{"id":"https://openalex.org/W2289660091","doi":"https://doi.org/10.1109/bmei.2015.7401532","title":"Preparation and characteristics of diatrizoate meglumine-loaded chitosan microspheres","display_name":"Preparation and characteristics of diatrizoate meglumine-loaded chitosan microspheres","publication_year":2015,"publication_date":"2015-10-01","ids":{"openalex":"https://openalex.org/W2289660091","doi":"https://doi.org/10.1109/bmei.2015.7401532","mag":"2289660091"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2015.7401532","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2015.7401532","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013109772","display_name":"Yuming Huang","orcid":"https://orcid.org/0000-0001-7775-6787"},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuming Huang","raw_affiliation_strings":["College of Materials Science and Engineering, South China University of Technology, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Materials Science and Engineering, South China University of Technology, Guangzhou, China","institution_ids":["https://openalex.org/I90610280"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109576295","display_name":"Yurong Ji","orcid":null},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yurong Ji","raw_affiliation_strings":["College of Materials Science and Engineering, South China University of Technology, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Materials Science and Engineering, South China University of Technology, Guangzhou, China","institution_ids":["https://openalex.org/I90610280"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053150667","display_name":"Yonghua Lao","orcid":"https://orcid.org/0000-0003-1460-5994"},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yonghua Lao","raw_affiliation_strings":["College of Materials Science and Engineering, South China University of Technology, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Materials Science and Engineering, South China University of Technology, Guangzhou, China","institution_ids":["https://openalex.org/I90610280"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110015053","display_name":"Lan Yao","orcid":"https://orcid.org/0000-0002-9855-8162"},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lan Yao","raw_affiliation_strings":["College of Materials Science and Engineering, South China University of Technology, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Materials Science and Engineering, South China University of Technology, Guangzhou, China","institution_ids":["https://openalex.org/I90610280"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022747439","display_name":"Jianhui Song","orcid":"https://orcid.org/0000-0002-0715-6142"},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianhui Song","raw_affiliation_strings":["College of Materials Science and Engineering, South China University of Technology, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Materials Science and Engineering, South China University of Technology, Guangzhou, China","institution_ids":["https://openalex.org/I90610280"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085489555","display_name":"Xiaoxin Zhi","orcid":null},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoxin Zhi","raw_affiliation_strings":["College of Materials Science and Engineering, South China University of Technology, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Materials Science and Engineering, South China University of Technology, Guangzhou, China","institution_ids":["https://openalex.org/I90610280"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051052822","display_name":"Yueshan Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I90610280","display_name":"South China University of Technology","ror":"https://ror.org/0530pts50","country_code":"CN","type":"education","lineage":["https://openalex.org/I90610280"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yueshan Huang","raw_affiliation_strings":["College of Materials Science and Engineering, South China University of Technology, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Materials Science and Engineering, South China University of Technology, Guangzhou, China","institution_ids":["https://openalex.org/I90610280"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I90610280"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":null,"first_page":"371","last_page":"375"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10660","display_name":"Conducting polymers and applications","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10660","display_name":"Conducting polymers and applications","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10488","display_name":"Nanocomposite Films for Food Packaging","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chitosan","display_name":"Chitosan","score":0.6934017539024353},{"id":"https://openalex.org/keywords/swelling","display_name":"Swelling","score":0.6242311000823975},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.6059044599533081},{"id":"https://openalex.org/keywords/diatrizoate-meglumine","display_name":"Diatrizoate Meglumine","score":0.5627160668373108},{"id":"https://openalex.org/keywords/diatrizoate","display_name":"Diatrizoate","score":0.5165585279464722},{"id":"https://openalex.org/keywords/aqueous-solution","display_name":"Aqueous solution","score":0.4744483232498169},{"id":"https://openalex.org/keywords/aqueous-two-phase-system","display_name":"Aqueous two-phase system","score":0.46894311904907227},{"id":"https://openalex.org/keywords/zeta-potential","display_name":"Zeta potential","score":0.442125529050827},{"id":"https://openalex.org/keywords/glutaraldehyde","display_name":"Glutaraldehyde","score":0.42097195982933044},{"id":"https://openalex.org/keywords/chemical-engineering","display_name":"Chemical engineering","score":0.40495917201042175},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.3388240337371826},{"id":"https://openalex.org/keywords/nuclear-chemistry","display_name":"Nuclear chemistry","score":0.33620887994766235},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3322831392288208},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.2927303612232208},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.17058423161506653},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.08680757880210876},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.051454514265060425}],"concepts":[{"id":"https://openalex.org/C2779732960","wikidata":"https://www.wikidata.org/wiki/Q408510","display_name":"Chitosan","level":2,"score":0.6934017539024353},{"id":"https://openalex.org/C2778540859","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Swelling","level":2,"score":0.6242311000823975},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6059044599533081},{"id":"https://openalex.org/C2908884792","wikidata":"https://www.wikidata.org/wiki/Q411511","display_name":"Diatrizoate Meglumine","level":2,"score":0.5627160668373108},{"id":"https://openalex.org/C2776731598","wikidata":"https://www.wikidata.org/wiki/Q411511","display_name":"Diatrizoate","level":2,"score":0.5165585279464722},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.4744483232498169},{"id":"https://openalex.org/C149556010","wikidata":"https://www.wikidata.org/wiki/Q4782870","display_name":"Aqueous two-phase system","level":3,"score":0.46894311904907227},{"id":"https://openalex.org/C86181022","wikidata":"https://www.wikidata.org/wiki/Q196823","display_name":"Zeta potential","level":3,"score":0.442125529050827},{"id":"https://openalex.org/C2777529624","wikidata":"https://www.wikidata.org/wiki/Q416475","display_name":"Glutaraldehyde","level":2,"score":0.42097195982933044},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.40495917201042175},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3388240337371826},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.33620887994766235},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3322831392288208},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.2927303612232208},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.17058423161506653},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08680757880210876},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.051454514265060425},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2015.7401532","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2015.7401532","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Clean water and sanitation","score":0.8399999737739563,"id":"https://metadata.un.org/sdg/6"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1976928264","https://openalex.org/W2055492809","https://openalex.org/W2112460934","https://openalex.org/W2114424736","https://openalex.org/W2136784665","https://openalex.org/W2316423775","https://openalex.org/W2363113562","https://openalex.org/W6793275465"],"related_works":["https://openalex.org/W2046231566","https://openalex.org/W2413510391","https://openalex.org/W1979422173","https://openalex.org/W2155226666","https://openalex.org/W2407781127","https://openalex.org/W2352801165","https://openalex.org/W2089270641","https://openalex.org/W2370236537","https://openalex.org/W2415240551","https://openalex.org/W2334010495"],"abstract_inverted_index":{"The":[0,73,141],"purpose":[1],"of":[2,75,77,81,85,94,102,163,170,185,208],"the":[3,36,83,92,100,108,117,173,182,186,199,216,221,224],"present":[4],"study":[5,204],"is":[6],"to":[7,18,34,48,87,96],"prepare":[8],"a":[9,147,176,206],"diatrizoate":[10,78,142,187,209],"meglumine-loaded":[11,39,143,210],"chitosan":[12,40,50,144,189,211],"microsphere,":[13],"which":[14],"could":[15],"be":[16,19],"used":[17],"investigated":[20],"by":[21,44,107,153],"ultrasonic":[22,200],"imaging":[23,201],"technique":[24],"in":[25,192],"vivo":[26],"and":[27,63,99,112,128,133,136,150,156,166,195,219],"would":[28],"has":[29],"water":[30],"absorption":[31],"swelling":[32,135,183],"property":[33,184],"dredge":[35,220],"obstruction.":[37],"Diatrizoate":[38],"microspheres":[41,145,174,190],"were":[42,105,131,139],"prepared":[43,119],"crosslink":[45,71,103],"emulsification":[46],"process,":[47],"use":[49],"acetic":[51],"acid":[52],"solution":[53,69],"as":[54,59,66,70],"aqueous":[55,86],"phase,":[56,61],"liquid":[57,97],"paraffin":[58,98],"oil":[60],"Span80":[62,95],"n-butyl":[64],"alcohol":[65],"surfactant,":[67],"glutaraldehyde":[68],"agent.":[72],"effect":[74],"ratio":[76,84,93],"meglumine":[79],"(ratio":[80],"W),":[82],"organic":[88],"phase":[89],"(W/O":[90],"ratio),":[91],"time":[101],"process":[104],"optimized":[106],"single":[109],"factor":[110],"experiment":[111],"response":[113],"surface":[114],"experiment.":[115],"And":[116,181],"optimum":[118],"microspheres'":[120],"appearance,":[121],"distribution,":[122],"diameter,":[123],"zeta":[124,168],"potential,":[125],"thermal":[126],"performance":[127],"release":[129,179],"properties":[130,138],"measured":[132],"their":[134],"development":[137],"observed.":[140],"had":[146,175],"good":[148,177],"shape":[149],"uniform":[151],"distribution":[152],"light":[154],"microscope":[155],"transmission":[157],"electron":[158],"microscope,":[159],"with":[160],"average":[161,167],"diameters":[162],"1.53":[164],"\u03bcm":[165],"potential":[169],"-19.7":[171],"mV;":[172],"sustained":[178],"property.":[180],"megiumine-loaded":[188],"varied":[191],"different":[193],"conditions":[194],"developed":[196],"clearly":[197],"under":[198],"technique.":[202],"This":[203],"prepares":[205],"kind":[207],"microspheres,":[212,217],"who":[213],"can":[214],"make":[215],"develop":[218],"obstruction":[222],"at":[223],"same":[225],"time.":[226]},"counts_by_year":[],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}