{"id":"https://openalex.org/W2093354201","doi":"https://doi.org/10.1109/bmei.2011.6098557","title":"Effect of Artemisia argyi polysaccharide on immunity activity of macrophages and T cells in mouse","display_name":"Effect of Artemisia argyi polysaccharide on immunity activity of macrophages and T cells in mouse","publication_year":2011,"publication_date":"2011-10-01","ids":{"openalex":"https://openalex.org/W2093354201","doi":"https://doi.org/10.1109/bmei.2011.6098557","mag":"2093354201"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2011.6098557","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2011.6098557","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065747238","display_name":"Zhong\u2010Juan Li","orcid":null},"institutions":[{"id":"https://openalex.org/I4210161227","display_name":"Huangshi Central Hospital","ror":"https://ror.org/05ncqj764","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161227"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li Zhongjuan","raw_affiliation_strings":["School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China"],"affiliations":[{"raw_affiliation_string":"School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","institution_ids":["https://openalex.org/I4210161227"]},{"raw_affiliation_string":"The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China","institution_ids":["https://openalex.org/I4210161227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074185833","display_name":"Yang Chaoling","orcid":null},"institutions":[{"id":"https://openalex.org/I4210161227","display_name":"Huangshi Central Hospital","ror":"https://ror.org/05ncqj764","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161227"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Chaoling","raw_affiliation_strings":["School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China"],"affiliations":[{"raw_affiliation_string":"School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","institution_ids":["https://openalex.org/I4210161227"]},{"raw_affiliation_string":"The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China","institution_ids":["https://openalex.org/I4210161227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100685092","display_name":"Jinghui Wang","orcid":"https://orcid.org/0000-0002-8462-3322"},"institutions":[{"id":"https://openalex.org/I4210161227","display_name":"Huangshi Central Hospital","ror":"https://ror.org/05ncqj764","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161227"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wang Jinghui","raw_affiliation_strings":["School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China"],"affiliations":[{"raw_affiliation_string":"School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","institution_ids":["https://openalex.org/I4210161227"]},{"raw_affiliation_string":"The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China","institution_ids":["https://openalex.org/I4210161227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103670619","display_name":"Yu Xin","orcid":null},"institutions":[{"id":"https://openalex.org/I4210161227","display_name":"Huangshi Central Hospital","ror":"https://ror.org/05ncqj764","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161227"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Xin","raw_affiliation_strings":["School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China"],"affiliations":[{"raw_affiliation_string":"School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei, China","institution_ids":["https://openalex.org/I4210161227"]},{"raw_affiliation_string":"The School of Medicine, Huangshi Institute of Technology, Huangshi, Hubei 435003, P R China","institution_ids":["https://openalex.org/I4210161227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014994716","display_name":"Hongliang Wang","orcid":"https://orcid.org/0000-0002-0802-6702"},"institutions":[{"id":"https://openalex.org/I4210161227","display_name":"Huangshi Central Hospital","ror":"https://ror.org/05ncqj764","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161227"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wang Hongliang","raw_affiliation_strings":["Huangshi Central Hospital, Huangshi, Hubei, China","Huangshi Central Hospital Huangshi, Hubei 435000, P R China"],"affiliations":[{"raw_affiliation_string":"Huangshi Central Hospital, Huangshi, Hubei, China","institution_ids":["https://openalex.org/I4210161227"]},{"raw_affiliation_string":"Huangshi Central Hospital Huangshi, Hubei 435000, P R China","institution_ids":["https://openalex.org/I4210161227"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065050892","display_name":"Zhong-Liang Zhai","orcid":null},"institutions":[{"id":"https://openalex.org/I4210161227","display_name":"Huangshi Central Hospital","ror":"https://ror.org/05ncqj764","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161227"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhai Zhongliang","raw_affiliation_strings":["Huangshi Central Hospital, Huangshi, Hubei, China","Huangshi Central Hospital Huangshi, Hubei 435000, P R China"],"affiliations":[{"raw_affiliation_string":"Huangshi Central Hospital, Huangshi, Hubei, China","institution_ids":["https://openalex.org/I4210161227"]},{"raw_affiliation_string":"Huangshi Central Hospital Huangshi, Hubei 435000, P R China","institution_ids":["https://openalex.org/I4210161227"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5065747238"],"corresponding_institution_ids":["https://openalex.org/I4210161227"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.13854303,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1416","last_page":"1419"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14331","display_name":"Medicinal Plant Pharmacodynamics Research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13483","display_name":"Herbal Medicine Research Studies","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phagocytosis","display_name":"Phagocytosis","score":0.8437865376472473},{"id":"https://openalex.org/keywords/macrophage","display_name":"Macrophage","score":0.7528363466262817},{"id":"https://openalex.org/keywords/in-vitro","display_name":"In vitro","score":0.5850390791893005},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.4961768090724945},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.4910407066345215},{"id":"https://openalex.org/keywords/peritoneal-cavity","display_name":"Peritoneal cavity","score":0.4824295938014984},{"id":"https://openalex.org/keywords/tumor-necrosis-factor-alpha","display_name":"Tumor necrosis factor alpha","score":0.4814700186252594},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.45887577533721924},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.4371175467967987},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4114639461040497},{"id":"https://openalex.org/keywords/lymphocyte","display_name":"Lymphocyte","score":0.41011568903923035},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.38654541969299316},{"id":"https://openalex.org/keywords/molecular-biology","display_name":"Molecular biology","score":0.37685155868530273},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.09921035170555115},{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.09231454133987427}],"concepts":[{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.8437865376472473},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.7528363466262817},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5850390791893005},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4961768090724945},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4910407066345215},{"id":"https://openalex.org/C2778536324","wikidata":"https://www.wikidata.org/wiki/Q1030169","display_name":"Peritoneal cavity","level":2,"score":0.4824295938014984},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.4814700186252594},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.45887577533721924},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.4371175467967987},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4114639461040497},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.41011568903923035},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38654541969299316},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.37685155868530273},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09921035170555115},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.09231454133987427},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2011.6098557","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2011.6098557","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1523770591","https://openalex.org/W2027730134","https://openalex.org/W2048406568","https://openalex.org/W2054671345","https://openalex.org/W2067801186","https://openalex.org/W2070222266","https://openalex.org/W2078074629","https://openalex.org/W2147387838"],"related_works":["https://openalex.org/W2260190197","https://openalex.org/W4376108479","https://openalex.org/W1526991771","https://openalex.org/W2022927757","https://openalex.org/W1967380358","https://openalex.org/W2362987367","https://openalex.org/W1950941645","https://openalex.org/W2355967221","https://openalex.org/W2583898521","https://openalex.org/W4214768350"],"abstract_inverted_index":{"To":[0],"study":[1],"the":[2,121,141,149,154,166,179,196,205],"immunoregulatory":[3],"action":[4],"of":[5,21,23,72,76,87,92,100,107,117,123,135,143,151,156,163,168,173,181,195,207],"Artemisia":[6],"argyi":[7],"polysaccharide":[8],"(AAP)":[9],"on":[10],"macrophage":[11],"cells":[12,15,137],"and":[13,46,54,63,120,125,170,193,209,213],"T":[14,215],"in":[16,43,48,60,64,67,82,94,102,110,127,138,153,165,178,211],"mice-":[17],"Methods:":[18],"The":[19,105,184],"percentage":[20],"phagocytosis":[22,75,90],"Staphylococcus":[24,77],"aureus":[25,78],"(STA)":[26],"by":[27,52],"mouse":[28],"macrophages":[29,93,101,111,129,212],"was":[30,38,97,113,130,159],"detected":[31,51],"through":[32],"Giemsa":[33],"dyeing.":[34],"Splenic":[35],"T-lymphocyte":[36],"proliferation":[37,150,180],"measured":[39],"with":[40,69],"MTT":[41],"assay":[42],"vitro.":[44,139],"IL-6":[45,124,192,208],"TNF-\u03b1":[47,126,194,210],"supernatants":[49],"were":[50],"ELISA":[53],"biological":[55],"assay.":[56],"Results:":[57],"Macrophages":[58],"both":[59],"peripheral":[61,103],"blood":[62],"abdominal":[65,95],"cavity":[66,96],"mice":[68,83],"i.p.":[70,85],"administration":[71,86],"AAP":[73,146,174,188,202],"showed":[74,175,186],"stonger":[79],"than":[80,115,133,161],"that":[81,99,116,134,162,187,201],"without":[84],"AAP,":[88],"while":[89],"index":[91],"higher":[98,132,160],"blood.":[104],"activity":[106,177],"antigen":[108],"presentation":[109],"group":[112],"stronger":[114],"B":[118,136],"cells,":[119],"production":[122],"activated":[128],"also":[131],"In":[140],"range":[142],"0.2~0.6":[144],"mg/ml,":[145],"could":[147,203],"enhance":[148],"lymphocyte":[152,164],"presence":[155],"macrophages,":[157,169],"which":[158,199],"absence":[167],"0.5":[171],"mg/ml":[172],"highest":[176],"lymphocytes.":[182],"Conclusion:":[183],"results":[185],"can":[189],"significantly":[190],"up-regulate":[191],"peritoneal":[197],"macrophage,":[198],"indicated":[200],"increase":[204],"expression":[206],"promote":[214],"cellular":[216],"immunity.":[217]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}