{"id":"https://openalex.org/W4313527286","doi":"https://doi.org/10.1109/bibm55620.2022.9994981","title":"Predicting miRNA-disease associations via multi-channel graph convolutional networks","display_name":"Predicting miRNA-disease associations via multi-channel graph convolutional networks","publication_year":2022,"publication_date":"2022-12-06","ids":{"openalex":"https://openalex.org/W4313527286","doi":"https://doi.org/10.1109/bibm55620.2022.9994981"},"language":"en","primary_location":{"id":"doi:10.1109/bibm55620.2022.9994981","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/bibm55620.2022.9994981","pdf_url":null,"source":{"id":"https://openalex.org/S4363607730","display_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058370781","display_name":"HaoRan Zheng","orcid":null},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I3130607311","display_name":"Changsha Normal University","ror":"https://ror.org/02sqk3z62","country_code":"CN","type":"education","lineage":["https://openalex.org/I3130607311"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"HaoRan Zheng","raw_affiliation_strings":["Hunan Normal University,College of Information Science and Engineering,Changsha,China","College of Information Science and Engineering, Hunan Normal University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hunan Normal University,College of Information Science and Engineering,Changsha,China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I3130607311"]},{"raw_affiliation_string":"College of Information Science and Engineering, Hunan Normal University, Changsha, China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I3130607311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086050506","display_name":"Qiu Xiao","orcid":"https://orcid.org/0000-0002-4726-7154"},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiu Xiao","raw_affiliation_strings":["Hunan Normal University,MOE-LCSM,School of Mathematics and Statistics,Changsha,China","MOE-LCSM,School of Mathematics and Statistics, Hunan Normal University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hunan Normal University,MOE-LCSM,School of Mathematics and Statistics,Changsha,China","institution_ids":["https://openalex.org/I173759888"]},{"raw_affiliation_string":"MOE-LCSM,School of Mathematics and Statistics, Hunan Normal University, Changsha, China","institution_ids":["https://openalex.org/I173759888"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033371544","display_name":"Jiancheng Zhong","orcid":"https://orcid.org/0000-0001-6334-9304"},"institutions":[{"id":"https://openalex.org/I173759888","display_name":"Hunan Normal University","ror":"https://ror.org/053w1zy07","country_code":"CN","type":"education","lineage":["https://openalex.org/I173759888"]},{"id":"https://openalex.org/I3130607311","display_name":"Changsha Normal University","ror":"https://ror.org/02sqk3z62","country_code":"CN","type":"education","lineage":["https://openalex.org/I3130607311"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"JianCheng Zhong","raw_affiliation_strings":["Hunan Normal University,College of Information Science and Engineering,Changsha,China","College of Information Science and Engineering, Hunan Normal University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hunan Normal University,College of Information Science and Engineering,Changsha,China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I3130607311"]},{"raw_affiliation_string":"College of Information Science and Engineering, Hunan Normal University, Changsha, China","institution_ids":["https://openalex.org/I173759888","https://openalex.org/I3130607311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28824834,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"700","last_page":"705"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6383825540542603},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.6132392883300781},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5274995565414429},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.48163074254989624},{"id":"https://openalex.org/keywords/network-topology","display_name":"Network topology","score":0.4566255807876587},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.44811493158340454},{"id":"https://openalex.org/keywords/graph-theory","display_name":"Graph theory","score":0.41467198729515076},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.35475873947143555},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.33018261194229126},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.31180083751678467},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.16288691759109497},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.14819014072418213},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1304958462715149}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6383825540542603},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.6132392883300781},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5274995565414429},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.48163074254989624},{"id":"https://openalex.org/C199845137","wikidata":"https://www.wikidata.org/wiki/Q145490","display_name":"Network topology","level":2,"score":0.4566255807876587},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.44811493158340454},{"id":"https://openalex.org/C88230418","wikidata":"https://www.wikidata.org/wiki/Q131476","display_name":"Graph theory","level":2,"score":0.41467198729515076},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35475873947143555},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.33018261194229126},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.31180083751678467},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16288691759109497},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14819014072418213},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1304958462715149},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm55620.2022.9994981","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/bibm55620.2022.9994981","pdf_url":null,"source":{"id":"https://openalex.org/S4363607730","display_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W2002853429","https://openalex.org/W2044351959","https://openalex.org/W2088252378","https://openalex.org/W2103151642","https://openalex.org/W2106029302","https://openalex.org/W2128768066","https://openalex.org/W2141222510","https://openalex.org/W2158135353","https://openalex.org/W2604314403","https://openalex.org/W2805684402","https://openalex.org/W2805876954","https://openalex.org/W2888881065","https://openalex.org/W2889119877","https://openalex.org/W2890764580","https://openalex.org/W2898949455","https://openalex.org/W2903219977","https://openalex.org/W2903730942","https://openalex.org/W2910272722","https://openalex.org/W2924501502","https://openalex.org/W2945357511","https://openalex.org/W2948726969","https://openalex.org/W2964015378","https://openalex.org/W2964951118","https://openalex.org/W2979975313","https://openalex.org/W2993347499","https://openalex.org/W3011689400","https://openalex.org/W3039075121","https://openalex.org/W3046022368","https://openalex.org/W3080991592","https://openalex.org/W3100993589","https://openalex.org/W3124226459","https://openalex.org/W3143789190","https://openalex.org/W3157315991","https://openalex.org/W3157330827","https://openalex.org/W3159261411","https://openalex.org/W3195255252","https://openalex.org/W3198879735","https://openalex.org/W4200043367","https://openalex.org/W4210607727","https://openalex.org/W4211064852","https://openalex.org/W4225752318","https://openalex.org/W4281553978","https://openalex.org/W6726873649"],"related_works":["https://openalex.org/W2086397253","https://openalex.org/W2133122801","https://openalex.org/W600422426","https://openalex.org/W2007156430","https://openalex.org/W1982032334","https://openalex.org/W4385627933","https://openalex.org/W2532801570","https://openalex.org/W2480127678","https://openalex.org/W2806270048","https://openalex.org/W4310605282"],"abstract_inverted_index":{"Extensive":[0],"research":[1,34,72],"evidence":[2],"shows":[3],"that":[4,143,162],"variation":[5],"and":[6,15,25,35,41,91,115,136],"dysregulation":[7],"of":[8,13,19,31,43,70,82,122,166,183],"microRNAs(miRNAs)":[9],"are":[10],"important":[11,23],"causes":[12],"disease,":[14],"therefore":[16],"the":[17,29,39,68,113,163,180],"study":[18,102],"miRNA-disease":[20,45,59],"associations":[21,46,60],"has":[22,62],"theoretical":[24],"applied":[26],"implications":[27],"in":[28,47,67,73],"field":[30,69],"human":[32,193],"disease":[33],"treatment.":[36],"Based":[37,97],"on":[38,85,98],"time":[40],"cost":[42],"validating":[44],"traditional":[48],"medicine":[49],"clinical":[50],"experiments,":[51],"using":[52],"multiple":[53],"biological":[54,71],"datasets":[55],"to":[56,140,185],"predict":[57],"potential":[58,187],"(MDAs)":[61],"become":[63],"a":[64,79,86,107,151,154],"hot":[65],"topic":[66],"recent":[74],"years.":[75],"This":[76],"paper":[77],"develops":[78],"novel":[80],"model":[81],"MDA-RGCN":[83,167,184],"based":[84],"multi-channel":[87],"graph":[88,92,99,120,129],"convolutional":[89],"network":[90],"attention":[93,130],"for":[94,173,195],"MDAs":[95,104,174],"prediction.":[96,175],"theory,":[100],"this":[101],"treats":[103],"prediction":[105,164],"as":[106],"node":[108],"classification":[109],"task.":[110],"To":[111],"learn":[112,141],"topology":[114],"various":[116,123],"interactions":[117],"between":[118],"feature":[119],"nodes":[121],"strengths,":[124],"we":[125,149,177],"employ":[126,150],"two":[127,192],"independent":[128],"networks,":[131],"which":[132],"increases":[133],"training":[134],"efficiency":[135],"accuracy.":[137],"In":[138],"order":[139],"information":[142],"is":[144],"shared":[145,155],"by":[146,190],"both":[147],"graphs,":[148],"GCN":[152],"with":[153],"weight":[156],"matrix":[157],"simultaneously.":[158],"Comprehensive":[159],"experiments":[160],"reveal":[161],"performance":[165],"excels":[168],"other":[169],"more":[170],"sophisticated":[171],"models":[172],"Furthermore,":[176],"further":[178],"confirmed":[179],"predictive":[181],"ability":[182],"identify":[186],"disease-related":[188],"miRNAs":[189],"selecting":[191],"diseases":[194],"case":[196],"study.":[197]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}