{"id":"https://openalex.org/W2109047523","doi":"https://doi.org/10.1109/cibcb.2004.1393927","title":"Gene expression correlation and gene ontology-based similarity: an assessment of quantitative relationships","display_name":"Gene expression correlation and gene ontology-based similarity: an assessment of quantitative relationships","publication_year":2005,"publication_date":"2005-03-21","ids":{"openalex":"https://openalex.org/W2109047523","doi":"https://doi.org/10.1109/cibcb.2004.1393927","mag":"2109047523","pmid":"https://pubmed.ncbi.nlm.nih.gov/25664345"},"language":"en","primary_location":{"id":"doi:10.1109/cibcb.2004.1393927","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2004.1393927","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IGARSS 2004. 2004 IEEE International Geoscience and Remote Sensing (IEEE Cat. No.04CH37612)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100379058","display_name":"Haiying Wang","orcid":"https://orcid.org/0000-0001-8358-9065"},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"H. Wang","raw_affiliation_strings":["School of Computing and Mathematics, University of Ulster, BT37 0QB, UK","Sch. of Comput. & Math., Ulster Univ., UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing and Mathematics, University of Ulster, BT37 0QB, UK","institution_ids":["https://openalex.org/I138801177"]},{"raw_affiliation_string":"Sch. of Comput. & Math., Ulster Univ., UK","institution_ids":["https://openalex.org/I138801177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050612781","display_name":"Francisco Azuaje","orcid":"https://orcid.org/0000-0002-9207-9072"},"institutions":[{"id":"https://openalex.org/I138801177","display_name":"University of Ulster","ror":"https://ror.org/01yp9g959","country_code":"GB","type":"education","lineage":["https://openalex.org/I138801177"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"F. Azuaje","raw_affiliation_strings":["School of Computing and Mathematics, University of Ulster, BT37 0QB, UK","Sch. of Comput. & Math., Ulster Univ., UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing and Mathematics, University of Ulster, BT37 0QB, UK","institution_ids":["https://openalex.org/I138801177"]},{"raw_affiliation_string":"Sch. of Comput. & Math., Ulster Univ., UK","institution_ids":["https://openalex.org/I138801177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073807945","display_name":"Olivier Bodenreider","orcid":"https://orcid.org/0000-0003-4769-4217"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"O. Bodenreider","raw_affiliation_strings":["U.S. National Library of Medicine, National Institutes of Health, Department of Health & Human Services, 8600 Rockville Pike, Bethesda, Maryland 20894, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"U.S. National Library of Medicine, National Institutes of Health, Department of Health & Human Services, 8600 Rockville Pike, Bethesda, Maryland 20894, U.S.A","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074140420","display_name":"Joaqu\u0131\u0301n Dopazo","orcid":"https://orcid.org/0000-0003-3318-120X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Dopazo","raw_affiliation_strings":["Bioinformatics Unit, Spanish National Cancer Centre (CNIO), Melchor Fernandez Almagro 3, 28039, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics Unit, Spanish National Cancer Centre (CNIO), Melchor Fernandez Almagro 3, 28039, Madrid, Spain","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100379058"],"corresponding_institution_ids":["https://openalex.org/I138801177"],"apc_list":null,"apc_paid":null,"fwci":5.4328,"has_fulltext":false,"cited_by_count":150,"citation_normalized_percentile":{"value":0.96619039,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"2004","issue":null,"first_page":"25","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene ontology","score":0.6764287352561951},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.664982795715332},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5603912472724915},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5586594939231873},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5352490544319153},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.522137463092804},{"id":"https://openalex.org/keywords/correlation","display_name":"Correlation","score":0.5219376087188721},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.5008325576782227},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.462965726852417},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.34534114599227905},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.34449902176856995},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.3349534869194031},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21796321868896484},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.20804014801979065},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.11848139762878418}],"concepts":[{"id":"https://openalex.org/C2987395477","wikidata":"https://www.wikidata.org/wiki/Q135085","display_name":"Gene ontology","level":4,"score":0.6764287352561951},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.664982795715332},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5603912472724915},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5586594939231873},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5352490544319153},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.522137463092804},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.5219376087188721},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5008325576782227},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.462965726852417},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.34534114599227905},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.34449902176856995},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.3349534869194031},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21796321868896484},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20804014801979065},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.11848139762878418},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/cibcb.2004.1393927","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cibcb.2004.1393927","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IGARSS 2004. 2004 IEEE International Geoscience and Remote Sensing (IEEE Cat. No.04CH37612)","raw_type":"proceedings-article"},{"id":"pmid:25664345","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25664345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the ... IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology : CIBCB. IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology","raw_type":null},{"id":"pmh:oai:europepmc.org:3284504","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4317290","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W107544894","https://openalex.org/W1569415500","https://openalex.org/W1597538863","https://openalex.org/W1647729745","https://openalex.org/W1886319227","https://openalex.org/W1950936596","https://openalex.org/W1992763738","https://openalex.org/W2081931663","https://openalex.org/W2082607144","https://openalex.org/W2100935296","https://openalex.org/W2110078328","https://openalex.org/W2112783609","https://openalex.org/W2117720828","https://openalex.org/W2117805756","https://openalex.org/W2123891919","https://openalex.org/W2124388496","https://openalex.org/W2127563440","https://openalex.org/W2128936012","https://openalex.org/W2134788911","https://openalex.org/W2150926065","https://openalex.org/W2159917467","https://openalex.org/W2950225692","https://openalex.org/W4246066782","https://openalex.org/W6634008025","https://openalex.org/W6636975626","https://openalex.org/W6640673246","https://openalex.org/W6675339850","https://openalex.org/W6677712588"],"related_works":["https://openalex.org/W2003333417","https://openalex.org/W2378862226","https://openalex.org/W118236634","https://openalex.org/W2355326633","https://openalex.org/W2804669904","https://openalex.org/W2149777447","https://openalex.org/W2347456287","https://openalex.org/W2121651557","https://openalex.org/W2782969047","https://openalex.org/W2794019507"],"abstract_inverted_index":{"Genome":[0],"Database":[1],"were":[2,20,34],"analyzed":[3],"to":[4,101],"calculate":[5],"functional":[6,60,102],"similarity":[7,15,26,67,79,99],"of":[8,30,32,52,58,95,109,116],"gene":[9,39,53,74,97,110],"products.":[10],"Three":[11],"methods":[12,100],"for":[13],"measuring":[14],"(including":[16],"a":[17,37,78],"distance-based":[18],"approach)":[19],"implemented.":[21],"Significant,":[22],"quantitative":[23],"relationships":[24],"between":[25,86],"and":[27,113],"expression":[28,40,111],"correlation":[29],"pairs":[31,51],"genes":[33,64],"detected.":[35],"Using":[36],"known":[38],"dataset":[41],"in":[42,119],"yeast,":[43],"this":[44],"study":[45,91],"compared":[46],"more":[47],"than":[48,83],"three":[49],"million":[50],"products":[54],"on":[55,69],"the":[56,73,93,107,114],"basis":[57],"these":[59],"properties.":[61],"Highly":[62],"correlated":[63,88],"exhibit":[65],"strong":[66],"based":[68],"information":[70],"originating":[71],"from":[72],"ontology":[75],"taxonomies.":[76],"Such":[77],"is":[80],"significantly":[81],"stronger":[82],"that":[84],"observed":[85],"weakly":[87],"genes.":[89],"This":[90],"supports":[92],"feasibility":[94],"applying":[96],"ontology-driven":[98],"prediction":[103],"tasks,":[104],"such":[105],"as":[106],"validation":[108],"analyses":[112],"identification":[115],"false":[117],"positives":[118],"protein":[120],"interaction":[121],"studies.":[122]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":15},{"year":2012,"cited_by_count":17}],"updated_date":"2026-05-24T08:33:08.758527","created_date":"2025-10-10T00:00:00"}