":"AE","type":"education","lineage":["https://openalex.org/I201726411"]}],"countries":["AE"],"is_corresponding":true,"raw_author_name":"Eileen Marie Hanna","raw_affiliation_strings":["College of Information Technology United Arab Emirates University, Al Ain, UAE","College of Information Technology, United Arab Emirates University, Al Ain 17551, UAE"],"affiliations":[{"raw_affiliation_string":"College of Information Technology United Arab Emirates University, Al Ain, UAE","institution_ids":["https://openalex.org/I201726411"]},{"raw_affiliation_string":"College of Information Technology, United Arab Emirates University, Al Ain 17551, UAE","institution_ids":["https://openalex.org/I201726411"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040640075","display_name":"Nazar Zaki","orcid":"https://orcid.org/0000-0002-6259-9843"},"institutions":[{"id":"https://openalex.org/I201726411","display_name":"United Arab Emirates University","ror":"https://ror.org/01km6p862","country_code":"AE","type":"education","lineage":["https://openalex.org/I201726411"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Nazar M. Zaki","raw_affiliation_strings":["College of Information Technology United Arab Emirates University, Al Ain, UAE","College of Information Technology, United Arab Emirates University, Al Ain 17551, UAE"],"affiliations":[{"raw_affiliation_string":"College of Information Technology United Arab Emirates University, Al Ain, UAE","institution_ids":["https://openalex.org/I201726411"]},{"raw_affiliation_string":"College of Information Technology, United Arab Emirates University, Al Ain 17551, UAE","institution_ids":["https://openalex.org/I201726411"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5056412439"],"corresponding_institution_ids":["https://openalex.org/I201726411"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.03438045,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"3","issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5057775974273682},{"id":"https://openalex.org/keywords/protein-expression","display_name":"Protein expression","score":0.4451451003551483},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.44199639558792114},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.43413257598876953},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3431776762008667},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3289128541946411},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2812085747718811}],"concepts":[{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5057775974273682},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.4451451003551483},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.44199639558792114},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.43413257598876953},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3431776762008667},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3289128541946411},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2812085747718811}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cibcb.2015.7300271","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2015.7300271","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W86501616","https://openalex.org/W1493217831","https://openalex.org/W1541754351","https://openalex.org/W1555424131","https://openalex.org/W1578407488","https://openalex.org/W1595210477","https://openalex.org/W1973508741","https://openalex.org/W1977556410","https://openalex.org/W1983043794","https://openalex.org/W1987546980","https://openalex.org/W1993445335","https://openalex.org/W2010950448","https://openalex.org/W2022892561","https://openalex.org/W2023720664","https://openalex.org/W2024624328","https://openalex.org/W2036799174","https://openalex.org/W2050721857","https://openalex.org/W2057514122","https://openalex.org/W2057682468","https://openalex.org/W2058849889","https://openalex.org/W2072163224","https://openalex.org/W2080278541","https://openalex.org/W2082565035","https://openalex.org/W2090257125","https://openalex.org/W2095588912","https://openalex.org/W2097520363","https://openalex.org/W2103017472","https://openalex.org/W2104039751","https://openalex.org/W2107067224","https://openalex.org/W2107710781","https://openalex.org/W2114324579","https://openalex.org/W2115108153","https://openalex.org/W2118258530","https://openalex.org/W2119359534","https://openalex.org/W2121564430","https://openalex.org/W2129795133","https://openalex.org/W2131323902","https://openalex.org/W2132582966","https://openalex.org/W2132993044","https://openalex.org/W2136850043","https://openalex.org/W2139779649","https://openalex.org/W2140280811","https://openalex.org/W2141012957","https://openalex.org/W2144544802","https://openalex.org/W2147109452","https://openalex.org/W2148636094","https://openalex.org/W2152495216","https://openalex.org/W2152556351","https://openalex.org/W2156960886","https://openalex.org/W2162032011","https://openalex.org/W2165232124","https://openalex.org/W2165533101","https://openalex.org/W2611370172","https://openalex.org/W2786876516","https://openalex.org/W4244000367","https://openalex.org/W6603519168","https://openalex.org/W6629329278","https://openalex.org/W6635477257"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2131250617","https://openalex.org/W4233034052","https://openalex.org/W2371030422","https://openalex.org/W2065530813","https://openalex.org/W2803323662","https://openalex.org/W3032874291","https://openalex.org/W2005057264","https://openalex.org/W2363156284","https://openalex.org/W2415025170"],"abstract_inverted_index":{"The":[0,23,140],"importance":[1],"of":[2,44,109,123,150],"detecting":[3,50],"protein":[4,7,51,82,124],"complexes":[5,25,152],"in":[6,19,61,80,95],"interaction":[8,83,125],"networks":[9,84,92,126],"originates":[10],"from":[11],"the":[12,28,41,45,75,78,107],"fact":[13,104],"that":[14,77,144],"they":[15],"are":[16,85,93],"key":[17],"players":[18],"most":[20],"cellular":[21],"processes.":[22],"more":[24],"we":[26,30,114],"identify,":[27],"better":[29,154],"can":[31],"understand":[32],"normal":[33],"as":[34,36],"well":[35],"abnormal":[37],"molecular":[38],"events.":[39],"Despite":[40],"notable":[42],"performance":[43],"current":[46],"computational":[47],"methods":[48],"for":[49],"complexes,":[52],"questions":[53],"arise":[54],"regarding":[55],"potential":[56],"ways":[57],"to":[58,63,66,74,101,105,119,136,147],"improve":[59],"them,":[60],"addition":[62],"ameliorative":[64],"guidelines":[65],"introduce":[67],"novel":[68],"approaches.":[69],"A":[70],"close":[71],"interpretation":[72],"leads":[73,146],"assent":[76],"way":[79],"which":[81],"initially":[86],"viewed":[87],"should":[88],"be":[89],"adjusted.":[90],"These":[91],"dynamic":[94,121],"reality":[96],"and":[97],"it":[98],"is":[99],"necessary":[100],"consider":[102],"this":[103,112],"enhance":[106],"detection":[108],"complexes.":[110],"In":[111],"paper,":[113],"present":[115],"\u201cDyCluster\u201d,":[116],"a":[117],"framework":[118],"model":[120],"aspect":[122],"by":[127],"incorporating":[128],"gene":[129],"expression":[130],"data,":[131],"through":[132],"biclustering":[133],"techniques,":[134],"prior":[135],"applying":[137],"complex-detection":[138],"algorithms.":[139],"experimental":[141],"results":[142],"show":[143],"DyCluster":[145],"higher":[148],"numbers":[149],"correctly-detected":[151],"with":[153],"evaluation":[155],"scores.":[156]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}