{"id":"https://openalex.org/W2584834695","doi":"https://doi.org/10.1109/bigdata.2016.7840721","title":"Lazer: Distributed memory-efficient assembly of large-scale genomes","display_name":"Lazer: Distributed memory-efficient assembly of large-scale genomes","publication_year":2016,"publication_date":"2016-12-01","ids":{"openalex":"https://openalex.org/W2584834695","doi":"https://doi.org/10.1109/bigdata.2016.7840721","mag":"2584834695"},"language":"en","primary_location":{"id":"doi:10.1109/bigdata.2016.7840721","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bigdata.2016.7840721","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE International Conference on Big Data (Big Data)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038227075","display_name":"S.C. Goswami","orcid":"https://orcid.org/0000-0002-7519-524X"},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sayan Goswami","raw_affiliation_strings":["School of Electrical Engineering & Computer Science, Louisiana State University"],"affiliations":[{"raw_affiliation_string":"School of Electrical Engineering & Computer Science, Louisiana State University","institution_ids":["https://openalex.org/I121820613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007929301","display_name":"Arghya Das","orcid":"https://orcid.org/0000-0003-0989-2175"},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arghya Kusum Das","raw_affiliation_strings":["School of Electrical Engineering & Computer Science, Louisiana State University"],"affiliations":[{"raw_affiliation_string":"School of Electrical Engineering & Computer Science, Louisiana State University","institution_ids":["https://openalex.org/I121820613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064959930","display_name":"Richard Platania","orcid":"https://orcid.org/0000-0002-2761-4729"},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard Platania","raw_affiliation_strings":["School of Electrical Engineering & Computer Science, Louisiana State University"],"affiliations":[{"raw_affiliation_string":"School of Electrical Engineering & Computer Science, Louisiana State University","institution_ids":["https://openalex.org/I121820613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103148122","display_name":"Kisung Lee","orcid":"https://orcid.org/0000-0003-4367-4374"},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kisung Lee","raw_affiliation_strings":["School of Electrical Engineering & Computer Science, Louisiana State University"],"affiliations":[{"raw_affiliation_string":"School of Electrical Engineering & Computer Science, Louisiana State University","institution_ids":["https://openalex.org/I121820613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079637252","display_name":"Seung\u2010Jong Park","orcid":"https://orcid.org/0000-0001-7821-7793"},"institutions":[{"id":"https://openalex.org/I121820613","display_name":"Louisiana State University","ror":"https://ror.org/05ect4e57","country_code":"US","type":"education","lineage":["https://openalex.org/I121820613"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seung-Jong Park","raw_affiliation_strings":["School of Electrical Engineering & Computer Science, Louisiana State University"],"affiliations":[{"raw_affiliation_string":"School of Electrical Engineering & Computer Science, Louisiana State University","institution_ids":["https://openalex.org/I121820613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5038227075"],"corresponding_institution_ids":["https://openalex.org/I121820613"],"apc_list":null,"apc_paid":null,"fwci":0.6669,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.74347795,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"2","issue":null,"first_page":"1171","last_page":"1181"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9876000285148621,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.98089998960495,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.7757843732833862},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7605400085449219},{"id":"https://openalex.org/keywords/de-bruijn-sequence","display_name":"De Bruijn sequence","score":0.5464504957199097},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.5129558444023132},{"id":"https://openalex.org/keywords/throughput","display_name":"Throughput","score":0.507782518863678},{"id":"https://openalex.org/keywords/parallel-computing","display_name":"Parallel computing","score":0.5014369487762451},{"id":"https://openalex.org/keywords/distributed-memory","display_name":"Distributed memory","score":0.4783210754394531},{"id":"https://openalex.org/keywords/de-bruijn-graph","display_name":"De Bruijn graph","score":0.4650735855102539},{"id":"https://openalex.org/keywords/sequence-assembly","display_name":"Sequence assembly","score":0.45165809988975525},{"id":"https://openalex.org/keywords/distributed-computing","display_name":"Distributed computing","score":0.40737301111221313},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.30039411783218384},{"id":"https://openalex.org/keywords/shared-memory","display_name":"Shared memory","score":0.22975388169288635},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21235081553459167},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.11939197778701782},{"id":"https://openalex.org/keywords/wireless","display_name":"Wireless","score":0.11633756756782532},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.09836292266845703},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.0818747878074646},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.07759454846382141}],"concepts":[{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.7757843732833862},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7605400085449219},{"id":"https://openalex.org/C170320093","wikidata":"https://www.wikidata.org/wiki/Q1953457","display_name":"De Bruijn sequence","level":2,"score":0.5464504957199097},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5129558444023132},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.507782518863678},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.5014369487762451},{"id":"https://openalex.org/C91481028","wikidata":"https://www.wikidata.org/wiki/Q1054686","display_name":"Distributed memory","level":3,"score":0.4783210754394531},{"id":"https://openalex.org/C20218877","wikidata":"https://www.wikidata.org/wiki/Q3066095","display_name":"De Bruijn graph","level":3,"score":0.4650735855102539},{"id":"https://openalex.org/C18949551","wikidata":"https://www.wikidata.org/wiki/Q740578","display_name":"Sequence assembly","level":5,"score":0.45165809988975525},{"id":"https://openalex.org/C120314980","wikidata":"https://www.wikidata.org/wiki/Q180634","display_name":"Distributed computing","level":1,"score":0.40737301111221313},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.30039411783218384},{"id":"https://openalex.org/C133875982","wikidata":"https://www.wikidata.org/wiki/Q764810","display_name":"Shared memory","level":2,"score":0.22975388169288635},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21235081553459167},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.11939197778701782},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.11633756756782532},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.09836292266845703},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0818747878074646},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.07759454846382141},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/bigdata.2016.7840721","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bigdata.2016.7840721","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE International Conference on Big Data (Big Data)","raw_type":"proceedings-article"},{"id":"pmh:oai:repository.lsu.edu:eecs_pubs-3565","is_oa":false,"landing_page_url":"https://repository.lsu.edu/eecs_pubs/2563","pdf_url":null,"source":{"id":"https://openalex.org/S4210169993","display_name":"Civil War Book Review","issn_l":"1528-6592","issn":["1528-6592"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4310315936","host_organization_name":"Louisiana State University","host_organization_lineage":["https://openalex.org/P4310315936"],"host_organization_lineage_names":["Louisiana State University"],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Faculty Publications","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1966822396","https://openalex.org/W1984971730","https://openalex.org/W2033292629","https://openalex.org/W2055343951","https://openalex.org/W2060380866","https://openalex.org/W2084134542","https://openalex.org/W2102532874","https://openalex.org/W2105191441","https://openalex.org/W2110392562","https://openalex.org/W2111071896","https://openalex.org/W2113679889","https://openalex.org/W2121911035","https://openalex.org/W2131062488","https://openalex.org/W2158468565","https://openalex.org/W2160969485","https://openalex.org/W2179933869","https://openalex.org/W2213505663","https://openalex.org/W2216435802","https://openalex.org/W2604216025","https://openalex.org/W6679633611","https://openalex.org/W6735920216"],"related_works":["https://openalex.org/W2562683361","https://openalex.org/W3087469195","https://openalex.org/W2354744388","https://openalex.org/W3125399386","https://openalex.org/W2949121831","https://openalex.org/W3215786367","https://openalex.org/W2991626973","https://openalex.org/W4387083702","https://openalex.org/W4318940746","https://openalex.org/W2133531097"],"abstract_inverted_index":{"Genome":[0],"sequencing":[1],"technology":[2],"has":[3],"witnessed":[4],"tremendous":[5],"progress":[6],"in":[7,19,22,84,102,112,131,138],"terms":[8],"of":[9,25,35,51,125],"throughput":[10],"as":[11,13,93],"well":[12],"cost":[14],"per":[15],"base":[16],"pair,":[17],"resulting":[18],"an":[20],"explosion":[21],"the":[23,76,81,85],"size":[24],"data.":[26],"Consequently,":[27],"typical":[28],"sequence":[29],"assembly":[30],"tools":[31],"demand":[32],"a":[33,58,118],"lot":[34],"processing":[36],"power":[37],"and":[38,40,65,79,105,134],"memory":[39,66],"are":[41],"unable":[42],"to":[43,109],"assemble":[44,89,117],"big":[45],"datasets":[46],"unless":[47],"run":[48],"on":[49,98,128,135],"hundreds":[50],"nodes.":[52],"In":[53],"this":[54],"paper,":[55],"we":[56,87],"present":[57],"distributed":[59],"assembler":[60],"that":[61],"achieves":[62],"both":[63],"scalability":[64],"efficiency":[67],"by":[68],"using":[69],"partitioned":[70],"de":[71],"Bruijn":[72],"graphs.":[73],"By":[74],"enhancing":[75],"memory-to-disk":[77],"swapping":[78],"reducing":[80],"network":[82],"communication":[83],"cluster,":[86],"can":[88],"large":[90],"sequences":[91],"such":[92],"human":[94],"genomes":[95],"(452":[96],"GB)":[97],"just":[99],"two":[100],"nodes":[101,111,130,137],"14.5":[103],"hours,":[104],"also":[106,116],"scale":[107],"up":[108],"128":[110,136],"23":[113],"minutes.":[114],"We":[115],"synthetic":[119],"wheat":[120],"genome":[121],"with":[122],"1.1":[123],"TB":[124],"raw":[126],"reads":[127],"8":[129],"18.5":[132],"hours":[133],"1.25":[139],"hours.":[140]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}