{"id":"https://openalex.org/W2156886033","doi":"https://doi.org/10.1109/cdc.2007.4434844","title":"Control to concentrate drug-coated magnetic particles to deep-tissue tumors for targeted cancer chemotherapy","display_name":"Control to concentrate drug-coated magnetic particles to deep-tissue tumors for targeted cancer chemotherapy","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W2156886033","doi":"https://doi.org/10.1109/cdc.2007.4434844","mag":"2156886033"},"language":"en","primary_location":{"id":"doi:10.1109/cdc.2007.4434844","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cdc.2007.4434844","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 46th IEEE Conference on Decision and Control","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053511461","display_name":"D. A. Diver","orcid":"https://orcid.org/0000-0001-6478-6020"},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Declan A. Diver","raw_affiliation_strings":["Department of Physics and Astronomy, University of Glasgow, UK"],"affiliations":[{"raw_affiliation_string":"Department of Physics and Astronomy, University of Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111592515","display_name":"Andreas S. L\u00fcbbe","orcid":null},"institutions":[{"id":"https://openalex.org/I170828890","display_name":"Centro de Estudios e Investigaciones T\u00e9cnicas de Gipuzkoa","ror":"https://ror.org/022wqqf69","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I170828890"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Andreas S. Lubbe","raw_affiliation_strings":["CEIT, San Sabastian, Spain"],"affiliations":[{"raw_affiliation_string":"CEIT, San Sabastian, Spain","institution_ids":["https://openalex.org/I170828890"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5053511461"],"corresponding_institution_ids":["https://openalex.org/I7882870"],"apc_list":null,"apc_paid":null,"fwci":2.0891,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.86941168,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"3901","last_page":"3906"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12405","display_name":"Characterization and Applications of Magnetic Nanoparticles","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12405","display_name":"Characterization and Applications of Magnetic Nanoparticles","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemotherapy","display_name":"Chemotherapy","score":0.5982638001441956},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.5964652895927429},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.5448664426803589},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"Targeted drug delivery","score":0.4927871525287628},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4525316655635834},{"id":"https://openalex.org/keywords/magnetic-nanoparticles","display_name":"Magnetic nanoparticles","score":0.42940765619277954},{"id":"https://openalex.org/keywords/cancer-chemotherapy","display_name":"Cancer chemotherapy","score":0.4158307611942291},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.35808929800987244},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.35078638792037964},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.2533028721809387},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.2423383593559265},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.1908724308013916},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.15075626969337463},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.11581882834434509}],"concepts":[{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5982638001441956},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5964652895927429},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5448664426803589},{"id":"https://openalex.org/C126511603","wikidata":"https://www.wikidata.org/wiki/Q1261145","display_name":"Targeted drug delivery","level":3,"score":0.4927871525287628},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4525316655635834},{"id":"https://openalex.org/C87023908","wikidata":"https://www.wikidata.org/wiki/Q3870166","display_name":"Magnetic nanoparticles","level":3,"score":0.42940765619277954},{"id":"https://openalex.org/C2983288658","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Cancer chemotherapy","level":3,"score":0.4158307611942291},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.35808929800987244},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35078638792037964},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.2533028721809387},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2423383593559265},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1908724308013916},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.15075626969337463},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.11581882834434509}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/cdc.2007.4434844","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cdc.2007.4434844","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 46th IEEE Conference on Decision and Control","raw_type":"proceedings-article"},{"id":"pmh:oai:eprints.gla.ac.uk:89434","is_oa":false,"landing_page_url":"http://eprints.gla.ac.uk/89434/","pdf_url":null,"source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":false,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W374497283","https://openalex.org/W1496281810","https://openalex.org/W1513925740","https://openalex.org/W1579902817","https://openalex.org/W1865814132","https://openalex.org/W1991443010","https://openalex.org/W1993706573","https://openalex.org/W2012213050","https://openalex.org/W2042868684","https://openalex.org/W2044792982","https://openalex.org/W2049020837","https://openalex.org/W2061341117","https://openalex.org/W2064438622","https://openalex.org/W2087827184","https://openalex.org/W2100348500","https://openalex.org/W2104662939","https://openalex.org/W2123849267","https://openalex.org/W2989910212","https://openalex.org/W3021509614","https://openalex.org/W4254056711","https://openalex.org/W4255378812","https://openalex.org/W6629779683","https://openalex.org/W6769632136"],"related_works":["https://openalex.org/W4206379684","https://openalex.org/W2018282398","https://openalex.org/W2182734686","https://openalex.org/W2375178259","https://openalex.org/W2413405428","https://openalex.org/W2479370733","https://openalex.org/W3049622765","https://openalex.org/W2040360558","https://openalex.org/W1987121317","https://openalex.org/W2988003305"],"abstract_inverted_index":{"The":[0],"control":[1,18,71,116,142,179],"problem":[2,117,121],"for":[3,131,151,192],"concentrating":[4],"drug-coated":[5],"magnetic":[6,33,73,133,144],"nano-particles":[7,45],"to":[8,46,53,79,135,184,188],"deep-tissue":[9],"tumors":[10,54,63,80,191],"in":[11,67,82,97,138,172],"a":[12,125,136,148,173],"patient":[13],"is":[14,123],"developed":[15],"and":[16,49,106,146,161,181],"initial":[17,129],"ideas":[19],"are":[20,35,168],"presented.":[21],"In":[22],"current":[23],"implementations":[24],"of":[25,72,100,143,178,196],"magnetically-controlled":[26],"drug":[27,77,87],"targeting,":[28],"stationary":[29],"magnets":[30,42],"(creating":[31],"static":[32],"fields)":[34],"held":[36],"outside":[37],"the":[38,44,58,83,90,98,101,115,120,153,156,162,176],"patient\u2019s":[39],"body,":[40,84],"these":[41],"attract":[43],"their":[47],"corners,":[48],"hence":[50],"focus":[51],"them":[52],"at":[55,89],"or":[56],"near":[57],"skin":[59],"surface.":[60],"Deep":[61],"tissue":[62,190],"cannot":[64],"be":[65],"targeted":[66],"this":[68],"way.":[69],"Dynamic":[70],"fields":[74],"can":[75],"allow":[76],"targeting":[78],"deep":[81,189],"creating":[85],"high":[86],"concentrations":[88,96],"tumor":[91],"(effective":[92],"treatment)":[93],"with":[94],"low":[95],"rest":[99],"body":[102],"(eliminating":[103],"life-threatening":[104],"side-effects),":[105],"thereby":[107],"dramatically":[108,193],"improving":[109],"chemotherapy":[110,186],"treatment.":[111],"Here":[112],"we":[113,167],"synthesize":[114],"(accurately":[118],"stating":[119],"definition":[122],"itself":[124],"serious":[126],"challenge),":[127],"show":[128],"results":[130,171],"focusing":[132],"particles":[134],"target":[137],"air":[139],"by":[140],"feedback":[141],"fields,":[145],"present":[147],"first-cut":[149],"approach":[150],"doing":[152],"same":[154],"inside":[155],"human":[157],"blood":[158],"vasculature":[159],"network":[160],"surrounding":[163],"tissue.":[164],"As":[165],"such,":[166],"presenting":[169],"preliminary":[170],"long-term":[174],"effort.":[175],"development":[177],"algorithms":[180],"sensing/actuating":[182],"technology":[183],"concentrate":[185],"drugs":[187],"improved":[194],"treatment":[195],"cancer.":[197]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2016-06-24T00:00:00"}
