{"id":"https://openalex.org/W2076794386","doi":"https://doi.org/10.1109/bibmw.2012.6470280","title":"Assemblable project formulation for drug target discovery","display_name":"Assemblable project formulation for drug target discovery","publication_year":2012,"publication_date":"2012-10-01","ids":{"openalex":"https://openalex.org/W2076794386","doi":"https://doi.org/10.1109/bibmw.2012.6470280","mag":"2076794386"},"language":"en","primary_location":{"id":"doi:10.1109/bibmw.2012.6470280","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2012.6470280","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017682090","display_name":"Byung\u2010Cheol Kim","orcid":"https://orcid.org/0000-0003-1226-8998"},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Byung-Cheol Kim","raw_affiliation_strings":["Medicinal Bioconvergence Research Center, Seoul National University, Suwon, South Korea","Medicinal Bioconvergence Research Center, Seoul National University, Suwon 443-270, Republic of Korea#TAB#"],"affiliations":[{"raw_affiliation_string":"Medicinal Bioconvergence Research Center, Seoul National University, Suwon, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Medicinal Bioconvergence Research Center, Seoul National University, Suwon 443-270, Republic of Korea#TAB#","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100429324","display_name":"Sung\u2010Hoon Kim","orcid":"https://orcid.org/0000-0002-1570-3230"},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sunghoon Kim","raw_affiliation_strings":["WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, South Korea","WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul 151-742, Republic of Korea#TAB#"],"affiliations":[{"raw_affiliation_string":"WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, South Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"WCU Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul 151-742, Republic of Korea#TAB#","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5017682090"],"corresponding_institution_ids":["https://openalex.org/I139264467"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13688584,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":null,"first_page":"954","last_page":"955"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/standardization","display_name":"Standardization","score":0.7763121128082275},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7622188329696655},{"id":"https://openalex.org/keywords/component","display_name":"Component (thermodynamics)","score":0.7067817449569702},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.5573333501815796},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5257169604301453},{"id":"https://openalex.org/keywords/key","display_name":"Key (lock)","score":0.4935523271560669},{"id":"https://openalex.org/keywords/variety","display_name":"Variety (cybernetics)","score":0.47990214824676514},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.36202794313430786},{"id":"https://openalex.org/keywords/risk-analysis","display_name":"Risk analysis (engineering)","score":0.35799330472946167},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.19804871082305908}],"concepts":[{"id":"https://openalex.org/C188087704","wikidata":"https://www.wikidata.org/wiki/Q369577","display_name":"Standardization","level":2,"score":0.7763121128082275},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7622188329696655},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.7067817449569702},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5573333501815796},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5257169604301453},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.4935523271560669},{"id":"https://openalex.org/C136197465","wikidata":"https://www.wikidata.org/wiki/Q1729295","display_name":"Variety (cybernetics)","level":2,"score":0.47990214824676514},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.36202794313430786},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.35799330472946167},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.19804871082305908},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibmw.2012.6470280","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2012.6470280","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1978839489","https://openalex.org/W1991845461","https://openalex.org/W2109331600","https://openalex.org/W2803560454"],"related_works":["https://openalex.org/W2378767206","https://openalex.org/W1540871478","https://openalex.org/W328308450","https://openalex.org/W282641168","https://openalex.org/W2376963063","https://openalex.org/W2066396794","https://openalex.org/W2366734808","https://openalex.org/W2002476357","https://openalex.org/W2391444248","https://openalex.org/W2982428536"],"abstract_inverted_index":{"An":[0],"ever":[1],"increasing":[2],"hardness":[3],"of":[4,25,56,110,151,154,163],"drug":[5,35,58],"approval":[6],"processes":[7,112],"and":[8,19,28,113,172,207,224,231],"criteria":[9],"leads":[10],"to":[11,15,54,61,82,84,101,216],"a":[12,23,34,48,52,63,117,139,204,229],"systemic":[13],"approach":[14,95],"novel":[16,57],"target":[17,36,64],"identification":[18],"validation.":[20],"This":[21,115],"involves":[22],"variety":[24],"methods,":[26],"tools,":[27],"related":[29],"data":[30,142],"which":[31,68,189],"collectively":[32],"pre-validate":[33],"in":[37,67,72,96,228],"multiple":[38],"aspects":[39],"so":[40],"that":[41,127],"it":[42,212],"can":[43,130,190,200],"finally":[44],"be":[45,191,201],"approved":[46],"as":[47,90,159,193],"new":[49],"drug.":[50],"Thus,":[51],"key":[53],"success":[55],"targets":[59],"is":[60,100],"establish":[62],"production":[65],"framework":[66,157],"heterogeneous":[69],"methodologies":[70],"work":[71],"concert":[73],"with":[74],"one":[75],"another.":[76],"Then,":[77],"the":[78,97,128,132,149,177,184,226],"problem":[79],"boils":[80],"down":[81],"how":[83],"make":[85],"those":[86,111],"diverse":[87],"technologies":[88],"function":[89],"an":[91],"organic":[92],"whole.":[93],"Our":[94],"first":[98],"place":[99],"tightly":[102],"couple":[103],"them":[104,137],"together":[105],"based":[106],"on":[107,148,176],"tangible":[108],"output":[109],"methods.":[114],"requires":[116],"quantitatively":[118],"standardized":[119],"specification":[120,129],"for":[121,213],"each":[122,152,198],"component":[123,199],"because":[124],"we":[125,180,209],"expect":[126],"reveal":[131],"precise":[133],"link":[134],"point":[135],"between":[136],"at":[138],"technique":[140],"or":[141],"level.":[143],"We":[144],"are":[145],"now":[146],"working":[147],"standardization":[150],"part":[153],"our":[155],"own":[156],"such":[158],"feasibility":[160],"test,":[161],"mode":[162],"action,":[164],"clinical":[165],"validation,":[166],"biomarker,":[167],"assay,":[168],"lead,":[169],"disease":[170],"model,":[171],"crystal":[173],"structure.":[174],"Based":[175],"detailed":[178],"specification,":[179],"will":[181],"find":[182],"out":[183],"common":[185],"and/or":[186],"compatible":[187],"elements":[188],"used":[192],"junctions.":[194],"Using":[195],"these":[196],"junctions,":[197],"assembled":[202],"into":[203],"single":[205],"conglomerate":[206],"then":[208],"could":[210],"landscape":[211],"various":[214],"stakeholders":[215],"intuitively":[217],"share":[218],"up-to-date":[219],"progress":[220],"status,":[221],"identify":[222],"bottlenecks,":[223],"resolve":[225],"problems":[227],"cooperative":[230],"responsive":[232],"manner.":[233]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}