{"id":"https://openalex.org/W2102477793","doi":"https://doi.org/10.1109/bmei.2009.5304822","title":"Evaluation of Novel Protein Structure Comparison Algorithms Based on Objective Function Rankings","display_name":"Evaluation of Novel Protein Structure Comparison Algorithms Based on Objective Function Rankings","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2102477793","doi":"https://doi.org/10.1109/bmei.2009.5304822","mag":"2102477793"},"language":"en","primary_location":{"id":"doi:10.1109/bmei.2009.5304822","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5304822","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073585109","display_name":"Hitomi Hasegawa","orcid":null},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Hitomi Hasegawa","raw_affiliation_strings":["Institute of Biotechnology, University of Helsinki, Helsinki, Finland","Inst. of Biotechnol., Univ. of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biotechnology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Inst. of Biotechnol., Univ. of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064498279","display_name":"Liisa Holm","orcid":"https://orcid.org/0000-0002-7807-2966"},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Liisa Holm","raw_affiliation_strings":["Institute of Biotechnology, University of Helsinki, Helsinki, Finland","Inst. of Biotechnol., Univ. of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biotechnology, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Inst. of Biotechnol., Univ. of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I133731052"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"4983","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9944999814033508,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6166673898696899},{"id":"https://openalex.org/keywords/protein-structure-prediction","display_name":"Protein structure prediction","score":0.5881394743919373},{"id":"https://openalex.org/keywords/protein-structure","display_name":"Protein structure","score":0.565548300743103},{"id":"https://openalex.org/keywords/evolutionary-algorithm","display_name":"Evolutionary algorithm","score":0.5340645909309387},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.5292139649391174},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.46320855617523193},{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.4617016911506653},{"id":"https://openalex.org/keywords/protein-function","display_name":"Protein function","score":0.44970035552978516},{"id":"https://openalex.org/keywords/data-structure","display_name":"Data structure","score":0.4465496242046356},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.358354389667511},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.344356894493103},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3215482234954834},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1570201814174652}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6166673898696899},{"id":"https://openalex.org/C18051474","wikidata":"https://www.wikidata.org/wiki/Q899656","display_name":"Protein structure prediction","level":3,"score":0.5881394743919373},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.565548300743103},{"id":"https://openalex.org/C159149176","wikidata":"https://www.wikidata.org/wiki/Q14489129","display_name":"Evolutionary algorithm","level":2,"score":0.5340645909309387},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.5292139649391174},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.46320855617523193},{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.4617016911506653},{"id":"https://openalex.org/C2986374874","wikidata":"https://www.wikidata.org/wiki/Q8054","display_name":"Protein function","level":3,"score":0.44970035552978516},{"id":"https://openalex.org/C162319229","wikidata":"https://www.wikidata.org/wiki/Q175263","display_name":"Data structure","level":2,"score":0.4465496242046356},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.358354389667511},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.344356894493103},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3215482234954834},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1570201814174652},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bmei.2009.5304822","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bmei.2009.5304822","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2009 2nd International Conference on Biomedical Engineering and Informatics","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","score":0.5299999713897705,"display_name":"Industry, innovation and infrastructure"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1484746734","https://openalex.org/W1550808487","https://openalex.org/W1801992990","https://openalex.org/W1967538863","https://openalex.org/W1972718882","https://openalex.org/W1984197379","https://openalex.org/W2002419486","https://openalex.org/W2009836662","https://openalex.org/W2031901496","https://openalex.org/W2042454166","https://openalex.org/W2057251215","https://openalex.org/W2069694163","https://openalex.org/W2077235131","https://openalex.org/W2081941928","https://openalex.org/W2096943217","https://openalex.org/W2108361377","https://openalex.org/W2137146016","https://openalex.org/W2148823738","https://openalex.org/W2161899160","https://openalex.org/W2168964504","https://openalex.org/W4388384043","https://openalex.org/W6652751874"],"related_works":["https://openalex.org/W2946599741","https://openalex.org/W2593264178","https://openalex.org/W3171039768","https://openalex.org/W2136856901","https://openalex.org/W2368468053","https://openalex.org/W2058542300","https://openalex.org/W2043066834","https://openalex.org/W1564749278","https://openalex.org/W2294851134","https://openalex.org/W3215498386"],"abstract_inverted_index":{"Protein":[0],"structure":[1,14,20,40,90],"comparison":[2,41,49,91],"is":[3,15,42,74],"a":[4,75,85],"important":[5],"and":[6,45,66,68,79,105],"developing":[7],"area":[8],"in":[9],"Bioinformatics.":[10],"Understanding":[11],"the":[12,27,58],"protein":[13,19,33,89],"very":[16],"useful,":[17],"since":[18],"suffers":[21],"less":[22],"evolutionary":[23,80],"changes":[24],"compared":[25,97],"to":[26],"amino":[28],"acid":[29],"sequences.":[30],"Thus,":[31],"comparing":[32],"structures":[34],"provides":[35],"additional":[36],"evolution":[37],"information.":[38],"However,":[39],"not":[43,95],"straightforward":[44],"multiple":[46],"algorithms":[47,61,92],"for":[48],"have":[50,94],"emerged":[51],"recently.":[52],"In":[53],"this":[54],"paper":[55],"we":[56,102],"evaluate":[57,106],"performance":[59],"of":[60,77,88],"based":[62],"on":[63],"contact":[64],"maps":[65],"Calpha,":[67],"their":[69],"respective":[70],"objective":[71],"function,":[72],"which":[73],"measure":[76],"biological":[78],"importance.":[81],"The":[82],"contributions":[83],"are":[84],"state-of-the-art":[86],"review":[87],"that":[93],"been":[96],"with":[98],"other":[99],"servers.":[100],"Further,":[101],"compare":[103],"findings":[104],"them":[107],"across":[108],"others":[109],"methods":[110],"already":[111],"proven":[112],"effective.":[113]},"counts_by_year":[],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}