{"id":"https://openalex.org/W2906497692","doi":"https://doi.org/10.1109/biocas.2018.8584802","title":"Links Between DNA-Based Diet and Salivary Leptin Hormone Concentration","display_name":"Links Between DNA-Based Diet and Salivary Leptin Hormone Concentration","publication_year":2018,"publication_date":"2018-10-01","ids":{"openalex":"https://openalex.org/W2906497692","doi":"https://doi.org/10.1109/biocas.2018.8584802","mag":"2906497692"},"language":"en","primary_location":{"id":"doi:10.1109/biocas.2018.8584802","is_oa":false,"landing_page_url":"https://doi.org/10.1109/biocas.2018.8584802","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023567308","display_name":"Francesca Romana Cavallo","orcid":"https://orcid.org/0000-0003-3122-1749"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Francesca R. Cavallo","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018680323","display_name":"Khalid B. Mirza","orcid":"https://orcid.org/0000-0001-8754-6468"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Khalid B. Mirza","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035891124","display_name":"C. Toumazou","orcid":"https://orcid.org/0000-0001-8773-7360"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christofer Toumazou","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Imperial College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I47508984"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13547918,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11584","display_name":"Biochemical Analysis and Sensing Techniques","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leptin","display_name":"Leptin","score":0.9281350374221802},{"id":"https://openalex.org/keywords/statistical-significance","display_name":"Statistical significance","score":0.6563208103179932},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"Body mass index","score":0.579718291759491},{"id":"https://openalex.org/keywords/saliva","display_name":"Saliva","score":0.562111496925354},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.49288034439086914},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.48809874057769775},{"id":"https://openalex.org/keywords/hormone","display_name":"Hormone","score":0.46324196457862854},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4447267949581146},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.4375225901603699},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3244757652282715},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.2988945245742798},{"id":"https://openalex.org/keywords/obesity","display_name":"Obesity","score":0.24738198518753052},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.1392616331577301},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09677457809448242}],"concepts":[{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.9281350374221802},{"id":"https://openalex.org/C65409693","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Statistical significance","level":2,"score":0.6563208103179932},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.579718291759491},{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.562111496925354},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.49288034439086914},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48809874057769775},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.46324196457862854},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4447267949581146},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.4375225901603699},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3244757652282715},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.2988945245742798},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.24738198518753052},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1392616331577301},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09677457809448242}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/biocas.2018.8584802","is_oa":false,"landing_page_url":"https://doi.org/10.1109/biocas.2018.8584802","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE Biomedical Circuits and Systems Conference (BioCAS)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6991775769","display_name":null,"funder_award_id":"EP/N002474/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1999276645","https://openalex.org/W2001102352","https://openalex.org/W2015130768","https://openalex.org/W2083099365","https://openalex.org/W2085510141","https://openalex.org/W2158736855","https://openalex.org/W2158919206","https://openalex.org/W2162060216","https://openalex.org/W2168271936","https://openalex.org/W2168647804","https://openalex.org/W2268001801","https://openalex.org/W4205732044","https://openalex.org/W4236311082","https://openalex.org/W4238066266","https://openalex.org/W4254620922"],"related_works":["https://openalex.org/W2212975813","https://openalex.org/W2155584699","https://openalex.org/W3214746088","https://openalex.org/W3144829101","https://openalex.org/W4388337094","https://openalex.org/W2402028051","https://openalex.org/W2319742058","https://openalex.org/W4220671203","https://openalex.org/W2075494673","https://openalex.org/W2143022745"],"abstract_inverted_index":{"Highly":[0],"personalised":[1],"dietary":[2],"advice":[3],"based":[4,139],"on":[5,50,140],"combination":[6],"of":[7,23,33,59,92,114,158],"genetic":[8],"information,":[9],"such":[10],"as":[11],"Single":[12],"Nucleotide":[13],"Poly-morphisms":[14],"(SNPs)":[15],"and":[16,53,82,95,100,125,133],"`nudge'":[17],"theory":[18],"is":[19,37],"an":[20],"emerging":[21],"field":[22],"research":[24],"towards":[25],"a":[26,28,44,112],"achieving":[27],"healthy":[29],"lifestyle.":[30],"The":[31,73],"aim":[32],"this":[34],"preliminary":[35],"study":[36,85],"to":[38,64,152],"explore":[39],"possible":[40],"links":[41,68],"between":[42,130],"leptin,":[43],"hormone":[45],"which":[46,98],"regulates":[47],"energy":[48],"balance":[49],"the":[51,107,141],"body":[52],"DNA-based":[54,103],"diet.":[55],"A":[56],"trial":[57],"composed":[58],"23":[60],"subjects":[61],"was":[62,76,111,128],"run":[63],"investigate":[65],"whether":[66],"nutrigenomic":[67],"exist":[69],"for":[70],"salivary":[71,131],"leptin.":[72],"collected":[74],"sample":[75],"analysed":[77],"by":[78],"ELISA,":[79],"statistical":[80,121,126],"methods":[81],"regression.":[83],"This":[84],"compared":[86],"leptin":[87,116,132,145],"concentrations":[88],"over":[89],"8":[90],"weeks":[91],"Intervention":[93,108],"group":[94],"Control":[96],"group,":[97,109],"follow":[99,102],"not":[101],"diet":[104],"respectively.":[105],"For":[106],"there":[110],"trend":[113],"decreased":[115],"concentration,":[117],"however":[118],"without":[119],"any":[120],"significance.":[122],"Overall,":[123],"correlation":[124],"significance":[127],"found":[129],"calorific":[134],"intake.":[135],"Moreover,":[136],"regression":[137],"models":[138],"data":[142],"showed":[143],"that":[144],"levels":[146],"in":[147],"saliva":[148],"can":[149],"be":[150],"used":[151],"predict":[153],"Body":[154],"Mass":[155],"Index":[156],"(RMI)":[157],"subjects.":[159]},"counts_by_year":[],"updated_date":"2026-06-26T08:34:08.712188","created_date":"2025-10-10T00:00:00"}