{"id":"https://openalex.org/W3160213169","doi":"https://doi.org/10.1109/bibm.2016.7822765","title":"DisSetSim: An online system for calculating similarity between disease sets","display_name":"DisSetSim: An online system for calculating similarity between disease sets","publication_year":2016,"publication_date":"2016-12-01","ids":{"openalex":"https://openalex.org/W3160213169","doi":"https://doi.org/10.1109/bibm.2016.7822765","mag":"3160213169"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2016.7822765","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2016.7822765","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037178137","display_name":"Yang Hu","orcid":null},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yang Hu","raw_affiliation_strings":["School of Life Science and Technology, Harbin Institute of Technology, 150001, China","School of Life Science and Technology, Harbin Institute of Technology, Harbin, PR China"],"affiliations":[{"raw_affiliation_string":"School of Life Science and Technology, Harbin Institute of Technology, 150001, China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"School of Life Science and Technology, Harbin Institute of Technology, Harbin, PR China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012585076","display_name":"Lingling Zhao","orcid":"https://orcid.org/0000-0002-2808-3771"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingling Zhao","raw_affiliation_strings":["Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078678693","display_name":"Zhiyan Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiyan Liu","raw_affiliation_strings":["Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047481703","display_name":"Hong Ju","orcid":null},"institutions":[{"id":"https://openalex.org/I4210115771","display_name":"Heilongjiang Academy of Forestry","ror":"https://ror.org/02bfrg439","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210115771"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Ju","raw_affiliation_strings":["Department of information engineering, Heilongjiang biological science and technology Career Academy, Harbin 150001, China"],"affiliations":[{"raw_affiliation_string":"Department of information engineering, Heilongjiang biological science and technology Career Academy, Harbin 150001, China","institution_ids":["https://openalex.org/I4210115771"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101590381","display_name":"Hongbo Shi","orcid":"https://orcid.org/0000-0002-0538-3026"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongbo Shi","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, 150001, China","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, PR China"],"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, 150001, China","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, PR China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027448745","display_name":"Peigang Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peigang Xu","raw_affiliation_strings":["Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100392447","display_name":"Yadong Wang","orcid":"https://orcid.org/0000-0001-6500-6217"},"institutions":[{"id":"https://openalex.org/I204983213","display_name":"Harbin Institute of Technology","ror":"https://ror.org/01yqg2h08","country_code":"CN","type":"education","lineage":["https://openalex.org/I204983213"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yadong Wang","raw_affiliation_strings":["Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, 150001, China","institution_ids":["https://openalex.org/I204983213"]},{"raw_affiliation_string":"Department of Computer Science and Technology, Harbin Institute of Technology, Harbin, PR China","institution_ids":["https://openalex.org/I204983213"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052382857","display_name":"Liang Cheng","orcid":"https://orcid.org/0000-0002-6665-6710"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Cheng","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University, 150001, China","College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, PR China"],"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, 150001, China","institution_ids":["https://openalex.org/I156144747"]},{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, PR China","institution_ids":["https://openalex.org/I156144747"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5037178137"],"corresponding_institution_ids":["https://openalex.org/I204983213"],"apc_list":null,"apc_paid":null,"fwci":0.1667,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.65589068,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1641","last_page":"1652"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7222938537597656},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.6687573194503784},{"id":"https://openalex.org/keywords/information-retrieval","display_name":"Information retrieval","score":0.40165138244628906},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3396194577217102}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7222938537597656},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.6687573194503784},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.40165138244628906},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3396194577217102},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2016.7822765","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2016.7822765","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W611910056","https://openalex.org/W1552716293","https://openalex.org/W1647729745","https://openalex.org/W1977878983","https://openalex.org/W2002185065","https://openalex.org/W2019818248","https://openalex.org/W2023361805","https://openalex.org/W2048296798","https://openalex.org/W2054674225","https://openalex.org/W2083045667","https://openalex.org/W2084168100","https://openalex.org/W2085565204","https://openalex.org/W2103017472","https://openalex.org/W2108491719","https://openalex.org/W2109473868","https://openalex.org/W2117243134","https://openalex.org/W2124001239","https://openalex.org/W2125118217","https://openalex.org/W2128049108","https://openalex.org/W2135505914","https://openalex.org/W2141222510","https://openalex.org/W2143076797","https://openalex.org/W2158135353","https://openalex.org/W2159092541","https://openalex.org/W2162142896","https://openalex.org/W2163118979","https://openalex.org/W2194675750","https://openalex.org/W2345181615","https://openalex.org/W2437043110","https://openalex.org/W2462108616","https://openalex.org/W2505478609","https://openalex.org/W2511335635","https://openalex.org/W2512308096","https://openalex.org/W2512938483","https://openalex.org/W2517328844","https://openalex.org/W2549247408","https://openalex.org/W2582585762","https://openalex.org/W2950225692","https://openalex.org/W6633256644","https://openalex.org/W6636975626","https://openalex.org/W6677712588","https://openalex.org/W6732742156"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W4391913857","https://openalex.org/W2350741829","https://openalex.org/W2530322880"],"abstract_inverted_index":{"Functional":[0],"similarity":[1,37,79,109],"between":[2],"molecules":[3,22],"results":[4,119],"in":[5,60],"similar":[6],"phenotypes,":[7],"such":[8],"as":[9],"diseases.":[10,27],"Therefore,":[11],"it":[12],"is":[13],"an":[14,53],"effective":[15],"way":[16],"to":[17,56,76,94,123],"reveal":[18],"the":[19,29,36,78,96,99,107,132,146],"function":[20],"of":[21,31,39,47,81,110],"based":[23,112,139],"on":[24,113,140],"their":[25,114],"induced":[26,115],"However,":[28],"lack":[30],"a":[32,150,156],"tool":[33],"for":[34,105],"obtaining":[35],"score":[38,80],"pair-wise":[40,82],"disease":[41,116],"sets":[42],"(SSDS)":[43],"limits":[44],"this":[45,58,61],"type":[46],"application.":[48],"Here,":[49],"we":[50],"introduce":[51],"DisSetSim,":[52],"online":[54],"system":[55,102,162],"solve":[57],"problem":[59],"article.":[62],"Five":[63],"state-of-the-art":[64],"methods":[65,73],"involving":[66],"Resnik's,":[67],"Lin's,":[68],"Wang's,":[69],"PSB,":[70],"and":[71,155],"SemFunSim":[72],"were":[74,120],"implemented":[75,93],"measure":[77],"diseases":[83],"(SSD)":[84],"first.":[85],"And":[86],"then":[87],"\u201cpair-wise-best":[88],"pairs-average\u201d":[89],"(PWBPA)":[90],"method":[91,148],"was":[92,103],"calculated":[95],"SSDS":[97],"by":[98],"SSD.":[100],"The":[101,118,128,161],"applied":[104],"calculating":[106],"functional":[108],"miRNAs":[111],"sets.":[117],"further":[121],"used":[122],"predict":[124],"potential":[125],"disease-miRNA":[126],"relationships.":[127],"high":[129,151],"area":[130],"under":[131],"receiver":[133],"operating":[134],"characteristic":[135],"curve":[136],"AUC":[137],"(0.9296)":[138],"leave-one-out":[141],"cross":[142],"validation":[143],"shows":[144],"that":[145],"PWBPA":[147],"achieves":[149],"true":[152],"positive":[153,159],"rate":[154],"low":[157],"false":[158],"rate.":[160],"can":[163],"be":[164],"accessed":[165],"from":[166],"http://bio-annotation.cn/DisSetSim.":[167]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1}],"updated_date":"2026-01-29T23:13:10.619473","created_date":"2025-10-10T00:00:00"}