{"id":"https://openalex.org/W4406260927","doi":"https://doi.org/10.1109/bibm62325.2024.10822654","title":"Early Prediction of Depressive Episodes in Mood Disorders Using Circadian Rhythm Indicators and Deep Learning","display_name":"Early Prediction of Depressive Episodes in Mood Disorders Using Circadian Rhythm Indicators and Deep Learning","publication_year":2024,"publication_date":"2024-12-03","ids":{"openalex":"https://openalex.org/W4406260927","doi":"https://doi.org/10.1109/bibm62325.2024.10822654"},"language":"en","primary_location":{"id":"doi:10.1109/bibm62325.2024.10822654","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10822654","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078787521","display_name":"Byeongsu Kim","orcid":null},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Byeongsu Kim","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086644266","display_name":"Minsu Chae","orcid":null},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Minsu Chae","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075459146","display_name":"Yi-Hyun Kim","orcid":null},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yihyun Kim","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Seokjin Kong","orcid":null},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seokjin Kong","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106407346","display_name":"Yeongmin Kim","orcid":"https://orcid.org/0009-0006-2330-691X"},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Yeongmin Kim","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Taewon Jung","orcid":null},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Taewon Jung","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065826868","display_name":"Jaegwon Jeong","orcid":"https://orcid.org/0000-0003-1152-833X"},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jaegwon Jeong","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100724796","display_name":"Soohyun Park","orcid":"https://orcid.org/0000-0002-6556-9746"},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Soohyun Park","raw_affiliation_strings":["Korea University,Chronobiology Institute,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,Chronobiology Institute,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029302791","display_name":"Chul\u2010Hyun Cho","orcid":"https://orcid.org/0000-0002-1663-9680"},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chul-Hyun Cho","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004734937","display_name":"Ji Won Yeom","orcid":"https://orcid.org/0000-0003-0038-2101"},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji Won Yeom","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064167751","display_name":"Taek Lee","orcid":"https://orcid.org/0000-0003-2277-8211"},"institutions":[{"id":"https://openalex.org/I51926615","display_name":"Sun Moon University","ror":"https://ror.org/009e5cd49","country_code":"KR","type":"education","lineage":["https://openalex.org/I51926615"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Taek Lee","raw_affiliation_strings":["SunMoon University,Dept. of Computer Science and Engineering,Asan,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SunMoon University,Dept. of Computer Science and Engineering,Asan,Republic of Korea","institution_ids":["https://openalex.org/I51926615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079162930","display_name":"Heon\u2010Jeong Lee","orcid":"https://orcid.org/0000-0002-9560-2383"},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Heon-Jeong Lee","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]},{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051519943","display_name":"HwaMin Lee\ufffd","orcid":"https://orcid.org/0000-0002-6482-3511"},"institutions":[{"id":"https://openalex.org/I197347611","display_name":"Korea University","ror":"https://ror.org/047dqcg40","country_code":"KR","type":"education","lineage":["https://openalex.org/I197347611"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Hwamin Lee","raw_affiliation_strings":["Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Biomedical Informatics,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]},{"raw_affiliation_string":"Korea University,College of Medicine,Dept. of Psychiatry,Seoul,Republic of Korea","institution_ids":["https://openalex.org/I197347611"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"6411","last_page":"6418"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T13283","display_name":"Mental Health Research Topics","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.932200014591217,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"Circadian rhythm","score":0.8217015266418457},{"id":"https://openalex.org/keywords/rhythm","display_name":"Rhythm","score":0.6994996070861816},{"id":"https://openalex.org/keywords/mood","display_name":"Mood","score":0.6681991219520569},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.4163317084312439},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.38079607486724854},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3501700460910797},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3226322829723358},{"id":"https://openalex.org/keywords/clinical-psychology","display_name":"Clinical psychology","score":0.29161226749420166},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.23896342515945435},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.23450422286987305},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.22225981950759888}],"concepts":[{"id":"https://openalex.org/C121446783","wikidata":"https://www.wikidata.org/wiki/Q208353","display_name":"Circadian rhythm","level":2,"score":0.8217015266418457},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.6994996070861816},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.6681991219520569},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4163317084312439},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38079607486724854},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3501700460910797},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3226322829723358},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.29161226749420166},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23896342515945435},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23450422286987305},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.22225981950759888}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm62325.2024.10822654","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10822654","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4399999976158142,"display_name":"Quality Education","id":"https://metadata.un.org/sdg/4"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1981722146","https://openalex.org/W2013987967","https://openalex.org/W2017713202","https://openalex.org/W2048957687","https://openalex.org/W2103987983","https://openalex.org/W2121778399","https://openalex.org/W2128840685","https://openalex.org/W2149964364","https://openalex.org/W2519531315","https://openalex.org/W2557200837","https://openalex.org/W2572952770","https://openalex.org/W2761314164","https://openalex.org/W2787556368","https://openalex.org/W2896565847","https://openalex.org/W2929646074","https://openalex.org/W2980148744","https://openalex.org/W2981182836","https://openalex.org/W2996333298","https://openalex.org/W3084138672","https://openalex.org/W3111758161","https://openalex.org/W3217777237","https://openalex.org/W4210965604","https://openalex.org/W4211013640","https://openalex.org/W4281750093","https://openalex.org/W4296802028","https://openalex.org/W4298112007","https://openalex.org/W4318777968","https://openalex.org/W4327894021","https://openalex.org/W4385497950","https://openalex.org/W4387737913","https://openalex.org/W4390734451","https://openalex.org/W4391885119","https://openalex.org/W4393965243","https://openalex.org/W6631463610","https://openalex.org/W6864654386"],"related_works":["https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W4387369504","https://openalex.org/W3046775127","https://openalex.org/W4394896187","https://openalex.org/W3170094116","https://openalex.org/W4386462264","https://openalex.org/W3107602296","https://openalex.org/W4364306694","https://openalex.org/W4312192474"],"abstract_inverted_index":{"The":[0],"early":[1,162],"prediction":[2],"of":[3,125,157,164,172,188],"depressive":[4,137,150],"mood":[5,82,165],"episodes":[6,83],"is":[7],"crucial":[8],"for":[9,161],"effective":[10],"intervention":[11,182],"in":[12,64,86,176],"patients":[13],"with":[14,38,104,139],"Major":[15],"Depressive":[16],"Disorder":[17,21,60],"(MDD)":[18],"and":[19,36,75,94,113,136],"Bipolar":[20],"(BD).":[22],"This":[23],"study":[24],"explores":[25],"a":[26,39],"predictive":[27],"framework":[28],"leveraging":[29],"digital":[30,159],"phenotypic":[31],"data":[32,53],"collected":[33],"from":[34,54],"smartphones":[35],"smartwatches,":[37],"focus":[40],"on":[41],"circadian":[42,133],"rhythm":[43,134],"indicators":[44],"such":[45],"as":[46],"Dim":[47],"Light":[48],"Melatonin":[49],"Onset":[50],"(DLMO).":[51],"Using":[52],"164":[55],"participants":[56],"within":[57],"the":[58,105,109,114,130,155,170],"Mood":[59],"Cohort":[61],"Research":[62],"Consortium":[63],"Korea,":[65],"time-series":[66],"features":[67],"related":[68],"to":[69,80,100,144,148],"sleep,":[70],"heart":[71],"rate,":[72],"activity":[73],"levels,":[74],"light":[76],"exposure":[77],"were":[78,98],"processed":[79],"predict":[81],"seven":[84],"days":[85],"advance.":[87],"Deep":[88],"learning":[89],"models,":[90],"including":[91],"LSTM,":[92],"GRU,":[93],"an":[95],"LSTM-GRU":[96],"hybrid,":[97],"applied":[99],"analyze":[101],"this":[102],"data,":[103],"GRU":[106],"model":[107,116],"achieving":[108],"highest":[110],"recall":[111],"(0.767)":[112],"LSTM":[115],"displaying":[117],"superior":[118],"robustness":[119],"across":[120],"metrics.":[121],"SHAP":[122],"value":[123],"analysis":[124],"DLMO-related":[126],"variables":[127],"further":[128],"underscored":[129],"association":[131],"between":[132],"disruptions":[135],"episodes,":[138],"delayed":[140],"wake-up":[141],"times":[142],"relative":[143],"ideal":[145],"schedules":[146],"linked":[147],"increased":[149],"symptoms.":[151],"Our":[152],"findings":[153],"demonstrate":[154],"feasibility":[156],"using":[158],"phenotypes":[160],"detection":[163],"episodes.":[166],"These":[167],"results":[168],"highlight":[169],"potential":[171],"automated":[173],"monitoring":[174,187],"systems":[175],"clinical":[177],"practice,":[178],"which":[179],"enable":[180],"proactive":[181],"strategies":[183],"through":[184],"continuous,":[185],"objective":[186],"patient":[189],"conditions.":[190]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}