{"id":"https://openalex.org/W4390971145","doi":"https://doi.org/10.1109/bibm58861.2023.10385822","title":"Histopathological Cancer Detection with Topological Signatures","display_name":"Histopathological Cancer Detection with Topological Signatures","publication_year":2023,"publication_date":"2023-12-05","ids":{"openalex":"https://openalex.org/W4390971145","doi":"https://doi.org/10.1109/bibm58861.2023.10385822"},"language":"en","primary_location":{"id":"doi:10.1109/bibm58861.2023.10385822","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm58861.2023.10385822","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102819816","display_name":"Ankur Yadav","orcid":"https://orcid.org/0009-0007-7015-0134"},"institutions":[{"id":"https://openalex.org/I87573096","display_name":"University of North Texas at Dallas","ror":"https://ror.org/01n51v443","country_code":"US","type":"education","lineage":["https://openalex.org/I87573096"]},{"id":"https://openalex.org/I162577319","display_name":"The University of Texas at Dallas","ror":"https://ror.org/049emcs32","country_code":"US","type":"education","lineage":["https://openalex.org/I162577319"]},{"id":"https://openalex.org/I3169584401","display_name":"Ursuline Academy of Dallas","ror":"https://ror.org/04jzqkn30","country_code":"US","type":"education","lineage":["https://openalex.org/I3169584401"]},{"id":"https://openalex.org/I4210094379","display_name":"University of Texas Health Science Center at Dallas","ror":"https://ror.org/00q16t150","country_code":"US","type":"education","lineage":["https://openalex.org/I4210094379"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ankur Yadav","raw_affiliation_strings":["U. Texas at Dallas,Dept. of Computer Science","Dept. of Computer Science, U. Texas at Dallas"],"affiliations":[{"raw_affiliation_string":"U. Texas at Dallas,Dept. of Computer Science","institution_ids":["https://openalex.org/I162577319","https://openalex.org/I87573096","https://openalex.org/I4210094379","https://openalex.org/I3169584401"]},{"raw_affiliation_string":"Dept. of Computer Science, U. Texas at Dallas","institution_ids":["https://openalex.org/I162577319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101957611","display_name":"Faisal Ahmed","orcid":"https://orcid.org/0009-0006-5784-5911"},"institutions":[{"id":"https://openalex.org/I162577319","display_name":"The University of Texas at Dallas","ror":"https://ror.org/049emcs32","country_code":"US","type":"education","lineage":["https://openalex.org/I162577319"]},{"id":"https://openalex.org/I87573096","display_name":"University of North Texas at Dallas","ror":"https://ror.org/01n51v443","country_code":"US","type":"education","lineage":["https://openalex.org/I87573096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Faisal Ahmed","raw_affiliation_strings":["U. Texas at Dallas,Dept. of Math. Sciences","Dept. of Math. Sciences, U. Texas at Dallas"],"affiliations":[{"raw_affiliation_string":"U. Texas at Dallas,Dept. of Math. Sciences","institution_ids":["https://openalex.org/I162577319","https://openalex.org/I87573096"]},{"raw_affiliation_string":"Dept. of Math. Sciences, U. Texas at Dallas","institution_ids":["https://openalex.org/I162577319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078438902","display_name":"Ovidiu Daescu","orcid":"https://orcid.org/0000-0002-0278-4174"},"institutions":[{"id":"https://openalex.org/I4210094379","display_name":"University of Texas Health Science Center at Dallas","ror":"https://ror.org/00q16t150","country_code":"US","type":"education","lineage":["https://openalex.org/I4210094379"]},{"id":"https://openalex.org/I87573096","display_name":"University of North Texas at Dallas","ror":"https://ror.org/01n51v443","country_code":"US","type":"education","lineage":["https://openalex.org/I87573096"]},{"id":"https://openalex.org/I3169584401","display_name":"Ursuline Academy of Dallas","ror":"https://ror.org/04jzqkn30","country_code":"US","type":"education","lineage":["https://openalex.org/I3169584401"]},{"id":"https://openalex.org/I162577319","display_name":"The University of Texas at Dallas","ror":"https://ror.org/049emcs32","country_code":"US","type":"education","lineage":["https://openalex.org/I162577319"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ovidiu Daescu","raw_affiliation_strings":["U. Texas at Dallas,Dept. of Computer Science","Dept. of Computer Science, U. Texas at Dallas"],"affiliations":[{"raw_affiliation_string":"U. Texas at Dallas,Dept. of Computer Science","institution_ids":["https://openalex.org/I162577319","https://openalex.org/I87573096","https://openalex.org/I4210094379","https://openalex.org/I3169584401"]},{"raw_affiliation_string":"Dept. of Computer Science, U. Texas at Dallas","institution_ids":["https://openalex.org/I162577319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093735876","display_name":"Reyhan Gedik","orcid":null},"institutions":[{"id":"https://openalex.org/I4210156643","display_name":"Harvard Global Health Institute","ror":"https://ror.org/055avk103","country_code":"US","type":"education","lineage":["https://openalex.org/I4210156643"]},{"id":"https://openalex.org/I4210134579","display_name":"Dana-Farber/Harvard Cancer Center","ror":"https://ror.org/03pvyf116","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210134579"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Reyhan Gedik","raw_affiliation_strings":["Harvard - MGH,Dept. of Pathology","Dept. of Pathology, Harvard - MGH"],"affiliations":[{"raw_affiliation_string":"Harvard - MGH,Dept. of Pathology","institution_ids":["https://openalex.org/I4210134579","https://openalex.org/I4210156643"]},{"raw_affiliation_string":"Dept. of Pathology, Harvard - MGH","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013695426","display_name":"Bar\u0131\u015f Co\u015fkunuzer","orcid":"https://orcid.org/0000-0001-7462-8819"},"institutions":[{"id":"https://openalex.org/I162577319","display_name":"The University of Texas at Dallas","ror":"https://ror.org/049emcs32","country_code":"US","type":"education","lineage":["https://openalex.org/I162577319"]},{"id":"https://openalex.org/I87573096","display_name":"University of North Texas at Dallas","ror":"https://ror.org/01n51v443","country_code":"US","type":"education","lineage":["https://openalex.org/I87573096"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Baris Coskunuzer","raw_affiliation_strings":["U. Texas at Dallas,Dept. of Math. Sciences","Dept. of Math. Sciences, U. Texas at Dallas"],"affiliations":[{"raw_affiliation_string":"U. Texas at Dallas,Dept. of Math. Sciences","institution_ids":["https://openalex.org/I162577319","https://openalex.org/I87573096"]},{"raw_affiliation_string":"Dept. of Math. Sciences, U. Texas at Dallas","institution_ids":["https://openalex.org/I162577319"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5102819816"],"corresponding_institution_ids":["https://openalex.org/I162577319","https://openalex.org/I3169584401","https://openalex.org/I4210094379","https://openalex.org/I87573096"],"apc_list":null,"apc_paid":null,"fwci":3.244,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.93510383,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":null,"issue":null,"first_page":"1610","last_page":"1619"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12536","display_name":"Topological and Geometric Data Analysis","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12536","display_name":"Topological and Geometric Data Analysis","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9861999750137329,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/topological-data-analysis","display_name":"Topological data analysis","score":0.6677662134170532},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.654078483581543},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.5172708630561829},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5110827684402466},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.4592542350292206},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.45527902245521545},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4169886112213135},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.1812206208705902}],"concepts":[{"id":"https://openalex.org/C2776477805","wikidata":"https://www.wikidata.org/wiki/Q4460773","display_name":"Topological data analysis","level":2,"score":0.6677662134170532},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.654078483581543},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.5172708630561829},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5110827684402466},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.4592542350292206},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.45527902245521545},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4169886112213135},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.1812206208705902},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm58861.2023.10385822","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm58861.2023.10385822","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306164","display_name":"Simons Foundation","ror":"https://ror.org/01cmst727"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W1528911722","https://openalex.org/W1753705553","https://openalex.org/W1820655337","https://openalex.org/W2003660259","https://openalex.org/W2039051707","https://openalex.org/W2044465660","https://openalex.org/W2097290407","https://openalex.org/W2102372511","https://openalex.org/W2136883589","https://openalex.org/W2154477220","https://openalex.org/W2190682267","https://openalex.org/W2216562547","https://openalex.org/W2332913015","https://openalex.org/W2548197316","https://openalex.org/W2616161726","https://openalex.org/W2716665989","https://openalex.org/W2761733590","https://openalex.org/W2805860889","https://openalex.org/W2807103388","https://openalex.org/W2807416830","https://openalex.org/W2885824038","https://openalex.org/W2892046320","https://openalex.org/W2935748854","https://openalex.org/W2945006865","https://openalex.org/W2949226441","https://openalex.org/W2949721846","https://openalex.org/W2959970591","https://openalex.org/W2962934138","https://openalex.org/W2963129226","https://openalex.org/W2980929630","https://openalex.org/W2995942064","https://openalex.org/W2997214020","https://openalex.org/W3006726090","https://openalex.org/W3014603530","https://openalex.org/W3035517588","https://openalex.org/W3038704997","https://openalex.org/W3089090082","https://openalex.org/W3098455240","https://openalex.org/W3113328935","https://openalex.org/W3130936001","https://openalex.org/W3160261825","https://openalex.org/W3164241150","https://openalex.org/W3169982119","https://openalex.org/W3180014654","https://openalex.org/W3181029726","https://openalex.org/W3194164694","https://openalex.org/W3197288968","https://openalex.org/W3202868818","https://openalex.org/W3204788326","https://openalex.org/W3211074487","https://openalex.org/W4212811301","https://openalex.org/W4212984849","https://openalex.org/W4213033583","https://openalex.org/W4214861559","https://openalex.org/W4225271072","https://openalex.org/W4285024288","https://openalex.org/W4285579170","https://openalex.org/W4386275867","https://openalex.org/W6779661468","https://openalex.org/W6802962544"],"related_works":["https://openalex.org/W2601157893","https://openalex.org/W2131735617","https://openalex.org/W2373006798","https://openalex.org/W2056912418","https://openalex.org/W2123759770","https://openalex.org/W2033213769","https://openalex.org/W2811390910","https://openalex.org/W4312376745","https://openalex.org/W2082269393","https://openalex.org/W2043960970"],"abstract_inverted_index":{"We":[0],"present":[1],"a":[2,13,164],"transformative":[3],"approach":[4],"to":[5,53,61,101],"histopathological":[6,50],"cancer":[7,119],"detection":[8],"and":[9,79,104,127,147],"grading":[10],"by":[11],"introducing":[12],"very":[14,77,157],"powerful":[15],"feature":[16,55],"extraction":[17],"method":[18],"based":[19],"on":[20,114,150],"the":[21,29,111],"latest":[22],"topological":[23,32,47,66],"data":[24,142],"analysis":[25],"tools.":[26],"By":[27],"analyzing":[28],"evolution":[30],"of":[31,95,170,172],"patterns":[33],"in":[34,49,83],"different":[35,102],"color":[36],"channels,":[37],"we":[38],"discovered":[39],"that":[40,57],"every":[41],"tumor":[42,64],"class":[43],"leaves":[44],"its":[45],"own":[46],"footprint":[48],"images,":[51],"allowing":[52],"extract":[54],"vectors":[56],"can":[58],"be":[59],"used":[60],"reliably":[62],"identify":[63],"classes.Our":[65],"signatures,":[67],"even":[68],"when":[69],"combined":[70],"with":[71,110,159],"traditional":[72],"machine":[73],"learning":[74],"methods,":[75],"provide":[76],"fast":[78],"highly":[80,107],"accurate":[81],"results":[82,109],"various":[84],"settings.":[85],"While":[86],"most":[87,131],"DL":[88,132],"models":[89,113],"work":[90],"well":[91],"for":[92,167],"one":[93],"type":[94],"cancer,":[96],"our":[97,134],"model":[98,137,154],"easily":[99],"adapts":[100],"scenarios,":[103],"consistently":[105],"gives":[106],"competitive":[108],"state-of-the-art":[112],"benchmark":[115],"datasets":[116,168],"across":[117],"multiple":[118],"types":[120],"including":[121],"bone,":[122],"colon,":[123],"breast,":[124],"cervical":[125],"(cytopathology),":[126],"prostate":[128],"cancer.":[129],"Unlike":[130],"models,":[133],"proposed":[135],"Topo-ML":[136],"does":[138],"not":[139],"need":[140],"any":[141],"augmentation":[143],"or":[144],"pre-processing":[145],"steps":[146],"works":[148],"perfectly":[149],"small":[151],"datasets.":[152],"The":[153],"is":[155],"computationally":[156],"efficient,":[158],"end-to-end":[160],"processing":[161],"taking":[162],"only":[163],"few":[165],"hours":[166],"consisting":[169],"thousands":[171],"images.":[173]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":2}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2025-10-10T00:00:00"}
