{"id":"https://openalex.org/W2155148112","doi":"https://doi.org/10.1109/ccmb.2013.6609165","title":"A model of stimulus induced epileptic spike-wave discharges","display_name":"A model of stimulus induced epileptic spike-wave discharges","publication_year":2013,"publication_date":"2013-04-01","ids":{"openalex":"https://openalex.org/W2155148112","doi":"https://doi.org/10.1109/ccmb.2013.6609165","mag":"2155148112"},"language":"en","primary_location":{"id":"doi:10.1109/ccmb.2013.6609165","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ccmb.2013.6609165","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE Symposium on Computational Intelligence, Cognitive Algorithms, Mind, and Brain (CCMB)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/1721.1/132157","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020252837","display_name":"Peter N. Taylor","orcid":"https://orcid.org/0000-0003-2144-9838"},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Peter N. Taylor","raw_affiliation_strings":["School of Electrical & Electronic Engineering, Nanyang Technological University, Singapore"],"affiliations":[{"raw_affiliation_string":"School of Electrical & Electronic Engineering, Nanyang Technological University, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024260303","display_name":"Gerold Baier","orcid":"https://orcid.org/0000-0002-2540-3100"},"institutions":[{"id":"https://openalex.org/I223822909","display_name":"Heidelberg University","ror":"https://ror.org/038t36y30","country_code":"DE","type":"education","lineage":["https://openalex.org/I223822909"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gerold Baier","raw_affiliation_strings":["Modelling of Biological Processes, Centre for Organismal Studies, University of Heidelberg, Germany"],"affiliations":[{"raw_affiliation_string":"Modelling of Biological Processes, Centre for Organismal Studies, University of Heidelberg, Germany","institution_ids":["https://openalex.org/I223822909"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031778533","display_name":"Sydney S. Cash","orcid":"https://orcid.org/0000-0002-4557-6391"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sydney S. Cash","raw_affiliation_strings":["Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital, Harvard Medical School, Cambridge, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082613025","display_name":"Justin Dauwels","orcid":"https://orcid.org/0000-0002-4390-1568"},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Justin Dauwels","raw_affiliation_strings":["School of Electrical & Electronic Engineering, Nanyang Technological University, Singapore"],"affiliations":[{"raw_affiliation_string":"School of Electrical & Electronic Engineering, Nanyang Technological University, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044026747","display_name":"Jean-Jacques Slotine","orcid":"https://orcid.org/0000-0002-7161-7812"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean-Jacques Slotine","raw_affiliation_strings":["Department of Mechanical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010837788","display_name":"Yujiang Wang","orcid":"https://orcid.org/0000-0002-4847-6273"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Yujiang Wang","raw_affiliation_strings":["Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5020252837"],"corresponding_institution_ids":["https://openalex.org/I172675005"],"apc_list":null,"apc_paid":null,"fwci":1.7058,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.83926713,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"53","last_page":"59"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.7312325239181519},{"id":"https://openalex.org/keywords/stimulus","display_name":"Stimulus (psychology)","score":0.6013784408569336},{"id":"https://openalex.org/keywords/local-field-potential","display_name":"Local field potential","score":0.5913377404212952},{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.4834095239639282},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.46951454877853394},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44984787702560425},{"id":"https://openalex.org/keywords/cortical-neurons","display_name":"Cortical neurons","score":0.4494952857494354},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.4180680215358734},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.35839712619781494},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.31193244457244873},{"id":"https://openalex.org/keywords/cognitive-psychology","display_name":"Cognitive psychology","score":0.10271283984184265}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7312325239181519},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.6013784408569336},{"id":"https://openalex.org/C117838684","wikidata":"https://www.wikidata.org/wiki/Q533483","display_name":"Local field potential","level":2,"score":0.5913377404212952},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.4834095239639282},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.46951454877853394},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44984787702560425},{"id":"https://openalex.org/C2983650178","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cortical neurons","level":2,"score":0.4494952857494354},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.4180680215358734},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.35839712619781494},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.31193244457244873},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.10271283984184265}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/ccmb.2013.6609165","is_oa":false,"landing_page_url":"https://doi.org/10.1109/ccmb.2013.6609165","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE Symposium on Computational Intelligence, Cognitive Algorithms, Mind, and Brain (CCMB)","raw_type":"proceedings-article"},{"id":"pmh:oai:dspace.mit.edu:1721.1/132157","is_oa":true,"landing_page_url":"https://hdl.handle.net/1721.1/132157","pdf_url":null,"source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Other repository","raw_type":"http://purl.org/eprint/type/ConferencePaper"},{"id":"pmh:oai:dspace.mit.edu:1721.1/132157.2","is_oa":true,"landing_page_url":"https://hdl.handle.net/1721.1/132157.2","pdf_url":null,"source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Other repository","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:dspace.mit.edu:1721.1/132157","is_oa":true,"landing_page_url":"https://hdl.handle.net/1721.1/132157","pdf_url":null,"source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Other repository","raw_type":"http://purl.org/eprint/type/ConferencePaper"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1519673444","https://openalex.org/W1840565448","https://openalex.org/W1874867185","https://openalex.org/W1886118302","https://openalex.org/W1964824984","https://openalex.org/W1968865407","https://openalex.org/W1981140845","https://openalex.org/W2002388289","https://openalex.org/W2008462638","https://openalex.org/W2008518032","https://openalex.org/W2014721375","https://openalex.org/W2016354087","https://openalex.org/W2021281924","https://openalex.org/W2022436691","https://openalex.org/W2029374903","https://openalex.org/W2034931436","https://openalex.org/W2044113523","https://openalex.org/W2052990681","https://openalex.org/W2063962699","https://openalex.org/W2085297965","https://openalex.org/W2101420429","https://openalex.org/W2115726932","https://openalex.org/W2123553271","https://openalex.org/W2127381920","https://openalex.org/W2131582127","https://openalex.org/W2135234927","https://openalex.org/W2147223467","https://openalex.org/W2155438906","https://openalex.org/W2158343591","https://openalex.org/W2160184536","https://openalex.org/W2165861322","https://openalex.org/W2167395832","https://openalex.org/W2170246198","https://openalex.org/W2313560363","https://openalex.org/W2506699060"],"related_works":["https://openalex.org/W1986274952","https://openalex.org/W2151134065","https://openalex.org/W2945442807","https://openalex.org/W4294203951","https://openalex.org/W3205306594","https://openalex.org/W4223461257","https://openalex.org/W2027159176","https://openalex.org/W2012315399","https://openalex.org/W2951735952","https://openalex.org/W2081202972"],"abstract_inverted_index":{"Recent":[0],"clinical":[1],"and":[2,58,100,130,149,173],"experimental":[3,56],"evidence":[4],"suggests":[5],"that":[6,108,135,158],"the":[7,102,122,136,146,150,153,170],"spike-wave":[8],"discharges":[9],"(SWD)":[10],"of":[11,73,110,116,125,152],"absence":[12],"seizures":[13],"result":[14],"from":[15,88],"local":[16],"activity":[17],"within":[18],"a":[19,47,60,89,112,166,175],"hyperexcitable":[20],"cortical":[21,30,80,171],"region":[22],"with":[23,53],"rapid":[24,123],"generalization":[25],"through":[26],"thalamocortical":[27,74,131],"networks.":[28],"The":[29],"focus":[31,172],"is":[32,50],"said":[33],"to":[34,38,45,76,121,184],"react":[35],"more":[36],"strongly":[37],"stimulation":[39,109],"than":[40],"other":[41],"areas.":[42],"We":[43,94,106,133],"seek":[44],"develop":[46],"model":[48,72,98,117,138,156],"which":[49,82],"in":[51,160,178,182,185],"agreement":[52],"these":[54],"recent":[55],"findings":[57],"suggest":[59],"possible":[61,167],"explanation.":[62],"In":[63],"this":[64],"study":[65],"we":[66],"extend":[67],"an":[68],"existing":[69],"neural":[70],"field":[71],"interaction":[75],"account":[77],"for":[78,169,177],"multiple":[79],"regions":[81],"are":[83],"connected":[84],"according":[85],"connectivity":[86,162],"inferred":[87],"clinically":[90],"diagnosed":[91],"epileptic":[92],"patient.":[93],"stimulate":[95],"at":[96],"different":[97],"electrodes":[99,118],"investigate":[101],"resulting":[103,137],"seizure":[104],"duration.":[105],"observe":[107],"only":[111],"small":[113],"subset":[114],"(11%)":[115],"can":[119],"lead":[120],"generalisation":[124],"SWD":[126],"via":[127],"both":[128],"corticocortical":[129,161],"pathways.":[132],"find":[134],"dynamics":[139],"(seizure":[140],"duration)":[141],"varies":[142],"significantly":[143],"dependent":[144],"upon":[145],"nodes":[147],"stimulated":[148],"amplitude":[151],"stimulus.":[154],"Our":[155],"indicates":[157],"heterogeneities":[159],"could":[163],"serve":[164],"as":[165],"reason":[168],"provides":[174],"platform":[176],"silico":[179],"hypothesis":[180,187],"generation":[181],"complement":[183],"vivo":[186],"validation.":[188]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}