{"id":"https://openalex.org/W2168843981","doi":"https://doi.org/10.1109/cec.2011.5949901","title":"A hybrid evolutionary approach to protein structure prediction with lattice models","display_name":"A hybrid evolutionary approach to protein structure prediction with lattice models","publication_year":2011,"publication_date":"2011-06-01","ids":{"openalex":"https://openalex.org/W2168843981","doi":"https://doi.org/10.1109/cec.2011.5949901","mag":"2168843981"},"language":"en","primary_location":{"id":"doi:10.1109/cec.2011.5949901","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cec.2011.5949901","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE Congress of Evolutionary Computation (CEC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009798916","display_name":"Camelia Chira","orcid":"https://orcid.org/0000-0002-1949-1298"},"institutions":[{"id":"https://openalex.org/I3125347698","display_name":"Babe\u0219-Bolyai University","ror":"https://ror.org/02rmd1t30","country_code":"RO","type":"education","lineage":["https://openalex.org/I3125347698"]}],"countries":["RO"],"is_corresponding":true,"raw_author_name":"Camelia Chira","raw_affiliation_strings":["Department of Computer Science, Babes Bolyai University, Cluj-Napoca, Romania"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Babes Bolyai University, Cluj-Napoca, Romania","institution_ids":["https://openalex.org/I3125347698"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5009798916"],"corresponding_institution_ids":["https://openalex.org/I3125347698"],"apc_list":null,"apc_paid":null,"fwci":1.1726,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.78070952,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"2300","last_page":"2306"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crossover","display_name":"Crossover","score":0.806689977645874},{"id":"https://openalex.org/keywords/lattice-protein","display_name":"Lattice protein","score":0.7523441314697266},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"Protein structure prediction","score":0.6109541058540344},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5560968518257141},{"id":"https://openalex.org/keywords/lattice","display_name":"Lattice (music)","score":0.5486956834793091},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5245257019996643},{"id":"https://openalex.org/keywords/genetic-algorithm","display_name":"Genetic algorithm","score":0.5128267407417297},{"id":"https://openalex.org/keywords/hill-climbing","display_name":"Hill climbing","score":0.4865323603153229},{"id":"https://openalex.org/keywords/evolutionary-algorithm","display_name":"Evolutionary algorithm","score":0.4684237241744995},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.44829559326171875},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4299890995025635},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.34269699454307556},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.34062570333480835},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.26899415254592896},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.21427366137504578},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1076284646987915},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.09315428137779236}],"concepts":[{"id":"https://openalex.org/C122507166","wikidata":"https://www.wikidata.org/wiki/Q628906","display_name":"Crossover","level":2,"score":0.806689977645874},{"id":"https://openalex.org/C32598905","wikidata":"https://www.wikidata.org/wiki/Q6497130","display_name":"Lattice protein","level":3,"score":0.7523441314697266},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.6109541058540344},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5560968518257141},{"id":"https://openalex.org/C2781204021","wikidata":"https://www.wikidata.org/wiki/Q6497091","display_name":"Lattice (music)","level":2,"score":0.5486956834793091},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5245257019996643},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.5128267407417297},{"id":"https://openalex.org/C135450995","wikidata":"https://www.wikidata.org/wiki/Q820272","display_name":"Hill climbing","level":2,"score":0.4865323603153229},{"id":"https://openalex.org/C159149176","wikidata":"https://www.wikidata.org/wiki/Q14489129","display_name":"Evolutionary algorithm","level":2,"score":0.4684237241744995},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.44829559326171875},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4299890995025635},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.34269699454307556},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.34062570333480835},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.26899415254592896},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.21427366137504578},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1076284646987915},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09315428137779236},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cec.2011.5949901","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cec.2011.5949901","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE Congress of Evolutionary Computation (CEC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1481729573","https://openalex.org/W1537599249","https://openalex.org/W1592391206","https://openalex.org/W1976869909","https://openalex.org/W2012109362","https://openalex.org/W2013842855","https://openalex.org/W2026980998","https://openalex.org/W2079087579","https://openalex.org/W2080382112","https://openalex.org/W2100356383","https://openalex.org/W2101206889","https://openalex.org/W2110325328","https://openalex.org/W2145387267","https://openalex.org/W2148387177","https://openalex.org/W2154811699","https://openalex.org/W2176003014","https://openalex.org/W2330766527","https://openalex.org/W4299535408","https://openalex.org/W6628780316","https://openalex.org/W6844282875"],"related_works":["https://openalex.org/W1985939653","https://openalex.org/W3125336740","https://openalex.org/W1606499289","https://openalex.org/W2741252017","https://openalex.org/W2911578165","https://openalex.org/W2626282817","https://openalex.org/W200248288","https://openalex.org/W2344044609","https://openalex.org/W1787433968","https://openalex.org/W114187950"],"abstract_inverted_index":{"The":[0,62,115],"prediction":[1],"of":[2,10,54,65,75,85,92],"minimum-energy":[3],"protein":[4,22,94],"structures":[5],"starting":[6],"from":[7,105],"a":[8,14,51,71],"sequence":[9],"amino":[11],"acids":[12],"is":[13,28],"computationally":[15],"challenging":[16],"problem":[17],"even":[18],"in":[19,32,46],"simplified":[20],"lattice":[21,106],"models.":[23],"A":[24],"hybrid":[25],"evolutionary":[26],"model":[27,110,113],"designed":[29],"and":[30,50,78,82,111],"tested":[31],"the":[33,47,59,66,83,90,93],"current":[34],"paper":[35],"to":[36,70],"address":[37],"this":[38],"well-known":[39],"NP-hard":[40],"problem.":[41],"Hill-climbing":[42],"strategies":[43],"are":[44,98,117],"integrated":[45],"search":[48],"operators":[49],"meaningful":[52],"diversification":[53],"genetic":[55,86],"material":[56,87],"occurs":[57],"during":[58],"population":[60],"evolution.":[61],"main":[63],"features":[64],"proposed":[67],"algorithm":[68],"refer":[69],"weak":[72],"hill-climbing":[73],"application":[74],"uniform":[76],"crossover":[77],"pull":[79],"move":[80],"transformations":[81],"randomization":[84],"based":[88],"on":[89],"fingerprint":[91],"conformations.":[95],"Numerical":[96],"experiments":[97],"performed":[99],"for":[100],"several":[101],"difficult":[102],"bidimensional":[103],"instances":[104],"models":[107],"(the":[108],"hydrophobic-polar":[109],"functional":[112],"proteins).":[114],"results":[116],"competitive":[118],"with":[119],"those":[120],"obtained":[121],"by":[122],"related":[123],"population-based":[124],"optimization":[125],"algorithms.":[126]},"counts_by_year":[{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":5}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}