{"id":"https://openalex.org/W4406458715","doi":"https://doi.org/10.1109/bigdata62323.2024.10825036","title":"Noise2Inverse for 3D Low-Dose Cone-Beam Computed Tomography","display_name":"Noise2Inverse for 3D Low-Dose Cone-Beam Computed Tomography","publication_year":2024,"publication_date":"2024-12-15","ids":{"openalex":"https://openalex.org/W4406458715","doi":"https://doi.org/10.1109/bigdata62323.2024.10825036"},"language":"en","primary_location":{"id":"doi:10.1109/bigdata62323.2024.10825036","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bigdata62323.2024.10825036","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Big Data (BigData)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075900464","display_name":"Austin Yunker","orcid":"https://orcid.org/0009-0004-7253-6370"},"institutions":[{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Austin Yunker","raw_affiliation_strings":["Argonne National Laboratory,Data Science and Learning Division,Lemont,IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Argonne National Laboratory,Data Science and Learning Division,Lemont,IL","institution_ids":["https://openalex.org/I1282105669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031353482","display_name":"Jason Luce","orcid":null},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Luce","raw_affiliation_strings":["Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL","institution_ids":["https://openalex.org/I1925986","https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032182498","display_name":"John C. Roeske","orcid":"https://orcid.org/0000-0002-5829-4254"},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John C. Roeske","raw_affiliation_strings":["Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL","institution_ids":["https://openalex.org/I1925986","https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068373159","display_name":"Rajkumar Kettimuthu","orcid":"https://orcid.org/0000-0002-0046-9883"},"institutions":[{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rajkumar Kettimuthu","raw_affiliation_strings":["Argonne National Laboratory,Data Science and Learning Division,Lemont,IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Argonne National Laboratory,Data Science and Learning Division,Lemont,IL","institution_ids":["https://openalex.org/I1282105669"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022223056","display_name":"Hyejoo Kang","orcid":"https://orcid.org/0000-0002-4433-0939"},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hyejoo Kang","raw_affiliation_strings":["Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL","institution_ids":["https://openalex.org/I1925986","https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049645185","display_name":"S\u00e9bastien Gros","orcid":"https://orcid.org/0000-0001-6054-2133"},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sebastien Gros","raw_affiliation_strings":["Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL","institution_ids":["https://openalex.org/I1925986","https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112691308","display_name":"Alec M. Block","orcid":null},"institutions":[{"id":"https://openalex.org/I1925986","display_name":"Loyola University Chicago","ror":"https://ror.org/04b6x2g63","country_code":"US","type":"education","lineage":["https://openalex.org/I1925986"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alec M. Block","raw_affiliation_strings":["Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardinal Bernadin Cancer Center, Loyola University of Chicago,Stritch School of Medicine,Department of Radiation Oncology,Maywood,IL","institution_ids":["https://openalex.org/I1925986","https://openalex.org/I40347166"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0975,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.80267079,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"2057","last_page":"2064"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cone-beam-computed-tomography","display_name":"Cone beam computed tomography","score":0.7419925332069397},{"id":"https://openalex.org/keywords/computed-tomography","display_name":"Computed tomography","score":0.6751907467842102},{"id":"https://openalex.org/keywords/beam","display_name":"Beam (structure)","score":0.48522260785102844},{"id":"https://openalex.org/keywords/cone","display_name":"Cone (formal languages)","score":0.4255954623222351},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.34557121992111206},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.31935933232307434},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.31541794538497925},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.3087661862373352},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.18604665994644165},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.15978017449378967},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.08278840780258179}],"concepts":[{"id":"https://openalex.org/C2779813781","wikidata":"https://www.wikidata.org/wiki/Q1224951","display_name":"Cone beam computed tomography","level":3,"score":0.7419925332069397},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.6751907467842102},{"id":"https://openalex.org/C168834538","wikidata":"https://www.wikidata.org/wiki/Q3705329","display_name":"Beam (structure)","level":2,"score":0.48522260785102844},{"id":"https://openalex.org/C30014739","wikidata":"https://www.wikidata.org/wiki/Q5159445","display_name":"Cone (formal languages)","level":2,"score":0.4255954623222351},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.34557121992111206},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.31935933232307434},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31541794538497925},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3087661862373352},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18604665994644165},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.15978017449378967},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.08278840780258179}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bigdata62323.2024.10825036","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bigdata62323.2024.10825036","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Big Data (BigData)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6200000047683716,"id":"https://metadata.un.org/sdg/7","display_name":"Affordable and clean energy"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320332359","display_name":"Office of Science","ror":"https://ror.org/00mmn6b08"},{"id":"https://openalex.org/F4320337506","display_name":"Advanced Scientific Computing Research","ror":"https://ror.org/0012c7r22"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1677182931","https://openalex.org/W1901129140","https://openalex.org/W1964231221","https://openalex.org/W1998331485","https://openalex.org/W1998706037","https://openalex.org/W2008802877","https://openalex.org/W2056370875","https://openalex.org/W2097517149","https://openalex.org/W2112410684","https://openalex.org/W2133665775","https://openalex.org/W2163532283","https://openalex.org/W2167400582","https://openalex.org/W2327216876","https://openalex.org/W2508457857","https://openalex.org/W2520016695","https://openalex.org/W2617128058","https://openalex.org/W2787894218","https://openalex.org/W2789171981","https://openalex.org/W2793146153","https://openalex.org/W2795777276","https://openalex.org/W2884436604","https://openalex.org/W2899172221","https://openalex.org/W2902857081","https://openalex.org/W2904263798","https://openalex.org/W2910683834","https://openalex.org/W2964335577","https://openalex.org/W2998779578","https://openalex.org/W3080821159","https://openalex.org/W3083622693","https://openalex.org/W3099334623","https://openalex.org/W3196224478","https://openalex.org/W3207346509","https://openalex.org/W4223970422","https://openalex.org/W4295312788","https://openalex.org/W4296142362","https://openalex.org/W4386076517","https://openalex.org/W4392909524","https://openalex.org/W4401609038","https://openalex.org/W6631190155","https://openalex.org/W6684084153","https://openalex.org/W6749271710","https://openalex.org/W6759001153","https://openalex.org/W6800524065"],"related_works":["https://openalex.org/W2371409811","https://openalex.org/W2956921597","https://openalex.org/W4394660771","https://openalex.org/W2070412032","https://openalex.org/W2188736150","https://openalex.org/W2804017673","https://openalex.org/W3185410177","https://openalex.org/W4293073787","https://openalex.org/W2768843469","https://openalex.org/W2614950993"],"abstract_inverted_index":{"Cone-beam":[0],"computed":[1,178],"tomography":[2,179],"(CBCT)":[3],"is":[4,98,162],"a":[5,43,49,90,99,111,134,163,237],"noninvasive":[6],"x-ray":[7,73],"imaging":[8,105],"technique":[9],"with":[10,31,42,110,222,253],"multiple":[11],"clinical":[12,56,100,127,261],"applications":[13,57],"(orthopedics,":[14],"dentistry,":[15],"radiation":[16,45,74],"therapy,":[17],"etc.).":[18],"These":[19],"systems":[20],"can":[21,79,273],"provide":[22],"sub-millimeter":[23],"resolution":[24],"in":[25,62,93,143,198,278],"images":[26,108,158],"of":[27,89,148,156,228],"high":[28],"diagnostic":[29],"quality":[30],"short":[32],"scanning":[33],"times.":[34],"However,":[35,107],"CBCT":[36,67,104,122,249,254,279],"scans":[37],"require":[38,65],"subjecting":[39],"the":[40,76,86,154,170,190,216,226,234,244,276,281,288,293,297,309],"patient":[41],"sufficient":[44],"dose":[46,113,259],"to":[47,72,102,195,219,257,284,287],"obtain":[48],"high-quality":[50],"image.":[51],"Although":[52],"relatively":[53],"low,":[54],"some":[55],"such":[58],"as":[59,207],"image":[60,123],"guidance":[61],"radiotherapy":[63],"(IGRT)":[64],"obtaining":[66],"daily.":[68],"This":[69],"repeated":[70],"exposure":[71],"outside":[75],"treatment":[77],"volume":[78],"have":[80,115,132],"detrimental":[81],"effects":[82],"and":[83,118,186,239,262,270,301,305],"may":[84],"increase":[85],"lifetime":[87],"risk":[88],"secondary":[91],"malignancy":[92],"younger":[94],"patients.":[95],"Hence,":[96],"there":[97],"need":[101],"reduce":[103,196,275],"dose.":[106],"produced":[109],"reduced":[112],"often":[114],"greater":[116],"noise":[117,141,197,277],"artifacts":[119],"which":[120,161],"deteriorate":[121],"quality,":[124],"reducing":[125],"their":[126],"efficacy.":[128],"Deep":[129],"learning-based":[130],"methods":[131,150],"become":[133],"popular":[135],"choice":[136],"showing":[137],"impressive":[138],"performance":[139],"for":[140,159,166,176,303],"reduction":[142],"low-dose":[144,289],"CBCT.":[145],"The":[146],"success":[147],"these":[149],"critically":[151],"depends":[152],"on":[153],"availability":[155],"paired":[157,184],"training":[160],"major":[164],"obstacle":[165],"most":[167],"applications.":[168],"Recently,":[169],"Noise2Inverse":[171,191,217],"method":[172,192,218],"was":[173,193],"designed":[174],"specifically":[175],"denoising":[177],"(CT)":[180],"data":[181,255],"without":[182],"requiring":[183,225],"noisy":[185],"clean":[187],"images.":[188,210],"While":[189],"shown":[194],"challenging":[199],"real-world":[200],"experimental":[201],"datasets,":[202],"it":[203],"processes":[204],"3D-CT":[205],"volumes":[206,224],"individual":[208],"2D":[209,238,269,310],"In":[211],"this":[212],"work,":[213],"we":[214],"extend":[215],"work":[220],"directly":[221],"3D-CBCT":[223],"use":[227],"high-end":[229],"HPC":[230],"resources.":[231],"We":[232],"compare":[233],"results":[235,265],"between":[236],"3D":[240,246,271,294],"UNet++":[241],"model":[242,295],"utilizing":[243],"ICASSP-2024":[245],"Low":[247],"Dose":[248],"Grand":[250],"Challenge":[251],"dataset":[252],"corresponding":[256],"two":[258],"levels,":[260],"low-dose.":[263],"Experimental":[264],"show":[266],"that":[267],"both":[268],"models":[272],"significantly":[274],"increasing":[280],"SSIM":[282,298],"up":[283],"148.05%":[285],"compared":[286],"FDK":[290],"reconstruction.":[291],"Furthermore,":[292],"improves":[296],"by":[299],"0.26%":[300],"1.46%":[302],"clinical-":[304],"low-dose,":[306],"respectively,":[307],"over":[308],"model.":[311]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}
