{"id":"https://openalex.org/W1988280752","doi":"https://doi.org/10.1109/bibmw.2012.6470326","title":"Protein secondary structure prediction using support vector machines and a codon encoding scheme","display_name":"Protein secondary structure prediction using support vector machines and a codon encoding scheme","publication_year":2012,"publication_date":"2012-10-01","ids":{"openalex":"https://openalex.org/W1988280752","doi":"https://doi.org/10.1109/bibmw.2012.6470326","mag":"1988280752"},"language":"en","primary_location":{"id":"doi:10.1109/bibmw.2012.6470326","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2012.6470326","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002302902","display_name":"Masood Zamani","orcid":null},"institutions":[{"id":"https://openalex.org/I79817857","display_name":"University of Guelph","ror":"https://ror.org/01r7awg59","country_code":"CA","type":"education","lineage":["https://openalex.org/I79817857"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Masood Zamani","raw_affiliation_strings":["School of Computer Science, University of Guelph, Guelph, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Guelph, Guelph, Canada","institution_ids":["https://openalex.org/I79817857"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053492737","display_name":"Stefan C. Kremer","orcid":"https://orcid.org/0000-0002-3667-4379"},"institutions":[{"id":"https://openalex.org/I79817857","display_name":"University of Guelph","ror":"https://ror.org/01r7awg59","country_code":"CA","type":"education","lineage":["https://openalex.org/I79817857"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Stefan C. Kremer","raw_affiliation_strings":["School of Computer Science, University of Guelph, Guelph, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Guelph, Guelph, Canada","institution_ids":["https://openalex.org/I79817857"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I79817857"],"apc_list":null,"apc_paid":null,"fwci":1.9075,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.84403417,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"7","issue":null,"first_page":"22","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/encoding","display_name":"Encoding (memory)","score":0.8011819124221802},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5796846151351929},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5482200384140015},{"id":"https://openalex.org/keywords/curse-of-dimensionality","display_name":"Curse of dimensionality","score":0.524873673915863},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.4474857449531555},{"id":"https://openalex.org/keywords/synonymous-substitution","display_name":"Synonymous substitution","score":0.4472346603870392},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.43394654989242554},{"id":"https://openalex.org/keywords/binary-number","display_name":"Binary number","score":0.42257726192474365},{"id":"https://openalex.org/keywords/codon-usage-bias","display_name":"Codon usage bias","score":0.4146312475204468},{"id":"https://openalex.org/keywords/computation","display_name":"Computation","score":0.4115198254585266},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.39874136447906494},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3666515350341797},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.348616361618042},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.27994364500045776},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.26178550720214844},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.22858670353889465},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22558435797691345},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.19020891189575195},{"id":"https://openalex.org/keywords/arithmetic","display_name":"Arithmetic","score":0.1124582588672638}],"concepts":[{"id":"https://openalex.org/C125411270","wikidata":"https://www.wikidata.org/wiki/Q18653","display_name":"Encoding (memory)","level":2,"score":0.8011819124221802},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5796846151351929},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5482200384140015},{"id":"https://openalex.org/C111030470","wikidata":"https://www.wikidata.org/wiki/Q1430460","display_name":"Curse of dimensionality","level":2,"score":0.524873673915863},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4474857449531555},{"id":"https://openalex.org/C138025448","wikidata":"https://www.wikidata.org/wiki/Q7662597","display_name":"Synonymous substitution","level":5,"score":0.4472346603870392},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.43394654989242554},{"id":"https://openalex.org/C48372109","wikidata":"https://www.wikidata.org/wiki/Q3913","display_name":"Binary number","level":2,"score":0.42257726192474365},{"id":"https://openalex.org/C87253356","wikidata":"https://www.wikidata.org/wiki/Q1106472","display_name":"Codon usage bias","level":4,"score":0.4146312475204468},{"id":"https://openalex.org/C45374587","wikidata":"https://www.wikidata.org/wiki/Q12525525","display_name":"Computation","level":2,"score":0.4115198254585266},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.39874136447906494},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3666515350341797},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.348616361618042},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.27994364500045776},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.26178550720214844},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22858670353889465},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22558435797691345},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.19020891189575195},{"id":"https://openalex.org/C94375191","wikidata":"https://www.wikidata.org/wiki/Q11205","display_name":"Arithmetic","level":1,"score":0.1124582588672638}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibmw.2012.6470326","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2012.6470326","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W2169610","https://openalex.org/W1491040459","https://openalex.org/W1499450468","https://openalex.org/W1506812273","https://openalex.org/W1533153109","https://openalex.org/W1537662695","https://openalex.org/W1602492977","https://openalex.org/W1606410455","https://openalex.org/W1974441870","https://openalex.org/W1981132436","https://openalex.org/W1985818354","https://openalex.org/W2008708467","https://openalex.org/W2013734705","https://openalex.org/W2024035237","https://openalex.org/W2027837654","https://openalex.org/W2035066314","https://openalex.org/W2041369927","https://openalex.org/W2076796998","https://openalex.org/W2087894810","https://openalex.org/W2092822846","https://openalex.org/W2093989924","https://openalex.org/W2095450147","https://openalex.org/W2100890997","https://openalex.org/W2104972430","https://openalex.org/W2106612397","https://openalex.org/W2119423166","https://openalex.org/W2119764329","https://openalex.org/W2122945697","https://openalex.org/W2138929157","https://openalex.org/W2147905080","https://openalex.org/W2148557779","https://openalex.org/W2153187042","https://openalex.org/W2153635508","https://openalex.org/W2156798505","https://openalex.org/W4239186484","https://openalex.org/W6600089577","https://openalex.org/W6631881766"],"related_works":["https://openalex.org/W2063135364","https://openalex.org/W1951333111","https://openalex.org/W2470001062","https://openalex.org/W2070163065","https://openalex.org/W2116571730","https://openalex.org/W1981728009","https://openalex.org/W1536760631","https://openalex.org/W2539510218","https://openalex.org/W1965233192","https://openalex.org/W2592510355"],"abstract_inverted_index":{"In":[0,64],"this":[1],"study,":[2],"we":[3],"evaluate":[4],"the":[5,29,65,76,79,106,125,154,159,165,177,184,188,192,202,210,230],"performance":[6,104],"of":[7,28,37,78,84,105,124,158,205,213,235],"a":[8,15,85],"protein":[9,60,94,133,168],"secondary":[10,46],"structure":[11,47,62],"prediction":[12,48,126,141,189],"model":[13,108,190],"using":[14,128,224],"new":[16],"amino":[17,206],"acid":[18,207],"\"codon\"":[19],"encoding":[20,32,40,81,89,131,178,193,218],"inspired":[21],"by":[22],"genetic":[23,197],"codon":[24,31,80,198,217],"mappings.":[25],"The":[26,103,118,136,173,216],"dimensionality":[27],"binary":[30,69],"is":[33,49,109,180,194,219],"less":[34,43],"than":[35],"that":[36,83],"an":[38,50,100,129],"orthogonal":[39,88,130],"which":[41,200],"requires":[42],"computations.":[44],"Protein":[45],"important":[51],"step":[52],"for":[53,59,99],"machine":[54],"learning":[55,227],"techniques":[56],"ultimately":[57],"applied":[58],"3D":[61],"prediction.":[63],"proposed":[66,160],"model,":[67],"one-stage":[68],"support":[70],"vector":[71],"machines":[72],"are":[73,90,120,150,162,201],"employed,":[74],"and":[75,96,132,170,232],"efficiency":[77],"to":[82,112,182,221],"commonly":[86],"used":[87],"compared":[91,121],"without":[92],"incorporating":[93,167],"evolutionary":[95,171,185],"structural":[97,233],"information":[98,186],"unbiased":[101],"comparison.":[102],"classification":[107,156],"measured":[110],"according":[111],"Q3and":[113],"segment":[114],"overlap":[115],"(SOV)":[116],"scores.":[117],"scores":[119,146,157],"with":[122,164,229],"those":[123],"methods":[127,166],"sequence":[134,148],"profiles.":[135],"experimental":[137,174],"results":[138],"indicate":[139],"higher":[140],"accuracy":[142],"based":[143,195],"on":[144,196],"Q3SOV":[145],"when":[147],"profiles":[149,231],"not":[151],"used.":[152],"Also,":[153],"relative":[155],"method":[161],"comparable":[163],"global":[169],"information.":[172],"result":[175],"implies":[176],"scheme":[179],"able":[181],"integrate":[183],"into":[187],"since":[191],"mappings":[199],"building":[203],"blocks":[204],"formations":[208],"at":[209],"primary":[211],"level":[212],"biological":[214],"processes.":[215],"worthwhile":[220],"be":[222],"investigated":[223],"more":[225],"complex":[226],"architectures":[228],"properties":[234],"proteins.":[236]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}