{"id":"https://openalex.org/W4313413300","doi":"https://doi.org/10.1109/bibm55620.2022.9994891","title":"NOMA-DB: a framework for management and analysis of ageing-related gene-expression data","display_name":"NOMA-DB: a framework for management and analysis of ageing-related gene-expression data","publication_year":2022,"publication_date":"2022-12-06","ids":{"openalex":"https://openalex.org/W4313413300","doi":"https://doi.org/10.1109/bibm55620.2022.9994891"},"language":"en","primary_location":{"id":"doi:10.1109/bibm55620.2022.9994891","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/bibm55620.2022.9994891","pdf_url":null,"source":{"id":"https://openalex.org/S4363607730","display_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037399554","display_name":"Pietro Hiram Guzzi","orcid":"https://orcid.org/0000-0001-5542-2997"},"institutions":[{"id":"https://openalex.org/I36443711","display_name":"Magna Graecia University","ror":"https://ror.org/0530bdk91","country_code":"IT","type":"education","lineage":["https://openalex.org/I36443711"]},{"id":"https://openalex.org/I4210133179","display_name":"Accademia di Belle Arti di Catanzaro","ror":"https://ror.org/0459rb715","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210133179"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Pietro Hiram Guzzi","raw_affiliation_strings":["University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","institution_ids":["https://openalex.org/I36443711","https://openalex.org/I4210133179"]},{"raw_affiliation_string":"Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy","institution_ids":["https://openalex.org/I36443711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059223728","display_name":"Ugo Lomoio","orcid":"https://orcid.org/0000-0001-8150-0039"},"institutions":[{"id":"https://openalex.org/I36443711","display_name":"Magna Graecia University","ror":"https://ror.org/0530bdk91","country_code":"IT","type":"education","lineage":["https://openalex.org/I36443711"]},{"id":"https://openalex.org/I4210133179","display_name":"Accademia di Belle Arti di Catanzaro","ror":"https://ror.org/0459rb715","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210133179"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ugo Lomoio","raw_affiliation_strings":["University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","institution_ids":["https://openalex.org/I36443711","https://openalex.org/I4210133179"]},{"raw_affiliation_string":"Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy","institution_ids":["https://openalex.org/I36443711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025840718","display_name":"Rocco Scicchitano","orcid":null},"institutions":[{"id":"https://openalex.org/I36443711","display_name":"Magna Graecia University","ror":"https://ror.org/0530bdk91","country_code":"IT","type":"education","lineage":["https://openalex.org/I36443711"]},{"id":"https://openalex.org/I4210133179","display_name":"Accademia di Belle Arti di Catanzaro","ror":"https://ror.org/0459rb715","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210133179"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rocco Scicchitano","raw_affiliation_strings":["University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","institution_ids":["https://openalex.org/I36443711","https://openalex.org/I4210133179"]},{"raw_affiliation_string":"Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy","institution_ids":["https://openalex.org/I36443711"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027369094","display_name":"Pierangelo Veltri","orcid":"https://orcid.org/0000-0003-2494-0294"},"institutions":[{"id":"https://openalex.org/I36443711","display_name":"Magna Graecia University","ror":"https://ror.org/0530bdk91","country_code":"IT","type":"education","lineage":["https://openalex.org/I36443711"]},{"id":"https://openalex.org/I4210133179","display_name":"Accademia di Belle Arti di Catanzaro","ror":"https://ror.org/0459rb715","country_code":"IT","type":"education","lineage":["https://openalex.org/I4210133179"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Pierangelo Veltri","raw_affiliation_strings":["University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Catanzaro,Dept. Surgical and Medical Sciences,Catanzaro,Italy","institution_ids":["https://openalex.org/I36443711","https://openalex.org/I4210133179"]},{"raw_affiliation_string":"Dept. Surgical and Medical Sciences, University of Catanzaro, Catanzaro, Italy","institution_ids":["https://openalex.org/I36443711"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7581,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.86703383,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"1905","last_page":"1910"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7271029949188232},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.6032251119613647},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.48647019267082214},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.08235400915145874}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7271029949188232},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.6032251119613647},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.48647019267082214},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.08235400915145874}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm55620.2022.9994891","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1109/bibm55620.2022.9994891","pdf_url":null,"source":{"id":"https://openalex.org/S4363607730","display_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/5","display_name":"Gender equality","score":0.4099999964237213}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1507181850","https://openalex.org/W1590379080","https://openalex.org/W1737180198","https://openalex.org/W1974219242","https://openalex.org/W2008880771","https://openalex.org/W2018838463","https://openalex.org/W2029382089","https://openalex.org/W2048605133","https://openalex.org/W2075773171","https://openalex.org/W2107640794","https://openalex.org/W2108700752","https://openalex.org/W2136605542","https://openalex.org/W2151807108","https://openalex.org/W2161174387","https://openalex.org/W2415866521","https://openalex.org/W2592659532","https://openalex.org/W2736788078","https://openalex.org/W2739438570","https://openalex.org/W2752701793","https://openalex.org/W2764200887","https://openalex.org/W2767517408","https://openalex.org/W2788953364","https://openalex.org/W2792808664","https://openalex.org/W2898528741","https://openalex.org/W2922246663","https://openalex.org/W2939945403","https://openalex.org/W2988912149","https://openalex.org/W3016556691","https://openalex.org/W3017299963","https://openalex.org/W3022432727","https://openalex.org/W3033571825","https://openalex.org/W3096294596","https://openalex.org/W3129795799","https://openalex.org/W3131708129","https://openalex.org/W3186506153","https://openalex.org/W3191857354","https://openalex.org/W3194780475","https://openalex.org/W3199660015","https://openalex.org/W3208629828","https://openalex.org/W3213403904","https://openalex.org/W4205648805","https://openalex.org/W4213126664","https://openalex.org/W4214721934","https://openalex.org/W4283016888","https://openalex.org/W4286697753"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052","https://openalex.org/W4402327032","https://openalex.org/W2382290278"],"abstract_inverted_index":{"Recently":[0],"there":[1],"is":[2,42,189],"a":[3,67,114,164],"growing":[4],"interest":[5],"for":[6,30,48,109,137,166],"the":[7,10,18,35,37,45,49,64,78,86,90,96,111,127,135,138,152,174,193,212,241],"study":[8],"of":[9,13,44,51,63,69,80,113,140,151,173,205,214,230,235,243],"molecular":[11,32,237],"basis":[12],"ageing":[14,167],"processes":[15,238],"and":[16,28,58,102,145,157,196,219],"on":[17,77,82,89,117,126,170,191,197,203,240],"differences":[19],"among":[20],"genders.":[21],"These":[22],"studies":[23,168],"require":[24],"many":[25,74,121],"data,":[26],"models":[27],"tools":[29,141],"inferring":[31],"mechanisms.":[33],"Among":[34],"others,":[36],"Genotype-Tissue":[38],"Expression":[39],"(GTEx)":[40],"database":[41,65,87,176,195],"one":[43],"prominent":[46],"resources":[47],"analysis":[50,75,91,147,156,213,231,242],"expression":[52,79,112,244],"data":[53,101],"related":[54],"to":[55,99],"tissues,":[56],"sex":[57],"age.":[59],"The":[60,187,208],"current":[61,209],"version":[62,210],"has":[66,98],"lot":[68],"querying":[70,180],"interfaces":[71],"that":[72,177],"enable":[73,178],"centred":[76],"genes":[81,215],"tissues.":[83],"Despite":[84],"this,":[85],"lacks":[88,125],"at":[92,181],"sex/age":[93,182],"level,":[94,183],"thus":[95,221],"researcher":[97],"download":[100],"then":[103],"write":[104],"queries":[105],"by":[106,216],"hand":[107],"(e.g.":[108],"retrieving":[110],"given":[115],"gene":[116,218],"different":[118],"age-class":[119],"in":[120,226],"tissues).":[122],"It":[123],"also":[124],"integration":[128],"with":[129],"existing":[130,206],"protein":[131],"interaction":[132],"data.":[133,207,245],"Therefore,":[134],"need":[136],"introduction":[139],"enabling":[142],"easy":[143,179],"access":[144],"powerful":[146],"capabilities":[148],"(i.e.":[149],"state":[150],"art":[153],"network":[154,184],"based":[155,169,185,190,239],"integration),":[158],"arises.":[159],"We":[160],"here":[161],"present":[162],"NOMA-DB,":[163],"framework":[165,188],"an":[171,199],"extension":[172],"GTEx":[175,194],"analysis.":[186],"wrapping":[192],"building":[198],"application":[200],"logic":[201],"level":[202],"top":[204],"enables":[211],"tissue,":[217],"age,":[220],"it":[222],"may":[223],"be":[224],"used":[225],"potentially":[227],"future":[228],"directions":[229],"towards":[232],"better":[233],"comprehension":[234],"aging/sex-related":[236]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3}],"updated_date":"2025-12-23T23:11:35.936235","created_date":"2025-10-10T00:00:00"}