{"id":"https://openalex.org/W1999203705","doi":"https://doi.org/10.1109/cec.2005.1554694","title":"Comparing Evolutionary Optimization with Ant Colony Optimization of Drug Design Interval Rules with and without Pre-Initialization","display_name":"Comparing Evolutionary Optimization with Ant Colony Optimization of Drug Design Interval Rules with and without Pre-Initialization","publication_year":2005,"publication_date":"2005-12-13","ids":{"openalex":"https://openalex.org/W1999203705","doi":"https://doi.org/10.1109/cec.2005.1554694","mag":"1999203705"},"language":"en","primary_location":{"id":"doi:10.1109/cec.2005.1554694","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cec.2005.1554694","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2005 IEEE Congress on Evolutionary Computation","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113930837","display_name":"J\u00fcrgen Paetz","orcid":null},"institutions":[{"id":"https://openalex.org/I5237613","display_name":"Frankfurt University of Applied Sciences","ror":"https://ror.org/02r625m11","country_code":"DE","type":"education","lineage":["https://openalex.org/I5237613"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"J. Paetz","raw_affiliation_strings":["Department of Chemical and Pharmaceutical Sciences, Frankfurt, Germany","Dept. of Chem. & Pharm. Sci., Frankfurt Univ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Pharmaceutical Sciences, Frankfurt, Germany","institution_ids":[]},{"raw_affiliation_string":"Dept. of Chem. & Pharm. Sci., Frankfurt Univ","institution_ids":["https://openalex.org/I5237613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5113930837"],"corresponding_institution_ids":["https://openalex.org/I5237613"],"apc_list":null,"apc_paid":null,"fwci":0.2465,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.5088256,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"1","issue":null,"first_page":"267","last_page":"273"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10820","display_name":"Fuzzy Logic and Control Systems","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10820","display_name":"Fuzzy Logic and Control Systems","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10320","display_name":"Neural Networks and Applications","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11975","display_name":"Evolutionary Algorithms and Applications","score":0.9879000186920166,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/initialization","display_name":"Initialization","score":0.9410529136657715},{"id":"https://openalex.org/keywords/interval","display_name":"Interval (graph theory)","score":0.7474197745323181},{"id":"https://openalex.org/keywords/ant-colony-optimization-algorithms","display_name":"Ant colony optimization algorithms","score":0.6876984238624573},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6306124925613403},{"id":"https://openalex.org/keywords/evolutionary-algorithm","display_name":"Evolutionary algorithm","score":0.5711255073547363},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5187168717384338},{"id":"https://openalex.org/keywords/fuzzy-logic","display_name":"Fuzzy logic","score":0.5004251003265381},{"id":"https://openalex.org/keywords/ant-colony","display_name":"Ant colony","score":0.47973600029945374},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.46484488248825073},{"id":"https://openalex.org/keywords/fuzzy-set","display_name":"Fuzzy set","score":0.441520631313324},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2807806134223938}],"concepts":[{"id":"https://openalex.org/C114466953","wikidata":"https://www.wikidata.org/wiki/Q6034165","display_name":"Initialization","level":2,"score":0.9410529136657715},{"id":"https://openalex.org/C2778067643","wikidata":"https://www.wikidata.org/wiki/Q166507","display_name":"Interval (graph theory)","level":2,"score":0.7474197745323181},{"id":"https://openalex.org/C40128228","wikidata":"https://www.wikidata.org/wiki/Q460851","display_name":"Ant colony optimization algorithms","level":2,"score":0.6876984238624573},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6306124925613403},{"id":"https://openalex.org/C159149176","wikidata":"https://www.wikidata.org/wiki/Q14489129","display_name":"Evolutionary algorithm","level":2,"score":0.5711255073547363},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5187168717384338},{"id":"https://openalex.org/C58166","wikidata":"https://www.wikidata.org/wiki/Q224821","display_name":"Fuzzy logic","level":2,"score":0.5004251003265381},{"id":"https://openalex.org/C60891933","wikidata":"https://www.wikidata.org/wiki/Q796575","display_name":"Ant colony","level":3,"score":0.47973600029945374},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.46484488248825073},{"id":"https://openalex.org/C42011625","wikidata":"https://www.wikidata.org/wiki/Q1055058","display_name":"Fuzzy set","level":3,"score":0.441520631313324},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2807806134223938},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cec.2005.1554694","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cec.2005.1554694","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2005 IEEE Congress on Evolutionary Computation","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6700000166893005,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W22886512","https://openalex.org/W1484413656","https://openalex.org/W1540350410","https://openalex.org/W1545231783","https://openalex.org/W1549439022","https://openalex.org/W1573676079","https://openalex.org/W1602589614","https://openalex.org/W1969837365","https://openalex.org/W2001072463","https://openalex.org/W2001284100","https://openalex.org/W2031372687","https://openalex.org/W2047509756","https://openalex.org/W2091676331","https://openalex.org/W2097460058","https://openalex.org/W2107941094","https://openalex.org/W2111103995","https://openalex.org/W2118648876","https://openalex.org/W2119571185","https://openalex.org/W2121535052","https://openalex.org/W2125965138","https://openalex.org/W2139538108","https://openalex.org/W2140010698","https://openalex.org/W2156477027","https://openalex.org/W2157688326","https://openalex.org/W2159111290","https://openalex.org/W2399934975","https://openalex.org/W2486095760","https://openalex.org/W6628750762","https://openalex.org/W6631638067","https://openalex.org/W6676485907"],"related_works":["https://openalex.org/W2347951034","https://openalex.org/W2313077844","https://openalex.org/W2388326823","https://openalex.org/W2366876790","https://openalex.org/W2071981049","https://openalex.org/W2381829748","https://openalex.org/W2244460820","https://openalex.org/W2109336245","https://openalex.org/W2061313076","https://openalex.org/W2070079705"],"abstract_inverted_index":{"Many":[0],"applications":[1],"deal":[2],"with":[3,137],"knowledge":[4],"in":[5,82,110],"the":[6,15,27,37,40,74,111,141,156],"form":[7],"of":[8,18,29,39,67,70,76,114,144],"'if-then":[9],"rules'.":[10],"In":[11,60],"numerical":[12],"data":[13],"spaces":[14],"condition":[16],"part":[17],"such":[19,89],"rules":[20,44,72,90,109],"is":[21,135,152],"often":[22],"based":[23],"on":[24],"intervals":[25],"where":[26],"values":[28],"single":[30],"variables":[31],"are":[32],"allowed":[33],"to":[34,101,120],"be":[35,46,54,92,118],"within":[36],"ranges":[38],"intervals.":[41],"The":[42,147],"interval":[43,77,108,145],"can":[45,53,91,117],"interpreted":[47],"geometrically":[48],"as":[49,123],"hyper":[50],"rectangles.":[51],"They":[52],"derived":[55],"heuristically":[56],"by":[57,94,97],"adaptive":[58],"learning.":[59],"a":[61,102,127],"previous":[62],"approach":[63],"we":[64,86],"used":[65],"cuts":[66],"membership":[68],"functions":[69],"neuro-fuzzy":[71,142],"for":[73,155],"pre-initialization":[75,143,151],"rules,":[78],"that":[79,150],"were":[80],"reduced":[81],"their":[83],"dimensions.":[84],"As":[85],"showed":[87],"before,":[88],"optimized":[93,119],"evolutionary":[95,130,157],"or":[96],"ant":[98,132],"colony":[99,133],"algorithms":[100],"problem-specific":[103],"criterion.":[104],"We":[105],"demonstrate":[106],"how":[107],"chemical":[112],"area":[113],"virtual":[115],"screening":[116],"characterize":[121],"molecules":[122],"novel":[124],"drugs.":[125],"Mainly,":[126],"comparison":[128],"between":[129],"and":[131,138],"optimization":[134,158],"given,":[136],"without":[139],"using":[140],"borders.":[146],"results":[148],"show":[149],"more":[153],"useful":[154],"paradigm":[159]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}