{"id":"https://openalex.org/W4406260775","doi":"https://doi.org/10.1109/bibm62325.2024.10822007","title":"MSSOrg: a multi-scale SSM-based model for organoid location and classification","display_name":"MSSOrg: a multi-scale SSM-based model for organoid location and classification","publication_year":2024,"publication_date":"2024-12-03","ids":{"openalex":"https://openalex.org/W4406260775","doi":"https://doi.org/10.1109/bibm62325.2024.10822007"},"language":"en","primary_location":{"id":"doi:10.1109/bibm62325.2024.10822007","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10822007","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100609338","display_name":"Xun Deng","orcid":"https://orcid.org/0009-0009-6552-8942"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xun Deng","raw_affiliation_strings":["Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351558","display_name":"Zhibin Li","orcid":"https://orcid.org/0000-0002-0501-2305"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhibin Li","raw_affiliation_strings":["Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101138967","display_name":"Gao Mei","orcid":null},"institutions":[{"id":"https://openalex.org/I158842170","display_name":"Chongqing University","ror":"https://ror.org/023rhb549","country_code":"CN","type":"education","lineage":["https://openalex.org/I158842170"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mei Gao","raw_affiliation_strings":["Chongqing University,Chongqing General Hospital,401147"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chongqing University,Chongqing General Hospital,401147","institution_ids":["https://openalex.org/I158842170"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083104543","display_name":"Shaolin Liang","orcid":"https://orcid.org/0000-0003-3122-1343"},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I180662265","display_name":"China Mobile (China)","ror":"https://ror.org/05gftfe97","country_code":"CN","type":"company","lineage":["https://openalex.org/I180662265"]},{"id":"https://openalex.org/I4210159865","display_name":"Xiangya Hospital Central South University","ror":"https://ror.org/05c1yfj14","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159865"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaolin Liang","raw_affiliation_strings":["Xiangya Hospital, Central South University,Ministry of Education-China Mobile Joint Laboratory,Changsha,China,410008"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xiangya Hospital, Central South University,Ministry of Education-China Mobile Joint Laboratory,Changsha,China,410008","institution_ids":["https://openalex.org/I4210159865","https://openalex.org/I180662265","https://openalex.org/I139660479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041041712","display_name":"Tianyu Sun","orcid":"https://orcid.org/0000-0001-9526-4591"},"institutions":[{"id":"https://openalex.org/I87780372","display_name":"Chongqing Medical University","ror":"https://ror.org/017z00e58","country_code":"CN","type":"education","lineage":["https://openalex.org/I87780372"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianyu Sun","raw_affiliation_strings":["University-Town Hospital of Chongqing Medical University,Department of Thoracic Surgery"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University-Town Hospital of Chongqing Medical University,Department of Thoracic Surgery","institution_ids":["https://openalex.org/I87780372"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhipeng Shang","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhipeng Shang","raw_affiliation_strings":["Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054557244","display_name":"Yuhang Yang","orcid":"https://orcid.org/0000-0003-3964-5052"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuhang Yang","raw_affiliation_strings":["Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091505766","display_name":"Yuan Wei","orcid":"https://orcid.org/0000-0002-3891-4006"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yafang Wei","raw_affiliation_strings":["Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008221100","display_name":"Lun Hu","orcid":"https://orcid.org/0000-0002-1591-8549"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lun Hu","raw_affiliation_strings":["Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078808331","display_name":"Pengwei Hu","orcid":"https://orcid.org/0000-0001-5974-7932"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106108","display_name":"Xinjiang Technical Institute of Physics & Chemistry","ror":"https://ror.org/00x44h034","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106108"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengwei Hu","raw_affiliation_strings":["Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Academy of Sciences,The Xinjiang Technical Institute of Physics and Chemistry,Urumqi,China,830011","institution_ids":["https://openalex.org/I4210106108","https://openalex.org/I19820366"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9118,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.79302087,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"3156","last_page":"3159"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.10249999910593033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.10249999910593033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/organoid","display_name":"Organoid","score":0.8690192699432373},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6869033575057983},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.6242313385009766},{"id":"https://openalex.org/keywords/cartography","display_name":"Cartography","score":0.11067679524421692},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.07160165905952454},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.06457865238189697},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.06403011083602905}],"concepts":[{"id":"https://openalex.org/C31695470","wikidata":"https://www.wikidata.org/wiki/Q11293125","display_name":"Organoid","level":2,"score":0.8690192699432373},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6869033575057983},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.6242313385009766},{"id":"https://openalex.org/C58640448","wikidata":"https://www.wikidata.org/wiki/Q42515","display_name":"Cartography","level":1,"score":0.11067679524421692},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.07160165905952454},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.06457865238189697},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06403011083602905}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm62325.2024.10822007","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10822007","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6200000047683716,"id":"https://metadata.un.org/sdg/13","display_name":"Climate action"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1536680647","https://openalex.org/W2520107693","https://openalex.org/W2524820142","https://openalex.org/W2795334574","https://openalex.org/W2903061871","https://openalex.org/W2941549157","https://openalex.org/W2943456337","https://openalex.org/W3033755050","https://openalex.org/W3128193046","https://openalex.org/W3184439416","https://openalex.org/W3195037280","https://openalex.org/W3210520893","https://openalex.org/W4210761061","https://openalex.org/W4225127490","https://openalex.org/W4246399668","https://openalex.org/W4313452330","https://openalex.org/W4321374203","https://openalex.org/W4375928910","https://openalex.org/W4386076325","https://openalex.org/W4389317742","https://openalex.org/W4389326242","https://openalex.org/W4390970059","https://openalex.org/W4391047432","https://openalex.org/W4398810114","https://openalex.org/W4402754006","https://openalex.org/W4403770406","https://openalex.org/W6798838024","https://openalex.org/W6809665764","https://openalex.org/W6859298233","https://openalex.org/W6861342692","https://openalex.org/W6868582632"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W4386439204","https://openalex.org/W4401794395","https://openalex.org/W3133804457","https://openalex.org/W3033121461","https://openalex.org/W3094248195","https://openalex.org/W2811397904","https://openalex.org/W3047600752"],"abstract_inverted_index":{"Organoids,":[0],"3D":[1],"in":[2,63,111,117,144],"vitro":[3],"cultures":[4],"replicating":[5],"their":[6],"tissue":[7],"or":[8],"organ":[9],"of":[10,58],"origin,":[11],"hold":[12],"great":[13],"potential":[14],"for":[15,84,135],"disease":[16,139],"research,":[17,140],"drug":[18,136],"testing,":[19],"and":[20,36,41,46,65,67,87,91,101,108,121,138],"regenerative":[21],"medicine.":[22],"However,":[23],"current":[24],"analysis":[25,35],"methods":[26,43],"primarily":[27],"rely":[28,48],"on":[29,49],"staining":[30],"techniques,":[31],"which":[32,60],"limit":[33],"high-throughput":[34],"require":[37],"manual":[38],"adjustments.":[39],"Automated":[40],"non-invasive":[42],"remain":[44],"underexplored,":[45],"most":[47],"small-scale":[50],"datasets":[51],"that":[52],"fail":[53],"to":[54,97],"capture":[55],"the":[56],"complexity":[57],"organoids,":[59],"vary":[61],"significantly":[62],"shape":[64],"size":[66],"have":[68],"more":[69],"intricate":[70],"backgrounds":[71],"than":[72],"cells.":[73],"To":[74],"address":[75],"these":[76,145],"limitations,":[77],"we":[78],"developed":[79],"MSSOrg,":[80],"a":[81,132],"multiscale":[82],"framework":[83],"organoid":[85,119,129],"localization":[86],"classification,":[88],"integrating":[89],"Local":[90],"Global":[92],"State":[93],"Space":[94],"Models":[95],"(SSMs)":[96],"balance":[98],"pixel":[99],"dependencies":[100],"texture":[102],"features.":[103],"MSSOrg":[104],"mitigates":[105],"background":[106],"interference":[107],"image":[109],"noise":[110],"bright-field":[112],"images,":[113],"achieving":[114],"superior":[115],"performance":[116],"both":[118],"detection":[120],"morphological":[122],"classification.":[123],"This":[124],"innovation":[125],"enables":[126],"real-time,":[127],"large-scale":[128],"analysis,":[130],"providing":[131],"powerful":[133],"tool":[134],"screening":[137],"ultimately":[141],"accelerating":[142],"progress":[143],"fields.":[146]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}