{"id":"https://openalex.org/W3005133755","doi":"https://doi.org/10.1109/bibm47256.2019.8983058","title":"Identifying Beta-Lactam Resistance with Neural Networks","display_name":"Identifying Beta-Lactam Resistance with Neural Networks","publication_year":2019,"publication_date":"2019-11-01","ids":{"openalex":"https://openalex.org/W3005133755","doi":"https://doi.org/10.1109/bibm47256.2019.8983058","mag":"3005133755"},"language":"en","primary_location":{"id":"doi:10.1109/bibm47256.2019.8983058","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm47256.2019.8983058","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081800708","display_name":"Cory Kromer-Edwards","orcid":"https://orcid.org/0000-0002-5804-8520"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cory Kromer-Edwards","raw_affiliation_strings":["Computer Science, University of Iowa, Iowa City, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science, University of Iowa, Iowa City, United States","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087843506","display_name":"Jace Neubaum","orcid":null},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jace Neubaum","raw_affiliation_strings":["Computer Science, University of Iowa, Iowa City, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science, University of Iowa, Iowa City, United States","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090034482","display_name":"Suely Oliveira","orcid":"https://orcid.org/0000-0003-4987-5353"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suely Oliveira","raw_affiliation_strings":["Computer Science, University of Iowa, Iowa City, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science, University of Iowa, Iowa City, United States","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069798980","display_name":"Caitlin J. Smith","orcid":null},"institutions":[{"id":"https://openalex.org/I4210121169","display_name":"JMI Laboratories","ror":"https://ror.org/02qv6pw23","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210121169"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caitlin Smith","raw_affiliation_strings":["JMI Laboratories, North Liberty, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"JMI Laboratories, North Liberty, United States","institution_ids":["https://openalex.org/I4210121169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083406242","display_name":"Evan Walser-Kuntz","orcid":"https://orcid.org/0000-0003-0142-1248"},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan Walser-Kuntz","raw_affiliation_strings":["Computer Science, University of Iowa, Iowa City, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science, University of Iowa, Iowa City, United States","institution_ids":["https://openalex.org/I126307644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013998480","display_name":"A.W. West","orcid":null},"institutions":[{"id":"https://openalex.org/I126307644","display_name":"University of Iowa","ror":"https://ror.org/036jqmy94","country_code":"US","type":"education","lineage":["https://openalex.org/I126307644"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew West","raw_affiliation_strings":["Computer Science, University of Iowa, Iowa City, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science, University of Iowa, Iowa City, United States","institution_ids":["https://openalex.org/I126307644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":null,"first_page":"1324","last_page":"1330"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antibiotics","display_name":"Antibiotics","score":0.7871390581130981},{"id":"https://openalex.org/keywords/bacteria","display_name":"Bacteria","score":0.733710765838623},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"Antibiotic resistance","score":0.6894469261169434},{"id":"https://openalex.org/keywords/resistance","display_name":"Resistance (ecology)","score":0.5206239223480225},{"id":"https://openalex.org/keywords/organism","display_name":"Organism","score":0.4785635769367218},{"id":"https://openalex.org/keywords/horizontal-gene-transfer","display_name":"Horizontal gene transfer","score":0.4710899293422699},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4426383972167969},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.4382963180541992},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.43320223689079285},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.42788949608802795},{"id":"https://openalex.org/keywords/biotechnology","display_name":"Biotechnology","score":0.3812832534313202},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.37189286947250366},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.34156298637390137},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3398593068122864},{"id":"https://openalex.org/keywords/microbiology","display_name":"Microbiology","score":0.338251531124115},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.22940370440483093},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.1789025068283081}],"concepts":[{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.7871390581130981},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.733710765838623},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.6894469261169434},{"id":"https://openalex.org/C57473165","wikidata":"https://www.wikidata.org/wiki/Q7315604","display_name":"Resistance (ecology)","level":2,"score":0.5206239223480225},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.4785635769367218},{"id":"https://openalex.org/C92938381","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Horizontal gene transfer","level":4,"score":0.4710899293422699},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4426383972167969},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.4382963180541992},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43320223689079285},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42788949608802795},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.3812832534313202},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.37189286947250366},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34156298637390137},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3398593068122864},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.338251531124115},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.22940370440483093},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.1789025068283081}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm47256.2019.8983058","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm47256.2019.8983058","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Peace, Justice and strong institutions","id":"https://metadata.un.org/sdg/16","score":0.47999998927116394}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1993397663","https://openalex.org/W2014802425","https://openalex.org/W2040584032","https://openalex.org/W2069659223","https://openalex.org/W2095705004","https://openalex.org/W2117767830","https://openalex.org/W2119561943","https://openalex.org/W2133733470","https://openalex.org/W2155524176","https://openalex.org/W2758908936","https://openalex.org/W6674330103"],"related_works":["https://openalex.org/W2955020749","https://openalex.org/W2029063045","https://openalex.org/W2507683919","https://openalex.org/W2076505260","https://openalex.org/W4226193097","https://openalex.org/W4320037900","https://openalex.org/W4297123388","https://openalex.org/W3032187068","https://openalex.org/W4221083638","https://openalex.org/W3152803520"],"abstract_inverted_index":{"Antibiotic":[0],"resistant":[1],"bacteria":[2,35,50,110],"are":[3],"an":[4,108],"ever-present":[5],"threat":[6],"in":[7,51,113,117,138],"today's":[8],"society":[9],"and":[10,18,27,85,96,132,136],"matter":[11],"of":[12,25],"great":[13],"concern":[14],"for":[15,63,107],"the":[16,22,28,49,57,76,104,114],"medical":[17],"scientific":[19],"communities.":[20],"With":[21],"high":[23,128],"frequency":[24],"mutations,":[26],"ability":[29],"to":[30,39,45,55,78,102],"transfer":[31],"genes":[32],"across":[33],"species,":[34],"can":[36],"acquire":[37],"resistance":[38,44,81,105],"currently":[40],"used":[41],"antibiotics.":[42],"Identifying":[43],"antibiotics":[46],"requires":[47],"growing":[48],"various":[52],"antibiotic":[53],"concentrations":[54],"determine":[56],"Minimum":[58],"Inhibitory":[59],"Concentration":[60],"(MIC)":[61],"value":[62],"that":[64,118,122],"bacteria-antibiotic":[65],"combination":[66,111],"which":[67],"is":[68,83],"a":[69,140],"longer":[70],"than":[71],"two":[72],"day":[73],"process.":[74],"Additionally,":[75],"testing":[77],"evaluate":[79],"genetic":[80],"determinants":[82],"cumbersome":[84],"demands":[86],"considerable":[87],"expertise.":[88],"This":[89],"paper":[90],"looks":[91],"at":[92],"Neural":[93],"Networks":[94],"(NN)":[95],"decision":[97,123,141],"trees":[98,124],"as":[99,127,130],"viable":[100],"options":[101],"predict":[103],"category":[106],"antibiotic,":[109],"based":[112],"beta-lactamases":[115],"present":[116],"organism.":[119],"We":[120],"show":[121],"have":[125],"just":[126],"accuracy":[129],"NN,":[131],"provide":[133],"more":[134],"detail":[135],"incite":[137],"how":[139],"was":[142],"made.":[143]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}