{"id":"https://openalex.org/W2028435699","doi":"https://doi.org/10.1109/bibmw.2011.6112397","title":"Analysis of relevant physicochemical properties in obligate and non-obligate protein-protein interactions","display_name":"Analysis of relevant physicochemical properties in obligate and non-obligate protein-protein interactions","publication_year":2011,"publication_date":"2011-11-01","ids":{"openalex":"https://openalex.org/W2028435699","doi":"https://doi.org/10.1109/bibmw.2011.6112397","mag":"2028435699"},"language":"en","primary_location":{"id":"doi:10.1109/bibmw.2011.6112397","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2011.6112397","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027262289","display_name":"Mina Maleki","orcid":"https://orcid.org/0000-0003-4723-3058"},"institutions":[{"id":"https://openalex.org/I74413500","display_name":"University of Windsor","ror":"https://ror.org/01gw3d370","country_code":"CA","type":"education","lineage":["https://openalex.org/I74413500"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. Maleki","raw_affiliation_strings":["School of Computer Science, University of Windsor, Windsor, ONT, Canada","School of Computer Science, University of Windsor, 401 Sunset Ave, Windsor, ON N9B 3P4, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Windsor, Windsor, ONT, Canada","institution_ids":["https://openalex.org/I74413500"]},{"raw_affiliation_string":"School of Computer Science, University of Windsor, 401 Sunset Ave, Windsor, ON N9B 3P4, Canada","institution_ids":["https://openalex.org/I74413500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046615575","display_name":"Md. Mominul Aziz","orcid":null},"institutions":[{"id":"https://openalex.org/I74413500","display_name":"University of Windsor","ror":"https://ror.org/01gw3d370","country_code":"CA","type":"education","lineage":["https://openalex.org/I74413500"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. M. Aziz","raw_affiliation_strings":["School of Computer Science, University of Windsor, Windsor, ONT, Canada","School of Computer Science, University of Windsor, 401 Sunset Ave, Windsor, ON N9B 3P4, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Windsor, Windsor, ONT, Canada","institution_ids":["https://openalex.org/I74413500"]},{"raw_affiliation_string":"School of Computer Science, University of Windsor, 401 Sunset Ave, Windsor, ON N9B 3P4, Canada","institution_ids":["https://openalex.org/I74413500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040978295","display_name":"Luis Rueda","orcid":"https://orcid.org/0000-0001-7988-2058"},"institutions":[{"id":"https://openalex.org/I74413500","display_name":"University of Windsor","ror":"https://ror.org/01gw3d370","country_code":"CA","type":"education","lineage":["https://openalex.org/I74413500"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"L. Rueda","raw_affiliation_strings":["School of Computer Science, University of Windsor, Windsor, ONT, Canada","School of Computer Science, University of Windsor, 401 Sunset Ave, Windsor, ON N9B 3P4, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, University of Windsor, Windsor, ONT, Canada","institution_ids":["https://openalex.org/I74413500"]},{"raw_affiliation_string":"School of Computer Science, University of Windsor, 401 Sunset Ave, Windsor, ON N9B 3P4, Canada","institution_ids":["https://openalex.org/I74413500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I74413500"],"apc_list":null,"apc_paid":null,"fwci":4.9706,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.9449603,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"345","last_page":"351"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.996399998664856,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obligate","display_name":"Obligate","score":0.9148262739181519},{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.5942820310592651},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.5589569211006165},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5420831441879272},{"id":"https://openalex.org/keywords/amino-acid","display_name":"Amino acid","score":0.5185247659683228},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42338189482688904},{"id":"https://openalex.org/keywords/redundancy","display_name":"Redundancy (engineering)","score":0.4185003340244293},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3767321705818176},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.29738128185272217},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2146751880645752}],"concepts":[{"id":"https://openalex.org/C24990904","wikidata":"https://www.wikidata.org/wiki/Q7075144","display_name":"Obligate","level":2,"score":0.9148262739181519},{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.5942820310592651},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.5589569211006165},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5420831441879272},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.5185247659683228},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42338189482688904},{"id":"https://openalex.org/C152124472","wikidata":"https://www.wikidata.org/wiki/Q1204361","display_name":"Redundancy (engineering)","level":2,"score":0.4185003340244293},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3767321705818176},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.29738128185272217},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2146751880645752},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibmw.2011.6112397","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2011.6112397","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7599999904632568,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W174644880","https://openalex.org/W1585607520","https://openalex.org/W1792865908","https://openalex.org/W1840341001","https://openalex.org/W1926568554","https://openalex.org/W1975888060","https://openalex.org/W1976754976","https://openalex.org/W1984694072","https://openalex.org/W1987749411","https://openalex.org/W2025120281","https://openalex.org/W2031772330","https://openalex.org/W2045501270","https://openalex.org/W2046368494","https://openalex.org/W2053502852","https://openalex.org/W2056034415","https://openalex.org/W2071704671","https://openalex.org/W2073189519","https://openalex.org/W2075770210","https://openalex.org/W2089355842","https://openalex.org/W2101362041","https://openalex.org/W2118507670","https://openalex.org/W2122586474","https://openalex.org/W2130123090","https://openalex.org/W2130479394","https://openalex.org/W2131987814","https://openalex.org/W2138735135","https://openalex.org/W2138771217","https://openalex.org/W2141826465","https://openalex.org/W2154053567","https://openalex.org/W2158100564","https://openalex.org/W2161506293","https://openalex.org/W2332240239","https://openalex.org/W2407208114","https://openalex.org/W4233300082","https://openalex.org/W6713616416"],"related_works":["https://openalex.org/W3047334771","https://openalex.org/W2912319656","https://openalex.org/W4298089146","https://openalex.org/W4235896803","https://openalex.org/W2956098766","https://openalex.org/W1557435294","https://openalex.org/W1954506205","https://openalex.org/W2140124925","https://openalex.org/W3015830444","https://openalex.org/W2048549326"],"abstract_inverted_index":{"Identification":[0],"and":[1,35,40,64,137,145],"analysis":[2],"of":[3,5,17,73,81,83,92,120],"types":[4,72],"protein-protein":[6],"interactions":[7],"(PPI)":[8],"is":[9,50],"an":[10],"important":[11],"problem":[12],"in":[13,21,25,89],"molecular":[14],"biology":[15],"because":[16],"its":[18],"key":[19],"role":[20],"many":[22],"biological":[23],"processes":[24],"living":[26],"cells.":[27],"In":[28],"this":[29],"paper,":[30],"we":[31],"focus":[32,59],"on":[33,52,60,97,107],"obligate":[34,144],"non-obligate":[36,146],"complexes,":[37],"their":[38],"prediction":[39,76,118],"analysis.":[41],"We":[42],"propose":[43],"a":[44],"feature":[45,124],"selection":[46,125],"scheme":[47],"called":[48],"MRMRprowhich":[49],"based":[51],"Minimum":[53],"Redundancy":[54],"Maximum":[55],"Relevance":[56],"(MRMR)":[57],"to":[58,67,104,141],"the":[61,90,117],"most":[62],"discriminative":[63],"relevant":[65,112],"properties":[66],"distinguish":[68,142],"between":[69,143],"these":[70],"two":[71,98],"complexes.":[74,94,147],"Our":[75,95],"approach":[77],"uses":[78],"desolvation":[79],"energies":[80],"pairs":[82],"atoms":[84],"or":[85],"amino":[86,130,139],"acids":[87,131,140],"present":[88],"interfaces":[91],"such":[93],"results":[96],"well-known":[99],"datasets":[100],"confirm":[101],"that":[102,128],"MRMRproleads":[103],"significant":[105],"improvements":[106],"performance":[108,119],"by":[109],"finding":[110],"more":[111,133],"features":[113],"for":[114],"prediction.":[115],"Furthermore,":[116],"our":[121],"biologically":[122],"guided":[123],"methods":[126],"demonstrate":[127],"hydrophobic":[129],"are":[132],"discriminating":[134],"than":[135],"hydrophilic":[136],"amphipathic":[138]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}