{"id":"https://openalex.org/W3004540857","doi":"https://doi.org/10.1109/bibm47256.2019.8983192","title":"GSDcreator: An Efficient and Comprehensive Simulator for Genarating NGS Data with Population Genetic Information","display_name":"GSDcreator: An Efficient and Comprehensive Simulator for Genarating NGS Data with Population Genetic Information","publication_year":2019,"publication_date":"2019-11-01","ids":{"openalex":"https://openalex.org/W3004540857","doi":"https://doi.org/10.1109/bibm47256.2019.8983192","mag":"3004540857"},"language":"en","primary_location":{"id":"doi:10.1109/bibm47256.2019.8983192","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm47256.2019.8983192","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5115694725","display_name":"Shenjie Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shenjie Wang","raw_affiliation_strings":["Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027360778","display_name":"Jiayin Wang","orcid":"https://orcid.org/0000-0002-3862-6557"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiayin Wang","raw_affiliation_strings":["Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451727","display_name":"Xiao Xiao","orcid":"https://orcid.org/0000-0002-4328-0634"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao Xiao","raw_affiliation_strings":["School of Public Policy and Administration, Xi'an Jiaotong University,Xi'an,Shaanxi,China,710049","School of Public Policy and Administration, Xi'an Jiaotong University, Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Public Policy and Administration, Xi'an Jiaotong University,Xi'an,Shaanxi,China,710049","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"School of Public Policy and Administration, Xi'an Jiaotong University, Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115594780","display_name":"Xuanping Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuanping Zhang","raw_affiliation_strings":["Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054657033","display_name":"Xuwen Wang","orcid":"https://orcid.org/0000-0003-3022-6513"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuwen Wang","raw_affiliation_strings":["Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100452974","display_name":"Xiaoyan Zhu","orcid":"https://orcid.org/0000-0002-7173-7793"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyan Zhu","raw_affiliation_strings":["Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047344339","display_name":"Xin Lai","orcid":"https://orcid.org/0000-0003-3850-5680"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Lai","raw_affiliation_strings":["Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Shaanxi Engineering Research Center of Medical and Health Big Data, Xi'an Jiaotong University","institution_ids":["https://openalex.org/I87445476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.171,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.54405558,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"1868","last_page":"1875"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":0.9879000186920166,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9854999780654907,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7681839466094971},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.6281505823135376},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5918598771095276},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5865459442138672},{"id":"https://openalex.org/keywords/data-quality","display_name":"Data quality","score":0.47760888934135437},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.32182687520980835},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08710554242134094}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7681839466094971},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.6281505823135376},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5918598771095276},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5865459442138672},{"id":"https://openalex.org/C24756922","wikidata":"https://www.wikidata.org/wiki/Q1757694","display_name":"Data quality","level":3,"score":0.47760888934135437},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.32182687520980835},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08710554242134094},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.0},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm47256.2019.8983192","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm47256.2019.8983192","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1650156802","https://openalex.org/W1987069789","https://openalex.org/W1993805321","https://openalex.org/W2024789434","https://openalex.org/W2046601740","https://openalex.org/W2048818637","https://openalex.org/W2097331151","https://openalex.org/W2103962160","https://openalex.org/W2110374888","https://openalex.org/W2119180969","https://openalex.org/W2126838526","https://openalex.org/W2126948011","https://openalex.org/W2139570101","https://openalex.org/W2140888103","https://openalex.org/W2141978199","https://openalex.org/W2146005104","https://openalex.org/W2153762432","https://openalex.org/W2153993827","https://openalex.org/W2154397429","https://openalex.org/W2157539385","https://openalex.org/W2194510225","https://openalex.org/W2230465815","https://openalex.org/W2467325308","https://openalex.org/W2785110924"],"related_works":["https://openalex.org/W2578341013","https://openalex.org/W3162731545","https://openalex.org/W2137479650","https://openalex.org/W2245479382","https://openalex.org/W2135768893","https://openalex.org/W3139296374","https://openalex.org/W176219849","https://openalex.org/W3021414116","https://openalex.org/W4387803644","https://openalex.org/W4210350690"],"abstract_inverted_index":{"In":[0,86,103],"recent":[1],"decades,":[2],"NGS":[3,31,51,111],"data":[4,52,143,203],"analysis":[5],"has":[6],"become":[7],"a":[8,48,109,178,195],"major":[9],"research":[10],"field":[11],"in":[12,18],"bioinformatics,":[13],"which":[14],"presents":[15],"great":[16],"advantages":[17],"many":[19,66,74,140],"application":[20],"scenarios.":[21,68],"Many":[22],"algorithms":[23],"and":[24,42,165,180,199],"software":[25,41],"were":[26],"designed":[27],"for":[28,39],"analyzing":[29],"the":[30,58,63,90,115,129,191,211],"data,":[32,94],"while":[33],"simulation":[34],"datasets":[35],"are":[36,82,133,207],"urgently":[37],"needed":[38],"testing":[40],"optimizing":[43],"their":[44],"parameter":[45],"configurations.":[46],"Thus,":[47],"series":[49],"of":[50,92,126,131,197],"simulators":[53,60],"have":[54],"been":[55],"published.":[56],"However,":[57],"existing":[59],"cannot":[61],"satisfy":[62],"requirements":[64],"from":[65],"specific":[67],"First,":[69],"they":[70],"do":[71],"not":[72],"support":[73],"newly":[75],"discovered":[76],"variations.":[77],"Second,":[78],"complex":[79,130],"structural":[80],"variations":[81,132],"difficult":[83],"to":[84,98,185,210],"generate.":[85],"addition,":[87],"along":[88],"with":[89],"increase":[91,99],"population":[93,100,146,182,187],"it":[95,137],"is":[96,175],"urgent":[97],"information":[101,184],"simulation.":[102],"this":[104],"paper,":[105],"we":[106,193],"propose":[107],"GSDcreator,":[108],"comprehensive":[110],"simulator":[112],"that":[113,170,201],"overcome":[114],"three":[116],"weaknesses":[117],"mentioned":[118],"above.":[119],"It":[120],"can":[121,138],"produce":[122],"all":[123],"known":[124],"types":[125],"variation,":[127],"where":[128],"also":[134],"supported.":[135],"Furthermore,":[136],"capture":[139],"important":[141],"real":[142,212],"features":[144],"including":[145],"polymorphism,":[147],"insert":[148],"size":[149],"distribution,":[150,154,157,160],"adjacent":[151],"site":[152],"depth":[153,156],"overall":[155],"quality":[158],"score":[159],"amplification":[161],"bias,":[162],"sequencing":[163,213],"errors":[164],"so":[166],"on.":[167],"It's":[168],"highlighted":[169],"1000":[171],"Genomes":[172],"Project":[173],"Database":[174],"taken":[176],"as":[177],"reference":[179],"integrates":[181],"genetic":[183],"simulate":[186],"polymorphism.":[188],"To":[189],"test":[190],"performance,":[192],"did":[194],"lot":[196],"experiments":[198],"found":[200],"simulated":[202],"produced":[204],"by":[205],"GSDcreator":[206],"quit":[208],"mimic":[209],"data.":[214]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}