{"id":"https://openalex.org/W3011517172","doi":"https://doi.org/10.1109/cdc40024.2019.9029374","title":"Rapid Circadian Entrainment in Models of Circadian Genes Regulation","display_name":"Rapid Circadian Entrainment in Models of Circadian Genes Regulation","publication_year":2019,"publication_date":"2019-12-01","ids":{"openalex":"https://openalex.org/W3011517172","doi":"https://doi.org/10.1109/cdc40024.2019.9029374","mag":"3011517172"},"language":"en","primary_location":{"id":"doi:10.1109/cdc40024.2019.9029374","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cdc40024.2019.9029374","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 58th Conference on Decision and Control (CDC)","raw_type":"proceedings-article"},"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009238156","display_name":"Jiawei Yin","orcid":"https://orcid.org/0000-0003-4227-3448"},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jiawei Yin","raw_affiliation_strings":["Engineering Research Center, Rensselaer Polytechnic Institute, Light Enabled Systems and Application (LESA), Troy, NY, USA"],"affiliations":[{"raw_affiliation_string":"Engineering Research Center, Rensselaer Polytechnic Institute, Light Enabled Systems and Application (LESA), Troy, NY, USA","institution_ids":["https://openalex.org/I165799507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029921181","display_name":"A. Agung Julius","orcid":"https://orcid.org/0000-0002-0970-3226"},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Agung Julius","raw_affiliation_strings":["Engineering Research Center, Rensselaer Polytechnic Institute, Light Enabled Systems and Application (LESA), Troy, NY, USA"],"affiliations":[{"raw_affiliation_string":"Engineering Research Center, Rensselaer Polytechnic Institute, Light Enabled Systems and Application (LESA), Troy, NY, USA","institution_ids":["https://openalex.org/I165799507"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074830403","display_name":"John T. Wen","orcid":"https://orcid.org/0000-0002-5123-5411"},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John T. Wen","raw_affiliation_strings":["Engineering Research Center, Rensselaer Polytechnic Institute, Light Enabled Systems and Application (LESA), Troy, NY, USA"],"affiliations":[{"raw_affiliation_string":"Engineering Research Center, Rensselaer Polytechnic Institute, Light Enabled Systems and Application (LESA), Troy, NY, USA","institution_ids":["https://openalex.org/I165799507"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5009238156"],"corresponding_institution_ids":["https://openalex.org/I165799507"],"apc_list":null,"apc_paid":null,"fwci":0.1290098,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.43370166,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1899","last_page":"1906"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology","score":0.9466000199317932,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/entrainment","display_name":"Entrainment (biomusicology)","score":0.9041613340377808},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"Circadian rhythm","score":0.8975310325622559},{"id":"https://openalex.org/keywords/bacterial-circadian-rhythms","display_name":"Bacterial circadian rhythms","score":0.4822481572628021},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4382113218307495},{"id":"https://openalex.org/keywords/circadian-clock","display_name":"Circadian clock","score":0.43638747930526733},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3207780718803406},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.20181488990783691},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1625884771347046},{"id":"https://openalex.org/keywords/rhythm","display_name":"Rhythm","score":0.1215493381023407}],"concepts":[{"id":"https://openalex.org/C139992725","wikidata":"https://www.wikidata.org/wiki/Q5380656","display_name":"Entrainment (biomusicology)","level":3,"score":0.9041613340377808},{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.8975310325622559},{"id":"https://openalex.org/C130679736","wikidata":"https://www.wikidata.org/wiki/Q3454009","display_name":"Bacterial circadian rhythms","level":4,"score":0.4822481572628021},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4382113218307495},{"id":"https://openalex.org/C38606739","wikidata":"https://www.wikidata.org/wiki/Q5121352","display_name":"Circadian clock","level":3,"score":0.43638747930526733},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3207780718803406},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20181488990783691},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1625884771347046},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.1215493381023407}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cdc40024.2019.9029374","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cdc40024.2019.9029374","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE 58th Conference on Decision and Control (CDC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1966696063","https://openalex.org/W1980723855","https://openalex.org/W1995042086","https://openalex.org/W2017428033","https://openalex.org/W2041845062","https://openalex.org/W2042068133","https://openalex.org/W2047279254","https://openalex.org/W2053325028","https://openalex.org/W2074539768","https://openalex.org/W2075396624","https://openalex.org/W2114790553","https://openalex.org/W2115688366","https://openalex.org/W2118809524","https://openalex.org/W2130618526","https://openalex.org/W2139376449","https://openalex.org/W2147330097","https://openalex.org/W2342367527","https://openalex.org/W2475465861","https://openalex.org/W2783747045","https://openalex.org/W2798500587","https://openalex.org/W2996037132","https://openalex.org/W4230646845","https://openalex.org/W6771931473"],"related_works":["https://openalex.org/W2587929016","https://openalex.org/W2016153726","https://openalex.org/W1981959626","https://openalex.org/W2053379810","https://openalex.org/W2137189205","https://openalex.org/W2050701942","https://openalex.org/W2279228672","https://openalex.org/W4251219350","https://openalex.org/W3065977955","https://openalex.org/W1995495057"],"abstract_inverted_index":{"The":[0,52],"light-based":[1],"minimum-time":[2,116,127],"circadian":[3,20,131],"entrainment":[4],"problem":[5,119],"for":[6,62,113],"mammals,":[7],"Neurospora,":[8],"and":[9,46,55,94,134],"Drosophila":[10],"is":[11],"studied":[12],"based":[13],"on":[14,82,120,130],"the":[15,41,47,64,69,73,76,83,88,92,95,100,115,124],"mathematical":[16],"models":[17,24],"of":[18,75,91,126],"their":[19],"gene":[21,132],"regulation.":[22],"These":[23],"contain":[25],"high":[26],"order":[27],"nonlinear":[28],"differential":[29],"equations.":[30],"Two":[31],"model":[32,97],"simplification":[33],"methods":[34],"are":[35,60],"applied":[36,61],"to":[37,98],"these":[38],"high-order":[39,70],"models:":[40],"phase":[42],"response":[43],"curves":[44],"(PRC)":[45],"Principal":[48],"Orthogonal":[49],"Decomposition":[50],"(POD).":[51],"variational":[53],"calculus":[54],"a":[56,110],"gradient":[57,77,101],"descent":[58,78,102],"algorithm":[59,79],"solving":[63,114],"optimal":[65,89,117,128],"light":[66,129],"input":[67],"in":[68],"models.":[71],"As":[72],"results":[74],"rely":[80],"heavily":[81],"initial":[84],"guesses,":[85],"we":[86,107],"use":[87],"control":[90,118],"PRC":[93],"simplified":[96],"initialize":[99],"algorithm.":[103],"In":[104],"this":[105],"paper,":[106],"present:":[108],"(1)":[109],"general":[111],"process":[112],"highorder":[121],"models;":[122],"(2)":[123],"impacts":[125],"transcription":[133],"protein":[135],"synthesis.":[136]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}