{"id":"https://openalex.org/W2112600972","doi":"https://doi.org/10.1109/cibcb.2010.5510349","title":"Missing value imputation methods for gene-sample-time microarray data analysis","display_name":"Missing value imputation methods for gene-sample-time microarray data analysis","publication_year":2010,"publication_date":"2010-05-01","ids":{"openalex":"https://openalex.org/W2112600972","doi":"https://doi.org/10.1109/cibcb.2010.5510349","mag":"2112600972"},"language":"en","primary_location":{"id":"doi:10.1109/cibcb.2010.5510349","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2010.5510349","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033510515","display_name":"Yifeng Li","orcid":"https://orcid.org/0000-0002-4873-6928"},"institutions":[{"id":"https://openalex.org/I74413500","display_name":"University of Windsor","ror":"https://ror.org/01gw3d370","country_code":"CA","type":"education","lineage":["https://openalex.org/I74413500"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Yifeng Li","raw_affiliation_strings":["School of Computer Science, University of Windsor, Windsor, ONT, Canada","School of Computer Science, 5115 Lambton Tower, University of Windsor, 401 Sunset Avenue, N9B 3P4, Windsor, Ontario, Canada"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Windsor, Windsor, ONT, Canada","institution_ids":["https://openalex.org/I74413500"]},{"raw_affiliation_string":"School of Computer Science, 5115 Lambton Tower, University of Windsor, 401 Sunset Avenue, N9B 3P4, Windsor, Ontario, Canada","institution_ids":["https://openalex.org/I74413500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070302649","display_name":"Alioune Ngom","orcid":"https://orcid.org/0000-0003-2092-2494"},"institutions":[{"id":"https://openalex.org/I74413500","display_name":"University of Windsor","ror":"https://ror.org/01gw3d370","country_code":"CA","type":"education","lineage":["https://openalex.org/I74413500"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Alioune Ngom","raw_affiliation_strings":["School of Computer Science, University of Windsor, Windsor, ONT, Canada","School of Computer Science, 5115 Lambton Tower, University of Windsor, 401 Sunset Avenue, N9B 3P4, Windsor, Ontario, Canada"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Windsor, Windsor, ONT, Canada","institution_ids":["https://openalex.org/I74413500"]},{"raw_affiliation_string":"School of Computer Science, 5115 Lambton Tower, University of Windsor, 401 Sunset Avenue, N9B 3P4, Windsor, Ontario, Canada","institution_ids":["https://openalex.org/I74413500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040978295","display_name":"Luis Rueda","orcid":"https://orcid.org/0000-0001-7988-2058"},"institutions":[{"id":"https://openalex.org/I74413500","display_name":"University of Windsor","ror":"https://ror.org/01gw3d370","country_code":"CA","type":"education","lineage":["https://openalex.org/I74413500"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Luis Rueda","raw_affiliation_strings":["School of Computer Science, University of Windsor, Windsor, ONT, Canada","School of Computer Science, 5115 Lambton Tower, University of Windsor, 401 Sunset Avenue, N9B 3P4, Windsor, Ontario, Canada"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Windsor, Windsor, ONT, Canada","institution_ids":["https://openalex.org/I74413500"]},{"raw_affiliation_string":"School of Computer Science, 5115 Lambton Tower, University of Windsor, 401 Sunset Avenue, N9B 3P4, Windsor, Ontario, Canada","institution_ids":["https://openalex.org/I74413500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5033510515"],"corresponding_institution_ids":["https://openalex.org/I74413500"],"apc_list":null,"apc_paid":null,"fwci":0.4066,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.63671034,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"32","issue":null,"first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9908999800682068,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.982200026512146,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/missing-data","display_name":"Missing data","score":0.8479392528533936},{"id":"https://openalex.org/keywords/imputation","display_name":"Imputation (statistics)","score":0.7980523109436035},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.6349152326583862},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.6299371123313904},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5671990513801575},{"id":"https://openalex.org/keywords/gene-chip-analysis","display_name":"Gene chip analysis","score":0.4702913761138916},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.35118675231933594},{"id":"https://openalex.org/keywords/microarray","display_name":"Microarray","score":0.32952550053596497},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.29058438539505005},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1514473259449005},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.14279380440711975},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.10524946451187134},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.10129323601722717}],"concepts":[{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.8479392528533936},{"id":"https://openalex.org/C58041806","wikidata":"https://www.wikidata.org/wiki/Q1660484","display_name":"Imputation (statistics)","level":3,"score":0.7980523109436035},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.6349152326583862},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.6299371123313904},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5671990513801575},{"id":"https://openalex.org/C24361400","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Gene chip analysis","level":5,"score":0.4702913761138916},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.35118675231933594},{"id":"https://openalex.org/C186836561","wikidata":"https://www.wikidata.org/wiki/Q1931516","display_name":"Microarray","level":4,"score":0.32952550053596497},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.29058438539505005},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1514473259449005},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14279380440711975},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10524946451187134},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.10129323601722717}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/cibcb.2010.5510349","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2010.5510349","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.337.7582","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.337.7582","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W263545290","https://openalex.org/W598396932","https://openalex.org/W1503537619","https://openalex.org/W1532816937","https://openalex.org/W1969289662","https://openalex.org/W2018407943","https://openalex.org/W2040007196","https://openalex.org/W2096740036","https://openalex.org/W2096863518","https://openalex.org/W2111104102","https://openalex.org/W2114933215","https://openalex.org/W2121159025","https://openalex.org/W2150466754","https://openalex.org/W2171118759","https://openalex.org/W4205465882","https://openalex.org/W6609866339"],"related_works":["https://openalex.org/W2767847608","https://openalex.org/W2361788533","https://openalex.org/W2015700328","https://openalex.org/W2911678823","https://openalex.org/W2057566290","https://openalex.org/W1491323697","https://openalex.org/W1583052686","https://openalex.org/W170658859","https://openalex.org/W2388378880","https://openalex.org/W2378654996"],"abstract_inverted_index":{"With":[0],"the":[1,7,15,67,96,148,152],"recent":[2],"advances":[3],"in":[4,92],"microarray":[5,29,33,45,112],"technology,":[6],"expression":[8],"levels":[9],"of":[10,24,81,90,98],"genes":[11],"with":[12,151],"respect":[13],"to":[14,94,114],"samples":[16],"can":[17],"be":[18,64,76],"monitored":[19],"synchronically":[20],"over":[21],"a":[22],"series":[23],"time":[25],"points.":[26],"Such":[27],"three-dimensional":[28],"data,":[30,70,113],"termed":[31],"gene-sample-time":[32],"data":[34,37,50,91,123],"or":[35,58,71],"GST":[36,69,115,122],"for":[38,110,121],"short,":[39],"may":[40],"contain":[41],"missing":[42,61,73,82],"values.":[43],"Current":[44],"analysis":[46,99],"methods":[47,120,138,143],"require":[48],"complete":[49],"sets,":[51],"and":[52,133,135,140],"thus,":[53],"either":[54],"each":[55],"row,":[56],"column":[57],"tube":[59],"containing":[60],"values":[62,74,83],"must":[63,75],"removed":[65],"from":[66],"original":[68],"these":[72],"estimated":[77],"before":[78],"analysis.":[79],"Imputation":[80],"is,":[84],"however,":[85],"more":[86],"recommended":[87],"than":[88],"removal":[89],"order":[93],"increase":[95],"effectiveness":[97],"algorithms.":[100],"In":[101],"this":[102],"paper,":[103],"we":[104],"extend":[105],"automated":[106],"imputation":[107,119],"methods,":[108],"devised":[109],"two-dimensional":[111],"data.":[116],"We":[117],"implemented":[118],"based":[124,144],"on":[125,145],"Singular":[126],"Value":[127],"Decomposition":[128],"(3SVDimpute),":[129],"K-Nearest":[130],"Neighbor":[131],"(3KNNimpute),":[132],"gene":[134],"sample":[136],"average":[137],"(3Aimpute),":[139],"show":[141],"that":[142],"KNN":[146],"yield":[147],"best":[149],"results":[150],"lowest":[153],"normalized":[154],"root":[155],"mean":[156],"squared":[157],"error.":[158]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}