{"id":"https://openalex.org/W2913861934","doi":"https://doi.org/10.1109/bibm.2018.8621184","title":"Sequence-derived linear neighborhood propagation method for predicting lncRNA-miRNA interactions","display_name":"Sequence-derived linear neighborhood propagation method for predicting lncRNA-miRNA interactions","publication_year":2018,"publication_date":"2018-12-01","ids":{"openalex":"https://openalex.org/W2913861934","doi":"https://doi.org/10.1109/bibm.2018.8621184","mag":"2913861934"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2018.8621184","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2018.8621184","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100448121","display_name":"Wen Zhang","orcid":"https://orcid.org/0000-0001-5221-2628"},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wen Zhang","raw_affiliation_strings":["College of Informatics, Huazhong Agricultural University, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"College of Informatics, Huazhong Agricultural University, Wuhan, China","institution_ids":["https://openalex.org/I204823248"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012915515","display_name":"Guifeng Tang","orcid":null},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guifeng Tang","raw_affiliation_strings":["School of Computer Science, Wuhan University, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077699788","display_name":"Siman Wang","orcid":"https://orcid.org/0000-0002-5172-2682"},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siman Wang","raw_affiliation_strings":["School of Computer Science, Wuhan University, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101631972","display_name":"Yanlin Chen","orcid":"https://orcid.org/0000-0003-1323-3826"},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanlin Chen","raw_affiliation_strings":["School of Mathematics and Statistics, Wuhan University, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"School of Mathematics and Statistics, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090401365","display_name":"Shuang Zhou","orcid":"https://orcid.org/0009-0005-6374-4837"},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuang Zhou","raw_affiliation_strings":["School of Computer Science, Wuhan University, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100451521","display_name":"Xiaohong Li","orcid":"https://orcid.org/0000-0003-0959-3976"},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaohong Li","raw_affiliation_strings":["School of Computer Science, Wuhan University, Wuhan, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, Wuhan University, Wuhan, China","institution_ids":["https://openalex.org/I37461747"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5100448121"],"corresponding_institution_ids":["https://openalex.org/I204823248"],"apc_list":null,"apc_paid":null,"fwci":0.4759,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.59289903,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"50","last_page":"55"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6018947958946228},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.5969130396842957},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.5029527544975281},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4896102547645569},{"id":"https://openalex.org/keywords/interaction-information","display_name":"Interaction information","score":0.4775739014148712},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.47465330362319946},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.45910194516181946},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3944423794746399},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3401809334754944},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3208549916744232},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.26887935400009155},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.22807776927947998},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.21627265214920044},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.17916518449783325},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15023201704025269}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6018947958946228},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.5969130396842957},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5029527544975281},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4896102547645569},{"id":"https://openalex.org/C38764148","wikidata":"https://www.wikidata.org/wiki/Q17098245","display_name":"Interaction information","level":2,"score":0.4775739014148712},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.47465330362319946},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.45910194516181946},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3944423794746399},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3401809334754944},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3208549916744232},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.26887935400009155},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22807776927947998},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.21627265214920044},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.17916518449783325},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15023201704025269},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2018.8621184","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2018.8621184","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1161601223","https://openalex.org/W1508874165","https://openalex.org/W1570823782","https://openalex.org/W1985205042","https://openalex.org/W1986589033","https://openalex.org/W2023691360","https://openalex.org/W2026257220","https://openalex.org/W2032183472","https://openalex.org/W2046387002","https://openalex.org/W2077327925","https://openalex.org/W2108836814","https://openalex.org/W2111094216","https://openalex.org/W2117977572","https://openalex.org/W2124826140","https://openalex.org/W2258129851","https://openalex.org/W2278525075","https://openalex.org/W2336850185","https://openalex.org/W2508414719","https://openalex.org/W2520085705","https://openalex.org/W2570516417","https://openalex.org/W2572837991","https://openalex.org/W2575293459","https://openalex.org/W2752850911","https://openalex.org/W2766950760","https://openalex.org/W2767918570","https://openalex.org/W2776574140","https://openalex.org/W2780584018","https://openalex.org/W2805643613","https://openalex.org/W2810107880"],"related_works":["https://openalex.org/W2737319532","https://openalex.org/W4392896533","https://openalex.org/W2062945643","https://openalex.org/W2050308539","https://openalex.org/W3151405604","https://openalex.org/W4241694095","https://openalex.org/W2330252996","https://openalex.org/W2793648706","https://openalex.org/W3043187607","https://openalex.org/W2565797512"],"abstract_inverted_index":{"RNA-miRNA":[0],"interactions":[1,12,61,88,166,216],"play":[2],"key":[3],"roles":[4],"in":[5,206],"gene":[6],"regulatory":[7],"networks.":[8],"Predicting":[9],"novel":[10,60,200],"lncRNA-miRNA":[11,40,144,165,224],"can":[13,163],"advance":[14],"the":[15,19,24,59,122,128,136,148,178,192,214,218,223,228,234],"progress":[16],"of":[17,21,26,117,151,181],"understanding":[18],"functions":[20],"lncRNAs":[22,63,68,184],"and":[23,64,69,86,93,109,120,127,146,191,227],"mechanism":[25],"involved":[27],"complicated":[28],"diseases,":[29],"but":[30],"very":[31],"few":[32],"computational":[33,48],"methods":[34],"have":[35,74],"been":[36],"developed":[37],"for":[38,67,183,222],"predicting":[39],"interactions.":[41],"In":[42],"this":[43],"paper,":[44],"we":[45],"propose":[46],"a":[47],"method":[49,55],"named":[50],"sequence-derived":[51],"linear":[52,99,149],"neighborhood":[53,100],"propagation":[54,138],"(SLNPM)":[56],"to":[57,89,114,142,198],"predict":[58,164],"between":[62],"miRNAs,":[65],"especially":[66],"miRNAs":[70,186],"which":[71,202],"do":[72,203],"not":[73,204],"any":[75,188],"known":[76,87,189,215],"interaction.":[77],"First,":[78],"SLNPM":[79,104,134,162,182,196],"fully":[80],"exploits":[81],"lncRNA":[82,124],"sequences,":[83],"miRNA":[84,130],"sequences":[85],"calculate":[90],"lncRNA-lncRNA":[91,107],"similarities":[92,95,108,112],"miRNA-miRNA":[94,111],"by":[96],"using":[97],"fast":[98],"similarity":[101],"approach.":[102],"Then,":[103],"integrates":[105],"multiple":[106,110],"respectively":[113],"make":[115],"use":[116],"diverse":[118],"information,":[119],"constructs":[121],"integrated":[123,129],"similarity-based":[125,131],"graph":[126],"graph.":[132],"Finally,":[133],"implements":[135],"label":[137],"process":[139],"on":[140],"graphs":[141],"score":[143],"pairs,":[145],"adopts":[147],"combination":[150],"their":[152],"outputs":[153],"as":[154],"final":[155],"predictions.":[156],"The":[157],"experimental":[158],"results":[159,193],"demonstrate":[160],"that":[161,195,213],"with":[167,171],"higher":[168],"accuracy":[169],"compared":[170],"other":[172],"state-of-the-art":[173],"methods.":[174],"We":[175],"also":[176],"analyze":[177],"prediction":[179],"capability":[180],"or":[185],"without":[187],"interaction,":[190],"indicate":[194],"helps":[197],"find":[199],"interactions,":[201],"exist":[205],"our":[207,210],"dataset.":[208],"Moreover,":[209],"studies":[211],"reveal":[212],"provide":[217],"most":[219],"important":[220],"information":[221,231],"interaction":[225],"prediction,":[226],"incorporating":[229],"sequence":[230],"further":[232],"improves":[233],"performance.":[235]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}