{"id":"https://openalex.org/W2106429318","doi":"https://doi.org/10.1109/cbms.2002.1011352","title":"Time dependent cell growth in biomedical research with General Cell Screening System","display_name":"Time dependent cell growth in biomedical research with General Cell Screening System","publication_year":2003,"publication_date":"2003-06-25","ids":{"openalex":"https://openalex.org/W2106429318","doi":"https://doi.org/10.1109/cbms.2002.1011352","mag":"2106429318"},"language":"en","primary_location":{"id":"doi:10.1109/cbms.2002.1011352","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms.2002.1011352","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of 15th IEEE Symposium on Computer-Based Medical Systems (CBMS 2002)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088450084","display_name":"Gorazd Pretnar","orcid":null},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"G. Pretnar","raw_affiliation_strings":["Institut f\u00fcr Angewandte Mikrobiologie, (IAM) Universit\u00e4t f\u00fcr Bodenkultur, Vienna, Austria","Inst. fur Angewandte Mikrobiologie, Univ. fur Bodenkultur, Vienna, Austria"],"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Angewandte Mikrobiologie, (IAM) Universit\u00e4t f\u00fcr Bodenkultur, Vienna, Austria","institution_ids":[]},{"raw_affiliation_string":"Inst. fur Angewandte Mikrobiologie, Univ. fur Bodenkultur, Vienna, Austria","institution_ids":["https://openalex.org/I92869138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086789625","display_name":"Franz Steindl","orcid":null},"institutions":[{"id":"https://openalex.org/I92869138","display_name":"BOKU University","ror":"https://ror.org/057ff4y42","country_code":"AT","type":"education","lineage":["https://openalex.org/I92869138"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"F. Steindl","raw_affiliation_strings":["Institut f\u00fcr Angewandte Mikrobiologie, (IAM) Universit\u00e4t f\u00fcr Bodenkultur, Vienna, Austria","Inst. fur Angewandte Mikrobiologie, Univ. fur Bodenkultur, Vienna, Austria"],"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Angewandte Mikrobiologie, (IAM) Universit\u00e4t f\u00fcr Bodenkultur, Vienna, Austria","institution_ids":[]},{"raw_affiliation_string":"Inst. fur Angewandte Mikrobiologie, Univ. fur Bodenkultur, Vienna, Austria","institution_ids":["https://openalex.org/I92869138"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5088450084"],"corresponding_institution_ids":["https://openalex.org/I92869138"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13319302,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"41","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cell-growth","display_name":"Cell growth","score":0.5150437355041504},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.47705212235450745},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"Bone marrow","score":0.44597721099853516},{"id":"https://openalex.org/keywords/cell-culture","display_name":"Cell culture","score":0.4311884045600891},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3882662057876587},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3828129172325134},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3285136818885803},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.29572683572769165},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.23055362701416016},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.1524398922920227}],"concepts":[{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.5150437355041504},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.47705212235450745},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.44597721099853516},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.4311884045600891},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3882662057876587},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3828129172325134},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3285136818885803},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29572683572769165},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23055362701416016},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1524398922920227},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/cbms.2002.1011352","is_oa":false,"landing_page_url":"https://doi.org/10.1109/cbms.2002.1011352","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of 15th IEEE Symposium on Computer-Based Medical Systems (CBMS 2002)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1631250427","https://openalex.org/W1888326208","https://openalex.org/W1986415053","https://openalex.org/W2002287505","https://openalex.org/W2007736284","https://openalex.org/W2016364955","https://openalex.org/W2071187517","https://openalex.org/W2114918609","https://openalex.org/W2412897639","https://openalex.org/W2770334239"],"related_works":["https://openalex.org/W2072481810","https://openalex.org/W1985998670","https://openalex.org/W2143718611","https://openalex.org/W2083693850","https://openalex.org/W2347992620","https://openalex.org/W2361888356","https://openalex.org/W2320661246","https://openalex.org/W2354502831","https://openalex.org/W2351474733","https://openalex.org/W2028016879"],"abstract_inverted_index":{"Modern":[0],"and":[1,7,21,49,65,88,106,155,171,193,220,235,326],"effective":[2,8],"biomedical":[3,324],"research":[4],"needs":[5],"new":[6,163,323],"methods.":[9,40],"Use":[10],"of":[11,18,125,152,165,191,216,256,278,300,329],"96-well":[12],"micro-titre":[13],"plates":[14,36,209],"allows":[15],"the":[16,24,50,99,145,172,237,253,286,297],"performance":[17],"many":[19],"experiments":[20],"samples":[22],"under":[23],"same":[25],"conditions.":[26],"The":[27,133,149,243,289],"methods":[28,42],"used":[29],"to":[30,60,202,221,251,270],"determine":[31],"cell":[32,66,73,126,146,228,238,272,310],"numbers":[33],"in":[34,207,210,285,322,327],"these":[35],"are":[37,52,57],"all":[38],"end-point":[39],"These":[41],"allow":[43],"only":[44,248],"one":[45,196],"determination":[46],"per":[47],"plate,":[48],"cells":[51,206,262],"lost.":[53],"Usually,":[54],"such":[55],"assays":[56,77,331],"performed":[58,142],"according":[59],"concentration":[61],"dependance.":[62],"Other":[63],"parameters":[64],"growth":[67,74,127,218,229,239,273],"dynamics":[68],"remained":[69],"unrevealed.":[70],"To":[71,95],"reveal":[72],"dynamics,":[75],"multiple":[76,223],"should":[78],"be":[79,86,283],"performed.":[80,94],"Such":[81],"an":[82,156,167,319],"experimental":[83],"approach":[84],"would":[85],"expensive":[87],"time-consuming,":[89],"so":[90],"it":[91,306],"is":[92,116,135,183,307],"rarely":[93],"fill":[96],"this":[97],"gap,":[98],"Institut":[100],"fu/spl":[101],"uml/r":[102],"Angewandte":[103],"Mikrobiologie":[104],"(IAM)":[105],"SLT":[107],"Labinstruments":[108],"developed":[109],"GCSS":[110,115,173,199,267,293,316],"(General":[111],"Cell":[112],"Screening":[113],"System).":[114],"a":[117,138,153,159,162,177,184,211,308],"powerful":[118],"hardware/software":[119],"system":[120,150],"that":[121,305,315],"enables":[122],"continuous":[123],"monitoring":[124],"without":[128],"any":[129],"treatment":[130],"or":[131],"stain.":[132],"method":[134],"based":[136,194],"on":[137,144,195,259],"high-resolution":[139],"turbidity":[140],"measurement":[141,197],"directly":[143],"culture":[147],"plate.":[148],"consists":[151],"reader":[154],"eight-channel":[157],"photometer,":[158],"plate":[160],"with":[161,213,266,292],"form":[164],"wells,":[166],"Apple":[168],"Macintosh":[169],"computer":[170],"software.":[174],"We":[175,225,313],"chose":[176],"classic":[178],"bone-marrow":[179,227,309],"colony-count":[180,287],"assay,":[181],"which":[182,280],"typical":[185],"assay":[186,247],"scored":[187],"after":[188],"seven":[189,276],"days":[190,277],"incubation":[192,279],"only.":[198],"allowed":[200,249,268],"us":[201,269],"seed":[203],"bone":[204,245,260],"marrow":[205,246,261],"microtitre":[208],"medium":[212],"different":[214],"concentrations":[215],"haemopoietic":[217],"factors":[219],"perform":[222],"measurements.":[224],"observed":[226],"derived":[230],"from":[231,240],"interferon":[232,257,301],"alpha-treated":[233],"mice":[234],"compare":[236],"placebo-treated":[241],"mice.":[242],"classical":[244],"scientists":[250],"confirm":[252,296],"suppressive":[254,298],"nature":[255,299],"alpha":[258,302],"in-vivo.":[263,312],"Multiple":[264],"measurements":[265],"collect":[271],"data":[274,290],"over":[275],"could":[281,294],"not":[282,295],"seen":[284],"assay.":[288],"collected":[291],"but":[303],"revealed":[304],"activator":[311],"expect":[314],"will":[317],"have":[318],"important":[320],"influence":[321],"research,":[325],"corrections":[328],"established":[330],"too.":[332]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}