{"id":"https://openalex.org/W4406271257","doi":"https://doi.org/10.1109/bibm62325.2024.10821906","title":"An Improved Prediction Model for Phage-host Interactions Based on Fusing Global and Local Semantics of RBP Information","display_name":"An Improved Prediction Model for Phage-host Interactions Based on Fusing Global and Local Semantics of RBP Information","publication_year":2024,"publication_date":"2024-12-03","ids":{"openalex":"https://openalex.org/W4406271257","doi":"https://doi.org/10.1109/bibm62325.2024.10821906"},"language":"en","primary_location":{"id":"doi:10.1109/bibm62325.2024.10821906","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10821906","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086544667","display_name":"Yifei Chen","orcid":"https://orcid.org/0009-0009-2002-7909"},"institutions":[{"id":"https://openalex.org/I40963666","display_name":"Central China Normal University","ror":"https://ror.org/03x1jna21","country_code":"CN","type":"education","lineage":["https://openalex.org/I40963666"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yifei Chen","raw_affiliation_strings":["Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079"],"affiliations":[{"raw_affiliation_string":"Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079","institution_ids":["https://openalex.org/I40963666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100299036","display_name":"Wei\u2010Zhong Zhao","orcid":"https://orcid.org/0000-0002-1224-8455"},"institutions":[{"id":"https://openalex.org/I40963666","display_name":"Central China Normal University","ror":"https://ror.org/03x1jna21","country_code":"CN","type":"education","lineage":["https://openalex.org/I40963666"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weizhong Zhao","raw_affiliation_strings":["Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079"],"affiliations":[{"raw_affiliation_string":"Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079","institution_ids":["https://openalex.org/I40963666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103248641","display_name":"Xinhui Tu","orcid":"https://orcid.org/0009-0000-6570-009X"},"institutions":[{"id":"https://openalex.org/I40963666","display_name":"Central China Normal University","ror":"https://ror.org/03x1jna21","country_code":"CN","type":"education","lineage":["https://openalex.org/I40963666"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhui Tu","raw_affiliation_strings":["Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079"],"affiliations":[{"raw_affiliation_string":"Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079","institution_ids":["https://openalex.org/I40963666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039602194","display_name":"Tingting He","orcid":"https://orcid.org/0000-0002-5677-2718"},"institutions":[{"id":"https://openalex.org/I40963666","display_name":"Central China Normal University","ror":"https://ror.org/03x1jna21","country_code":"CN","type":"education","lineage":["https://openalex.org/I40963666"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tingting He","raw_affiliation_strings":["Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079"],"affiliations":[{"raw_affiliation_string":"Central China Normal University,Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning,Wuhan,PR China,430079","institution_ids":["https://openalex.org/I40963666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5086544667"],"corresponding_institution_ids":["https://openalex.org/I40963666"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.23259917,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1449","last_page":"1452"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9767000079154968,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9767000079154968,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/semantics","display_name":"Semantics (computer science)","score":0.6609019637107849},{"id":"https://openalex.org/keywords/host","display_name":"Host (biology)","score":0.626664936542511},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6167095303535461},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4229547381401062},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.2448696494102478},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17388781905174255},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.09670528769493103}],"concepts":[{"id":"https://openalex.org/C184337299","wikidata":"https://www.wikidata.org/wiki/Q1437428","display_name":"Semantics (computer science)","level":2,"score":0.6609019637107849},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.626664936542511},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6167095303535461},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4229547381401062},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.2448696494102478},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17388781905174255},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09670528769493103}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm62325.2024.10821906","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm62325.2024.10821906","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311687","display_name":"Ministry of Education","ror":"https://ror.org/03m01yf64"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322186","display_name":"Natural Science Foundation of Hubei Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W2245444176","https://openalex.org/W2345960958","https://openalex.org/W2559100382","https://openalex.org/W2734399491","https://openalex.org/W2917508998","https://openalex.org/W3045258582","https://openalex.org/W3048846953","https://openalex.org/W3051688178","https://openalex.org/W3118981004","https://openalex.org/W3177500196","https://openalex.org/W3196522895","https://openalex.org/W4319317988","https://openalex.org/W4378952262","https://openalex.org/W4381050540","https://openalex.org/W4385212722","https://openalex.org/W4387849039","https://openalex.org/W4390991954","https://openalex.org/W4401507037","https://openalex.org/W4402040945"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Accurate":[0],"prediction":[1,62,72],"of":[2,24,28,45,148,165],"phage-host":[3,37,153],"interactions":[4],"(PHIs)":[5],"is":[6,79,127,141],"crucial":[7],"for":[8,21,89],"phage":[9,91,132],"therapy":[10],"and":[11,57,85,102,134,159],"antimicrobial":[12],"substitution":[13],"research.":[14],"Although":[15],"many":[16],"methods":[17],"have":[18],"been":[19],"proposed":[20,167],"the":[22,33,41,52,76,96,113,120,124,131,145,151,160,163,166],"task":[23],"PHIs":[25,71],"prediction,":[26],"most":[27],"them":[29],"fail":[30],"to":[31,60,118,143],"employ":[32],"biological":[34],"knowledge":[35],"in":[36,51,74,106],"interaction,":[38],"such":[39],"as":[40],"receptor-binding":[42],"protein":[43,87,114],"(RBP)":[44],"phages":[46,56,107],"plays":[47],"an":[48],"essential":[49],"role":[50],"binding":[53],"mechanism":[54],"between":[55,150],"hosts,":[58,112],"leading":[59],"undesirable":[61],"performance.":[63],"In":[64],"this":[65],"study,":[66],"we":[67],"propose":[68],"a":[69,139],"novel":[70],"model":[73],"which":[75,100,138],"RBP":[77,83],"data":[78],"explicitly":[80],"employed.":[81],"Specifically,":[82],"information":[84,92],"whole":[86],"sequence":[88],"each":[90],"are":[93,108,116,157],"integrated":[94],"by":[95,99,129],"cross-attention":[97],"mechanism,":[98],"global":[101],"local":[103],"semantics":[104],"contained":[105],"effectively":[109],"captured.":[110],"For":[111],"sequences":[115],"used":[117],"extract":[119],"features":[121,133],"accordingly.":[122],"Then,":[123],"final":[125],"representation":[126],"obtained":[128],"combining":[130],"host":[135],"features,":[136],"on":[137],"MLP":[140],"utilized":[142],"derive":[144],"predicted":[146],"probability":[147],"interaction":[149],"input":[152],"pair.":[154],"Comprehensive":[155],"experiments":[156],"conducted":[158],"results":[161],"demonstrate":[162],"effectiveness":[164],"method.":[168]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
