{"id":"https://openalex.org/W7126056481","doi":"https://doi.org/10.1109/bibm66473.2025.11356414","title":"scDVCC:Deep Clustering of scRNA-Seq Based on Dual-View Contrastive Learning","display_name":"scDVCC:Deep Clustering of scRNA-Seq Based on Dual-View Contrastive Learning","publication_year":2025,"publication_date":"2025-12-15","ids":{"openalex":"https://openalex.org/W7126056481","doi":"https://doi.org/10.1109/bibm66473.2025.11356414"},"language":null,"primary_location":{"id":"doi:10.1109/bibm66473.2025.11356414","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm66473.2025.11356414","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5124196296","display_name":"Shudong Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shudong Wang","raw_affiliation_strings":["College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China","institution_ids":["https://openalex.org/I4210162190"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yue Song","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Song","raw_affiliation_strings":["College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China","institution_ids":["https://openalex.org/I4210162190"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015819673","display_name":"Wenhao Wu","orcid":"https://orcid.org/0000-0002-8511-743X"},"institutions":[{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenhao Wu","raw_affiliation_strings":["College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China","institution_ids":["https://openalex.org/I4210162190"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082780758","display_name":"Hengxiao Li","orcid":"https://orcid.org/0009-0002-9699-7169"},"institutions":[{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hengxiao Li","raw_affiliation_strings":["College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China","institution_ids":["https://openalex.org/I4210162190"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124297615","display_name":"Yulin Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yulin Zhang","raw_affiliation_strings":["College of Mathematics and Systems Science, Shandong University of Science and Technology,Qingdao,China"],"affiliations":[{"raw_affiliation_string":"College of Mathematics and Systems Science, Shandong University of Science and Technology,Qingdao,China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067844688","display_name":"Shanchen Pang","orcid":"https://orcid.org/0009-0007-5620-0609"},"institutions":[{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanchen Pang","raw_affiliation_strings":["College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Qingdao Institute of Software, China University of Petroleum (East China),Qingdao,China","institution_ids":["https://openalex.org/I4210162190"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5124196296"],"corresponding_institution_ids":["https://openalex.org/I4210162190"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.64500724,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"6376","last_page":"6383"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11307","display_name":"Domain Adaptation and Few-Shot Learning","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.7089999914169312},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.42559999227523804},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.42399999499320984},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.39559999108314514},{"id":"https://openalex.org/keywords/mechanism","display_name":"Mechanism (biology)","score":0.38940000534057617},{"id":"https://openalex.org/keywords/binomial-distribution","display_name":"Binomial distribution","score":0.3650999963283539},{"id":"https://openalex.org/keywords/feature-learning","display_name":"Feature learning","score":0.3449999988079071},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.3260999917984009}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7318000197410583},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.7089999914169312},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6450999975204468},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.47609999775886536},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.42559999227523804},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.42399999499320984},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.39559999108314514},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.38940000534057617},{"id":"https://openalex.org/C41054675","wikidata":"https://www.wikidata.org/wiki/Q185547","display_name":"Binomial distribution","level":2,"score":0.3650999963283539},{"id":"https://openalex.org/C59404180","wikidata":"https://www.wikidata.org/wiki/Q17013334","display_name":"Feature learning","level":2,"score":0.3449999988079071},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33480000495910645},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.3260999917984009},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.3125},{"id":"https://openalex.org/C199335787","wikidata":"https://www.wikidata.org/wiki/Q743364","display_name":"Negative binomial distribution","level":3,"score":0.30720001459121704},{"id":"https://openalex.org/C2780980858","wikidata":"https://www.wikidata.org/wiki/Q110022","display_name":"Dual (grammatical number)","level":2,"score":0.3037000000476837},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.27390000224113464},{"id":"https://openalex.org/C2776145971","wikidata":"https://www.wikidata.org/wiki/Q30673951","display_name":"Labeled data","level":2,"score":0.273499995470047},{"id":"https://openalex.org/C2984842247","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep neural networks","level":3,"score":0.27320000529289246},{"id":"https://openalex.org/C186767784","wikidata":"https://www.wikidata.org/wiki/Q5162841","display_name":"Consensus clustering","level":5,"score":0.267300009727478},{"id":"https://openalex.org/C105611402","wikidata":"https://www.wikidata.org/wiki/Q2976589","display_name":"Spectral clustering","level":3,"score":0.25850000977516174},{"id":"https://openalex.org/C138958017","wikidata":"https://www.wikidata.org/wiki/Q190087","display_name":"Data type","level":2,"score":0.25850000977516174},{"id":"https://openalex.org/C8038995","wikidata":"https://www.wikidata.org/wiki/Q1152135","display_name":"Unsupervised learning","level":2,"score":0.2556999921798706}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm66473.2025.11356414","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm66473.2025.11356414","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.5637945532798767}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1608459536","https://openalex.org/W2069089843","https://openalex.org/W2069295116","https://openalex.org/W2122111042","https://openalex.org/W2605810679","https://openalex.org/W2743416243","https://openalex.org/W2769933977","https://openalex.org/W2783644856","https://openalex.org/W2901677030","https://openalex.org/W2937917790","https://openalex.org/W2951381561","https://openalex.org/W2964015378","https://openalex.org/W3009302866","https://openalex.org/W3138479716","https://openalex.org/W3163972593","https://openalex.org/W3164156820","https://openalex.org/W3164766680","https://openalex.org/W4205281625","https://openalex.org/W4205916264","https://openalex.org/W4212836561","https://openalex.org/W4293237882","https://openalex.org/W4297243391","https://openalex.org/W4385332084","https://openalex.org/W4405754608","https://openalex.org/W4408537402","https://openalex.org/W4416310693"],"related_works":[],"abstract_inverted_index":{"Single-cell":[0],"RNA":[1],"sequencing":[2],"technology":[3],"holds":[4,101],"significant":[5],"importance":[6],"in":[7,111],"biomedical":[8],"research,":[9],"yet":[10],"its":[11],"inherent":[12],"characteristics\u2014including":[13],"high":[14],"dimensionality,":[15],"technical":[16],"noise,":[17],"and":[18,56,72,81,115],"sparsity\u2014pose":[19],"substantial":[20],"challenges":[21],"for":[22,39,69],"cellular":[23,113],"clustering":[24,37],"analysis.":[25],"To":[26],"address":[27],"these":[28],"limitations,":[29],"this":[30],"paper":[31],"introduces":[32],"scDVCC,":[33],"a":[34],"novel":[35],"deep":[36],"framework":[38],"scRNA-seq":[40],"data":[41,70,109],"based":[42],"on":[43],"dual-view":[44],"contrastive":[45],"learning.":[46],"Our":[47],"approach":[48],"constructs":[49],"dual":[50],"views":[51],"through":[52],"K-nearest":[53],"neighbor":[54],"graphs":[55],"diffusion":[57],"maps,":[58],"employs":[59],"graph":[60],"neural":[61],"networks":[62],"integrated":[63],"with":[64],"zero-inflated":[65],"negative":[66],"binomial":[67],"distribution":[68],"modeling,":[71],"incorporates":[73],"an":[74],"dual-contrastive":[75],"learning":[76],"mechanism":[77],"encompassing":[78],"both":[79],"instance-level":[80],"cluster-level":[82],"discrimination":[83],"enhancement.":[84],"Experimental":[85],"validation":[86],"demonstrates":[87],"that":[88],"scDVCC":[89],"significantly":[90],"outperforms":[91],"seven":[92],"advanced":[93],"methods":[94],"across":[95],"nine":[96],"benchmark":[97],"datasets.":[98],"This":[99],"advancement":[100],"strong":[102],"potential":[103],"to":[104],"facilitate":[105],"applications":[106],"of":[107],"single-cell":[108],"analysis":[110],"deciphering":[112],"heterogeneity":[114],"elucidating":[116],"disease":[117],"mechanisms.":[118]},"counts_by_year":[],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2026-01-30T00:00:00"}