{"id":"https://openalex.org/W4205993940","doi":"https://doi.org/10.1109/bibm52615.2021.9669144","title":"CellDet: Dual-Task Cell Detection Network for IHC-Stained Image Analysis","display_name":"CellDet: Dual-Task Cell Detection Network for IHC-Stained Image Analysis","publication_year":2021,"publication_date":"2021-12-09","ids":{"openalex":"https://openalex.org/W4205993940","doi":"https://doi.org/10.1109/bibm52615.2021.9669144"},"language":"en","primary_location":{"id":"doi:10.1109/bibm52615.2021.9669144","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm52615.2021.9669144","pdf_url":null,"source":{"id":"https://openalex.org/S4363607735","display_name":"2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061671391","display_name":"Wei Ji","orcid":"https://orcid.org/0000-0002-8570-7253"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Ji","raw_affiliation_strings":["School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110964104","display_name":"Weiwei Tian","orcid":"https://orcid.org/0000-0002-3725-8457"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weiwei Tian","raw_affiliation_strings":["Academy for Engineering and Technology, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academy for Engineering and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022044577","display_name":"Wen\u2010Bin Pan","orcid":null},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenbin Pan","raw_affiliation_strings":["School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102008661","display_name":"Siqi Sun","orcid":"https://orcid.org/0009-0007-7298-7288"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siqi Sun","raw_affiliation_strings":["School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100742769","display_name":"Hui Jiang","orcid":"https://orcid.org/0000-0003-3972-1297"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Jiang","raw_affiliation_strings":["Changhai Hospital, Navy Military Medical University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Changhai Hospital, Navy Military Medical University, Shanghai, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101860531","display_name":"Rui Feng","orcid":"https://orcid.org/0000-0001-6648-953X"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Feng","raw_affiliation_strings":["Academy for Engineering and Technology, Fudan University, Shanghai, China","School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academy for Engineering and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]},{"raw_affiliation_string":"School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070073283","display_name":"Yuejie Zhang","orcid":"https://orcid.org/0000-0001-7993-7223"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuejie Zhang","raw_affiliation_strings":["School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science, Shanghai Key Laboratory of Intelligent Information Processing, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100626035","display_name":"Rui-Wei Zhao","orcid":"https://orcid.org/0000-0002-8498-5761"},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui-Wei Zhao","raw_affiliation_strings":["Academy for Engineering and Technology, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academy for Engineering and Technology, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073844760","display_name":"Gang Jin","orcid":"https://orcid.org/0000-0001-6713-1185"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gang Jin","raw_affiliation_strings":["Changhai Hospital, Navy Military Medical University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Changhai Hospital, Navy Military Medical University, Shanghai, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":null,"first_page":"1343","last_page":"1346"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8306618928909302},{"id":"https://openalex.org/keywords/minimum-bounding-box","display_name":"Minimum bounding box","score":0.7206923961639404},{"id":"https://openalex.org/keywords/pyramid","display_name":"Pyramid (geometry)","score":0.6375772356987},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5949944257736206},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5360448956489563},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.5306412577629089},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5057272911071777},{"id":"https://openalex.org/keywords/object-detection","display_name":"Object detection","score":0.5054903030395508},{"id":"https://openalex.org/keywords/bounding-overwatch","display_name":"Bounding overwatch","score":0.5011920928955078},{"id":"https://openalex.org/keywords/margin","display_name":"Margin (machine learning)","score":0.4762142598628998},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.462788850069046},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.43787702918052673},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.37752118706703186},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.2090858817100525}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8306618928909302},{"id":"https://openalex.org/C147037132","wikidata":"https://www.wikidata.org/wiki/Q6865426","display_name":"Minimum bounding box","level":3,"score":0.7206923961639404},{"id":"https://openalex.org/C142575187","wikidata":"https://www.wikidata.org/wiki/Q3358290","display_name":"Pyramid (geometry)","level":2,"score":0.6375772356987},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5949944257736206},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5360448956489563},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.5306412577629089},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5057272911071777},{"id":"https://openalex.org/C2776151529","wikidata":"https://www.wikidata.org/wiki/Q3045304","display_name":"Object detection","level":3,"score":0.5054903030395508},{"id":"https://openalex.org/C63584917","wikidata":"https://www.wikidata.org/wiki/Q333286","display_name":"Bounding overwatch","level":2,"score":0.5011920928955078},{"id":"https://openalex.org/C774472","wikidata":"https://www.wikidata.org/wiki/Q6760393","display_name":"Margin (machine learning)","level":2,"score":0.4762142598628998},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.462788850069046},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.43787702918052673},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.37752118706703186},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2090858817100525},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm52615.2021.9669144","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm52615.2021.9669144","pdf_url":null,"source":{"id":"https://openalex.org/S4363607735","display_name":"2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2021 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6399999856948853,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W2026893473","https://openalex.org/W2034980306","https://openalex.org/W2088674746","https://openalex.org/W2150134401","https://openalex.org/W2347064614","https://openalex.org/W2565639579","https://openalex.org/W2630837129","https://openalex.org/W2810313146","https://openalex.org/W2901331091","https://openalex.org/W2909488080","https://openalex.org/W2962449912","https://openalex.org/W2963351448","https://openalex.org/W2963587345","https://openalex.org/W2979154526","https://openalex.org/W2984155152","https://openalex.org/W2989604896","https://openalex.org/W2997747012","https://openalex.org/W3042011474","https://openalex.org/W3093046161","https://openalex.org/W3128065691","https://openalex.org/W3133153571","https://openalex.org/W3155775787","https://openalex.org/W6739696289","https://openalex.org/W6752445296","https://openalex.org/W6756432900","https://openalex.org/W6758253779","https://openalex.org/W6760424586"],"related_works":["https://openalex.org/W4237171675","https://openalex.org/W3036286480","https://openalex.org/W4287027631","https://openalex.org/W3192357901","https://openalex.org/W2387360586","https://openalex.org/W2952736415","https://openalex.org/W3209723314","https://openalex.org/W3205398323","https://openalex.org/W2883297582","https://openalex.org/W4390524233"],"abstract_inverted_index":{"Cell":[0],"detection":[1,24,38,146],"on":[2],"immunohistochemistry":[3],"stained":[4],"(IHC-stained)":[5],"images":[6],"plays":[7],"an":[8],"essential":[9],"role":[10],"in":[11,69,160],"computer":[12],"assisted":[13],"prediction":[14],"of":[15,67],"tumor":[16],"progression":[17],"and":[18,93,108,158],"treatment":[19],"response.":[20],"Currently":[21],"available":[22],"cell":[23,145],"datasets":[25],"provide":[26],"either":[27],"point":[28,107],"level":[29,33],"or":[30],"bounding":[31,109,131],"box":[32,110,132],"annotations":[34],"for":[35],"deep":[36],"object":[37],"network":[39,84],"training.":[40],"And":[41],"these":[42,58],"widely":[43],"used":[44],"networks":[45],"usually":[46],"employ":[47],"standard":[48],"pyramid":[49],"structured":[50],"multi-scale":[51],"feature":[52],"fusion.":[53],"However,":[54],"we":[55,79],"find":[56],"that":[57,138],"methods":[59,147],"have":[60],"obvious":[61],"limitation":[62],"when":[63],"facing":[64],"large":[65],"amounts":[66],"cells":[68],"similar":[70],"scale":[71],"with":[72,85,130,148],"severe":[73],"overlapping.":[74],"To":[75],"address":[76],"this":[77],"problem,":[78],"propose":[80],"a":[81,149],"novel":[82],"CellDet":[83,141],"(1)":[86],"Scale":[87],"Consistency":[88],"Feature":[89],"Fusion":[90],"Module":[91,98],"(SCFFM)":[92],"(2)":[94],"Dual":[95],"Task":[96],"Detection":[97],"to":[99,114,124],"simultaneously":[100],"exploit":[101],"the":[102,116,126,139],"complementary":[103],"information":[104],"from":[105],"both":[106],"annotations.":[111,133],"In":[112],"order":[113],"verify":[115],"effectiveness":[117],"our":[118,155],"proposed":[119,140],"method,":[120],"We":[121,152],"make":[122],"efforts":[123],"relabel":[125],"public":[127],"SHIDC-B-Ki-67":[128],"dataset":[129,159],"Extensive":[134],"experimental":[135],"results":[136],"show":[137],"outperforms":[142],"other":[143],"state-of-the-art":[144],"remarkable":[150],"margin.":[151],"will":[153],"release":[154],"source":[156],"code":[157],"https://github.com/JiweiMaster/celldet.":[161]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}