{"id":"https://openalex.org/W2118561360","doi":"https://doi.org/10.1109/bibmw.2010.5703927","title":"NWE: Node-weighted expansion for protein complex prediction using random walk distances","display_name":"NWE: Node-weighted expansion for protein complex prediction using random walk distances","publication_year":2010,"publication_date":"2010-12-01","ids":{"openalex":"https://openalex.org/W2118561360","doi":"https://doi.org/10.1109/bibmw.2010.5703927","mag":"2118561360"},"language":"en","primary_location":{"id":"doi:10.1109/bibmw.2010.5703927","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2010.5703927","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://catalog.lib.kyushu-u.ac.jp/opac_download_md/25714/2277_938.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035228232","display_name":"Osamu Maruyama","orcid":"https://orcid.org/0000-0002-5760-1507"},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Osamu Maruyama","raw_affiliation_strings":["Graduate School of System Life Sciences, Kyushu University, Fukuoka, Japan","Faculty of Mathematics and Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of System Life Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]},{"raw_affiliation_string":"Faculty of Mathematics and Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022841441","display_name":"Ayaka Chihara","orcid":null},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ayaka Chihara","raw_affiliation_strings":["Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan","Graduate School of Systems Life Sciences, Kyushu Univ., Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Systems Life Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]},{"raw_affiliation_string":"Graduate School of Systems Life Sciences, Kyushu Univ., Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I135598925"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"Suppl 1","first_page":"825","last_page":"826"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/node","display_name":"Node (physics)","score":0.7770960330963135},{"id":"https://openalex.org/keywords/random-walk","display_name":"Random walk","score":0.6166799664497375},{"id":"https://openalex.org/keywords/cluster","display_name":"Cluster (spacecraft)","score":0.5702347755432129},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5107758045196533},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5049822926521301},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.35620516538619995},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.33920422196388245},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.1902087926864624},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.17111000418663025},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.11963403224945068}],"concepts":[{"id":"https://openalex.org/C62611344","wikidata":"https://www.wikidata.org/wiki/Q1062658","display_name":"Node (physics)","level":2,"score":0.7770960330963135},{"id":"https://openalex.org/C121194460","wikidata":"https://www.wikidata.org/wiki/Q856741","display_name":"Random walk","level":2,"score":0.6166799664497375},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.5702347755432129},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5107758045196533},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5049822926521301},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.35620516538619995},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.33920422196388245},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.1902087926864624},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.17111000418663025},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11963403224945068},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/bibmw.2010.5703927","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibmw.2010.5703927","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)","raw_type":"proceedings-article"},{"id":"pmh:oai:catalog.lib.kyushu-u.ac.jp:2324/25714","is_oa":true,"landing_page_url":"http://hdl.handle.net/2324/25714","pdf_url":"https://catalog.lib.kyushu-u.ac.jp/opac_download_md/25714/2277_938.pdf","source":{"id":"https://openalex.org/S4306400832","display_name":"Kyushu University Institutional Repository (QIR) (Kyushu University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I135598925","host_organization_name":"Kyushu University","host_organization_lineage":["https://openalex.org/I135598925"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"S14(11)","raw_type":"journal article"},{"id":"pmh:oai:irdb.nii.ac.jp:01211:0005983100","is_oa":true,"landing_page_url":"https://hdl.handle.net/2324/25714","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proteome Science","raw_type":"journal article"}],"best_oa_location":{"id":"pmh:oai:catalog.lib.kyushu-u.ac.jp:2324/25714","is_oa":true,"landing_page_url":"http://hdl.handle.net/2324/25714","pdf_url":"https://catalog.lib.kyushu-u.ac.jp/opac_download_md/25714/2277_938.pdf","source":{"id":"https://openalex.org/S4306400832","display_name":"Kyushu University Institutional Repository (QIR) (Kyushu University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I135598925","host_organization_name":"Kyushu University","host_organization_lineage":["https://openalex.org/I135598925"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"S14(11)","raw_type":"journal article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2118561360.pdf","grobid_xml":"https://content.openalex.org/works/W2118561360.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1514107797","https://openalex.org/W1783384641","https://openalex.org/W1987363726","https://openalex.org/W1988496202","https://openalex.org/W2003798029","https://openalex.org/W2030006812","https://openalex.org/W2037036397","https://openalex.org/W2050721857","https://openalex.org/W2052652433","https://openalex.org/W2057793636","https://openalex.org/W2065304353","https://openalex.org/W2069153192","https://openalex.org/W2077943220","https://openalex.org/W2083255534","https://openalex.org/W2107067224","https://openalex.org/W2116117181","https://openalex.org/W2119359534","https://openalex.org/W2122964432","https://openalex.org/W2124166542","https://openalex.org/W2124354935","https://openalex.org/W2124821604","https://openalex.org/W2130687290","https://openalex.org/W2136850043","https://openalex.org/W2138003801","https://openalex.org/W2151176490","https://openalex.org/W2152495216","https://openalex.org/W2167869241","https://openalex.org/W2170344111","https://openalex.org/W6630727257"],"related_works":["https://openalex.org/W2051487156","https://openalex.org/W2073681303","https://openalex.org/W1597743604","https://openalex.org/W2038723108","https://openalex.org/W2317200988","https://openalex.org/W2033630974","https://openalex.org/W2325737604","https://openalex.org/W4297449606","https://openalex.org/W4245069437","https://openalex.org/W2367569662"],"abstract_inverted_index":{"In":[0,103],"this":[1,104],"work,":[2,105],"we":[3],"propose":[4],"a":[5,18,22,54,109],"protein":[6,45,94],"complex":[7,46],"prediction":[8],"method":[9,13,38],"based":[10],"on":[11],"the":[12,28,37,81,100,106,115,119,123,127],"of":[14,17,36,58,75,80,84,96,108,118,121],"node-weighted":[15],"expansion":[16],"cluster,":[19],"which":[20,61],"simulates":[21],"random":[23],"walk":[24],"with":[25,27,90],"restarts":[26],"cluster":[29],"whose":[30],"nodes":[31],"are":[32,86],"weighted.":[33],"Our":[34],"implementation":[35],"is":[39,62,111],"called":[40],"NWE":[41,51],"(Node-Weighted":[42],"Expansion":[43],"for":[44],"prediction).":[47],"We":[48],"have":[49],"applied":[50],"to":[52,113,126],"WI-PHI,":[53],"genome-wide":[55],"PPI":[56],"network":[57],"S.":[59,97],"cerevisiae,":[60],"obtained":[63,71],"by":[64,88],"integrating":[65],"various":[66],"heterogeneous":[67],"data":[68],"sources,":[69],"and":[70],"statistically":[72],"significant":[73],"clusters":[74,83],"proteins.":[76],"The":[77],"biological":[78],"significance":[79],"predicted":[82],"proteins":[85],"validated":[87],"comparison":[89],"manually":[91],"curated":[92],"heteromeric":[93],"complexes":[95],"cerevisiae":[98],"in":[99],"CYC2008":[101],"database.":[102],"weight":[107],"node":[110],"set":[112],"be":[114],"total":[116],"sum":[117],"weights":[120],"all":[122],"edges":[124],"adjoining":[125],"node.":[128]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}