{"id":"https://openalex.org/W1969423252","doi":"https://doi.org/10.1109/bmei.2011.6098523","title":"Differential SHH and IHH expression during osteogenesis induced by Dexamethasone in rat bone marrow mesenchymal cells","display_name":"Differential SHH and IHH expression during osteogenesis induced by Dexamethasone in rat bone marrow mesenchymal cells","publication_year":2011,"publication_date":"2011-10-01","ids":{"openalex":"https://openalex.org/W1969423252","doi":"https://doi.org/10.1109/bmei.2011.6098523","mag":"1969423252"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2011.6098523","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2011.6098523","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100639020","display_name":"Xiaoli Ma","orcid":"https://orcid.org/0000-0003-0279-8354"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoli Ma","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039373992","display_name":"Shanshan Zu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanshan Zu","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045753153","display_name":"Yanfei Jia","orcid":"https://orcid.org/0000-0002-0670-1604"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanfei Jia","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088114400","display_name":"Yan Zheng","orcid":"https://orcid.org/0000-0003-4877-7292"},"institutions":[{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Zheng","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101530568","display_name":"Shuyi Han","orcid":"https://orcid.org/0000-0002-6520-7817"},"institutions":[{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuyi Han","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101979111","display_name":"Hua Liu","orcid":"https://orcid.org/0000-0002-8591-9205"},"institutions":[{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua Liu","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102964296","display_name":"Dongjie Xiao","orcid":"https://orcid.org/0000-0001-8605-1228"},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongjie Xiao","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100613239","display_name":"Yunshan Wang","orcid":"https://orcid.org/0000-0003-3767-6728"},"institutions":[{"id":"https://openalex.org/I4210106451","display_name":"Jinan Central Hospital","ror":"https://ror.org/01fr19c68","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106451"]},{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunshan Wang","raw_affiliation_strings":["Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China"],"affiliations":[{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]},{"raw_affiliation_string":"Medical Research and Laboratory Diagnostic Center, Jinan Central Hospital Affiliated to Shandong University, Jinan, 250013, China","institution_ids":["https://openalex.org/I4210106451","https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101994798","display_name":"Xueping Zhang","orcid":"https://orcid.org/0000-0003-2032-8831"},"institutions":[{"id":"https://openalex.org/I28006308","display_name":"Shandong Normal University","ror":"https://ror.org/01wy3h363","country_code":"CN","type":"education","lineage":["https://openalex.org/I28006308"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueping Zhang","raw_affiliation_strings":["College of Life Science, Shandong Normal University, Jinan, China","College of Life Science,Shandong Normal University,Jinan 250014,China)"],"affiliations":[{"raw_affiliation_string":"College of Life Science, Shandong Normal University, Jinan, China","institution_ids":["https://openalex.org/I28006308"]},{"raw_affiliation_string":"College of Life Science,Shandong Normal University,Jinan 250014,China)","institution_ids":["https://openalex.org/I28006308"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111116535","display_name":"Haiji Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I28006308","display_name":"Shandong Normal University","ror":"https://ror.org/01wy3h363","country_code":"CN","type":"education","lineage":["https://openalex.org/I28006308"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haiji Sun","raw_affiliation_strings":["College of Life Science, Shandong Normal University, Jinan, China","College of Life Science,Shandong Normal University,Jinan 250014,China)"],"affiliations":[{"raw_affiliation_string":"College of Life Science, Shandong Normal University, Jinan, China","institution_ids":["https://openalex.org/I28006308"]},{"raw_affiliation_string":"College of Life Science,Shandong Normal University,Jinan 250014,China)","institution_ids":["https://openalex.org/I28006308"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102088481","display_name":"Liguo An","orcid":null},"institutions":[{"id":"https://openalex.org/I28006308","display_name":"Shandong Normal University","ror":"https://ror.org/01wy3h363","country_code":"CN","type":"education","lineage":["https://openalex.org/I28006308"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liguo An","raw_affiliation_strings":["College of Life Science, Shandong Normal University, Jinan, China","College of Life Science,Shandong Normal University,Jinan 250014,China)"],"affiliations":[{"raw_affiliation_string":"College of Life Science, Shandong Normal University, Jinan, China","institution_ids":["https://openalex.org/I28006308"]},{"raw_affiliation_string":"College of Life Science,Shandong Normal University,Jinan 250014,China)","institution_ids":["https://openalex.org/I28006308"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5100639020"],"corresponding_institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4210106451"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05587625,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"373","issue":null,"first_page":"1204","last_page":"1208"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12009","display_name":"Hedgehog Signaling Pathway Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12009","display_name":"Hedgehog Signaling Pathway Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10975","display_name":"Bone Tumor Diagnosis and Treatments","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11787","display_name":"Oral and Maxillofacial Pathology","score":0.947700023651123,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sonic-hedgehog","display_name":"Sonic hedgehog","score":0.7008132338523865},{"id":"https://openalex.org/keywords/hedgehog-signaling-pathway","display_name":"Hedgehog signaling pathway","score":0.6967568397521973},{"id":"https://openalex.org/keywords/mesenchymal-stem-cell","display_name":"Mesenchymal stem cell","score":0.6888076066970825},{"id":"https://openalex.org/keywords/hedgehog","display_name":"Hedgehog","score":0.657042384147644},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.5731983184814453},{"id":"https://openalex.org/keywords/indian-hedgehog","display_name":"Indian hedgehog","score":0.5191173553466797},{"id":"https://openalex.org/keywords/cellular-differentiation","display_name":"Cellular differentiation","score":0.5084297060966492},{"id":"https://openalex.org/keywords/bone-marrow","display_name":"Bone marrow","score":0.4982879161834717},{"id":"https://openalex.org/keywords/stromal-cell","display_name":"Stromal cell","score":0.4689687490463257},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.43369218707084656},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.4283443093299866},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.4143826961517334},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3951239287853241},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.38687068223953247},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.25573664903640747},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.21070966124534607},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.19588670134544373},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.08221986889839172}],"concepts":[{"id":"https://openalex.org/C2776637008","wikidata":"https://www.wikidata.org/wiki/Q14860072","display_name":"Sonic hedgehog","level":3,"score":0.7008132338523865},{"id":"https://openalex.org/C88498014","wikidata":"https://www.wikidata.org/wiki/Q14859918","display_name":"Hedgehog signaling pathway","level":3,"score":0.6967568397521973},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.6888076066970825},{"id":"https://openalex.org/C2778539099","wikidata":"https://www.wikidata.org/wiki/Q6120","display_name":"Hedgehog","level":3,"score":0.657042384147644},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5731983184814453},{"id":"https://openalex.org/C2776014264","wikidata":"https://www.wikidata.org/wiki/Q1770532","display_name":"Indian hedgehog","level":4,"score":0.5191173553466797},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.5084297060966492},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.4982879161834717},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.4689687490463257},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43369218707084656},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4283443093299866},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4143826961517334},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3951239287853241},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38687068223953247},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.25573664903640747},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.21070966124534607},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19588670134544373},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08221986889839172},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2011.6098523","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2011.6098523","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1964618776","https://openalex.org/W1992865216","https://openalex.org/W1993982785","https://openalex.org/W1995499476","https://openalex.org/W1995833066","https://openalex.org/W2005123937","https://openalex.org/W2017204222","https://openalex.org/W2021054725","https://openalex.org/W2029515264","https://openalex.org/W2034741915","https://openalex.org/W2048057889","https://openalex.org/W2061001156","https://openalex.org/W2072130008","https://openalex.org/W2083910191","https://openalex.org/W2100721053","https://openalex.org/W2105054202","https://openalex.org/W2114455979","https://openalex.org/W2128473328","https://openalex.org/W2136222099","https://openalex.org/W2153720415","https://openalex.org/W2162699339","https://openalex.org/W2163341100","https://openalex.org/W4236944158","https://openalex.org/W4239966793"],"related_works":["https://openalex.org/W1585922331","https://openalex.org/W3087896481","https://openalex.org/W2060505600","https://openalex.org/W3008016544","https://openalex.org/W2378829050","https://openalex.org/W2380748750","https://openalex.org/W67834227","https://openalex.org/W2749322444","https://openalex.org/W2145249035","https://openalex.org/W1978833015"],"abstract_inverted_index":{"Hedgehog":[0,39,81,85,89,146],"signaling":[1,40,65,82,147,178],"pathway":[2,66],"is":[3],"an":[4,25],"important":[5,26],"signal":[6],"pathway,":[7],"which":[8,68],"regulates":[9],"the":[10,19,36,64,78,128,154,171,174],"development":[11],"of":[12,14,38,45,80,122,130,157,173,176],"variety":[13],"tissues":[15],"and":[16,57,87,150],"organs":[17],"in":[18,28,42,51,94,153,183],"embryonic":[20],"stage.":[21],"It":[22],"also":[23],"plays":[24],"role":[27,37,175],"osteogenesis.":[29,62],"However,":[30],"there":[31],"are":[32],"few":[33],"data":[34,188],"recording":[35],"molecules":[41,179],"osteogenic":[43,92,155,181],"differentiation":[44,72,93,121,156,182],"bone":[46,96,158,190],"marrow":[47,97,159],"mesenchymal":[48,98],"stem":[49,99],"cells":[50,100,161],"vitro.":[52],"Dexamethasone":[53,126,164],"(DEX),":[54],"a":[55],"synthetic":[56],"widely":[58],"used":[59],"glucocorticoid,":[60],"affects":[61,70],"And":[63],"by":[67,103,125,163],"DEX":[69],"osteoblastic":[71,120],"remains":[73],"obscure.":[74],"Here":[75],"to":[76,139],"investigate":[77],"expressions":[79],"molecules,":[83,148],"Sonic":[84],"(SHH)":[86],"Indian":[88],"(IHH),":[90],"during":[91,119],"rat":[95],"(MSCs)":[101],"induced":[102,124,162],"Dexamethasone.":[104],"In":[105],"this":[106],"study,":[107],"we":[108],"found":[109],"that":[110,145],"SHH":[111,149],"expression":[112,117],"significantly":[113],"increased":[114],"while":[115],"IHH":[116],"decreased":[118],"MSCs":[123,184],"at":[127],"concentration":[129],"10":[131],"<sup":[132],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[133],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">-7</sup>":[134],"M":[135],"from":[136],"7":[137],"days":[138],"21":[140],"days.":[141],"These":[142],"findings":[143],"suggest":[144],"IHH,":[151],"involve":[152],"stromal":[160],"with":[165],"various":[166],"effects.":[167],"To":[168],"further":[169],"study":[170],"mechanism":[172],"Hh":[177],"on":[180],"would":[185],"provide":[186],"new":[187],"for":[189],"tissue":[191],"engineering.":[192]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
