{"id":"https://openalex.org/W2774462213","doi":"https://doi.org/10.1109/bibm.2017.8217992","title":"NanoStringBioNet: Integrated R framework for bioscience knowledge discovery from NanoString nCounter data","display_name":"NanoStringBioNet: Integrated R framework for bioscience knowledge discovery from NanoString nCounter data","publication_year":2017,"publication_date":"2017-11-01","ids":{"openalex":"https://openalex.org/W2774462213","doi":"https://doi.org/10.1109/bibm.2017.8217992","mag":"2774462213"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2017.8217992","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2017.8217992","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048065612","display_name":"Mariah Hoffman","orcid":"https://orcid.org/0000-0002-0509-3408"},"institutions":[{"id":"https://openalex.org/I22555787","display_name":"University of Sioux Falls","ror":"https://ror.org/05ndpad60","country_code":"US","type":"education","lineage":["https://openalex.org/I22555787"]},{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mariah M. Hoffman","raw_affiliation_strings":["Biomedical Engineering, University of South Dakota, Sioux Falls, SD"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, University of South Dakota, Sioux Falls, SD","institution_ids":["https://openalex.org/I22555787","https://openalex.org/I189957204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005230782","display_name":"Carrie J. Minette","orcid":"https://orcid.org/0000-0002-6641-4527"},"institutions":[{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carrie J. Minette","raw_affiliation_strings":["Department of Computer Science, University of South Dakota, Vermillion, SD"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of South Dakota, Vermillion, SD","institution_ids":["https://openalex.org/I189957204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020015400","display_name":"Shanta M. Messerli","orcid":null},"institutions":[{"id":"https://openalex.org/I4210095855","display_name":"Sanford Research","ror":"https://ror.org/00sfn8y78","country_code":"US","type":"facility","lineage":["https://openalex.org/I1305840828","https://openalex.org/I4210095855"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shanta M. Messerli","raw_affiliation_strings":["Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD"],"affiliations":[{"raw_affiliation_string":"Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD","institution_ids":["https://openalex.org/I4210095855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112176347","display_name":"Ratan D. Bhardwaj","orcid":null},"institutions":[{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ratan D. Bhardwaj","raw_affiliation_strings":["University of South Dakota, Vermillion, SD, US"],"affiliations":[{"raw_affiliation_string":"University of South Dakota, Vermillion, SD, US","institution_ids":["https://openalex.org/I189957204"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003549657","display_name":"Etienne Z. Gnimpi\u00e9ba","orcid":"https://orcid.org/0000-0002-5338-084X"},"institutions":[{"id":"https://openalex.org/I22555787","display_name":"University of Sioux Falls","ror":"https://ror.org/05ndpad60","country_code":"US","type":"education","lineage":["https://openalex.org/I22555787"]},{"id":"https://openalex.org/I189957204","display_name":"University of South Dakota","ror":"https://ror.org/0043h8f16","country_code":"US","type":"education","lineage":["https://openalex.org/I189957204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Etienne Z. Gnimpieba","raw_affiliation_strings":["Biomedical Engineering, University of South Dakota, Sioux Falls, SD"],"affiliations":[{"raw_affiliation_string":"Biomedical Engineering, University of South Dakota, Sioux Falls, SD","institution_ids":["https://openalex.org/I22555787","https://openalex.org/I189957204"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5048065612"],"corresponding_institution_ids":["https://openalex.org/I189957204","https://openalex.org/I22555787"],"apc_list":null,"apc_paid":null,"fwci":0.1063,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.50001553,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"15","issue":null,"first_page":"2157","last_page":"2162"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6980816721916199},{"id":"https://openalex.org/keywords/raw-data","display_name":"Raw data","score":0.6105765700340271},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5822020173072815},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.45549213886260986},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4248442053794861},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.3240751624107361},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.21088847517967224},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.10919719934463501}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6980816721916199},{"id":"https://openalex.org/C132964779","wikidata":"https://www.wikidata.org/wiki/Q2110223","display_name":"Raw data","level":2,"score":0.6105765700340271},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5822020173072815},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.45549213886260986},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4248442053794861},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.3240751624107361},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.21088847517967224},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.10919719934463501}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2017.8217992","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2017.8217992","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1519397402","https://openalex.org/W1813388215","https://openalex.org/W1944603233","https://openalex.org/W1990905996","https://openalex.org/W1995830102","https://openalex.org/W2009847758","https://openalex.org/W2088170018","https://openalex.org/W2096173332","https://openalex.org/W2121044470","https://openalex.org/W2134179844","https://openalex.org/W2135061646","https://openalex.org/W2135256913","https://openalex.org/W2170111518","https://openalex.org/W2171523622","https://openalex.org/W2189254770","https://openalex.org/W2294516783","https://openalex.org/W2319824849","https://openalex.org/W2406250479","https://openalex.org/W2500951036","https://openalex.org/W2537802567","https://openalex.org/W2583708328","https://openalex.org/W2607781059","https://openalex.org/W3214074647","https://openalex.org/W4294141750","https://openalex.org/W4399538195","https://openalex.org/W4399639731","https://openalex.org/W6678230397"],"related_works":["https://openalex.org/W2055243143","https://openalex.org/W4252510819","https://openalex.org/W3012838233","https://openalex.org/W4321636575","https://openalex.org/W2357796999","https://openalex.org/W2045526782","https://openalex.org/W2741131631","https://openalex.org/W1986418932","https://openalex.org/W2156919374","https://openalex.org/W2508885301"],"abstract_inverted_index":{"The":[0],"NanoString":[1,90],"nCounter":[2,55,80],"Analysis":[3],"System":[4],"is":[5,13,60],"a":[6,61,68,88],"medium-throughput":[7],"gene":[8,117],"expression":[9],"quantification":[10],"technique":[11],"that":[12,66],"becoming":[14],"increasingly":[15],"popular":[16],"in":[17,33,45,95],"the":[18,34,42,51,83,101],"fields":[19],"of":[20,28,36,54,63,113],"immunology":[21],"and":[22,30,75,92,110,125],"oncology":[23],"due":[24],"to":[25],"its":[26],"ease":[27],"use":[29],"sensitivity,":[31],"particularly":[32],"analysis":[35,48,53,123],"formalin-fixed":[37],"paraffin":[38],"embedded":[39],"samples.":[40],"Despite":[41],"growing":[43],"interest":[44],"NanoString,":[46],"systematic":[47,76],"frameworks":[49],"for":[50,73,98],"reproducible":[52],"data":[56,122],"remain":[57],"limited.":[58],"NanoStringBioNet":[59,86],"pair":[62],"R":[64],"packages":[65],"form":[67],"semi-automatic,":[69],"open":[70],"source":[71],"framework":[72],"integrative":[74],"knowledge":[77],"discovery":[78],"from":[79],"datasets.":[81],"Using":[82],"NSData":[84],"module,":[85],"preprocesses":[87],"raw":[89],"dataset":[91],"stores":[93],"it":[94],"Biobase":[96],"format":[97],"sharability.":[99],"Subsequently,":[100],"NSFunc":[102],"module":[103],"performs":[104],"downstream":[105],"analyses":[106],"such":[107],"as":[108],"enrichment":[109],"network":[111],"inference":[112],"stable":[114],"differentially":[115],"expressed":[116],"clusters":[118],"by":[119],"leveraging":[120],"existing":[121],"tools":[124],"custom":[126],"script.":[127]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}