{"id":"https://openalex.org/W4406261725","doi":"https://doi.org/10.1109/bibm62325.2024.10822350","title":"Automated Detection and Classification of Pediatric Middle Ear Diseases from CT using Entropy Projection and Feature Interaction","display_name":"Automated Detection and Classification of Pediatric Middle Ear Diseases from CT using Entropy Projection and Feature Interaction","publication_year":2024,"publication_date":"2024-12-03","ids":{"openalex":"https://openalex.org/W4406261725","doi":"https://doi.org/10.1109/bibm62325.2024.10822350"},"language":"en","primary_location":{"id":"doi:10.1109/bibm62325.2024.10822350","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10822350","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108776022","display_name":"Wensheng Li","orcid":"https://orcid.org/0009-0006-1496-4013"},"institutions":[{"id":"https://openalex.org/I139759216","display_name":"Beijing University of Posts and Telecommunications","ror":"https://ror.org/04w9fbh59","country_code":"CN","type":"education","lineage":["https://openalex.org/I139759216"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wensheng Li","raw_affiliation_strings":["Beijing University of Posts and Telecommunications,School of Artificial Intelligence,Beijing,China,100876"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing University of Posts and Telecommunications,School of Artificial Intelligence,Beijing,China,100876","institution_ids":["https://openalex.org/I139759216"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100604078","display_name":"Jie Zhang","orcid":"https://orcid.org/0000-0002-0530-3954"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210144404","display_name":"Beijing Children\u2019s Hospital","ror":"https://ror.org/04skmn292","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Zhang","raw_affiliation_strings":["Capital Medical University, National Center for Children’s Health; Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck Surgery,Beijing Children’s Hospital,Department of Otorhinolaryngology Head and Neck Surgery,Beijing,China,100045"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Capital Medical University, National Center for Children’s Health; Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck Surgery,Beijing Children’s Hospital,Department of Otorhinolaryngology Head and Neck Surgery,Beijing,China,100045","institution_ids":["https://openalex.org/I4210144404","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065604748","display_name":"Jianlin Guo","orcid":"https://orcid.org/0000-0002-1710-221X"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210144404","display_name":"Beijing Children\u2019s Hospital","ror":"https://ror.org/04skmn292","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianlin Guo","raw_affiliation_strings":["Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health,MOE Key Laboratory of Major Diseases in Children,Department of Radiology,Beijing,China,100045"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health,MOE Key Laboratory of Major Diseases in Children,Department of Radiology,Beijing,China,100045","institution_ids":["https://openalex.org/I4210144404","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100626420","display_name":"Xiaoxu Wang","orcid":"https://orcid.org/0000-0002-8364-9467"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210144404","display_name":"Beijing Children\u2019s Hospital","ror":"https://ror.org/04skmn292","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoxu Wang","raw_affiliation_strings":["Capital Medical University, National Center for Children’s Health; Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck Surgery,Beijing Children’s Hospital,Department of Otorhinolaryngology Head and Neck Surgery,Beijing,China,100045"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Capital Medical University, National Center for Children’s Health; Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck Surgery,Beijing Children’s Hospital,Department of Otorhinolaryngology Head and Neck Surgery,Beijing,China,100045","institution_ids":["https://openalex.org/I4210144404","https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102000019","display_name":"Guangyuan Xu","orcid":"https://orcid.org/0009-0004-2483-2968"},"institutions":[{"id":"https://openalex.org/I139759216","display_name":"Beijing University of Posts and Telecommunications","ror":"https://ror.org/04w9fbh59","country_code":"CN","type":"education","lineage":["https://openalex.org/I139759216"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guangyuan Xu","raw_affiliation_strings":["Beijing University of Posts and Telecommunications,School of Artificial Intelligence,Beijing,China,100876"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing University of Posts and Telecommunications,School of Artificial Intelligence,Beijing,China,100876","institution_ids":["https://openalex.org/I139759216"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035313775","display_name":"Yun Peng","orcid":"https://orcid.org/0000-0001-8213-9716"},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210144404","display_name":"Beijing Children\u2019s Hospital","ror":"https://ror.org/04skmn292","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210144404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Peng","raw_affiliation_strings":["Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health,MOE Key Laboratory of Major Diseases in Children,Department of Radiology,Beijing,China,100045"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health,MOE Key Laboratory of Major Diseases in Children,Department of Radiology,Beijing,China,100045","institution_ids":["https://openalex.org/I4210144404","https://openalex.org/I183519381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085003843","display_name":"Liyun Tu","orcid":"https://orcid.org/0000-0002-3389-400X"},"institutions":[{"id":"https://openalex.org/I139759216","display_name":"Beijing University of Posts and Telecommunications","ror":"https://ror.org/04w9fbh59","country_code":"CN","type":"education","lineage":["https://openalex.org/I139759216"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liyun Tu","raw_affiliation_strings":["Beijing University of Posts and Telecommunications,School of Artificial Intelligence,Beijing,China,100876"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing University of Posts and Telecommunications,School of Artificial Intelligence,Beijing,China,100876","institution_ids":["https://openalex.org/I139759216"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"2156","last_page":"2163"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14139","display_name":"E-commerce and Technology Innovations","score":0.9745000004768372,"subfield":{"id":"https://openalex.org/subfields/1403","display_name":"Business and International Management"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T14139","display_name":"E-commerce and Technology Innovations","score":0.9745000004768372,"subfield":{"id":"https://openalex.org/subfields/1403","display_name":"Business and International Management"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10861","display_name":"Ear Surgery and Otitis Media","score":0.9388999938964844,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6273991465568542},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5563971996307373},{"id":"https://openalex.org/keywords/entropy","display_name":"Entropy (arrow of time)","score":0.5266225934028625},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5186852216720581},{"id":"https://openalex.org/keywords/projection","display_name":"Projection (relational algebra)","score":0.4753042161464691},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.41822510957717896},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.10131731629371643},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.062267005443573}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6273991465568542},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5563971996307373},{"id":"https://openalex.org/C106301342","wikidata":"https://www.wikidata.org/wiki/Q4117933","display_name":"Entropy (arrow of time)","level":2,"score":0.5266225934028625},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5186852216720581},{"id":"https://openalex.org/C57493831","wikidata":"https://www.wikidata.org/wiki/Q3134666","display_name":"Projection (relational algebra)","level":2,"score":0.4753042161464691},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.41822510957717896},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.10131731629371643},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.062267005443573},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm62325.2024.10822350","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10822350","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1933349210","https://openalex.org/W2106905112","https://openalex.org/W2115414021","https://openalex.org/W2133063949","https://openalex.org/W2150035316","https://openalex.org/W2154577669","https://openalex.org/W2189397296","https://openalex.org/W2194775991","https://openalex.org/W2295739661","https://openalex.org/W2475334473","https://openalex.org/W2509235963","https://openalex.org/W2537419390","https://openalex.org/W2604662567","https://openalex.org/W2731736087","https://openalex.org/W2791680898","https://openalex.org/W2793954249","https://openalex.org/W2898085636","https://openalex.org/W2905189062","https://openalex.org/W2961308354","https://openalex.org/W2962858109","https://openalex.org/W2963150162","https://openalex.org/W2964182926","https://openalex.org/W2973987296","https://openalex.org/W2980254909","https://openalex.org/W2999443745","https://openalex.org/W3006011959","https://openalex.org/W3014041368","https://openalex.org/W3035406940","https://openalex.org/W3118439879","https://openalex.org/W3138516171","https://openalex.org/W3148821605","https://openalex.org/W4206784078","https://openalex.org/W4212764404","https://openalex.org/W4246193833","https://openalex.org/W4281288638","https://openalex.org/W4288391270","https://openalex.org/W4315630813","https://openalex.org/W4319300975","https://openalex.org/W4387789677","https://openalex.org/W4390889814","https://openalex.org/W6637373629","https://openalex.org/W6767612737","https://openalex.org/W6784333009","https://openalex.org/W6794262402","https://openalex.org/W6857129140"],"related_works":["https://openalex.org/W3147584709","https://openalex.org/W2977677679","https://openalex.org/W1992327129","https://openalex.org/W2351452215","https://openalex.org/W2381986121","https://openalex.org/W2617963432","https://openalex.org/W2370918718","https://openalex.org/W2256933480","https://openalex.org/W2033914206","https://openalex.org/W2042327336"],"abstract_inverted_index":{"Existing":[0],"methods":[1,35,66],"for":[2,91,134,161],"diagnosing":[3],"middle":[4,129],"ear":[5],"diseases":[6],"using":[7,104],"temporal":[8,105],"bone":[9,106],"computed":[10],"tomography":[11],"(CT)":[12],"imaging":[13],"primarily":[14],"focus":[15],"on":[16,37,70,170],"adult":[17],"datasets":[18],"and":[19,28,40,43,101,153,157,190,208],"require":[20],"labor-intensive":[21],"manual":[22],"input":[23],"from":[24,176],"radiologists":[25],"to":[26,212],"label":[27],"select":[29],"regions":[30],"of":[31,52,61,94,127,173,188,193],"interest":[32],"(ROIs).":[33],"These":[34],"rely":[36],"prior":[38,137],"knowledge":[39],"introduce":[41,141],"inter-":[42],"intra-observer":[44],"variability.":[45,80],"Additionally,":[46],"the":[47,58,113,123,128,132,210],"selected":[48],"ROIs":[49,117],"typically":[50],"consist":[51],"a":[53,87,142,148,155,171,185],"few":[54],"2D":[55],"slices,":[56],"underutilizing":[57],"3D":[59,116,124],"capabilities":[60],"CT":[62,107,174],"imaging.":[63,108],"Moreover,":[64],"these":[65,83],"are":[67],"not":[68],"reproducible":[69],"pediatric":[71,95,178],"datasets,":[72],"where":[73],"rapidly":[74],"developing":[75],"heads":[76],"exhibit":[77],"greater":[78],"morphological":[79],"To":[81],"address":[82],"challenges,":[84],"we":[85],"developed":[86],"fully":[88],"automated":[89,205],"framework":[90],"precise":[92],"diagnosis":[93],"chronic":[96],"suppurative":[97],"otitis":[98],"media":[99],"(CSOM)":[100],"cholesteatoma":[102],"(MEC)":[103],"Our":[109],"method":[110,183],"automatically":[111],"detects":[112],"most":[114],"informative":[115],"by":[118],"calculating":[119],"entropy":[120],"changes":[121],"in":[122,216],"anatomical":[125],"structures":[126],"ear,":[130],"eliminating":[131],"need":[133],"annotations":[135],"or":[136],"knowledge.":[138],"We":[139],"also":[140],"multi-scale":[143],"classification":[144,186],"network":[145],"that":[146,181],"incorporates":[147],"global-local":[149],"feature":[150,162,166],"interaction":[151],"strategy":[152],"uses":[154],"wide":[156],"deep":[158],"multi-layer":[159],"transformer":[160],"extraction,":[163],"effectively":[164],"learning":[165],"dependencies.":[167],"Experimental":[168],"results":[169],"dataset":[172],"images":[175],"603":[177],"patients":[179],"show":[180],"our":[182],"achieves":[184],"accuracy":[187],"93.17%":[189],"an":[191],"AUC-ROC":[192],"96.84%,":[194],"outperforming":[195],"state-of-the-art":[196],"methods.":[197],"This":[198],"innovative":[199],"approach":[200],"reduces":[201],"radiologists\u2019":[202],"workload,":[203],"aids":[204],"surgical":[206],"navigation,":[207],"has":[209],"potential":[211],"transform":[213],"diagnostic":[214],"workflows":[215],"otolaryngology.":[217]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}