{"id":"https://openalex.org/W7126100364","doi":"https://doi.org/10.1109/bibm66473.2025.11356377","title":"DP-GPT: GPT-Driven Gene Text Feature Embedding Fused with Gene Expression Data for Depression Prediction","display_name":"DP-GPT: GPT-Driven Gene Text Feature Embedding Fused with Gene Expression Data for Depression Prediction","publication_year":2025,"publication_date":"2025-12-15","ids":{"openalex":"https://openalex.org/W7126100364","doi":"https://doi.org/10.1109/bibm66473.2025.11356377"},"language":null,"primary_location":{"id":"doi:10.1109/bibm66473.2025.11356377","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm66473.2025.11356377","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027492750","display_name":"M. Zeng","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Min Zeng","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University,Changsha,China,410083"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University,Changsha,China,410083","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124230797","display_name":"Junyu Gao","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junyu Gao","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University,Changsha,China,410083"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University,Changsha,China,410083","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124252388","display_name":"Qianpei Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianpei Liu","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University,Changsha,China,410083"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University,Changsha,China,410083","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061951336","display_name":"Yiming Li","orcid":"https://orcid.org/0000-0003-2111-3939"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiming Li","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University,Changsha,China,410083"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University,Changsha,China,410083","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124265793","display_name":"Fuhao Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fuhao Zhang","raw_affiliation_strings":["College of Information Engineering, Northwest A&F University,Yangling,Shaanxi,China,712100"],"affiliations":[{"raw_affiliation_string":"College of Information Engineering, Northwest A&F University,Yangling,Shaanxi,China,712100","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044328870","display_name":"Ruiqing Zheng","orcid":"https://orcid.org/0000-0001-6372-6798"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruiqing Zheng","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University,Changsha,China,410083"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University,Changsha,China,410083","institution_ids":["https://openalex.org/I139660479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5124267017","display_name":"Min Li","orcid":null},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Li","raw_affiliation_strings":["School of Computer Science and Engineering, Central South University,Changsha,China,410083"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Engineering, Central South University,Changsha,China,410083","institution_ids":["https://openalex.org/I139660479"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5027492750"],"corresponding_institution_ids":["https://openalex.org/I139660479"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.77110528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12488","display_name":"Mental Health via Writing","score":0.6617000102996826,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12488","display_name":"Mental Health via Writing","score":0.6617000102996826,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.049400001764297485,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.03189999982714653,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.6772000193595886},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.6608999967575073},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5558000206947327},{"id":"https://openalex.org/keywords/classifier","display_name":"Classifier (UML)","score":0.48570001125335693},{"id":"https://openalex.org/keywords/limiting","display_name":"Limiting","score":0.47540000081062317},{"id":"https://openalex.org/keywords/embedding","display_name":"Embedding","score":0.45910000801086426},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.43880000710487366},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"Gene expression profiling","score":0.39469999074935913}],"concepts":[{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6772000193595886},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.6608999967575073},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.557200014591217},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5558000206947327},{"id":"https://openalex.org/C95623464","wikidata":"https://www.wikidata.org/wiki/Q1096149","display_name":"Classifier (UML)","level":2,"score":0.48570001125335693},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.47540000081062317},{"id":"https://openalex.org/C41608201","wikidata":"https://www.wikidata.org/wiki/Q980509","display_name":"Embedding","level":2,"score":0.45910000801086426},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.43880000710487366},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4124000072479248},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4025999903678894},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.40130001306533813},{"id":"https://openalex.org/C18431079","wikidata":"https://www.wikidata.org/wiki/Q1502169","display_name":"Gene expression profiling","level":4,"score":0.39469999074935913},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3862999975681305},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.37130001187324524},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3529999852180481},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.35249999165534973},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.3158000111579895},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.3084999918937683},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3052000105381012},{"id":"https://openalex.org/C2991772755","wikidata":"https://www.wikidata.org/wiki/Q751748","display_name":"Gene interaction","level":3,"score":0.29660001397132874},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2939000129699707},{"id":"https://openalex.org/C105565629","wikidata":"https://www.wikidata.org/wiki/Q1248292","display_name":"Gene prediction","level":4,"score":0.2831999957561493},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.2685000002384186},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.26829999685287476},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.25760000944137573}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm66473.2025.11356377","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm66473.2025.11356377","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"No poverty","score":0.5810394883155823,"id":"https://metadata.un.org/sdg/1"}],"awards":[{"id":"https://openalex.org/G6363746905","display_name":null,"funder_award_id":"62472445","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1968453868","https://openalex.org/W2013469333","https://openalex.org/W2020541351","https://openalex.org/W2064675550","https://openalex.org/W2146512944","https://openalex.org/W2183659962","https://openalex.org/W2194775991","https://openalex.org/W2603756957","https://openalex.org/W2971405760","https://openalex.org/W2980328141","https://openalex.org/W3021228021","https://openalex.org/W3048988555","https://openalex.org/W4401657730","https://openalex.org/W4408762886","https://openalex.org/W4411403346","https://openalex.org/W4411960244","https://openalex.org/W4412712644"],"related_works":[],"abstract_inverted_index":{"In":[0],"recent":[1],"years,":[2],"with":[3,95,107,135],"the":[4,9,120],"improvement":[5],"of":[6,11],"living":[7],"standards,":[8],"prevalence":[10],"depression":[12,41,100,156],"has":[13],"been":[14],"steadily":[15],"increasing,":[16],"making":[17],"it":[18],"a":[19,87,143],"growing":[20],"public":[21],"health":[22],"concern.":[23],"Gene":[24,122],"expression":[25,39,97,105,138],"data":[26,98,106,139],"can":[27,161],"reveal":[28],"links":[29],"between":[30],"genes":[31,70],"and":[32,71,115,140],"diseases.":[33],"Studies":[34],"have":[35],"shown":[36],"that":[37,150],"gene":[38,89,96,104,113,137],"in":[40,155],"patients":[42],"differs":[43],"significantly":[44],"from":[45,68,119,164],"healthy":[46],"individuals,":[47],"offering":[48],"potential":[49],"for":[50,99,145],"early":[51],"detection.":[52],"However,":[53],"existing":[54],"methods":[55],"often":[56],"depend":[57],"on":[58],"selecting":[59],"differentially":[60],"expressed":[61],"genes,":[62],"which":[63],"may":[64],"overlook":[65],"important":[66],"signals":[67],"other":[69],"are":[72,117,133],"vulnerable":[73],"to":[74,128],"batch":[75],"effects,":[76],"limiting":[77],"model":[78],"generalization.":[79],"To":[80],"address":[81],"these":[82],"limitations,":[83],"we":[84],"propose":[85],"DP-GPT,":[86],"GPT-driven":[88],"text":[90],"feature":[91,130],"embedding":[92],"framework":[93],"fused":[94,134],"prediction.":[101,146,157],"DP-GPT":[102,151],"integrates":[103],"features":[108],"extracted":[109],"by":[110],"GPT.":[111],"Specifically,":[112],"names":[114],"summaries":[116],"obtained":[118,163],"NCBI":[121],"database,":[123],"then":[124],"embedded":[125],"using":[126],"GPT":[127],"generate":[129],"vectors.":[131],"These":[132],"sample":[136],"fed":[141],"into":[142],"classifier":[144],"Extensive":[147],"experiments":[148],"show":[149],"achieves":[152],"superior":[153],"performance":[154],"The":[158],"source":[159],"code":[160],"be":[162],"https://github.com/CSUBioGroup/DP-GPT.":[165]},"counts_by_year":[],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2026-01-30T00:00:00"}