{"id":"https://openalex.org/W4395471915","doi":"https://doi.org/10.1109/bibm58861.2023.10506212","title":"A Novel Effectiveness Assessment Framework for Neoadjuvant Chemoradiotherapy of Locally Advanced Rectal Cancer Based on Multi-modal Intelligence","display_name":"A Novel Effectiveness Assessment Framework for Neoadjuvant Chemoradiotherapy of Locally Advanced Rectal Cancer Based on Multi-modal Intelligence","publication_year":2023,"publication_date":"2023-12-05","ids":{"openalex":"https://openalex.org/W4395471915","doi":"https://doi.org/10.1109/bibm58861.2023.10506212"},"language":"en","primary_location":{"id":"doi:10.1109/bibm58861.2023.10506212","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/bibm58861.2023.10506212","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112124443","display_name":"Xiao Tian","orcid":null},"institutions":[{"id":"https://openalex.org/I4210096250","display_name":"Beijing Institute of Big Data Research","ror":"https://ror.org/00s1sz824","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I37796252","https://openalex.org/I4210096250"]},{"id":"https://openalex.org/I62853816","display_name":"Beijing University of Civil Engineering and Architecture","ror":"https://ror.org/02yj0p855","country_code":"CN","type":"education","lineage":["https://openalex.org/I62853816"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiao Tian","raw_affiliation_strings":["Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China","Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","institution_ids":["https://openalex.org/I4210096250"]},{"raw_affiliation_string":"School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China","institution_ids":["https://openalex.org/I62853816"]},{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China","institution_ids":["https://openalex.org/I4210096250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082003980","display_name":"Dong Sui","orcid":"https://orcid.org/0000-0002-7887-2111"},"institutions":[{"id":"https://openalex.org/I4210096250","display_name":"Beijing Institute of Big Data Research","ror":"https://ror.org/00s1sz824","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I37796252","https://openalex.org/I4210096250"]},{"id":"https://openalex.org/I62853816","display_name":"Beijing University of Civil Engineering and Architecture","ror":"https://ror.org/02yj0p855","country_code":"CN","type":"education","lineage":["https://openalex.org/I62853816"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dong Sui","raw_affiliation_strings":["Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China","School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","institution_ids":["https://openalex.org/I4210096250"]},{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China","institution_ids":["https://openalex.org/I4210096250"]},{"raw_affiliation_string":"School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China","institution_ids":["https://openalex.org/I62853816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100444161","display_name":"Weifeng Liu","orcid":"https://orcid.org/0000-0002-7798-797X"},"institutions":[{"id":"https://openalex.org/I62853816","display_name":"Beijing University of Civil Engineering and Architecture","ror":"https://ror.org/02yj0p855","country_code":"CN","type":"education","lineage":["https://openalex.org/I62853816"]},{"id":"https://openalex.org/I4210096250","display_name":"Beijing Institute of Big Data Research","ror":"https://ror.org/00s1sz824","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I37796252","https://openalex.org/I4210096250"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weifeng Liu","raw_affiliation_strings":["Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China","Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","institution_ids":["https://openalex.org/I4210096250"]},{"raw_affiliation_string":"School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China","institution_ids":["https://openalex.org/I62853816"]},{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China","institution_ids":["https://openalex.org/I4210096250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103208844","display_name":"Maozu Guo","orcid":"https://orcid.org/0000-0002-3899-1482"},"institutions":[{"id":"https://openalex.org/I4210096250","display_name":"Beijing Institute of Big Data Research","ror":"https://ror.org/00s1sz824","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I37796252","https://openalex.org/I4210096250"]},{"id":"https://openalex.org/I62853816","display_name":"Beijing University of Civil Engineering and Architecture","ror":"https://ror.org/02yj0p855","country_code":"CN","type":"education","lineage":["https://openalex.org/I62853816"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Maozu Guo","raw_affiliation_strings":["Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China","School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China"],"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data,Beijing,China","institution_ids":["https://openalex.org/I4210096250"]},{"raw_affiliation_string":"Beijing Key Laboratory for Intelligent Processing Methods of Architectural Big Data, Beijing, China","institution_ids":["https://openalex.org/I4210096250"]},{"raw_affiliation_string":"School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture, Beijing, China","institution_ids":["https://openalex.org/I62853816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091843570","display_name":"Gongning Luo","orcid":"https://orcid.org/0000-0003-3662-0335"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gongning Luo","raw_affiliation_strings":["Harbin Institute of Technology,Perceptual Computing Research Center,Harbin,China","Perceptual Computing Research Center, Harbin Institute of Technology, Harbin, China"],"affiliations":[{"raw_affiliation_string":"Harbin Institute of Technology,Perceptual Computing Research Center,Harbin,China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Perceptual Computing Research Center, Harbin Institute of Technology, Harbin, China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049558861","display_name":"Kuanquan Wang","orcid":"https://orcid.org/0000-0003-1347-3491"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kuanquan Wang","raw_affiliation_strings":["Harbin Institute of Technology,Perceptual Computing Research Center,Harbin,China","Perceptual Computing Research Center, Harbin Institute of Technology, Harbin, China"],"affiliations":[{"raw_affiliation_string":"Harbin Institute of Technology,Perceptual Computing Research Center,Harbin,China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Perceptual Computing Research Center, Harbin Institute of Technology, Harbin, China","institution_ids":["https://openalex.org/I204983213"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5112124443"],"corresponding_institution_ids":["https://openalex.org/I4210096250","https://openalex.org/I62853816"],"apc_list":null,"apc_paid":null,"fwci":0.2366,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.63175348,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13110","display_name":"Colorectal and Anal Carcinomas","score":0.9592999815940857,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/modal","display_name":"Modal","score":0.6714926362037659},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"Colorectal cancer","score":0.6088382601737976},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4836631715297699},{"id":"https://openalex.org/keywords/neoadjuvant-therapy","display_name":"Neoadjuvant therapy","score":0.4775084853172302},{"id":"https://openalex.org/keywords/chemoradiotherapy","display_name":"Chemoradiotherapy","score":0.4494469165802002},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3789752125740051},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.33570319414138794},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.3274315595626831},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.17907625436782837}],"concepts":[{"id":"https://openalex.org/C71139939","wikidata":"https://www.wikidata.org/wiki/Q910194","display_name":"Modal","level":2,"score":0.6714926362037659},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6088382601737976},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4836631715297699},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.4775084853172302},{"id":"https://openalex.org/C2778424827","wikidata":"https://www.wikidata.org/wiki/Q5090613","display_name":"Chemoradiotherapy","level":3,"score":0.4494469165802002},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3789752125740051},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.33570319414138794},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3274315595626831},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17907625436782837},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm58861.2023.10506212","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/bibm58861.2023.10506212","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G6884966269","display_name":null,"funder_award_id":"61702026,62031003","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W2899190218","https://openalex.org/W2995410603","https://openalex.org/W2995942064","https://openalex.org/W3087124270","https://openalex.org/W3091459859","https://openalex.org/W3092536668","https://openalex.org/W3110963740","https://openalex.org/W3154482193","https://openalex.org/W3170147864","https://openalex.org/W3173451714","https://openalex.org/W3178141259","https://openalex.org/W3194668998","https://openalex.org/W4205398633","https://openalex.org/W4210426142","https://openalex.org/W4214561975","https://openalex.org/W4226269919","https://openalex.org/W4284968770","https://openalex.org/W4286914341","https://openalex.org/W4310117627","https://openalex.org/W4310551570","https://openalex.org/W4313531415","https://openalex.org/W4313897878","https://openalex.org/W4321368951","https://openalex.org/W4322724478","https://openalex.org/W4323308866","https://openalex.org/W6755764656","https://openalex.org/W6801655670"],"related_works":["https://openalex.org/W2374019147","https://openalex.org/W2370262613","https://openalex.org/W4362606997","https://openalex.org/W4361825250","https://openalex.org/W4377092742","https://openalex.org/W2015369371","https://openalex.org/W2142490887","https://openalex.org/W2058137177","https://openalex.org/W2074657476","https://openalex.org/W2460051703"],"abstract_inverted_index":{"Neoadjuvant":[0],"chemoradiotherapy":[1],"(nCRT)":[2],"is":[3],"the":[4,14,35,46,53,56,88,97,100,109,112,135,142,150,156],"stan-dard":[5],"treatment":[6,32],"for":[7,93],"locally":[8],"advanced":[9],"rectal":[10],"cancer":[11,31],"(LARC).":[12],"With":[13],"development":[15],"of":[16,22,55,91,99,111,120,161],"artificial":[17],"intelligence,":[18],"an":[19],"increasing":[20],"number":[21],"studies":[23],"have":[24],"begun":[25],"to":[26,45,86,134,149],"explore":[27],"its":[28,104],"application":[29],"in":[30],"prediction.":[33],"However,":[34],"prior":[36],"methods":[37],"exhibit":[38],"considerable":[39],"variability":[40],"even":[41],"with":[42],"slight":[43],"modifications":[44],"input":[47],"data,":[48],"which":[49],"could":[50],"potentially":[51],"undermine":[52],"reliability":[54],"results.":[57],"In":[58],"this":[59],"paper,":[60],"we":[61],"proposed":[62,113],"RP-Net,":[63],"a":[64,84],"novel":[65],"multi-modal":[66,145,154],"fusion-based":[67],"framework":[68,114],"that":[69,115,126],"combines":[70],"feature":[71],"information":[72],"from":[73],"magnetic":[74],"resonance":[75],"imaging":[76],"(MRI)":[77],"and":[78,103,107,140],"whole":[79],"slide":[80],"images":[81],"(WSI),":[82],"establishing":[83],"relationship":[85,98],"map":[87],"therapeutic":[89],"effectiveness":[90],"nCRT":[92],"LARC.":[94],"We":[95],"investigated":[96],"tumour":[101],"region":[102],"periphery":[105],"tissues,":[106],"demonstrated":[108],"validity":[110],"involving":[116],"11":[117],"different":[118],"combinations":[119,139],"modalities.":[121],"The":[122],"experimental":[123],"results":[124],"revealed":[125],"it":[127],"has":[128],"achieved":[129],"higher":[130],"prediction":[131],"accuracy":[132,160],"compared":[133,148],"four":[136,152],"intra-categories":[137,144],"single-modal":[138],"outperformed":[141],"two":[143],"combinations.":[146],"When":[147],"other":[151],"inter-categories":[153],"combinations,":[155],"fusion":[157],"features":[158],"get":[159],"2":[162],"%":[163],"~":[164],"6%":[165],"improvement":[166],"respectively.":[167]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2025-12-26T23:08:49.675405","created_date":"2025-10-10T00:00:00"}
