{"id":"https://openalex.org/W2126941926","doi":"https://doi.org/10.1109/cibcb.2007.4221232","title":"RNA Gene Finding with Biased Mutation Operators","display_name":"RNA Gene Finding with Biased Mutation Operators","publication_year":2007,"publication_date":"2007-04-01","ids":{"openalex":"https://openalex.org/W2126941926","doi":"https://doi.org/10.1109/cibcb.2007.4221232","mag":"2126941926"},"language":"en","primary_location":{"id":"doi:10.1109/cibcb.2007.4221232","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2007.4221232","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE Symposium on Computational Intelligence and Bioinformatics and Computational Biology","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105925430","display_name":"Scott F. Smith","orcid":"https://orcid.org/0009-0005-0495-2716"},"institutions":[{"id":"https://openalex.org/I120156002","display_name":"Boise State University","ror":"https://ror.org/02e3zdp86","country_code":"US","type":"education","lineage":["https://openalex.org/I120156002"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"S.F. Smith","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Boise State University, Boise, ID, USA","Dept. of Electr. & Comput. Eng., Boise State Univ., ID#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Boise State University, Boise, ID, USA","institution_ids":["https://openalex.org/I120156002"]},{"raw_affiliation_string":"Dept. of Electr. & Comput. Eng., Boise State Univ., ID#TAB#","institution_ids":["https://openalex.org/I120156002"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5105925430"],"corresponding_institution_ids":["https://openalex.org/I120156002"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.19175011,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"22","issue":null,"first_page":"268","last_page":"274"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9642999768257141,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covariance","display_name":"Covariance","score":0.6971867084503174},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.5258349180221558},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4615348279476166},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4334741234779358},{"id":"https://openalex.org/keywords/coding","display_name":"Coding (social sciences)","score":0.42954644560813904},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.39451712369918823},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3847798705101013},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3280714154243469},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.28059348464012146},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.14849555492401123}],"concepts":[{"id":"https://openalex.org/C178650346","wikidata":"https://www.wikidata.org/wiki/Q201984","display_name":"Covariance","level":2,"score":0.6971867084503174},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5258349180221558},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4615348279476166},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4334741234779358},{"id":"https://openalex.org/C179518139","wikidata":"https://www.wikidata.org/wiki/Q5140297","display_name":"Coding (social sciences)","level":2,"score":0.42954644560813904},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.39451712369918823},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3847798705101013},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3280714154243469},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28059348464012146},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.14849555492401123}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/cibcb.2007.4221232","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2007.4221232","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE Symposium on Computational Intelligence and Bioinformatics and Computational Biology","raw_type":"proceedings-article"},{"id":"pmh:oai:scholarworks.boisestate.edu:electrical_facpubs-1000","is_oa":false,"landing_page_url":"https://scholarworks.boisestate.edu/electrical_facpubs/1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400258","display_name":"ScholarWorks (Boise State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I120156002","host_organization_name":"Boise State University","host_organization_lineage":["https://openalex.org/I120156002"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Electrical and Computer Engineering Faculty Publications and Presentations","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Peace, Justice and strong institutions","score":0.7099999785423279,"id":"https://metadata.un.org/sdg/16"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1968072881","https://openalex.org/W1989835274","https://openalex.org/W2098005773","https://openalex.org/W2120200808","https://openalex.org/W2158381555","https://openalex.org/W2913974810","https://openalex.org/W3146331408","https://openalex.org/W3147254695","https://openalex.org/W3214380909","https://openalex.org/W4245668478"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2788344745","https://openalex.org/W2062336688","https://openalex.org/W2910677864","https://openalex.org/W2046078371","https://openalex.org/W2383820648","https://openalex.org/W4245445763","https://openalex.org/W3162209258","https://openalex.org/W2146849562","https://openalex.org/W2028961943"],"abstract_inverted_index":{"The":[0,32,133],"use":[1,103],"of":[2,49,64,76,93,104,112,129,135],"genetic":[3,148],"algorithms":[4,149],"for":[5,22],"non-coding":[6,66],"RNA":[7,67],"gene":[8],"finding":[9],"has":[10],"previously":[11],"been":[12],"investigated":[13],"and":[14,42,114,138,146],"found":[15],"to":[16,28,73,153],"be":[17],"a":[18,65,154,159],"potentially":[19],"viable":[20],"method":[21],"accelerating":[23],"covariance-model-based":[24],"database":[25],"search":[26],"relative":[27],"full":[29],"dynamic-programming":[30],"methods.":[31],"mutation":[33,105,140],"operators":[34,106,141],"in":[35,89,127,162],"previous":[36],"work":[37,164],"chose":[38],"new":[39],"alignment":[40],"insertion":[41,121],"deletion":[43,123],"locations":[44],"uniformly":[45],"over":[46],"the":[47,50,55,74,81,90,94,99,102,136],"length":[48],"model":[51,83,117],"consensus":[52],"sequence.":[53],"Since":[54],"covariance":[56,96],"models":[57],"are":[58,108,150],"estimated":[59,95],"from":[60],"multiple":[61],"known":[62],"members":[63],"family,":[68],"information":[69,86],"is":[70,87,125,142,158],"available":[71],"as":[72],"likelihood":[75],"insertions":[77,113],"or":[78,122],"deletions":[79,115],"at":[80,116],"individual":[82],"positions.":[84],"This":[85],"implicit":[88],"state-transition":[91],"parameters":[92],"models.":[97],"In":[98],"current":[100],"work,":[101],"which":[107,157],"biased":[109,137,145],"toward":[110],"selection":[111],"positions":[118],"with":[119],"low":[120],"penalties":[124],"examined":[126],"hopes":[128],"speeding":[130],"up":[131],"convergence.":[132],"performance":[134],"unbiased":[139,147],"compared.":[143],"Both":[144],"also":[151],"compared":[152],"steepest-descent":[155],"algorithm,":[156],"comparison":[160],"lacking":[161],"prior":[163]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-08-01T09:00:35.917206","created_date":"2025-10-10T00:00:00"}