{"id":"https://openalex.org/W2121519829","doi":"https://doi.org/10.1109/cbms.2010.6042648","title":"Sensitivity of volumetric brain analysis to systematic and random errors","display_name":"Sensitivity of volumetric brain analysis to systematic and random errors","publication_year":2010,"publication_date":"2010-10-01","ids":{"openalex":"https://openalex.org/W2121519829","doi":"https://doi.org/10.1109/cbms.2010.6042648","mag":"2121519829"},"language":"en","primary_location":{"id":"doi:10.1109/cbms.2010.6042648","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms.2010.6042648","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE 23rd International Symposium on Computer-Based Medical Systems (CBMS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://aaltodoc.aalto.fi/bitstreams/66e2af56-9282-4c77-85ee-1e98b5102d7e/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046189534","display_name":"Antonios-Konstantinos Thanellas","orcid":"https://orcid.org/0000-0003-1422-9087"},"institutions":[{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Antonios-Konstantinos Thanellas","raw_affiliation_strings":["Department of Biomedical Engineering and Computational Science, Aalto University, Aalto, Finland","Aalto University Department of Biomedical Engineering and Computational Science, P.O. Box 12200, FI-00076 AALTO, Finland"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Computational Science, Aalto University, Aalto, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Aalto University Department of Biomedical Engineering and Computational Science, P.O. Box 12200, FI-00076 AALTO, Finland","institution_ids":["https://openalex.org/I9927081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052116042","display_name":"Mika Pollari","orcid":null},"institutions":[{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Mika Pollari","raw_affiliation_strings":["Department of Biomedical Engineering and Computational Science, Aalto University, Aalto, Finland","Aalto University Department of Biomedical Engineering and Computational Science, P.O. Box 12200, FI-00076 AALTO, Finland"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering and Computational Science, Aalto University, Aalto, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Aalto University Department of Biomedical Engineering and Computational Science, P.O. Box 12200, FI-00076 AALTO, Finland","institution_ids":["https://openalex.org/I9927081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5046189534"],"corresponding_institution_ids":["https://openalex.org/I9927081"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.25315486,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"238","last_page":"242"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/confounding","display_name":"Confounding","score":0.838937520980835},{"id":"https://openalex.org/keywords/brain-size","display_name":"Brain size","score":0.5937539339065552},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.5881175398826599},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5200369358062744},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.47939252853393555},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4428635537624359},{"id":"https://openalex.org/keywords/selection-bias","display_name":"Selection bias","score":0.4413529634475708},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.413926362991333},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.29721033573150635},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.17931896448135376},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.08503541350364685},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.07547813653945923}],"concepts":[{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.838937520980835},{"id":"https://openalex.org/C65835030","wikidata":"https://www.wikidata.org/wiki/Q1030681","display_name":"Brain size","level":3,"score":0.5937539339065552},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.5881175398826599},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5200369358062744},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.47939252853393555},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4428635537624359},{"id":"https://openalex.org/C40423286","wikidata":"https://www.wikidata.org/wiki/Q284172","display_name":"Selection bias","level":2,"score":0.4413529634475708},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.413926362991333},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.29721033573150635},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.17931896448135376},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.08503541350364685},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.07547813653945923},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/cbms.2010.6042648","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms.2010.6042648","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE 23rd International Symposium on Computer-Based Medical Systems (CBMS)","raw_type":"proceedings-article"},{"id":"pmh:oai:aaltodoc.aalto.fi:123456789/126856","is_oa":true,"landing_page_url":"https://aaltodoc.aalto.fi/handle/123456789/126856","pdf_url":"https://aaltodoc.aalto.fi/bitstreams/66e2af56-9282-4c77-85ee-1e98b5102d7e/download","source":{"id":"https://openalex.org/S4306401662","display_name":"Aaltodoc (Aalto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I9927081","host_organization_name":"Aalto University","host_organization_lineage":["https://openalex.org/I9927081"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"V\u00e4it\u00f6skirja (artikkeli)"}],"best_oa_location":{"id":"pmh:oai:aaltodoc.aalto.fi:123456789/126856","is_oa":true,"landing_page_url":"https://aaltodoc.aalto.fi/handle/123456789/126856","pdf_url":"https://aaltodoc.aalto.fi/bitstreams/66e2af56-9282-4c77-85ee-1e98b5102d7e/download","source":{"id":"https://openalex.org/S4306401662","display_name":"Aaltodoc (Aalto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I9927081","host_organization_name":"Aalto University","host_organization_lineage":["https://openalex.org/I9927081"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"V\u00e4it\u00f6skirja (artikkeli)"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2121519829.pdf"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W2006096283","https://openalex.org/W2009739635","https://openalex.org/W2028942474","https://openalex.org/W2029771096","https://openalex.org/W2031224239","https://openalex.org/W2032433220","https://openalex.org/W2067140282","https://openalex.org/W2078524519","https://openalex.org/W2095901107","https://openalex.org/W2149376688","https://openalex.org/W2152839913","https://openalex.org/W2161207117","https://openalex.org/W2169928804","https://openalex.org/W2171528993"],"related_works":["https://openalex.org/W3086603641","https://openalex.org/W2196308895","https://openalex.org/W1964352452","https://openalex.org/W2996713848","https://openalex.org/W2616820708","https://openalex.org/W4256092668","https://openalex.org/W2409888260","https://openalex.org/W1992882281","https://openalex.org/W2268836774","https://openalex.org/W4389623796"],"abstract_inverted_index":{"Brain":[0],"structures":[1],"are":[2,39,55,100],"subjected":[3],"to":[4,23,41,83,127,143],"changes":[5],"caused":[6],"by":[7],"genetic,":[8],"environmental":[9],"factors":[10,98],"or":[11],"disease":[12],"and":[13,57,76,95,120,133],"gender,":[14],"age":[15],"related":[16],"reasons.":[17],"Different":[18],"methods":[19,106],"have":[20,60],"been":[21,61],"developed":[22],"capture":[24],"these":[25],"changes,":[26],"but":[27,66],"their":[28],"agreement":[29],"over":[30],"the":[31,42,46,73,90,108,111,145],"same":[32],"data":[33],"may":[34],"significantly":[35],"vary.":[36],"These":[37],"variations":[38],"attributed":[40],"methodological":[43],"differences":[44,130],"of":[45,92,110],"employed":[47],"methods.":[48],"Popular":[49],"tools":[50],"for":[51],"measuring":[52],"brain":[53,118,121],"atrophy":[54],"SIENA":[56],"SIENAX":[58],"that":[59,78,99,116],"compared":[62],"in":[63,102,136,152],"previous":[64],"studies":[65],"no":[67],"work":[68,88],"has":[69],"carefully":[70],"weeded":[71],"out":[72],"possible":[74,142],"bias":[75],"confounding":[77,94],"can":[79,124,149],"be":[80,125,150],"easily":[81],"introduced":[82,151],"such":[84],"analyses.":[85],"The":[86],"present":[87],"tackles":[89],"problem":[91],"bias,":[93],"random":[96],"variation":[97],"inserted":[101],"any":[103,153],"volumetric":[104],"analysis":[105],"from":[107],"selection":[109],"input":[112],"data.":[113],"Evidence":[114],"showed":[115],"normalized":[117],"volume":[119,122],"change":[123],"used":[126],"characterize":[128],"group":[129],"between":[131],"healthy":[132],"non-healthy":[134],"subjects":[135],"cases":[137],"where":[138],"it":[139],"is":[140],"not":[141],"circumvent":[144],"studied":[146],"confounds,":[147],"which":[148],"similar":[154],"case-control":[155],"study.":[156]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}