{"id":"https://openalex.org/W7126057791","doi":"https://doi.org/10.1109/bibm66473.2025.11356864","title":"An Atlas of Electroencephalographic Infraslow Oscillation Features During Sleep in a Clinical Cohort","display_name":"An Atlas of Electroencephalographic Infraslow Oscillation Features During Sleep in a Clinical Cohort","publication_year":2025,"publication_date":"2025-12-15","ids":{"openalex":"https://openalex.org/W7126057791","doi":"https://doi.org/10.1109/bibm66473.2025.11356864"},"language":null,"primary_location":{"id":"doi:10.1109/bibm66473.2025.11356864","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm66473.2025.11356864","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5124289636","display_name":"Ella Tianjing Luo","orcid":null},"institutions":[{"id":"https://openalex.org/I4210088148","display_name":"New England School of Photography","ror":"https://ror.org/011na1r14","country_code":"US","type":"education","lineage":["https://openalex.org/I4210088148"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ella Tianjing Luo","raw_affiliation_strings":["The Winsor School,Boston,MA,USA"],"affiliations":[{"raw_affiliation_string":"The Winsor School,Boston,MA,USA","institution_ids":["https://openalex.org/I4210088148"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124295260","display_name":"Haoqi Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haoqi Sun","raw_affiliation_strings":["Beth Israel Deaconess Medical Center,Department of Neurology,Boston,MA,USA"],"affiliations":[{"raw_affiliation_string":"Beth Israel Deaconess Medical Center,Department of Neurology,Boston,MA,USA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124240171","display_name":"Tingying Helen Zeng","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tingying Helen Zeng","raw_affiliation_strings":["InnoBridge Institute,Cambridge,MA,USA"],"affiliations":[{"raw_affiliation_string":"InnoBridge Institute,Cambridge,MA,USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5124169695","display_name":"Elizaveta Tremsina","orcid":null},"institutions":[{"id":"https://openalex.org/I4210110987","display_name":"IIT@MIT","ror":"https://ror.org/01wp8zh54","country_code":"US","type":"facility","lineage":["https://openalex.org/I30771326","https://openalex.org/I4210110987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizaveta Tremsina","raw_affiliation_strings":["MIT,EECS,Cambridge,MA,USA"],"affiliations":[{"raw_affiliation_string":"MIT,EECS,Cambridge,MA,USA","institution_ids":["https://openalex.org/I4210110987"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5124289636"],"corresponding_institution_ids":["https://openalex.org/I4210088148"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.71367371,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"6731","last_page":"6737"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.38089999556541443,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10985","display_name":"Sleep and Wakefulness Research","score":0.38089999556541443,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.32749998569488525,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11456","display_name":"Neuroscience of respiration and sleep","score":0.07109999656677246,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polysomnography","display_name":"Polysomnography","score":0.6600000262260437},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.47360000014305115},{"id":"https://openalex.org/keywords/rhythm","display_name":"Rhythm","score":0.4345000088214874},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.366100013256073},{"id":"https://openalex.org/keywords/sleep","display_name":"Sleep (system call)","score":0.3564999997615814},{"id":"https://openalex.org/keywords/sleep-stages","display_name":"Sleep Stages","score":0.3504999876022339}],"concepts":[{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.6600000262260437},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.51910001039505},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.5167999863624573},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4975999891757965},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.47360000014305115},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.4345000088214874},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.366100013256073},{"id":"https://openalex.org/C2775841894","wikidata":"https://www.wikidata.org/wiki/Q4683692","display_name":"Sleep (system call)","level":2,"score":0.3564999997615814},{"id":"https://openalex.org/C2910364982","wikidata":"https://www.wikidata.org/wiki/Q35831","display_name":"Sleep Stages","level":4,"score":0.3504999876022339},{"id":"https://openalex.org/C110539466","wikidata":"https://www.wikidata.org/wiki/Q3964845","display_name":"Slow-wave sleep","level":3,"score":0.3490000069141388},{"id":"https://openalex.org/C2778439541","wikidata":"https://www.wikidata.org/wiki/Q7106412","display_name":"Oscillation (cell signaling)","level":2,"score":0.3479999899864197},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3050000071525574},{"id":"https://openalex.org/C2779320081","wikidata":"https://www.wikidata.org/wiki/Q246710","display_name":"Wakefulness","level":3,"score":0.28839999437332153},{"id":"https://openalex.org/C2983668108","wikidata":"https://www.wikidata.org/wiki/Q280453","display_name":"Spectral analysis","level":3,"score":0.28540000319480896},{"id":"https://openalex.org/C2776673561","wikidata":"https://www.wikidata.org/wiki/Q655357","display_name":"Atlas (anatomy)","level":2,"score":0.25690001249313354},{"id":"https://openalex.org/C2778013878","wikidata":"https://www.wikidata.org/wiki/Q646150","display_name":"Grey matter","level":4,"score":0.2517000138759613}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm66473.2025.11356864","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm66473.2025.11356864","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3389436060","display_name":null,"funder_award_id":"2014431","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7787280780","display_name":null,"funder_award_id":"R01NS102190,R01NS102574,R01NS107291,RF1AG064312,RF1NS120947,R01AG073410,R01HL161253,R01NS126282,R01AG073598","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306710","display_name":"Glenn Foundation for Medical Research","ror":"https://ror.org/02ebg5q27"},{"id":"https://openalex.org/F4320308417","display_name":"American Foundation for Aging Research","ror":"https://ror.org/000r61a05"},{"id":"https://openalex.org/F4320311624","display_name":"American Academy of Sleep Medicine","ror":"https://ror.org/0090hd978"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W211905087","https://openalex.org/W2049369164","https://openalex.org/W2103528520","https://openalex.org/W2130243088","https://openalex.org/W2163225965","https://openalex.org/W2278988702","https://openalex.org/W2641667423","https://openalex.org/W2767399804","https://openalex.org/W2895999528","https://openalex.org/W2905282471","https://openalex.org/W2982626951","https://openalex.org/W3205348781","https://openalex.org/W4406155654"],"related_works":[],"abstract_inverted_index":{"The":[0,98,152,183,195,214],"recent":[1],"discovery":[2],"of":[3,23,30,65,115,205],"infraslow":[4,132],"oscillations":[5],"(ISOs),":[6],"rhythmic":[7],"fluctuations":[8],"at":[9,211],"roughly":[10],"0.02":[11],"Hz,":[12,140,207],"has":[13],"been":[14],"increasingly":[15],"linked":[16],"to":[17,36,61,72,130],"critical":[18],"sleep":[19,96],"functions,":[20,27],"including":[21],"coordination":[22],"neural":[24],"activity,":[25],"autonomic":[26],"and":[28,38,107,121,143,162,227],"facilitation":[29],"glymphatic":[31],"clearance.":[32],"Given":[33],"their":[34],"relevance":[35],"aging":[37],"brain":[39],"health,":[40],"understanding":[41],"how":[42],"ISO":[43,66,135,153,173,184,192,196],"properties":[44],"evolve":[45],"across":[46,103],"the":[47,73,150,191],"adult":[48],"lifespan":[49],"remains":[50],"an":[51,63],"important":[52],"step":[53],"toward":[54],"establishing":[55],"normative":[56],"baselines.":[57],"Here,":[58],"we":[59],"aim":[60],"develop":[62],"atlas":[64,216],"features":[67],"that":[68,76],"are":[69],"publicly":[70],"available":[71],"research":[74,221],"community":[75],"enables":[77,217],"downstream":[78,220],"research.":[79],"Overnight":[80],"polysomnography":[81],"recordings":[82],"from":[83,88,138,165],"878":[84],"participants":[85],"were":[86,147],"selected":[87],"Human":[89],"Sleep":[90],"Project,":[91],"which":[92],"is":[93],"a":[94,113,203],"clinical":[95],"dataset.":[97],"patient":[99],"selection":[100],"was":[101],"balanced":[102],"four":[104],"age":[105,212],"groups":[106],"biological":[108],"sex.":[109],"We":[110],"first":[111],"extracted":[112],"timeseries":[114],"1/f":[116],"corrected":[117],"sigma-band":[118],"(11\u201315":[119],"Hz),":[120],"then":[122,163],"computed":[123],"its":[124],"spectrum":[125],"using":[126],"multi-taper":[127],"spectral":[128],"estimation":[129],"extract":[131],"fluctuations.":[133],"Relative":[134],"band":[136,154,174,193],"power":[137,146,155,175,186],"0.005-0.03":[139],"peak":[141,145,185,197],"frequency,":[142],"relative":[144],"included":[148],"in":[149],"atlas.":[151],"increased":[156],"until":[157],"early":[158],"adulthood,":[159],"remained":[160,199],"stable,":[161],"decreased":[164],"60":[166],"years":[167,181],"old":[168],"onward.":[169],"Females":[170],"exhibited":[171],"higher":[172],"than":[176],"males,":[177],"particularly":[178],"around":[179],"50-60":[180],"old.":[182],"had":[187],"similar":[188],"patterns":[189],"with":[190,202,208],"power.":[194],"frequency":[198],"largely":[200],"stable":[201],"median":[204],"0.011":[206],"minor":[209],"shifts":[210],"extremes.":[213],"resulting":[215],"multiple":[218],"future":[219],"opportunities,":[222],"such":[223],"as":[224],"medication":[225],"effect":[226],"outcome":[228],"prediction.":[229]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2026-01-30T00:00:00"}