{"id":"https://openalex.org/W2972709016","doi":"https://doi.org/10.1109/cdc40024.2019.9030049","title":"Qualitative behavior and robustness of dendritic trafficking","display_name":"Qualitative behavior and robustness of dendritic trafficking","publication_year":2019,"publication_date":"2019-12-01","ids":{"openalex":"https://openalex.org/W2972709016","doi":"https://doi.org/10.1109/cdc40024.2019.9030049","mag":"2972709016"},"language":"en","primary_location":{"id":"doi:10.1109/cdc40024.2019.9030049","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cdc40024.2019.9030049","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 58th Conference on Decision and Control (CDC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["arxiv","crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/1909.05778","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087374355","display_name":"Saeed Aljaberi","orcid":null},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Saeed Aljaberi","raw_affiliation_strings":["Department of Engineering, University of Cambridge, UK","Univ. of Cambridge"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Engineering, University of Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Univ. of Cambridge","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044317847","display_name":"Timothy O\u2019Leary","orcid":"https://orcid.org/0000-0002-1029-0158"},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Timothy O'Leary","raw_affiliation_strings":["Univ. of Cambridge"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Univ. of Cambridge","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034730197","display_name":"Fulvio Forni","orcid":"https://orcid.org/0000-0002-5728-0176"},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Fulvio Forni","raw_affiliation_strings":["Department of Engineering, University of Cambridge, UK","Univ. of Cambridge"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Engineering, University of Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Univ. of Cambridge","institution_ids":["https://openalex.org/I241749"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I241749"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"6628","last_page":"6633"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.8191937804222107},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.7139022350311279},{"id":"https://openalex.org/keywords/closed-loop","display_name":"Closed loop","score":0.6075769662857056},{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.5722799897193909},{"id":"https://openalex.org/keywords/dominance","display_name":"Dominance (genetics)","score":0.43184250593185425},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.40354230999946594},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3927197754383087},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.3379247784614563},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2813238501548767},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.25315988063812256},{"id":"https://openalex.org/keywords/control-engineering","display_name":"Control engineering","score":0.2306278944015503},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.22068849205970764},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.19279494881629944},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15855863690376282},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.08373522758483887}],"concepts":[{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.8191937804222107},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.7139022350311279},{"id":"https://openalex.org/C3019251811","wikidata":"https://www.wikidata.org/wiki/Q5135346","display_name":"Closed loop","level":2,"score":0.6075769662857056},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.5722799897193909},{"id":"https://openalex.org/C151913843","wikidata":"https://www.wikidata.org/wiki/Q3454555","display_name":"Dominance (genetics)","level":3,"score":0.43184250593185425},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.40354230999946594},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3927197754383087},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3379247784614563},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2813238501548767},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.25315988063812256},{"id":"https://openalex.org/C133731056","wikidata":"https://www.wikidata.org/wiki/Q4917288","display_name":"Control engineering","level":1,"score":0.2306278944015503},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.22068849205970764},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.19279494881629944},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15855863690376282},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.08373522758483887},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1109/cdc40024.2019.9030049","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cdc40024.2019.9030049","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 58th Conference on Decision and Control (CDC)","raw_type":"proceedings-article"},{"id":"pmh:oai:arXiv.org:1909.05778","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1909.05778","pdf_url":"https://arxiv.org/pdf/1909.05778","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/388371","is_oa":true,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/388371","pdf_url":"https://www.repository.cam.ac.uk/bitstreams/95b5be98-bbd3-447e-a2df-529f48a7e144/download","source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Conference Object"},{"id":"mag:2972709016","is_oa":true,"landing_page_url":"http://arxiv.org/pdf/1909.05778.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"arXiv (Cornell University)","raw_type":null},{"id":"pmh:oai:generic.eprints.org:1122593","is_oa":false,"landing_page_url":"http://publications.eng.cam.ac.uk/1122593/","pdf_url":null,"source":{"id":"https://openalex.org/S4406922847","display_name":"Cambridge University Engineering Department Publications Database","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Conference or Workshop Item"},{"id":"doi:10.48550/arxiv.1909.05778","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.1909.05778","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"Preprint"},{"id":"doi:10.17863/cam.120765","is_oa":true,"landing_page_url":"https://doi.org/10.17863/cam.120765","pdf_url":null,"source":{"id":"https://openalex.org/S7407050737","display_name":"Apollo","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"Other"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:1909.05778","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1909.05778","pdf_url":"https://arxiv.org/pdf/1909.05778","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2972709016.pdf","grobid_xml":"https://content.openalex.org/works/W2972709016.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1600015713","https://openalex.org/W1800303662","https://openalex.org/W1835291487","https://openalex.org/W1905544381","https://openalex.org/W1959450586","https://openalex.org/W1967020613","https://openalex.org/W1967940818","https://openalex.org/W1973517385","https://openalex.org/W1976515682","https://openalex.org/W2006155705","https://openalex.org/W2012852881","https://openalex.org/W2026769037","https://openalex.org/W2059668389","https://openalex.org/W2078108567","https://openalex.org/W2308801312","https://openalex.org/W2521801405","https://openalex.org/W2752756088","https://openalex.org/W2962839651","https://openalex.org/W2962965869","https://openalex.org/W3195133498","https://openalex.org/W3210839039"],"related_works":["https://openalex.org/W3012018885","https://openalex.org/W2509256428","https://openalex.org/W2101567418","https://openalex.org/W1967492427","https://openalex.org/W3185553914","https://openalex.org/W2003283302","https://openalex.org/W3142294119","https://openalex.org/W1948323557","https://openalex.org/W2128809445","https://openalex.org/W2784221522","https://openalex.org/W2183292775","https://openalex.org/W2293154344","https://openalex.org/W1990121351","https://openalex.org/W2035894715","https://openalex.org/W2766310506","https://openalex.org/W1986403376","https://openalex.org/W2788684126","https://openalex.org/W2063177229","https://openalex.org/W1267855475","https://openalex.org/W2601830013"],"abstract_inverted_index":{"The":[0],"paper":[1],"studies":[2],"homeostatic":[3],"ion":[4,77],"channel":[5,21,78],"trafficking":[6],"in":[7],"neurons.":[8],"We":[9,30,50],"derive":[10],"a":[11],"nonlinear":[12],"closed-loop":[13],"model":[14,33],"that":[15],"captures":[16],"active":[17],"transport":[18],"with":[19,76],"degradation,":[20],"insertion,":[22],"average":[23],"membrane":[24],"potential":[25],"activity,":[26],"and":[27,37,64],"integral":[28],"control.":[29],"study":[31],"the":[32,55,58],"via":[34],"dominance":[35],"theory":[36],"differential":[38],"dissipativity":[39],"to":[40,47,62,70],"show":[41],"when":[42],"steady":[43],"regulation":[44],"gives":[45],"way":[46],"pathological":[48],"oscillations.":[49],"provide":[51],"quantitative":[52],"results":[53],"on":[54],"robustness":[56],"of":[57],"closed":[59],"loop":[60],"behavior":[61],"static":[63],"dynamic":[65],"uncertainties,":[66],"which":[67],"allows":[68],"us":[69],"understand":[71],"how":[72],"cell":[73],"growth":[74],"interacts":[75],"regulation.":[79]},"counts_by_year":[],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}