{"id":"https://openalex.org/W2771223089","doi":"https://doi.org/10.1109/bibm.2017.8217978","title":"A systems biology approach for modeling microbiomes using split graphs","display_name":"A systems biology approach for modeling microbiomes using split graphs","publication_year":2017,"publication_date":"2017-11-01","ids":{"openalex":"https://openalex.org/W2771223089","doi":"https://doi.org/10.1109/bibm.2017.8217978","mag":"2771223089"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2017.8217978","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2017.8217978","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100365913","display_name":"Suyeon Kim","orcid":"https://orcid.org/0000-0001-9338-3132"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Suyeon Kim","raw_affiliation_strings":["College of Information Science and Technology, University of Nebraska at Omaha, Omaha, NE, USA"],"affiliations":[{"raw_affiliation_string":"College of Information Science and Technology, University of Nebraska at Omaha, Omaha, NE, USA","institution_ids":["https://openalex.org/I122266389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008692578","display_name":"Ishwor Thapa","orcid":"https://orcid.org/0000-0002-3594-1631"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ishwor Thapa","raw_affiliation_strings":["College of Information Science and Technology, University of Nebraska at Omaha, Omaha, NE, USA"],"affiliations":[{"raw_affiliation_string":"College of Information Science and Technology, University of Nebraska at Omaha, Omaha, NE, USA","institution_ids":["https://openalex.org/I122266389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011725095","display_name":"Guoqing Lu","orcid":"https://orcid.org/0000-0002-2728-9604"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guoqing Lu","raw_affiliation_strings":["Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA","institution_ids":["https://openalex.org/I122266389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040607121","display_name":"Lifeng Zhu","orcid":"https://orcid.org/0000-0002-0589-4256"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lifeng Zhu","raw_affiliation_strings":["Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA","institution_ids":["https://openalex.org/I122266389"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047703641","display_name":"Hesham Ali","orcid":"https://orcid.org/0000-0001-6675-7987"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hesham H Ali","raw_affiliation_strings":["College of Information Science and Technology, University of Nebraska at Omaha, Omaha, NE, USA"],"affiliations":[{"raw_affiliation_string":"College of Information Science and Technology, University of Nebraska at Omaha, Omaha, NE, USA","institution_ids":["https://openalex.org/I122266389"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100365913"],"corresponding_institution_ids":["https://openalex.org/I122266389"],"apc_list":null,"apc_paid":null,"fwci":0.2127,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.55160599,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"334","issue":null,"first_page":"2062","last_page":"2068"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11791","display_name":"Microbial Community Ecology and Physiology","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microbiome","display_name":"Microbiome","score":0.8870682716369629},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6765322685241699},{"id":"https://openalex.org/keywords/fish-actinopterygii","display_name":"Fish <Actinopterygii>","score":0.6046708822250366},{"id":"https://openalex.org/keywords/abundance","display_name":"Abundance (ecology)","score":0.5069010853767395},{"id":"https://openalex.org/keywords/ecosystem","display_name":"Ecosystem","score":0.500542163848877},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.37834808230400085},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.35685738921165466},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.13661763072013855},{"id":"https://openalex.org/keywords/fishery","display_name":"Fishery","score":0.07335904240608215}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.8870682716369629},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6765322685241699},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.6046708822250366},{"id":"https://openalex.org/C77077793","wikidata":"https://www.wikidata.org/wiki/Q336019","display_name":"Abundance (ecology)","level":2,"score":0.5069010853767395},{"id":"https://openalex.org/C110872660","wikidata":"https://www.wikidata.org/wiki/Q37813","display_name":"Ecosystem","level":2,"score":0.500542163848877},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.37834808230400085},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.35685738921165466},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.13661763072013855},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.07335904240608215}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2017.8217978","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2017.8217978","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W64675103","https://openalex.org/W1523266228","https://openalex.org/W1644749979","https://openalex.org/W1982559407","https://openalex.org/W1994319056","https://openalex.org/W2047663757","https://openalex.org/W2072970694","https://openalex.org/W2100318643","https://openalex.org/W2111823238","https://openalex.org/W2131026689","https://openalex.org/W2144114946","https://openalex.org/W2144240290","https://openalex.org/W2147565107","https://openalex.org/W2153683423","https://openalex.org/W2159482845","https://openalex.org/W2162088497","https://openalex.org/W2163813680","https://openalex.org/W2165700458","https://openalex.org/W2167062509","https://openalex.org/W2274241954","https://openalex.org/W2404873889","https://openalex.org/W2417065404","https://openalex.org/W2428898156","https://openalex.org/W2482481188","https://openalex.org/W2588997555","https://openalex.org/W2911479728","https://openalex.org/W2952564192","https://openalex.org/W4294216483","https://openalex.org/W6694579151","https://openalex.org/W6722418964"],"related_works":["https://openalex.org/W2552736322","https://openalex.org/W2801453188","https://openalex.org/W2488006949","https://openalex.org/W2766316008","https://openalex.org/W2890512197","https://openalex.org/W2110805509","https://openalex.org/W2051704857","https://openalex.org/W2784097778","https://openalex.org/W2548148008","https://openalex.org/W2762473741","https://openalex.org/W2770357832","https://openalex.org/W3201902793","https://openalex.org/W3212809943","https://openalex.org/W2989632277","https://openalex.org/W2076432480","https://openalex.org/W2280650020","https://openalex.org/W2949624116","https://openalex.org/W1966809619","https://openalex.org/W2556003929","https://openalex.org/W2182957646"],"abstract_inverted_index":{"With":[0],"the":[1,23,65,70,76,94,119,134,155,176],"recent":[2],"advances":[3],"in":[4,27,37,83,98,118,150],"sequencing":[5],"technology,":[6],"researchers":[7],"now":[8],"have":[9,20],"opportunities":[10],"to":[11,63,93,166,175],"study":[12,91,135],"microbiomes":[13,26,68,97],"associated":[14,84,145],"with":[15,146],"various":[16,105],"environments.":[17,85],"Recent":[18],"studies":[19],"shown":[21],"that":[22,137,162],"composition":[24,66,74,95],"of":[25,43,48,67,72,80,96,111,133,141,154,169],"our":[28,31,38],"bodies":[29],"and":[30,69,78,101,127,172],"environments":[32],"play":[33],"a":[34,56,89],"significant":[35],"role":[36],"health.":[39],"For":[40],"example,":[41],"90%":[42],"human":[44],"DNA":[45],"is":[46],"composed":[47],"bacterial":[49,160],"microbiomes.":[50],"In":[51],"this":[52],"study,":[53],"we":[54],"propose":[55],"systems":[57],"biology":[58],"approach":[59],"using":[60],"split":[61],"graphs":[62],"analyze":[64],"impact":[71,103],"such":[73],"on":[75,88,104],"health":[77],"growth":[79,106,148],"organisms":[81],"living":[82],"We":[86,157],"focus":[87],"case":[90],"related":[92],"fish":[99,177],"guts":[100],"its":[102,125],"parameters":[107],"for":[108],"three":[109],"types":[110],"fish.":[112,156],"The":[113,131],"proposed":[114],"model":[115],"explores":[116],"features":[117],"aquatic":[120],"ecosystem":[121],"including":[122],"correlations":[123],"among":[124],"microorganisms":[126],"their":[128,173],"abundance":[129],"levels.":[130],"results":[132],"show":[136],"single":[138],"or":[139],"groups":[140],"bacteria":[142,171],"are":[143],"significantly":[144],"multiple":[147],"phenotypes":[149],"different":[151],"gut":[152,178],"portions":[153],"also":[158],"identify":[159],"clusters":[161],"provide":[163],"new":[164],"insight":[165],"functional":[167],"relevance":[168],"these":[170],"contribution":[174],"microbial":[179],"ecosystem.":[180]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
