{"id":"https://openalex.org/W2062409243","doi":"https://doi.org/10.1109/cibcb.2010.5510587","title":"Supervised learning of maternal cigarette-smoking signatures from placental gene expression data: A case study","display_name":"Supervised learning of maternal cigarette-smoking signatures from placental gene expression data: A case study","publication_year":2010,"publication_date":"2010-05-01","ids":{"openalex":"https://openalex.org/W2062409243","doi":"https://doi.org/10.1109/cibcb.2010.5510587","mag":"2062409243"},"language":"en","primary_location":{"id":"doi:10.1109/cibcb.2010.5510587","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2010.5510587","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111152604","display_name":"Chengpeng Bi","orcid":null},"institutions":[{"id":"https://openalex.org/I75421653","display_name":"University of Missouri\u2013Kansas City","ror":"https://ror.org/01w0d5g70","country_code":"US","type":"education","lineage":["https://openalex.org/I75421653"]},{"id":"https://openalex.org/I1328594524","display_name":"Children's Mercy Hospital","ror":"https://ror.org/04zfmcq84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328594524"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chengpeng Bi","raw_affiliation_strings":["The Division of Clinical Pharmacology, Childrens Mercy Hospitals and Clinics School of Medicine, University of Missouri, Kansas City, MO, USA","Division of Clinical Pharmacology, Children's Mercy Hospitals and Clinics, School of Medicine, University of Missouri, Kansas City, Missouri, USA"],"affiliations":[{"raw_affiliation_string":"The Division of Clinical Pharmacology, Childrens Mercy Hospitals and Clinics School of Medicine, University of Missouri, Kansas City, MO, USA","institution_ids":["https://openalex.org/I1328594524","https://openalex.org/I75421653"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Children's Mercy Hospitals and Clinics, School of Medicine, University of Missouri, Kansas City, Missouri, USA","institution_ids":["https://openalex.org/I75421653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007114974","display_name":"Carrie A. Vyhlidal","orcid":null},"institutions":[{"id":"https://openalex.org/I1328594524","display_name":"Children's Mercy Hospital","ror":"https://ror.org/04zfmcq84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328594524"]},{"id":"https://openalex.org/I75421653","display_name":"University of Missouri\u2013Kansas City","ror":"https://ror.org/01w0d5g70","country_code":"US","type":"education","lineage":["https://openalex.org/I75421653"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carrie Vyhlidal","raw_affiliation_strings":["The Division of Clinical Pharmacology, Childrens Mercy Hospitals and Clinics School of Medicine, University of Missouri, Kansas City, MO, USA","Division of Clinical Pharmacology, Children's Mercy Hospitals and Clinics, School of Medicine, University of Missouri, Kansas City, Missouri, USA"],"affiliations":[{"raw_affiliation_string":"The Division of Clinical Pharmacology, Childrens Mercy Hospitals and Clinics School of Medicine, University of Missouri, Kansas City, MO, USA","institution_ids":["https://openalex.org/I1328594524","https://openalex.org/I75421653"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Children's Mercy Hospitals and Clinics, School of Medicine, University of Missouri, Kansas City, Missouri, USA","institution_ids":["https://openalex.org/I75421653"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112166345","display_name":"Steve Leeder","orcid":null},"institutions":[{"id":"https://openalex.org/I75421653","display_name":"University of Missouri\u2013Kansas City","ror":"https://ror.org/01w0d5g70","country_code":"US","type":"education","lineage":["https://openalex.org/I75421653"]},{"id":"https://openalex.org/I1328594524","display_name":"Children's Mercy Hospital","ror":"https://ror.org/04zfmcq84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1328594524"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steve Leeder","raw_affiliation_strings":["The Division of Clinical Pharmacology, Childrens Mercy Hospitals and Clinics School of Medicine, University of Missouri, Kansas City, MO, USA","Division of Clinical Pharmacology, Children's Mercy Hospitals and Clinics, School of Medicine, University of Missouri, Kansas City, Missouri, USA"],"affiliations":[{"raw_affiliation_string":"The Division of Clinical Pharmacology, Childrens Mercy Hospitals and Clinics School of Medicine, University of Missouri, Kansas City, MO, USA","institution_ids":["https://openalex.org/I1328594524","https://openalex.org/I75421653"]},{"raw_affiliation_string":"Division of Clinical Pharmacology, Children's Mercy Hospitals and Clinics, School of Medicine, University of Missouri, Kansas City, Missouri, USA","institution_ids":["https://openalex.org/I75421653"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5111152604"],"corresponding_institution_ids":["https://openalex.org/I1328594524","https://openalex.org/I75421653"],"apc_list":null,"apc_paid":null,"fwci":0.3965,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.62042221,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9261999726295471,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.737549901008606},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7010654807090759},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6025762557983398},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5605040192604065},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5448813438415527},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5426945090293884},{"id":"https://openalex.org/keywords/linear-discriminant-analysis","display_name":"Linear discriminant analysis","score":0.5315214395523071},{"id":"https://openalex.org/keywords/supervised-learning","display_name":"Supervised learning","score":0.506492018699646},{"id":"https://openalex.org/keywords/data-set","display_name":"Data set","score":0.46382227540016174},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.4415692985057831}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.737549901008606},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7010654807090759},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6025762557983398},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5605040192604065},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5448813438415527},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5426945090293884},{"id":"https://openalex.org/C69738355","wikidata":"https://www.wikidata.org/wiki/Q1228929","display_name":"Linear discriminant analysis","level":2,"score":0.5315214395523071},{"id":"https://openalex.org/C136389625","wikidata":"https://www.wikidata.org/wiki/Q334384","display_name":"Supervised learning","level":3,"score":0.506492018699646},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.46382227540016174},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.4415692985057831}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cibcb.2010.5510587","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2010.5510587","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","score":0.5899999737739563,"display_name":"Reduced inequalities"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1480376833","https://openalex.org/W1554663460","https://openalex.org/W1964168965","https://openalex.org/W1965138864","https://openalex.org/W2074089196","https://openalex.org/W2077658674","https://openalex.org/W2102794349","https://openalex.org/W2104143846","https://openalex.org/W2108728387","https://openalex.org/W2109363337","https://openalex.org/W2110065044","https://openalex.org/W2128040719","https://openalex.org/W2128583125","https://openalex.org/W2153533622","https://openalex.org/W2156909104","https://openalex.org/W2157795344","https://openalex.org/W2167453047","https://openalex.org/W2502655619","https://openalex.org/W2544883878","https://openalex.org/W2787894218","https://openalex.org/W2799061466","https://openalex.org/W4239875977","https://openalex.org/W4294107304","https://openalex.org/W4388297464","https://openalex.org/W6676973524","https://openalex.org/W6679146881"],"related_works":["https://openalex.org/W4402452563","https://openalex.org/W2250488071","https://openalex.org/W2356150353","https://openalex.org/W2090763504","https://openalex.org/W2018643641","https://openalex.org/W2380744779","https://openalex.org/W2967867994","https://openalex.org/W2469878540","https://openalex.org/W2951122819","https://openalex.org/W1481704333"],"abstract_inverted_index":{"This":[0],"paper":[1],"aims":[2],"to":[3,26,42,61,109],"conduct":[4],"supervised":[5,74],"learning":[6,76],"of":[7,47],"the":[8,12,19,28,100,105],"cigarette-smoking":[9,29,106],"signatures":[10],"from":[11],"placental":[13],"gene":[14,38,49,57,68],"expression":[15],"data":[16],"sets":[17,50,58,69],"under":[18],"neural":[20,83],"network":[21,84],"framework":[22],"and":[23,63,86,93],"build":[24],"classifiers":[25],"identify":[27],"moms":[30,107],"during":[31],"pregnancy.":[32],"First,":[33],"a":[34,45],"unified":[35],"model":[36],"for":[37,91],"selection":[39],"is":[40,99],"proposed":[41],"single":[43],"out":[44],"set":[46],"informative":[48,67],"(up-or":[51],"down-regulated":[52],"genes).":[53],"The":[54],"selected":[55],"signature":[56],"are":[59,70],"subject":[60],"refinement,":[62],"then":[64],"so":[65],"refined":[66],"fed":[71],"into":[72],"three":[73],"statistical":[75],"algorithms,":[77],"linear":[78],"discriminant":[79],"function":[80],"(LDF),":[81],"probabilistic":[82],"(PNN)":[85],"support":[87],"vector":[88],"machine":[89],"(SVM)":[90],"training":[92],"testing.":[94],"It":[95],"shows":[96],"that":[97],"SVM":[98],"best":[101],"classifier":[102],"in":[103],"predicting":[104],"compared":[108],"other":[110],"methods":[111],"tested.":[112]},"counts_by_year":[{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}