{"id":"https://openalex.org/W1990865639","doi":"https://doi.org/10.1109/bmei.2012.6513134","title":"Adhesion and spreading of different skeletal cell types on variable surface coatings","display_name":"Adhesion and spreading of different skeletal cell types on variable surface coatings","publication_year":2012,"publication_date":"2012-10-01","ids":{"openalex":"https://openalex.org/W1990865639","doi":"https://doi.org/10.1109/bmei.2012.6513134","mag":"1990865639"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2012.6513134","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2012.6513134","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 5th International Conference on BioMedical Engineering and Informatics","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064860015","display_name":"Mikko J. Lammi","orcid":"https://orcid.org/0000-0002-6181-9904"},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Mikko J. Lammi","raw_affiliation_strings":["Institute of Biomedicine University of Eastern Finland, Kuopio, Finland","Inst. of Biomed., Univ. of Eastern Finland, Kuopio, Finland"],"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Inst. of Biomed., Univ. of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017726331","display_name":"Chengjuan Qu","orcid":"https://orcid.org/0000-0002-1710-7715"},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Chengjuan Qu","raw_affiliation_strings":["Institute of Biomedicine University of Eastern Finland, Kuopio, Finland","Inst. of Biomed., Univ. of Eastern Finland, Kuopio, Finland"],"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Inst. of Biomed., Univ. of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072767868","display_name":"Juha Prittinen","orcid":"https://orcid.org/0000-0003-2911-2981"},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Juha Prittinen","raw_affiliation_strings":["Institute of Biomedicine University of Eastern Finland, Kuopio, Finland","Inst. of Biomed., Univ. of Eastern Finland, Kuopio, Finland"],"affiliations":[{"raw_affiliation_string":"Institute of Biomedicine University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Inst. of Biomed., Univ. of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081325199","display_name":"Arto Koistinen","orcid":"https://orcid.org/0000-0001-7601-9806"},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Arto Koistinen","raw_affiliation_strings":["SIB-Labs University of Eastern Finland, Kuopio, Finland","SIB Labs, University of Eastern Finland, Kuopio, Finland"],"affiliations":[{"raw_affiliation_string":"SIB-Labs University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"SIB Labs, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038446667","display_name":"Sami Myllymaa","orcid":"https://orcid.org/0000-0002-9779-4358"},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Sami Myllymaa","raw_affiliation_strings":["SIB-Labs University of Eastern Finland, Kuopio, Finland","SIB Labs, University of Eastern Finland, Kuopio, Finland"],"affiliations":[{"raw_affiliation_string":"SIB-Labs University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"SIB Labs, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109865299","display_name":"Heikki Kr\u00f6ger","orcid":null},"institutions":[{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Heikki Kroger","raw_affiliation_strings":["Department of Orthopaedics and Traumatology, Kuopio University Hospital, Kuopio, Finland","Dept. of Orthopaedics & Traumatology, Kuopio Univ. Hosp., Kuopio, Finland"],"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics and Traumatology, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]},{"raw_affiliation_string":"Dept. of Orthopaedics & Traumatology, Kuopio Univ. Hosp., Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022651085","display_name":"Reijo Lappalainen","orcid":"https://orcid.org/0000-0003-3936-7478"},"institutions":[{"id":"https://openalex.org/I175532246","display_name":"University of Eastern Finland","ror":"https://ror.org/00cyydd11","country_code":"FI","type":"education","lineage":["https://openalex.org/I175532246"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Reijo Lappalainen","raw_affiliation_strings":["Department of Applied Physics, University of Eastern Finland, Kuopio, Finland","Dept. of Appl. Phys., Univ. of Eastern Finland, Kuopio, Finland"],"affiliations":[{"raw_affiliation_string":"Department of Applied Physics, University of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]},{"raw_affiliation_string":"Dept. of Appl. Phys., Univ. of Eastern Finland, Kuopio, Finland","institution_ids":["https://openalex.org/I175532246"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5064860015"],"corresponding_institution_ids":["https://openalex.org/I175532246"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.07862188,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"55","issue":null,"first_page":"705","last_page":"710"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10442","display_name":"Knee injuries and reconstruction techniques","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10059","display_name":"Bone Tissue Engineering Materials","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.39584943652153015},{"id":"https://openalex.org/keywords/stereochemistry","display_name":"Stereochemistry","score":0.3243004083633423},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.27534812688827515}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.39584943652153015},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3243004083633423},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.27534812688827515}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2012.6513134","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2012.6513134","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 5th International Conference on BioMedical Engineering and Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1971379267","https://openalex.org/W1973514306","https://openalex.org/W1988592246","https://openalex.org/W1997582330","https://openalex.org/W2004209532","https://openalex.org/W2008124574","https://openalex.org/W2008325216","https://openalex.org/W2027736364","https://openalex.org/W2031660324","https://openalex.org/W2032342275","https://openalex.org/W2033599059","https://openalex.org/W2044607889","https://openalex.org/W2049907112","https://openalex.org/W2054851985","https://openalex.org/W2061317061","https://openalex.org/W2063047035","https://openalex.org/W2064237012","https://openalex.org/W2066759293","https://openalex.org/W2081355343","https://openalex.org/W2092904432","https://openalex.org/W2094321869","https://openalex.org/W2098839229","https://openalex.org/W2102020759","https://openalex.org/W2108632470","https://openalex.org/W2130814631","https://openalex.org/W2135711029","https://openalex.org/W2146724122","https://openalex.org/W2153993860","https://openalex.org/W2157034185","https://openalex.org/W2167071495","https://openalex.org/W2314960873","https://openalex.org/W2323650198","https://openalex.org/W2402501616"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W4402299999","https://openalex.org/W4246450666","https://openalex.org/W4388998267","https://openalex.org/W2898370298","https://openalex.org/W2137437058","https://openalex.org/W4390401159","https://openalex.org/W2744391499","https://openalex.org/W2800070131","https://openalex.org/W4230250635"],"abstract_inverted_index":{"The":[0,48,94,162,202],"adhesion":[1,164,268],"and":[2,15,105,108,117,144,165,197,208,250,261,269,276],"spreading":[3,166,270],"of":[4,43,167,188,205,271],"human":[5,16],"bone":[6],"marrow-derived":[7],"mesenchymal":[8],"stem":[9],"cells":[10,170],"(hMSCs),":[11],"bovine":[12,114,199],"primary":[13,115,200,274],"chondrocytes":[14,116,207,275],"osteoblastic":[17],"osteosarcoma":[18],"cell":[19,46,182,219],"line":[20],"(Saos-2)":[21],"cultured":[22,121,169],"on":[23,35,81,186,218],"various":[24],"coated":[25,34,191,226],"surfaces":[26],"were":[27,99,120,171,221],"examined":[28,172],"to":[29],"determine":[30],"whether":[31],"different":[32,45,190,225],"materials":[33],"the":[36,41,44,82,168,180,189,224,267,272],"silicon":[37,83],"wafer":[38,84],"could":[39],"affect":[40],"growth":[42],"types.":[47],"amorphous":[49],"diamond":[50],"(AD),":[51],"titania":[52],"(TiO":[53],"<sub":[54,60,64,72,76,131,136,140,146,150,237,242,246,252,256],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[55,61,65,73,77,132,137,141,147,151,238,243,247,253,257],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sub>":[56,62,133,138,239,244],"),":[57],"alumina":[58],"(Al":[59],"O":[63,139,245],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">3</sub>":[66,74,142,148,248,254],")":[67,79],"or":[68],"carbon":[69],"nitride":[70],"(C":[71],"N":[75,149,255],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">4</sub>":[78,152,258],"coating":[80],"was":[85,157],"obtained":[86],"by":[87,194],"using":[88],"ultra":[89],"short":[90,229],"pulsed":[91,230],"laser":[92,231],"deposition.":[93],"differences":[95,217],"in":[96,125],"surface":[97],"characteristics":[98],"characterized":[100],"with":[101,128,159,173],"atomic":[102],"force":[103],"microscope":[104],"contact":[106,127],"angles":[107],"zeta":[109],"potential":[110],"measurements.":[111],"Human":[112,177],"MSCs,":[113,206],"Saos-2":[118,195,209,277],"osteoblasts":[119,210],"for":[122,266],"48":[123],"h":[124],"direct":[126],"AD-,":[129,235],"TiO":[130,236],"-,":[134,240],"Al":[135,241],"-":[143,249],"C":[145,251],"-coated":[153,259],"surfaces.":[154,227],"Cell":[155],"proliferation":[156,220],"assayed":[158],"MTT":[160],"assay.":[161],"morphology,":[163],"scanning":[174],"electron":[175],"microscope.":[176],"MSCs":[178],"had":[179],"highest":[181],"number":[183],"after":[184],"48-h-culture":[185],"all":[187],"surfaces,":[192,260],"followed":[193],"osteoblasts,":[196],"then":[198],"chondrocytes.":[201],"morphological":[203],"appearance":[204],"remained":[211],"as":[212],"original.":[213],"No":[214],"statistically":[215],"significant":[216],"found":[222],"among":[223],"Ultra":[228],"deposited":[232],"high":[233],"quality":[234],"provided":[262],"a":[263],"good":[264],"environment":[265],"hMSCs,":[273],"osteoblasts.":[278]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}