{"id":"https://openalex.org/W2011409658","doi":"https://doi.org/10.1109/bmei.2011.6098326","title":"Influence of NR gene inhibition on cell senescence and growth and development","display_name":"Influence of NR gene inhibition on cell senescence and growth and development","publication_year":2011,"publication_date":"2011-10-01","ids":{"openalex":"https://openalex.org/W2011409658","doi":"https://doi.org/10.1109/bmei.2011.6098326","mag":"2011409658"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2011.6098326","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2011.6098326","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101691458","display_name":"Jinghui Yang","orcid":"https://orcid.org/0000-0001-6213-2509"},"institutions":[{"id":"https://openalex.org/I11849452","display_name":"Tianjin Agricultural University","ror":"https://ror.org/0010b6s72","country_code":"CN","type":"education","lineage":["https://openalex.org/I11849452"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jinghui Yang","raw_affiliation_strings":["Department of Horticulture, Tianjin Agricultural University, Tianjin, China","The Department of Horticulture, Tianjin Agricultural University, Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]},{"raw_affiliation_string":"The Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052653569","display_name":"Y. Liu","orcid":"https://orcid.org/0000-0001-5968-3932"},"institutions":[{"id":"https://openalex.org/I11849452","display_name":"Tianjin Agricultural University","ror":"https://ror.org/0010b6s72","country_code":"CN","type":"education","lineage":["https://openalex.org/I11849452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanjun Liu","raw_affiliation_strings":["Department of Horticulture, Tianjin Agricultural University, Tianjin, China","The Department of Horticulture, Tianjin Agricultural University, Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]},{"raw_affiliation_string":"The Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100779521","display_name":"Jianke Li","orcid":"https://orcid.org/0000-0003-4183-7336"},"institutions":[{"id":"https://openalex.org/I11849452","display_name":"Tianjin Agricultural University","ror":"https://ror.org/0010b6s72","country_code":"CN","type":"education","lineage":["https://openalex.org/I11849452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianke Li","raw_affiliation_strings":["Department of Horticulture, Tianjin Agricultural University, Tianjin, China","The Department of Horticulture, Tianjin Agricultural University, Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]},{"raw_affiliation_string":"The Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110375111","display_name":"Huang Jun-xuan","orcid":null},"institutions":[{"id":"https://openalex.org/I11849452","display_name":"Tianjin Agricultural University","ror":"https://ror.org/0010b6s72","country_code":"CN","type":"education","lineage":["https://openalex.org/I11849452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junxuan Huang","raw_affiliation_strings":["Department of Horticulture, Tianjin Agricultural University, Tianjin, China","The Department of Horticulture, Tianjin Agricultural University, Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]},{"raw_affiliation_string":"The Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005551542","display_name":"Chunxia Wu","orcid":"https://orcid.org/0000-0002-4454-6035"},"institutions":[{"id":"https://openalex.org/I11849452","display_name":"Tianjin Agricultural University","ror":"https://ror.org/0010b6s72","country_code":"CN","type":"education","lineage":["https://openalex.org/I11849452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunxia Wu","raw_affiliation_strings":["Department of Horticulture, Tianjin Agricultural University, Tianjin, China","The Department of Horticulture, Tianjin Agricultural University, Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]},{"raw_affiliation_string":"The Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069411879","display_name":"Shuangyue Li","orcid":"https://orcid.org/0000-0002-7843-8630"},"institutions":[{"id":"https://openalex.org/I11849452","display_name":"Tianjin Agricultural University","ror":"https://ror.org/0010b6s72","country_code":"CN","type":"education","lineage":["https://openalex.org/I11849452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuangyue Li","raw_affiliation_strings":["Department of Horticulture, Tianjin Agricultural University, Tianjin, China","The Department of Horticulture, Tianjin Agricultural University, Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]},{"raw_affiliation_string":"The Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101940301","display_name":"Yudong Liu","orcid":"https://orcid.org/0000-0003-0001-6208"},"institutions":[{"id":"https://openalex.org/I11849452","display_name":"Tianjin Agricultural University","ror":"https://ror.org/0010b6s72","country_code":"CN","type":"education","lineage":["https://openalex.org/I11849452"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yudong Liu","raw_affiliation_strings":["Department of Horticulture, Tianjin Agricultural University, Tianjin, China","The Department of Horticulture, Tianjin Agricultural University, Tianjin, China"],"affiliations":[{"raw_affiliation_string":"Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]},{"raw_affiliation_string":"The Department of Horticulture, Tianjin Agricultural University, Tianjin, China","institution_ids":["https://openalex.org/I11849452"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5101691458"],"corresponding_institution_ids":["https://openalex.org/I11849452"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10897154,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"8","issue":null,"first_page":"333","last_page":"337"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10473","display_name":"Postharvest Quality and Shelf Life Management","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10473","display_name":"Postharvest Quality and Shelf Life Management","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.9879000186920166,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mutant","display_name":"Mutant","score":0.7892438173294067},{"id":"https://openalex.org/keywords/ripening","display_name":"Ripening","score":0.7102341651916504},{"id":"https://openalex.org/keywords/transpiration","display_name":"Transpiration","score":0.691561222076416},{"id":"https://openalex.org/keywords/ethylene","display_name":"Ethylene","score":0.6216259002685547},{"id":"https://openalex.org/keywords/horticulture","display_name":"Horticulture","score":0.6017236113548279},{"id":"https://openalex.org/keywords/intracellular","display_name":"Intracellular","score":0.5772147178649902},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.544892430305481},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4817788302898407},{"id":"https://openalex.org/keywords/wild-type","display_name":"Wild type","score":0.47560200095176697},{"id":"https://openalex.org/keywords/stomatal-conductance","display_name":"Stomatal conductance","score":0.4732830226421356},{"id":"https://openalex.org/keywords/respiration","display_name":"Respiration","score":0.4451088309288025},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.437791109085083},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.4308618903160095},{"id":"https://openalex.org/keywords/senescence","display_name":"Senescence","score":0.4238385260105133},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.40735021233558655},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.38276538252830505},{"id":"https://openalex.org/keywords/botany","display_name":"Botany","score":0.3619407117366791},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.279596209526062},{"id":"https://openalex.org/keywords/photosynthesis","display_name":"Photosynthesis","score":0.16080787777900696}],"concepts":[{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.7892438173294067},{"id":"https://openalex.org/C172353545","wikidata":"https://www.wikidata.org/wiki/Q2121926","display_name":"Ripening","level":2,"score":0.7102341651916504},{"id":"https://openalex.org/C157517311","wikidata":"https://www.wikidata.org/wiki/Q167980","display_name":"Transpiration","level":3,"score":0.691561222076416},{"id":"https://openalex.org/C2778597550","wikidata":"https://www.wikidata.org/wiki/Q151313","display_name":"Ethylene","level":3,"score":0.6216259002685547},{"id":"https://openalex.org/C144027150","wikidata":"https://www.wikidata.org/wiki/Q48803","display_name":"Horticulture","level":1,"score":0.6017236113548279},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.5772147178649902},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.544892430305481},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4817788302898407},{"id":"https://openalex.org/C207583985","wikidata":"https://www.wikidata.org/wiki/Q128723","display_name":"Wild type","level":4,"score":0.47560200095176697},{"id":"https://openalex.org/C2781045423","wikidata":"https://www.wikidata.org/wiki/Q7618701","display_name":"Stomatal conductance","level":3,"score":0.4732830226421356},{"id":"https://openalex.org/C182215343","wikidata":"https://www.wikidata.org/wiki/Q472287","display_name":"Respiration","level":2,"score":0.4451088309288025},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.437791109085083},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4308618903160095},{"id":"https://openalex.org/C522857546","wikidata":"https://www.wikidata.org/wiki/Q2070979","display_name":"Senescence","level":2,"score":0.4238385260105133},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40735021233558655},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38276538252830505},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3619407117366791},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.279596209526062},{"id":"https://openalex.org/C183688256","wikidata":"https://www.wikidata.org/wiki/Q11982","display_name":"Photosynthesis","level":2,"score":0.16080787777900696},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2011.6098326","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2011.6098326","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W45198557","https://openalex.org/W1965251889","https://openalex.org/W1969039765","https://openalex.org/W1971922509","https://openalex.org/W1980970732","https://openalex.org/W1986372384","https://openalex.org/W1989075462","https://openalex.org/W2003190329","https://openalex.org/W2036327149","https://openalex.org/W2046800513","https://openalex.org/W2061025166","https://openalex.org/W2073205776","https://openalex.org/W2079440628","https://openalex.org/W2080392291","https://openalex.org/W2093175028","https://openalex.org/W2094093931","https://openalex.org/W2097808091","https://openalex.org/W2099062019","https://openalex.org/W2123582659","https://openalex.org/W2139031759","https://openalex.org/W2141332926","https://openalex.org/W2145402998","https://openalex.org/W2148299987","https://openalex.org/W2162806397","https://openalex.org/W2171463459","https://openalex.org/W2314225431","https://openalex.org/W6601873142"],"related_works":["https://openalex.org/W2104823949","https://openalex.org/W1743194206","https://openalex.org/W2006383267","https://openalex.org/W2507777765","https://openalex.org/W4312311831","https://openalex.org/W2354431528","https://openalex.org/W2802775126","https://openalex.org/W2352340891","https://openalex.org/W2904543189","https://openalex.org/W2369234026"],"abstract_inverted_index":{"To":[0],"understand":[1],"function":[2],"of":[3,23,35,48,50,60,67,113,120,124,153,167,174,193,219,224],"NR":[4,13,51],"gene":[5,14,52],"roundly":[6,30],"and":[7,20,25,27,79,85,97,117,122,189,197,221],"get":[8],"new":[9],"breeding":[10],"material,":[11],"the":[12,21,41,118,150,171,198],"was":[15,63,88,101,115,126,195,202],"down-regulated":[16],"by":[17],"antisense":[18],"inhibition":[19],"reaction":[22],"physiological":[24],"growth":[26],"development":[28,154,175],"were":[29,83,137],"researched":[31],"in":[32,69,90,94,103,106,128,132,140,146,204,207,209],"nr":[33,129],"mutants":[34,62],"tomato.":[36],"The":[37,74,111,134,143,165,186,212],"result":[38,213],"shows":[39],"that":[40],"wild-type":[42],"fruits":[43,194],"(wt)":[44],"have":[45],"higher":[46,84,102],"level":[47],"expression":[49],"than":[53,66,93,105,131,206],"nr1,":[54,91,147,168],"nr2,":[55],"nr3,":[56],"nr4.":[57],"Ethylene":[58],"synthesis":[59],"all":[61,70],"much":[64],"lower":[65,89,196],"wt":[68,95,107,208],"fruit":[71,145,166],"ripening":[72],"stage.":[73],"transpiration":[75],"rate,":[76],"stomatal":[77],"conductance":[78],"cell":[80],"membrane":[81],"permeability":[82],"respiration":[86],"rate":[87],"nr2":[92,148,169],"plants":[96],"intercellular":[98],"CO2":[99],"concentration":[100],"nr1":[104,205],"with":[108,163,184],"T1":[109],"leaves.":[110],"number":[112],"branches":[114],"less":[116],"length":[119],"internode":[121],"diameter":[123],"stem":[125,199],"more":[127],"lines":[130],"wt.":[133,164,185],"color":[135],"changes":[136],"substantially":[138],"delayed":[139,161,182],"mutant":[141,144],"fruits.":[142],"reached":[149,170],"breaker":[151],"stage":[152,173],"at":[155,176],"approximately":[156,177],"7":[157],"weeks,":[158,179],"7-9":[159],"days":[160,181],"compared":[162,183],"hypermature":[172],"12.5":[178],"37-38":[180],"rot":[187],"percent":[188,192],"weight":[190],"loss":[191],"pull":[200],"force":[201],"stronger":[203],"room":[210],"store.":[211],"could":[214],"be":[215],"relative":[216],"to":[217],"interplay":[218],"receptors":[220],"functionally":[222],"redundant":[223],"ethylene":[225],"receptors.":[226]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}